Marc Loriaux

Associate Professor

  • 4949 Citations
  • 32 h-Index
1991 …2019
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Research Output 1991 2019

  • 4949 Citations
  • 32 h-Index
  • 73 Article
  • 1 Letter
1991
170 Citations (Scopus)

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A

Rehfuss, R. P., Walton, K. M., Loriaux, M. & Goodman, R., Oct 5 1991, In : Journal of Biological Chemistry. 266, 28, p. 18431-18434 4 p.

Research output: Contribution to journalArticle

Transcription
Cyclic AMP-Dependent Protein Kinases
Carrier Proteins
CREB-Binding Protein
Phosphorylation
1993
47 Citations (Scopus)
Leucine Zippers
Phosphorylation
Basic-Leucine Zipper Transcription Factors
Transcriptional Activation
Proteins
1994
32 Citations (Scopus)

Modulatory function of CREB·CREMα heterodimers depends upon CREMα phosphorylation

Loriaux, M., Brennan, R. G. & Goodman, R., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 28839-28843 5 p.

Research output: Contribution to journalArticle

Phosphorylation
Cyclic AMP-Dependent Protein Kinases
Carrier Proteins
Chemical activation
Proteins
1998
24 Citations (Scopus)

Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine

Bloch, R., Pavcnik, D., Uchida, B., Krajina, A., Kamino, T., Timmermans, H., Loriaux, M. & Hulek, P., Nov 1998, In : CardioVascular and Interventional Radiology. 21, 6, p. 497-500 4 p.

Research output: Contribution to journalArticle

Polyethylene Terephthalates
Polyurethanes
Transjugular Intrahepatic Portasystemic Shunt
Swine
Stents
1999
52 Citations (Scopus)

Stent-grafts for de novo TIPS: Technique and early results

Andrews, R. T., Saxon, R. R., Bloch, R. D., Petersen, B., Uchida, B., Rabkin, J. M., Loriaux, M., Keller, F. & Rosch, J., 1999, In : Journal of Vascular and Interventional Radiology. 10, 10, p. 1371-1378 8 p.

Research output: Contribution to journalArticle

Transjugular Intrahepatic Portasystemic Shunt
Stents
Polytetrafluoroethylene
Transplants
Pathologic Constriction
2000
15 Citations (Scopus)

The square stent-based large vessel occluder: An experimental pilot study

Pavcnik, D., Uchida, B., Timmermans, H., Corless, C., Loriaux, M., Keller, F. & Rosch, J., 2000, In : Journal of Vascular and Interventional Radiology. 11, 9, p. 1227-1234 8 p.

Research output: Contribution to journalArticle

Small Intestine
Stents
Angiography
Swine
Catheters
2001
7 Citations (Scopus)

Bifurcated drum occluder endograft for treatment of abdominal aortic aneurysm: An experimental study in dogs

Pavcnik, D., Uchida, B., Timmermans, H., Petersen, B., Loriaux, M., Yamakado, K., Voda, J., Yin, Q. M., Keller, F. & Rosch, J., 2001, In : Journal of Vascular and Interventional Radiology. 12, 3, p. 359-364 6 p.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Dogs
Stents
Iliac Artery
Polytetrafluoroethylene
2002
4 Citations (Scopus)

Lack of suitability of the rabbit model for particulate uterine artery embolization

Binkert, C. A., Andrews, R. T., Pavcnik, D., Uchida, B., Loriaux, M., Toyota, N. & Rosch, J., 2002, In : Journal of Vascular and Interventional Radiology. 13, 6, p. 609-612 4 p.

