Marc Loriaux

Associate Professor

  • 5378 Citations
  • 33 h-Index
1991 …2020

Research output per year

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Research Output

  • 5378 Citations
  • 33 h-Index
  • 67 Article
  • 7 Letter
  • 1 Comment/debate
  • 1 Review article
2009

Functional characterization of an activating TEK mutation in acute myeloid leukemia: A cellular context-dependent activating mutation

Tyner, J. W., Rutenberg-Schoenberg, M. L., Erickson, H., Willis, S. G., O'Hare, T., Deininger, M. W., Druker, B. J. & Loriaux, M. M., Jan 1 2009, In : Leukemia. 23, 7, p. 1345-1348 4 p.

Research output: Contribution to journalLetter

4 Scopus citations

High-throughput mutational screen of the tyrosine kinome in chronic myelomonocytic leukemia

Tyner, J. W., Loriaux, M. M., Erickson, H., Eide, C. A., Deininger, J., MacPartlin, M., Willis, S. G., Lange, T., Druker, B. J., Kovacsovics, T., Maziarz, R., Gattermann, N. & Deininger, M. W., Jan 1 2009, In : Leukemia. 23, 2, p. 406-409 4 p.

Research output: Contribution to journalLetter

9 Scopus citations

High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

Tyner, J. W., Erickson, H., Deininger, M. W. N., Willis, S. G., Eide, C. A., Levine, R. L., Heinrich, M. C., Gattermann, N., Gilliland, D. G., Druker, B. J. & Loriaux, M. M., Feb 19 2009, In : Blood. 113, 8, p. 1749-1755 7 p.

Research output: Contribution to journalArticle

90 Scopus citations

RNAi screen for rapid therapeutic target identification in leukemia patients

Tyner, J. W., Deininger, M. W., Loriaux, M. M., Chang, B. H., Gotli, J. R., Willis, S. G., Erickson, H., Kovacsovics, T., O'Hare, T., Heinrich, M. C. & Druker, B. J., May 26 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 21, p. 8695-8700 6 p.

Research output: Contribution to journalArticle

79 Scopus citations
2008

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease

Agarwal, A., Bumm, T. G. P., Corbin, A. S., O'Hare, T., Loriaux, M., Van Dyke, J., Willis, S. G., Deininger, J., Nakayama, K. I., Druker, B. J. & Deininger, M. W., Sep 1 2008, In : Blood. 112, 5, p. 1960-1970 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

Loriaux, M. M., Levine, R. L., Tyner, J. W., Fröhling, S., Scholl, C., Stoffregen, E. P., Wernig, G., Erickson, H., Eide, C. A., Berger, R., Bernard, O. A., Griffin, J. D., Stone, R. M., Lee, B., Meyerson, M., Heinrich, M. C., Deininger, M. W., Gilliland, D. G. & Druker, B. J., May 1 2008, In : Blood. 111, 9, p. 4788-4796 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia

Tyner, J. W., Walters, D. K., Willis, S. G., Luttropp, M., Oost, J., Loriaux, M., Erickson, H., Corbin, A. S., O'Hare, T., Heinrich, M. C., Deininger, M. W. & Druker, B. J., Feb 15 2008, In : Blood. 111, 4, p. 2238-2245 8 p.

Research output: Contribution to journalArticle

57 Scopus citations
2007

Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles

Fröhling, S., Scholl, C., Levine, R. L., Loriaux, M., Boggon, T. J., Bernard, O. A., Berger, R., Döhner, H., Döhner, K., Ebert, B. L., Teckie, S., Golub, T. R., Jiang, J., Schittenhelm, M. M., Lee, B. H., Griffin, J. D., Stone, R. M., Heinrich, M. C., Deininger, M. W., Druker, B. J. & 1 others, Gilliland, D. G., Dec 6 2007, In : Cancer Cell. 12, 6, p. 501-513 13 p.

Research output: Contribution to journalArticle

133 Scopus citations
2006

Activating alleles of JAK3 in acute megakaryoblastic leukemia

Walters, D. K., Mercher, T., Gu, T. L., O'Hare, T., Tyner, J. W., Loriaux, M., Goss, V. L., Lee, K. A., Eide, C. A., Wong, M. J., Stoffregen, E. P., McGreevey, L., Nardone, J., Moore, S. A., Crispino, J., Boggon, T. J., Heinrich, M. C., Deininger, M. W., Polakiewicz, R. D., Gilliland, D. G. & 1 others, Druker, B. J., Jul 1 2006, In : Cancer Cell. 10, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

245 Scopus citations

Acute graft-versus-host disease of the heart

Roberts, S. S., Leeborg, N., Loriaux, M., Johnson, F. L., Huang, M. L., Stenzel, P., Thiede, C. & Godder, K. T., Oct 15 2006, In : Pediatric Blood and Cancer. 47, 5, p. 624-628 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Characterization of murine JAK2V617F-positive myeloproliferative disease

Bumm, T. G. P., Elsea, C., Corbin, A. S., Loriaux, M., Sherbenou, D., Wood, L., Deininger, J., Silver, R. T., Druker, B. J. & Deininger, M. W. N., Dec 1 2006, In : Cancer Research. 66, 23, p. 11156-11165 10 p.

