Marc Loriaux

Associate Professor

  • 4949 Citations
  • 32 h-Index
1991 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1991 2019

  • 4949 Citations
  • 32 h-Index
  • 73 Article
  • 1 Letter
2009
83 Citations (Scopus)

High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

Tyner, J., Erickson, H., Deininger, M. W. N., Willis, S. G., Eide, C. A., Levine, R. L., Heinrich, M., Gattermann, N., Gilliland, D. G., Druker, B. & Loriaux, M., Feb 19 2009, In : Blood. 113, 8, p. 1749-1755 7 p.

Research output: Contribution to journalArticle

Myeloid Leukemia
Exons
Assays
Screening
Throughput
77 Citations (Scopus)

RNAi screen for rapid therapeutic target identification in leukemia patients

Tyner, J., Deininger, M. W., Loriaux, M., Chang, B., Gotli, J. R., Willis, S. G., Erickson, H., Kovacsovics, T., O'Hare, T., Heinrich, M. & Druker, B., May 26 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 21, p. 8695-8700 6 p.

Research output: Contribution to journalArticle

RNA Interference
Leukemia
Thrombopoietin Receptors
Genome
Technology
2008
45 Citations (Scopus)

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease

Agarwal, A., Bumm, T. G. P., Corbin, A. S., O'Hare, T., Loriaux, M., Van Dyke, J., Willis, S. G., Deininger, J., Nakayama, K. I., Druker, B. & Deininger, M. W., Sep 1 2008, In : Blood. 112, 5, p. 1960-1970 11 p.

Research output: Contribution to journalArticle

S-Phase Kinase-Associated Proteins
Bone Marrow
Cells
F-Box Proteins
Transformed Cell Line
74 Citations (Scopus)

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

Loriaux, M., Levine, R. L., Tyner, J., Fröhling, S., Scholl, C., Stoffregen, E. P., Wernig, G., Erickson, H., Eide, C. A., Berger, R., Bernard, O. A., Griffin, J. D., Stone, R. M., Lee, B., Meyerson, M., Heinrich, M., Deininger, M. W., Gilliland, D. G. & Druker, B., May 1 2008, In : Blood. 111, 9, p. 4788-4796 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Sequence Analysis
Tyrosine
Alleles
57 Citations (Scopus)

RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia

Tyner, J., Walters, D. K., Willis, S. G., Luttropp, M., Oost, J., Loriaux, M., Erickson, H., Corbin, A. S., O'Hare, T., Heinrich, M., Deininger, M. W. & Druker, B., Feb 15 2008, In : Blood. 111, 4, p. 2238-2245 8 p.

Research output: Contribution to journalArticle

RNA Interference
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Tyrosine
Screening
2007
126 Citations (Scopus)

Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles

Fröhling, S., Scholl, C., Levine, R. L., Loriaux, M., Boggon, T. J., Bernard, O. A., Berger, R., Döhner, H., Döhner, K., Ebert, B. L., Teckie, S., Golub, T. R., Jiang, J., Schittenhelm, M. M., Lee, B. H., Griffin, J. D., Stone, R. M., Heinrich, M., Deininger, M. W., Druker, B. & 1 others, Gilliland, D. G., Dec 6 2007, In : Cancer Cell. 12, 6, p. 501-513 13 p.

Research output: Contribution to journalArticle

DNA Sequence Analysis
Alleles
Mutation
Phosphotransferases
Catalytic Domain
2006
240 Citations (Scopus)

Activating alleles of JAK3 in acute megakaryoblastic leukemia

Walters, D. K., Mercher, T., Gu, T. L., O'Hare, T., Tyner, J., Loriaux, M., Goss, V. L., Lee, K. A., Eide, C. A., Wong, M. J., Stoffregen, E. P., McGreevey, L., Nardone, J., Moore, S. A., Crispino, J., Boggon, T. J., Heinrich, M., Deininger, M. W., Polakiewicz, R. D., Gilliland, D. G. & 1 others, Druker, B., Jul 2006, In : Cancer Cell. 10, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Leukemia, Megakaryoblastic, Acute
Alleles
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Mutation
9 Citations (Scopus)