Research output: Contribution to journalArticle

Uterine Artery Embolization
Rabbits
Polyvinyl Alcohol
Uterine Artery
Pregnancy
2003
13 Citations (Scopus)

c-CBL is not required for leukemia induction by Bcr-Abl in mice

Dinulescu, D. M., Wood, L., Shen, L., Loriaux, M., Corless, C., Gross, A. W., Ren, R., Deininger, M. W. N. & Druker, B., Dec 4 2003, In : Oncogene. 22, 55, p. 8852-8860 9 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-cbl
Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
bcr-abl Fusion Proteins
Cell Line
100 Citations (Scopus)
Philadelphia Chromosome
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cytogenetics
Clone Cells
Metaphase
2004
61 Citations (Scopus)

Clonal cytogenetic abnormalities in Philadelphia chromosome negative cells in chronic myeloid leukemia patients treated with imatinib

Loriaux, M. & Deininger, M., Nov 2004, In : Leukemia and Lymphoma. 45, 11, p. 2197-2203 7 p.

Research output: Contribution to journalArticle

Philadelphia Chromosome
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chromosome Aberrations
Clonal Evolution
Cytogenetics
5 Citations (Scopus)

Fallopian tube occlusion with use of a small intestine submucosa device: Evaluation in a rabbit model

Binkert, C. A., Pavcnik, D., Andrews, R. T., Loriaux, M., Uchida, B., Brountzos, E. N. & Rosch, J., Jun 2004, In : Journal of Vascular and Interventional Radiology. 15, 6, p. 609-613 5 p.

Research output: Contribution to journalArticle

Fallopian Tubes
Small Intestine
Rabbits
Equipment and Supplies
Hysterosalpingography
7 Citations (Scopus)

Ph-positive and -negative myeloproliferative syndromes may co-exist [1]

Mauro, M. J., Loriaux, M. & Deininger, M. W., Jul 2004, In : Leukemia. 18, 7, p. 1305-1307 3 p.

Research output: Contribution to journalArticle

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Bone Marrow Examination
Myeloproliferative Disorders
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Clone Cells
2005
289 Citations (Scopus)

The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia

Levine, R. L., Loriaux, M., Huntly, B. J. P., Loh, M. L., Beran, M., Stoffregen, E., Berger, R., Clark, J. J., Willis, S. G., Nguyen, K. T., Flores, N. J., Estey, E., Gattermann, N., Armstrong, S., Look, A. T., Griffin, J. D., Bernard, O. A., Heinrich, M., Gilliland, D. G., Druker, B. & 1 others, Deininger, M. W. N., Nov 15 2005, In : Blood. 106, 10, p. 3377-3379 3 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
T-cells
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
2006
240 Citations (Scopus)

Activating alleles of JAK3 in acute megakaryoblastic leukemia

Walters, D. K., Mercher, T., Gu, T. L., O'Hare, T., Tyner, J., Loriaux, M., Goss, V. L., Lee, K. A., Eide, C. A., Wong, M. J., Stoffregen, E. P., McGreevey, L., Nardone, J., Moore, S. A., Crispino, J., Boggon, T. J., Heinrich, M., Deininger, M. W., Polakiewicz, R. D., Gilliland, D. G. & 1 others, Druker, B., Jul 2006, In : Cancer Cell. 10, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Leukemia, Megakaryoblastic, Acute
Alleles
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Mutation
9 Citations (Scopus)

Acute graft-versus-host disease of the heart

Roberts, S. S., Leeborg, N., Loriaux, M., Johnson, F. L., Huang, M. L., Stenzel, P., Thiede, C. & Godder, K. T., Oct 15 2006, In : Pediatric Blood and Cancer. 47, 5, p. 624-628 5 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Bone Marrow Transplantation
Pediatrics
Chimerism
Gastrointestinal Tract
151 Citations (Scopus)

Characterization of murine JAK2V617F-positive myeloproliferative disease

Bumm, T. G. P., Elsea, C., Corbin, A. S., Loriaux, M., Sherbenou, D., Wood, L., Deininger, J., Silver, R. T., Druker, B. & Deininger, M. W. N., Dec 1 2006, In : Cancer Research. 66, 23, p. 11156-11165 10 p.

Research output: Contribution to journalArticle

Megakaryocyte-Erythroid Progenitor Cells
Myeloproliferative Disorders
Polycythemia Vera
Polycythemia
Primary Myelofibrosis
15 Citations (Scopus)

Establishment of a murine model of aggressive systemic mastocytosis/mast cell leukemia

Demehri, S., Corbin, A., Loriaux, M., Druker, B. & Deininger, M. W., Mar 2006, In : Experimental Hematology. 34, 3, p. 284-288 5 p.

