Knight Cancer Institute

Research Output 1990 2019

Filter
Review article
2019
1 Citation (Scopus)

A systematic review of trial-level meta-analyses measuring the strength of association between surrogate end-points and overall survival in oncology

Haslam, A., Hey, S. P., Gill, J. & Prasad, V., Jan 1 2019, In : European Journal of Cancer. 106, p. 196-211 16 p.

Research output: Contribution to journalReview article

Meta-Analysis
Validation Studies
Biomarkers
Survival
Randomized Controlled Trials

Essere un medico conservativo

Mandrola, J., Cifu, A., Prasad, V. & Foy, A., Apr 1 2019, In : Recenti Progressi in Medicina. 110, 4, p. 156-158 3 p.

Research output: Contribution to journalReview article

Making adjuvant therapy decisions with uncertain data

Gyawali, B. & Prasad, V., Mar 1 2019, In : Annals of Oncology. 30, 3, p. 361-364 4 p.

Research output: Contribution to journalReview article

Open Access
Therapeutics

Real-world Evidence - What Does It Really Mean?

Nabhan, C., Klink, A. & Prasad, V., Jan 1 2019, In : JAMA Oncology.

Research output: Contribution to journalReview article

Relevance of Prognostic Factors in the Era of Targeted Therapies in CLL

Kittai, A. S., Lunning, M. & Danilov, A., Jan 1 2019, In : Current Hematologic Malignancy Reports.

Research output: Contribution to journalReview article

Biomarkers
Therapeutics
Phase III Clinical Trials
Chromosome Aberrations
Research
2018

Applicability of the AML knowledge bank approach

Borate, U., Aug 23 2018, In : Blood. 132, 8, p. 775-776 2 p.

Research output: Contribution to journalReview article

Chemotherapy
Tertiary Care Centers
Acute Myeloid Leukemia
Blood
Databases
25 Citations (Scopus)

CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought

Klein, M. E., Kovatcheva, M., Davis, L., Tap, W. D. & Koff, A., Jul 9 2018, In : Cancer Cell. 34, 1, p. 9-20 12 p.

Research output: Contribution to journalReview article

letrozole
Hormone Antagonists
Cytostatic Agents
Appointments and Schedules
Clinical Trials

Colorectal Lymphoma: A Review

Gay, N. D., Chen, A. & Okada, C., Jan 1 2018, In : Clinics in Colon and Rectal Surgery. 31, 5, p. 309-316 8 p.

Research output: Contribution to journalReview article

Non-Hodgkin's Lymphoma
Lymphoma
Colon
1 Citation (Scopus)

Current Practice Patterns Surrounding Fertility Concerns in Stage i Seminoma Patients: Survey of United States Radiation Oncologists

Post, C. M., Jain, A., Degnin, C., Chen, Y., Craycraft, M., Hung, A., Jaboin, J., Thomas, C. & Mitin, T., Jun 1 2018, In : Journal of Adolescent and Young Adult Oncology. 7, 3, p. 292-297 6 p.

Research output: Contribution to journalReview article

Seminoma
Fertility
Infertility
Radiotherapy
Observation
8 Citations (Scopus)

Direct-to-consumer genetic testing the implications of the US FDA's first marketing authorization for BRCA mutation testing

Gill, J., Obley, A. J. & Prasad, V., Jun 19 2018, In : JAMA - Journal of the American Medical Association. 319, 23, p. 2377-2378 2 p.

Research output: Contribution to journalReview article

Genetic Testing
Marketing
Mutation
Direct-To-Consumer Screening and Testing

Gonadotropin-releasing hormone antagonists in prostate cancer

Kittai, A. S., Blank, J. & Graff, J., Jan 1 2018, In : ONCOLOGY (United States). 32, 12, p. 599-606 8 p.

Research output: Contribution to journalReview article

Hormone Antagonists
Gonadotropin-Releasing Hormone
Prostatic Neoplasms
Castration
Androgens
2 Citations (Scopus)

Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy

Singer, J. W., Fleischman, A., Al-Fayoumi, S., Mascarenhas, J. O., Yu, Q. & Agarwal, A., Sep 1 2018, In : Oncotarget. 9, 70, p. 33416-33439 24 p.

Research output: Contribution to journalReview article

Interleukin-1 Receptor-Associated Kinases
Toll-Like Receptor 1
Protein-Serine-Threonine Kinases
Metabolic Diseases
Therapeutics
11 Citations (Scopus)

Osteosarcoma, chondrosarcoma, and chordoma

Whelan, J. S. & Davis, L., Jan 10 2018, In : Journal of Clinical Oncology. 36, 2, p. 188-193 6 p.