Acute graft-versus-host disease of the heart

Roberts, S. S., Leeborg, N., Loriaux, M., Johnson, F. L., Huang, M. L., Stenzel, P., Thiede, C. & Godder, K. T., Oct 15 2006, In : Pediatric Blood and Cancer. 47, 5, p. 624-628 5 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Bone Marrow Transplantation
Pediatrics
Chimerism
Gastrointestinal Tract
151 Citations (Scopus)

Characterization of murine JAK2V617F-positive myeloproliferative disease

Bumm, T. G. P., Elsea, C., Corbin, A. S., Loriaux, M., Sherbenou, D., Wood, L., Deininger, J., Silver, R. T., Druker, B. & Deininger, M. W. N., Dec 1 2006, In : Cancer Research. 66, 23, p. 11156-11165 10 p.

Research output: Contribution to journalArticle

Megakaryocyte-Erythroid Progenitor Cells
Myeloproliferative Disorders
Polycythemia Vera
Polycythemia
Primary Myelofibrosis
15 Citations (Scopus)

Establishment of a murine model of aggressive systemic mastocytosis/mast cell leukemia

Demehri, S., Corbin, A., Loriaux, M., Druker, B. & Deininger, M. W., Mar 2006, In : Experimental Hematology. 34, 3, p. 284-288 5 p.

Research output: Contribution to journalArticle

Mast-Cell Leukemia
Systemic Mastocytosis
Mastocytoma
Inbred DBA Mouse
Rare Diseases
2005
289 Citations (Scopus)

The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia

Levine, R. L., Loriaux, M., Huntly, B. J. P., Loh, M. L., Beran, M., Stoffregen, E., Berger, R., Clark, J. J., Willis, S. G., Nguyen, K. T., Flores, N. J., Estey, E., Gattermann, N., Armstrong, S., Look, A. T., Griffin, J. D., Bernard, O. A., Heinrich, M., Gilliland, D. G., Druker, B. & 1 others, Deininger, M. W. N., Nov 15 2005, In : Blood. 106, 10, p. 3377-3379 3 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
T-cells
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
2004
61 Citations (Scopus)

Clonal cytogenetic abnormalities in Philadelphia chromosome negative cells in chronic myeloid leukemia patients treated with imatinib

Loriaux, M. & Deininger, M., Nov 2004, In : Leukemia and Lymphoma. 45, 11, p. 2197-2203 7 p.

Research output: Contribution to journalArticle

Philadelphia Chromosome
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chromosome Aberrations
Clonal Evolution
Cytogenetics
5 Citations (Scopus)

Fallopian tube occlusion with use of a small intestine submucosa device: Evaluation in a rabbit model

Binkert, C. A., Pavcnik, D., Andrews, R. T., Loriaux, M., Uchida, B., Brountzos, E. N. & Rosch, J., Jun 2004, In : Journal of Vascular and Interventional Radiology. 15, 6, p. 609-613 5 p.

Research output: Contribution to journalArticle

Fallopian Tubes
Small Intestine
Rabbits
Equipment and Supplies
Hysterosalpingography
7 Citations (Scopus)

Ph-positive and -negative myeloproliferative syndromes may co-exist [1]

Mauro, M. J., Loriaux, M. & Deininger, M. W., Jul 2004, In : Leukemia. 18, 7, p. 1305-1307 3 p.