Research output: Contribution to journalArticle

Mast-Cell Leukemia
Systemic Mastocytosis
Mastocytoma
Inbred DBA Mouse
Rare Diseases
2007
126 Citations (Scopus)

Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles

Fröhling, S., Scholl, C., Levine, R. L., Loriaux, M., Boggon, T. J., Bernard, O. A., Berger, R., Döhner, H., Döhner, K., Ebert, B. L., Teckie, S., Golub, T. R., Jiang, J., Schittenhelm, M. M., Lee, B. H., Griffin, J. D., Stone, R. M., Heinrich, M., Deininger, M. W., Druker, B. & 1 others, Gilliland, D. G., Dec 6 2007, In : Cancer Cell. 12, 6, p. 501-513 13 p.

Research output: Contribution to journalArticle

DNA Sequence Analysis
Alleles
Mutation
Phosphotransferases
Catalytic Domain
2008
45 Citations (Scopus)

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease

Agarwal, A., Bumm, T. G. P., Corbin, A. S., O'Hare, T., Loriaux, M., Van Dyke, J., Willis, S. G., Deininger, J., Nakayama, K. I., Druker, B. & Deininger, M. W., Sep 1 2008, In : Blood. 112, 5, p. 1960-1970 11 p.

Research output: Contribution to journalArticle

S-Phase Kinase-Associated Proteins
Bone Marrow
Cells
F-Box Proteins
Transformed Cell Line
74 Citations (Scopus)

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

Loriaux, M., Levine, R. L., Tyner, J., Fröhling, S., Scholl, C., Stoffregen, E. P., Wernig, G., Erickson, H., Eide, C. A., Berger, R., Bernard, O. A., Griffin, J. D., Stone, R. M., Lee, B., Meyerson, M., Heinrich, M., Deininger, M. W., Gilliland, D. G. & Druker, B., May 1 2008, In : Blood. 111, 9, p. 4788-4796 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Sequence Analysis
Tyrosine
Alleles
57 Citations (Scopus)

RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia

Tyner, J., Walters, D. K., Willis, S. G., Luttropp, M., Oost, J., Loriaux, M., Erickson, H., Corbin, A. S., O'Hare, T., Heinrich, M., Deininger, M. W. & Druker, B., Feb 15 2008, In : Blood. 111, 4, p. 2238-2245 8 p.

Research output: Contribution to journalArticle

RNA Interference
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Tyrosine
Screening
2009
20 Citations (Scopus)

A BCR-ABL Mutant Lacking Direct Binding Sites for the GRB2, CBL and CRKL Adapter Proteins Fails to Induce Leukemia in Mice

Johnson, K. J., Griswold, I. J., O'Hare, T., Corbin, A. S., Loriaux, M., Deininger, M. W. & Druker, B., 2009, In : PLoS One. 4, 10, e0007439.

Research output: Contribution to journalArticle

leukemia
binding sites
Leukemia
Binding Sites
myeloid leukemia
686 Citations (Scopus)

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

O'Hare, T., Shakespeare, W. C., Zhu, X., Eide, C. A., Rivera, V. M., Wang, F., Adrian, L. T., Zhou, T., Huang, W. S., Xu, Q., Metcalf, C. A., Tyner, J., Loriaux, M., Corbin, A. S., Wardwell, S., Ning, Y., Keats, J. A., Wang, Y., Sundaramoorthi, R., Thomas, M. & 8 others, Zhou, D., Snodgrass, J., Commodore, L., Sawyer, T. K., Dalgarno, D. C., Deininger, M. W. N., Druker, B. & Clackson, T., Nov 6 2009, In : Cancer Cell. 16, 5, p. 401-412 12 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Mutation
Phosphotransferases
Therapeutics
Mutagenesis
4 Citations (Scopus)