Research output: Contribution to journalReview article

Chordoma
Chondrosarcoma
Osteosarcoma
Sarcoma
Therapeutics
13 Citations (Scopus)

Pediatric-inspired treatment regimens for adolescents and young adults with philadelphia chromosome–negative acute lymphoblastic leukemia: A review

Siegel, S. E., Stock, W., Johnson, R. H., Advani, A., Muffly, L., Douer, D., Reed, D., Lewis, M., Freyer, D. R., Shah, B., Luger, S., Hayes-Lattin, B., Jaboin, J., Coccia, P. F., DeAngelo, D. J., Seibel, N. & Bleyer, A., May 1 2018, In : JAMA oncology. 4, 5, p. 725-734 10 p.

Research output: Contribution to journalReview article

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Young Adult
Pediatrics
Therapeutics
Clinical Trials

Studying the immune landscape in lung cancer models: Choosing the right experimental tools

Weeden, C. E., Ah-Cann, C. & Labat, M-L., Sep 1 2018, In : Translational Lung Cancer Research. 7, p. S248-S250

Research output: Contribution to journalReview article

Lung Neoplasms
1 Citation (Scopus)

The Role of Cruciferous Vegetables and Isothiocyanates for Lung Cancer Prevention: Current Status, Challenges, and Future Research Directions

Zhang, Z., Bergan, R., Shannon, J. J., Slatore, C. G., Bobe, G. & Takata, Y., Sep 1 2018, In : Molecular Nutrition and Food Research. 62, 18, 1700936.

Research output: Contribution to journalReview article

Isothiocyanates
isothiocyanates
lung neoplasms
Vegetables
Lung Neoplasms
2 Citations (Scopus)

Treatment of young adults with Philadelphia-negative acute lymphoblastic leukemia and lymphoblastic lymphoma: Hyper-CVAD vs. pediatric-inspired regimens

Siegel, S. E., Advani, A., Seibel, N., Muffly, L., Stock, W., Luger, S., Shah, B., DeAngelo, D. J., Freyer, D. R., Douer, D., Johnson, R. H., Hayes-Lattin, B., Lewis, M., Jaboin, J., Coccia, P. F. & Bleyer, A., Oct 1 2018, In : American Journal of Hematology. 93, 10, p. 1254-1266 13 p.

Research output: Contribution to journalReview article

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Young Adult
Pediatrics
T-Lymphoid Precursor Cells
Second Primary Neoplasms

Updates in the systemic treatment of hepatocellular carcinoma

Chen, E. Y., Lopez, C. & Vaccaro, G., Jan 1 2018, In : European Oncology and Haematology. 14, 2, p. 76-81 6 p.

Research output: Contribution to journalReview article

Hepatocellular Carcinoma
Phase III Clinical Trials
Pharmaceutical Preparations
Immunotherapy
Therapeutics
2017
3 Citations (Scopus)

A way forward for cancer chemoprevention: Think local

Rabadi, L. A. & Bergan, R., Jan 1 2017, In : Cancer Prevention Research. 10, 1, p. 14-35 22 p.

Research output: Contribution to journalReview article

Chemoprevention
Neoplasms
Carcinogenesis
Therapeutics
Organs at Risk
4 Citations (Scopus)

Bendamustine hydrochloride in patients with B-cell malignancies who have comorbidities–is there an optimal dose?

Gordon, M. J., Lewis, L. D., Brown, J. R. & Danilov, A., Aug 3 2017, In : Expert Review of Hematology. 10, 8, p. 707-718 12 p.

Research output: Contribution to journalReview article

B-Lymphocytes
Comorbidity
B-Cell Chronic Lymphocytic Leukemia
Neoplasms
Non-Hodgkin's Lymphoma
29 Citations (Scopus)

Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions

Zarour, L. R., Anand, S., Billingsley, K., Bisson, W. H., Cercek, A., Clarke, M. F., Coussens, L., Gast, C. E., Geltzeiler, C. B., Hansen, L., Kelley, K. A., Lopez, C., Rana, S. R., Ruhl, R., Tsikitis, V., Vaccaro, G., Wong, M. & Mayo, S., Mar 1 2017, In : CMGH Cellular and Molecular Gastroenterology and Hepatology. 3, 2, p. 163-173 11 p.

Research output: Contribution to journalReview article

Liver Neoplasms
Colorectal Neoplasms
Neoplasm Metastasis
Recurrence
Therapeutics

DNA distress creates lethal opportunity in MPN

Tyner, J., Dec 28 2017, In : Blood. 130, 26, p. 2814-2816 3 p.