Research output: Contribution to journalArticle

154 Scopus citations

Establishment of a murine model of aggressive systemic mastocytosis/mast cell leukemia

Demehri, S., Corbin, A., Loriaux, M., Druker, B. J. & Deininger, M. W., Mar 1 2006, In : Experimental hematology. 34, 3, p. 284-288 5 p.

Research output: Contribution to journalArticle

15 Scopus citations
2005

The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia

Levine, R. L., Loriaux, M., Huntly, B. J. P., Loh, M. L., Beran, M., Stoffregen, E., Berger, R., Clark, J. J., Willis, S. G., Nguyen, K. T., Flores, N. J., Estey, E., Gattermann, N., Armstrong, S., Look, A. T., Griffin, J. D., Bernard, O. A., Heinrich, M. C., Gilliland, D. G., Druker, B. & 1 others, Deininger, M. W. N., Nov 15 2005, In : Blood. 106, 10, p. 3377-3379 3 p.

Research output: Contribution to journalArticle

297 Scopus citations
2004

Clonal cytogenetic abnormalities in Philadelphia chromosome negative cells in chronic myeloid leukemia patients treated with imatinib

Loriaux, M. & Deininger, M., Nov 1 2004, In : Leukemia and Lymphoma. 45, 11, p. 2197-2203 7 p.

Research output: Contribution to journalReview article

62 Scopus citations

Fallopian tube occlusion with use of a small intestine submucosa device: Evaluation in a rabbit model

Binkert, C. A., Pavcnik, D., Andrews, R. T., Loriaux, M. M., Uchida, B., Brountzos, E. N. & Rösch, J., Jun 2004, In : Journal of Vascular and Interventional Radiology. 15, 6, p. 609-613 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Ph-positive and -negative myeloproliferative syndromes may co-exist [1]

Mauro, M. J., Loriaux, M. & Deininger, M. W., Jul 2004, In : Leukemia. 18, 7, p. 1305-1307 3 p.

Research output: Contribution to journalLetter

7 Scopus citations
2003

c-CBL is not required for leukemia induction by Bcr-Abl in mice

Dinulescu, D. M., Wood, L. J., Shen, L., Loriaux, M., Corless, C. L., Gross, A. W., Ren, R., Deininger, M. W. N. & Druker, B. J., Dec 4 2003, In : Oncogene. 22, 55, p. 8852-8860 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
100 Scopus citations
2002

Lack of suitability of the rabbit model for particulate uterine artery embolization

Binkert, C. A., Andrews, R. T., Pavcnik, D., Uchida, B., Loriaux, M. M., Toyota, N. & Rösch, J., Jan 1 2002, In : Journal of Vascular and Interventional Radiology. 13, 6, p. 609-612 4 p., 61655.

Research output: Contribution to journalArticle

4 Scopus citations
2001

Bifurcated drum occluder endograft for treatment of abdominal aortic aneurysm: An experimental study in dogs

Pavcnik, D., Uchida, B. T., Timmermans, H., Petersen, B., Loriaux, M., Yamakado, K., Voda, J., Yin, Q., Keller, F. S. & Rösch, J., Jan 1 2001, In : Journal of Vascular and Interventional Radiology. 12, 3, p. 359-364 6 p., 61917.

Research output: Contribution to journalArticle

7 Scopus citations
2000

The square stent-based large vessel occluder: An experimental pilot study

Pavcnik, D., Uchida, B. T., Timmermans, H., Corless, C. L., Loriaux, M., Keller, F. S. & Rosch, J., Jan 1 2000, In : Journal of Vascular and Interventional Radiology. 11, 9, p. 1227-1234 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
1999

Stent-grafts for de novo TIPS: Technique and early results

Andrews, R. T., Saxon, R. R., Bloch, R. D., Petersen, B. D., Uchida, B. T., Rabkin, J. M., Loriaux, M. M., Keller, F. S. & Rösch, J., Jan 1 1999, In : Journal of Vascular and Interventional Radiology. 10, 10, p. 1371-1378 8 p.

Research output: Contribution to journalArticle

52 Scopus citations
1998

Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine

Bloch, R., Pavcnik, D., Uchida, B. T., Krajina, A., Kamino, T., Timmermans, H., Loriaux, M. & Hulek, P., Nov 1 1998, In : Cardiovascular and interventional radiology. 21, 6, p. 497-500 4 p.

Research output: Contribution to journalArticle

25 Scopus citations
1994

Modulatory function of CREB·CREMα heterodimers depends upon CREMα phosphorylation

Loriaux, M. M., Brennan, R. G. & Goodman, R. H., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 28839-28843 5 p.

Research output: Contribution to journalArticle

32 Scopus citations
1993
Open Access
48 Scopus citations
1991

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A

Rehfuss, R. P., Walton, K. M., Loriaux, M. M. & Goodman, R. H., Nov 22 1991, In : Journal of Biological Chemistry. 266, 28, p. 18431-18434 4 p.

Research output: Contribution to journalArticle

172 Scopus citations