Functional characterization of an activating TEK mutation in acute myeloid leukemia: A cellular context-dependent activating mutation

Tyner, J., Rutenberg-Schoenberg, M. L., Erickson, H., Willis, S. G., O'Hare, T., Deininger, M. W., Druker, B. & Loriaux, M., 2009, In : Leukemia. 23, 7, p. 1345-1348 4 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Mutation
9 Citations (Scopus)

High-throughput mutational screen of the tyrosine kinome in chronic myelomonocytic leukemia

Tyner, J., Loriaux, M., Erickson, H., Eide, C. A., Deininger, J., MacPartlin, M., Willis, S. G., Lange, T., Druker, B., Kovacsovics, T., Maziarz, R., Gattermann, N. & Deininger, M. W., 2009, In : Leukemia. 23, 2, p. 406-409 4 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Leukemia, Myelomonocytic, Chronic
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Proteomics
Protein-Tyrosine Kinases
83 Citations (Scopus)

High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

Tyner, J., Erickson, H., Deininger, M. W. N., Willis, S. G., Eide, C. A., Levine, R. L., Heinrich, M., Gattermann, N., Gilliland, D. G., Druker, B. & Loriaux, M., Feb 19 2009, In : Blood. 113, 8, p. 1749-1755 7 p.

Research output: Contribution to journalArticle

Myeloid Leukemia
Exons
Assays
Screening
Throughput
77 Citations (Scopus)

RNAi screen for rapid therapeutic target identification in leukemia patients

Tyner, J., Deininger, M. W., Loriaux, M., Chang, B., Gotli, J. R., Willis, S. G., Erickson, H., Kovacsovics, T., O'Hare, T., Heinrich, M. & Druker, B., May 26 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 21, p. 8695-8700 6 p.

Research output: Contribution to journalArticle

RNA Interference
Leukemia
Thrombopoietin Receptors
Genome
Technology
2010
79 Citations (Scopus)

A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic-phase chronic myeloid leukemia patients treated with imatinib

McWeeney, S., Pemberton, L. C., Loriaux, M., Vartanian, K., Willis, S. G., Yochum, G., Wilmot, B., Turpaz, Y., Pillai, R., Druker, B., Snead, J. L., MacPartlin, M., O'Brien, S. G., Melo, J. V., Lange, T., Harrington, C. C. & Deininger, M. W. N., Jan 14 2010, In : Blood. 115, 2, p. 315-325 11 p.

Research output: Contribution to journalArticle

Leukemia, Myeloid, Chronic Phase
Transcriptome
Gene expression
Cytogenetics
Classifiers
149 Citations (Scopus)

CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms

Tyner, J., Bumm, T. G., Deininger, J., Wood, L., Aichberger, K. J., Loriaux, M., Druker, B., Burns, C. J., Fantino, E. & Deininger, M. W., Jun 24 2010, In : Blood. 115, 25, p. 5232-5240 9 p.

Research output: Contribution to journalArticle

Janus Kinase 2
Cytokines
Neoplasms
TYK2 Kinase
Alleles
54 Citations (Scopus)

MET receptor sequence variants R970C and T992I lack transforming capacity

Tyner, J., Fletcher, L. B., Wang, E. Q., Yang, W. F., Rutenberg-Schoenberg, M. L., Beadling, C., Mori, M. T., Heinrich, M., Deininger, M. W., Druker, B. & Loriaux, M., Aug 1 2010, In : Cancer Research. 70, 15, p. 6233-6237 5 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Leukemia, Myelomonocytic, Chronic
Proto-Oncogene Proteins c-met
Mutation
Poisons

Small intestinal submucosa plug for closure of dilated nephrostomy tracts: A pilot study in swine

Kakizawa, H., Conlin, M., Pavcnik, D., Uchida, B., Loriaux, M., Kim, Y. H., Keller, F. & Rosch, J., Jun 2010, In : CardioVascular and Interventional Radiology. 33, 3, p. 596-600 5 p.