Research output: Contribution to journalReview article

Stem Cells
Double-Stranded DNA Breaks
DNA
Stem cells
DNA Repair
14 Citations (Scopus)

Genomics of chronic neutrophilic leukemia

Maxson, J. & Tyner, J., Feb 9 2017, In : Blood. 129, 6, p. 715-722 8 p.

Research output: Contribution to journalReview article

Leukemia, Neutrophilic, Chronic
Colony-Stimulating Factors
Genomics
Mutation
Colony-Stimulating Factor Receptors
72 Citations (Scopus)

Guidelines for Validation of Next-Generation Sequencing–Based Oncology Panels: A Joint Consensus Recommendation of the Association for Molecular Pathology and College of American Pathologists

Jennings, L. J., Arcila, M. E., Corless, C., Kamel-Reid, S., Lubin, I. M., Pfeifer, J., Temple-Smolkin, R. L., Voelkerding, K. V. & Nikiforova, M. N., May 1 2017, In : Journal of Molecular Diagnostics. 19, 3, p. 341-365 25 p.

Research output: Contribution to journalReview article

Molecular Pathology
Joints
Guidelines
Practice Guidelines
Quality Control
24 Citations (Scopus)

Ibrutinib-associated bleeding: pathogenesis, management and risk reduction strategies

Shatzel, J. J., Olson, S. R., Tao, D. L., McCarty, O., Danilov, A. & Deloughery, T., May 1 2017, In : Journal of Thrombosis and Haemostasis. 15, 5, p. 835-847 13 p.

Research output: Contribution to journalReview article

Risk Reduction Behavior
Hemorrhage
Anticoagulants
PCI 32765
Lymphoproliferative Disorders
2 Citations (Scopus)

Kinase Inhibitor Screening in Myeloid Malignancies

Tyner, J., Aug 1 2017, In : Hematology/Oncology Clinics of North America. 31, 4, p. 693-704 12 p.

Research output: Contribution to journalReview article

Phosphotransferases
Neoplasms
Point Mutation
Pharmaceutical Preparations
Therapeutics
1 Citation (Scopus)

Myelodysplastic Syndromes: Updates and Nuances

Dao, K-H., Mar 1 2017, In : Medical Clinics of North America. 101, 2, p. 333-350 18 p.

Research output: Contribution to journalReview article

Myelodysplastic Syndromes
Bone Marrow
Genetic Markers
Stem Cells
Transplants
41 Citations (Scopus)

Prospective, randomized, double-blind, phase III clinical trial of anti-T-lymphocyte globulin to assess impact on chronic graft-versus-host disease-free survival in patients undergoing HLA-matched unrelated myeloablative hematopoietic cell transplantation

Soiffer, R. J., Kim, H. T., McGuirk, J., Horwitz, M. E., Johnston, L., Patnaik, M. M., Rybka, W., Artz, A., Porter, D. L., Shea, T. C., Boyer, M. W., Maziarz, R., Shaughnessy, P. J., Gergis, U., Safah, H., Reshef, R., Dipersio, J. F., Stiff, P. J., Vusirikala, M., Szer, J. & 12 othersHolter, J., Levine, J. D., Martin, P. J., Pidala, J. A., Lewis, I. D., Ho, V. T., Alyea, E. P., Ritz, J., Glavin, F., Westervelt, P., Jagasia, M. H. & Chen, Y. B., Dec 20 2017, In : Journal of Clinical Oncology. 35, 36, p. 4003-4011 9 p.

Research output: Contribution to journalReview article

Phase III Clinical Trials
Cell Transplantation
Graft vs Host Disease
Disease-Free Survival
T-Lymphocytes
8 Citations (Scopus)

Recommendations for clinical trial development in mantle cell lymphoma

Spurgeon, S., Till, B. G., Martin, P., Goy, A. H., Dreyling, M. P., Gopal, A. K., LeBlanc, M., Leonard, J. P., Friedberg, J. W., Baizer, L., Little, R. F., Kahl, B. S. & Smith, M. R., 2017, In : Journal of the National Cancer Institute. 109, 1, djw263.

Research output: Contribution to journalReview article

Mantle-Cell Lymphoma
Clinical Trials
Residual Neoplasm
Patient Outcome Assessment
Therapeutics
5 Citations (Scopus)

Stereotactic radiosurgery versus surgical resection for spinal hemangioblastoma: A systematic review

Bridges, K. J., Jaboin, J., Kubicky, C. D. & Than, K., Mar 1 2017, In : Clinical Neurology and Neurosurgery. 154, p. 59-66 8 p.