Research output: Contribution to journalArticle

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Bone Marrow Examination
Myeloproliferative Disorders
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Clone Cells
2003
13 Citations (Scopus)

c-CBL is not required for leukemia induction by Bcr-Abl in mice

Dinulescu, D. M., Wood, L., Shen, L., Loriaux, M., Corless, C., Gross, A. W., Ren, R., Deininger, M. W. N. & Druker, B., Dec 4 2003, In : Oncogene. 22, 55, p. 8852-8860 9 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-cbl
Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
bcr-abl Fusion Proteins
Cell Line
100 Citations (Scopus)
Philadelphia Chromosome
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cytogenetics
Clone Cells
Metaphase
2002
4 Citations (Scopus)

Lack of suitability of the rabbit model for particulate uterine artery embolization

Binkert, C. A., Andrews, R. T., Pavcnik, D., Uchida, B., Loriaux, M., Toyota, N. & Rosch, J., 2002, In : Journal of Vascular and Interventional Radiology. 13, 6, p. 609-612 4 p.

Research output: Contribution to journalArticle

Uterine Artery Embolization
Rabbits
Polyvinyl Alcohol
Uterine Artery
Pregnancy
2001
7 Citations (Scopus)

Bifurcated drum occluder endograft for treatment of abdominal aortic aneurysm: An experimental study in dogs

Pavcnik, D., Uchida, B., Timmermans, H., Petersen, B., Loriaux, M., Yamakado, K., Voda, J., Yin, Q. M., Keller, F. & Rosch, J., 2001, In : Journal of Vascular and Interventional Radiology. 12, 3, p. 359-364 6 p.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Dogs
Stents
Iliac Artery
Polytetrafluoroethylene
2000
15 Citations (Scopus)

The square stent-based large vessel occluder: An experimental pilot study

Pavcnik, D., Uchida, B., Timmermans, H., Corless, C., Loriaux, M., Keller, F. & Rosch, J., 2000, In : Journal of Vascular and Interventional Radiology. 11, 9, p. 1227-1234 8 p.

Research output: Contribution to journalArticle

Small Intestine
Stents
Angiography
Swine
Catheters
1999
52 Citations (Scopus)

Stent-grafts for de novo TIPS: Technique and early results

Andrews, R. T., Saxon, R. R., Bloch, R. D., Petersen, B., Uchida, B., Rabkin, J. M., Loriaux, M., Keller, F. & Rosch, J., 1999, In : Journal of Vascular and Interventional Radiology. 10, 10, p. 1371-1378 8 p.

Research output: Contribution to journalArticle

Transjugular Intrahepatic Portasystemic Shunt
Stents
Polytetrafluoroethylene
Transplants
Pathologic Constriction
1998
24 Citations (Scopus)

Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine

Bloch, R., Pavcnik, D., Uchida, B., Krajina, A., Kamino, T., Timmermans, H., Loriaux, M. & Hulek, P., Nov 1998, In : CardioVascular and Interventional Radiology. 21, 6, p. 497-500 4 p.

Research output: Contribution to journalArticle

Polyethylene Terephthalates
Polyurethanes
Transjugular Intrahepatic Portasystemic Shunt
Swine
Stents
1994
32 Citations (Scopus)

Modulatory function of CREB·CREMα heterodimers depends upon CREMα phosphorylation

Loriaux, M., Brennan, R. G. & Goodman, R., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 28839-28843 5 p.

Research output: Contribution to journalArticle

Phosphorylation
Cyclic AMP-Dependent Protein Kinases
Carrier Proteins
Chemical activation
Proteins
1993
47 Citations (Scopus)
Leucine Zippers
Phosphorylation
Basic-Leucine Zipper Transcription Factors
Transcriptional Activation
Proteins
1991
170 Citations (Scopus)

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A

Rehfuss, R. P., Walton, K. M., Loriaux, M. & Goodman, R., Oct 5 1991, In : Journal of Biological Chemistry. 266, 28, p. 18431-18434 4 p.

Research output: Contribution to journalArticle

Transcription
Cyclic AMP-Dependent Protein Kinases
Carrier Proteins
CREB-Binding Protein
Phosphorylation