Research output: Contribution to journalArticle

Swine
Kidney
Foreign-Body Reaction
Urography
Infarction
1 Citation (Scopus)

Thrombus formation after percutaneous catheterization and manual compression of the femoral artery in heparinized sheep

Kim, Y. H., Pavcnik, D., Kakizawa, H., Uchida, B., Burke, A., Loriaux, M., Keller, F. & Rosch, J., Apr 2010, In : CardioVascular and Interventional Radiology. 33, 2, p. 321-329 9 p.

Research output: Contribution to journalArticle

Femoral Artery
Hemostasis
Catheterization
Sheep
Angiography
2011
7 Citations (Scopus)
Chromosome Aberrations
Chromosomes, Human, Pair 7
Cytogenetics
Mutation
Philadelphia Chromosome
501 Citations (Scopus)

CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

Lannutti, B. J., Meadows, S. A., Herman, S. E. M., Kashishian, A., Steiner, B., Johnson, A. J., Byrd, J. C., Tyner, J., Loriaux, M., Deininger, M., Druker, B., Puri, K. D., Ulrich, R. G. & Giese, N. A., Jan 13 2011, In : Blood. 117, 2, p. 591-594 4 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Phosphatidylinositol 3-Kinases
B-Lymphocytes
Cells
Neoplasms
459 Citations (Scopus)

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

Corbin, A. S., Agarwal, A., Loriaux, M., Cortes, J., Deininger, M. W. & Druker, B., Jan 4 2011, In : Journal of Clinical Investigation. 121, 1, p. 396-409 14 p.

Research output: Contribution to journalArticle

Myeloid Progenitor Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia
Therapeutics
Survival
1 Citation (Scopus)
Myeloid Progenitor Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Imatinib Mesylate
89 Citations (Scopus)

Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies

Gozgit, J. M., Wong, M. J., Wardwell, S., Tyner, J., Loriaux, M., Mohemmad, Q. K., Narasimhan, N. I., Shakespeare, W. C., Wang, F., Druker, B., Clackson, T. & Rivera, V. M., Jun 2011, In : Molecular Cancer Therapeutics. 10, 6, p. 1028-1035 8 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Acute Myeloid Leukemia
Receptor, Fibroblast Growth Factor, Type 1
Platelet-Derived Growth Factor Receptors
Inhibitory Concentration 50
35 Citations (Scopus)

Survey of activated FLT3 signaling in leukemia

Gu, T. L., Nardone, J., Wang, Y., Loriaux, M., Villén, J., Beausoleil, S., Tucker, M., Kornhauser, J., Ren, J., MacNeill, J., Gygi, S. P., Druker, B., Heinrich, M., Rush, J. & Polakiewicz, R. D., 2011, In : PLoS One. 6, 4, e19169.

Research output: Contribution to journalArticle

leukemia
Protein-Tyrosine Kinases
tyrosine
Leukemia
phosphotransferases (kinases)
111 Citations (Scopus)

TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms

Fleischman, A. G., Aichberger, K. J., Luty, S. B., Bumm, T. G., Petersen, C. L., Doratotaj, S., Vasudevan, K. B., LaTocha, D. H., Yang, F., Press, R., Loriaux, M., Pahl, H. L., Silver, R. T., Agarwal, A., O'Hare, T., Druker, B., Bagby, G. C. & Deininger, M. W., Dec 8 2011, In : Blood. 118, 24, p. 6392-6398 7 p.

Research output: Contribution to journalArticle

Cells
Stem cells
Stem Cells
Assays
Neoplasms
2012
9 Citations (Scopus)

An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma

Abraham, J., Chua, Y. X., Glover, J. M., Tyner, J., Loriaux, M., Kilcoyne, A., Giles, F. J., Nelon, L. D., Carew, J. S., Ouyang, Y., Michalek, J. E., Pal, R., Druker, B., Rubin, B. P. & Keller, C., Sep 28 2012, In : Biochemical and Biophysical Research Communications. 426, 3, p. 363-368 6 p.