Research output: Contribution to journalReview article

Hemangioblastoma
Radiosurgery
Neoplasms
Spinal Cord
von Hippel-Lindau Disease
14 Citations (Scopus)

Syndromes of Thrombotic Microangiopathy

Shatzel, J. J. & Taylor, J., Mar 1 2017, In : Medical Clinics of North America. 101, 2, p. 395-415 21 p.

Research output: Contribution to journalReview article

Thrombotic Microangiopathies
Hemolytic-Uremic Syndrome
Purpura
Thrombocytopenia
Hemolysis
16 Citations (Scopus)

Turning the tide in myelodysplastic/myeloproliferative neoplasms

Deininger, M. W. N., Tyner, J. & Solary, E., Jul 1 2017, In : Nature Reviews Cancer. 17, 7, p. 425-440 16 p.

Research output: Contribution to journalReview article

Myelodysplastic Syndromes
Epigenomics
Genotype
Physiological Phenomena
Phenotype
7 Citations (Scopus)

Using molecular diagnostic testing to personalize the treatment of patients with gastrointestinal stromal tumors

Bannon, A. E., Klug, L. R., Corless, C. & Heinrich, M., May 4 2017, In : Expert Review of Molecular Diagnostics. 17, 5, p. 445-457 13 p.

Research output: Contribution to journalReview article

Molecular Diagnostic Techniques
Gastrointestinal Stromal Tumors
Molecular Pathology
Therapeutics
Decision Trees
2016
2 Citations (Scopus)

Conflict of interest in academic oncology: Moving beyond the blame game and forging a path forward

Prasad, V. & Rajkumar, S. V., Nov 4 2016, In : Blood Cancer Journal. 6, 11, e489.

Research output: Contribution to journalReview article

Conflict of Interest
3 Citations (Scopus)
Castration
Prostatic Neoplasms
Quality of Life
Placebos
Hot Flashes

JAKed up phenotype of CEBPA-mutant AML

Tyner, J., Jun 16 2016, In : Blood. 127, 24, p. 2946-2947 2 p.

Research output: Contribution to journalReview article

Data integration
Genetic Association Studies
Acute Myeloid Leukemia
Blood
Phenotype
3 Citations (Scopus)

Management of relapsed and refractory multiple myeloma in modern times: Incorporating new agents into decision-making

Clark, C. A., Cornell, R. F., Scott, E., Chung, J. & Costa, L. J., Oct 1 2016, In : American Journal of Hematology. 91, 10, p. 1044-1051 8 p.

Research output: Contribution to journalReview article

Multiple Myeloma
Decision Making
Proteasome Inhibitors
Therapeutics
Clone Cells
5 Citations (Scopus)

Treatment of Nonmetastatic Castration-Resistant Prostate Cancer

Luo, J., Beer, T. T. & Graff, J., Apr 1 2016, In : Oncology (Williston Park, N.Y.). 30, 4, p. 336-344 9 p.

Research output: Contribution to journalReview article

Castration
Prostatic Neoplasms
Disease Progression
Therapeutics
Clinical Trials
2015
14 Citations (Scopus)

Ibrutinib in mantle cell lymphoma patients: Glass half full? Evidence and opinion

Stephens, D. M. & Spurgeon, S., 2015, In : Therapeutic Advances in Hematology. 6, 5, p. 242-252 11 p.

Research output: Contribution to journalReview article

Mantle-Cell Lymphoma
Glass
Therapeutics
Recurrence
Residual Neoplasm
6 Citations (Scopus)

Reducing Skeletal-Related Events in Metastatic Castration-Resistant Prostate Cancer

Graff, J. & Beer, T. T., Jun 1 2015, In : Oncology (Williston Park, N.Y.). 29, 6, p. 416-423 8 p.

Research output: Contribution to journalReview article

zoledronic acid
Castration
Prostatic Neoplasms
Costs and Cost Analysis
Radium
2011
1 Citation (Scopus)

Rapid identification of therapeutic targets in hematologic malignancies via functional genomics

Tyner, J., 2011, In : Therapeutic Advances in Hematology. 2, 2, p. 83-93 11 p.

Research output: Contribution to journalReview article

Hematologic Neoplasms
Genomics
Genes
Pharmaceutical Preparations
Therapeutics
17 Citations (Scopus)

The cell giveth and the cell taketh away: An overview of Notch pathway activation by endocytic trafficking of ligands and receptors

Pratt, E. B., Wentzell, J. S., Maxson, J., Courter, L., Hazelett, D. & Christian, J. L., May 1 2011, In : Acta Histochemica. 113, 3, p. 248-255 8 p.

Research output: Contribution to journalReview article

Endocytosis
Ligands
Notch Receptors
Cell Surface Receptors
Cell Communication