Research output: Contribution to journalArticle

Alveolar Rhabdomyosarcoma
Rhabdomyosarcoma
Tumors
Cell culture
Primary Cell Culture
7 Citations (Scopus)

Creation of fibrinogen-enhanced experimental blood clots to evaluate mechanical thrombectomy devices for treatment of acute stroke: An in vitro study

Luo, Z. H., Chung, A., Choi, G., Lin, Y. H., Uchida, B., Pavcnik, D., Loriaux, M., Nesbit, G., Keller, F. & Rosch, J., Aug 2012, In : Journal of Vascular and Interventional Radiology. 23, 8, p. 1077-1083 7 p.

Research output: Contribution to journalArticle

Thrombectomy
Fibrinogen
Thrombosis
Stroke
Equipment and Supplies
94 Citations (Scopus)

Crosstalk between ROR1 and the Pre-B Cell Receptor Promotes Survival of t(1;19) Acute Lymphoblastic Leukemia

Bicocca, V. T., Chang, B., Masouleh, B. K., Muschen, M., Loriaux, M., Druker, B. & Tyner, J., Nov 13 2012, In : Cancer Cell. 22, 5, p. 656-667 12 p.

Research output: Contribution to journalArticle

Pre-B Cell Receptors
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Phosphorylation
Cell Surface Receptors
Phosphotransferases
26 Citations (Scopus)

Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML

Agarwal, A., Fleischman, A. G., Petersen, C. L., MacKenzie, R., Luty, S., Loriaux, M., Druker, B., Woltjer, R. R. & Deininger, M. W., Sep 27 2012, In : Blood. 120, 13, p. 2658-2668 11 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Phosphotransferases
Leukemia
Disease control
Stem cells
14 Citations (Scopus)
Gene Rearrangement
Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-Lymphoid Precursor Cells
Stem Cells
Therapeutics
14 Citations (Scopus)

Multiplex high-throughput gene mutation analysis in acute myeloid leukemia

Dunlap, J., Beadling, C., Warrick, A., Neff, T., Fleming, W., Loriaux, M., Heinrich, M., Kovacsovics, T., Kelemen, K., Leeborg, N., Gatter, K., Braziel, R., Press, R., Corless, C. & Fan, G., Dec 2012, In : Human Pathology. 43, 12, p. 2167-2176 10 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Mutation
Cytogenetics
Genes
Leukemia
41 Citations (Scopus)

Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia

Bains, T., Heinrich, M., Loriaux, M., Beadling, C., Nelson, D., Warrick, A., Neff, T. L., Tyner, J., Dunlap, J., Corless, C. & Fan, G., Sep 2012, In : Leukemia. 26, 9, p. 2144-2146 3 p.

Research output: Contribution to journalArticle

Janus Kinase 3
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Mutation
35 Citations (Scopus)

TSLP signaling network revealed by SILAC-based phosphoproteomics.

Zhong, J., Kim, M. S., Chaerkady, R., Wu, X., Huang, T. C., Getnet, D., Mitchell, C. J., Palapetta, S. M., Sharma, J., O'Meally, R. N., Cole, R. N., Yoda, A., Moritz, A., Loriaux, M., Rush, J., Weinstock, D. M., Tyner, J. & Pandey, A., Jun 2012, In : Molecular & cellular proteomics : MCP. 11, 6

Research output: Contribution to journalArticle

Isotope Labeling
thymic stromal lymphopoietin
Phosphorylation
src-Family Kinases
Cell culture
2013
14 Citations (Scopus)

A case study of personalized therapy for osteosarcoma

Davis, L., Hofmann, N. E., Li, G., Huang, E. T., Loriaux, M., Bracha, S., Helfand, S. C., Mata, J. E., Marley, K., Mansoor, A., Tyner, J., Abraham, J., Séguin, B. & Keller, C., Aug 2013, In : Pediatric Blood and Cancer. 60, 8, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

Osteosarcoma
Sarcoma
Canidae
Neoplasms
Therapeutics
4 Citations (Scopus)
Precision Medicine
Genes
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Small Interfering RNA
Genome