Knight Cancer Institute

Research Output 1966 2019

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Comment/debate
2019
1 Citation (Scopus)

Cancer screening: A modest proposal for prevention

Kim, M. S., Nishikawa, G. & Prasad, V., Mar 1 2019, In : Cleveland Clinic journal of medicine. 86, 3, p. 157-160 4 p.

Research output: Contribution to journalComment/debate

Open Access
Early Detection of Cancer

Combining options in metastatic prostate cancer

Kopp, R. & Beer, T. T., Jan 1 2019, In : Nature Reviews Urology.

Research output: Contribution to journalComment/debate

Prostatic Neoplasms
docetaxel
Therapeutics

Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL (Oncotarget(2018) 9 (13023 -13035) DOI: 10.18632/oncotarget.24310)

Byrd, J. C., Smith, S., Wagner-Johnston, N., Sharman, J., Chen, A., Advani, R., Augustson, B., Marlton, P., Renee Commerford, S., Okrah, K., Liu, L., Murray, E., Penuel, E., Ward, A. F. & Flinn, I. W., Jan 1 2019, In : Oncotarget. 10, 38, p. 3827-3830 4 p.

Research output: Contribution to journalComment/debate

Open Access
B-Lymphocytes

Correction: Epigenetic therapy with panobinostat combined with bicalutamide rechallenge in castration-resistant prostate cancer (Clinical Cancer Research (2019) 25 (52-63) DOI: 10.1158/1078-0432.CCR-18-1589)

Ferrari, A. C., Alumkal, J., Stein, M. N., Taplin, M. E., Babb, J., Barnett, E. S., Gomez-Pinillos, A., Liu, X., Moore, D., DiPaola, R. & Beer, T. T., Apr 15 2019, In : Clinical Cancer Research. 25, 8, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Castration
Epigenomics
Prostatic Neoplasms
Emotions
Research

Correction: Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours (British Journal of Cancer, (2019), 120, 6, (612-620), 10.1038/s41416-019-0389-6)

Serrano, C., Mariño-Enríquez, A., Tao, D. L., Ketzer, J., Eilers, G., Zhu, M., Yu, C., Mannan, A. M., Rubin, B. P., Demetri, G. D., Raut, C. P., Presnell, A., McKinley, A., Heinrich, M., Czaplinski, J. T., Sicinska, E., Bauer, S., George, S. & Fletcher, J. A., Jan 1 2019, In : British Journal of Cancer.

Research output: Contribution to journalComment/debate

Open Access
Gastrointestinal Stromal Tumors
Expert Testimony
Protein-Tyrosine Kinases
Mutation
Pharmaceutical Preparations

Erratum: Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells (eLife (2019) 8 PII: e47174)

Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribeiro, R., Viola, S. K., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Mar 29 2019, In : eLife. 8

Research output: Contribution to journalComment/debate

Open Access
Exosomes
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Medicine
Bone

Erratum to: Interplay between hypoxia and androgen controls a metabolic switch conferring resistance to androgen/AR-targeted therapy (Nature Communications, (2018), 9, 1, (4972), 10.1038/s41467-018-07411-7)

Geng, H., Xue, C., Mendonca, J., Sun, X-X., Liu, Q., Reardon, P. N., Chen, Y., Qian, K., Hua, V., Chen, A., Pan, F., Yuan, J., Dang, S., Beer, T. T., Dai, M., Kachhap, S. K. & Qian, Z. D., Dec 1 2019, In : Nature Communications. 10, 1, 164.

Research output: Contribution to journalComment/debate

hypoxia
Androgens
therapy
switches
communication

Instilling value, quality, and safety through hematology and oncology stewardship

Chung, C., Kim, S. & Bubalo, J., Jan 1 2019, In : American Journal of Health-System Pharmacy. 76, 9, p. 617-621 5 p.

Research output: Contribution to journalComment/debate

Hematology
Safety

Registration studies — when should patients be deemed ineligible for aggressive therapy?

Cook, R. J., Gill, J. & Prasad, V., Jan 1 2019, In : Nature Reviews Clinical Oncology.

Research output: Contribution to journalComment/debate

Therapeutics

Testing for blinding in sham-controlled studies for procedural interventions: The third-party video method

Gill, J. & Prasad, V., Mar 11 2019, In : CMAJ. 191, 10, p. E272-E273

Research output: Contribution to journalComment/debate

2018
2 Citations (Scopus)

A novel AGGF1-PDGFRβ fusion in pediatric T-cell acute lymphoblastic leukemia

Zabriskie, M. S., Antelope, O., Verma, A. R., Draper, L. R., Eide, C. A., Pomicter, A. D., Tran, T. H., Druker, B., Tyner, J., Miles, R. R., Graham, J. M., Hwang, J. Y., Varley, K. E., Toydemir, R. M., Deininger, M. W., Raetz, E. A. & O’Hare, T., Jan 31 2018, In : Haematologica. 103, 2, p. e87-e91

Research output: Contribution to journalComment/debate

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
3 Citations (Scopus)

Choice of control group in randomised trials of cancer medicine: are we testing trivialities?

Tao, D. & Prasad, V., Sep 1 2018, In : The Lancet Oncology. 19, 9, p. 1150-1152 3 p.

Research output: Contribution to journalComment/debate

Medicine
Control Groups
Neoplasms

Competing immune biomarkers in the selection of first-line therapy in non-small cell lung cancer

Tolba, K., Jan 1 2018, In : European Oncology and Haematology. 14, 2, p. 67-69 3 p.

Research output: Contribution to journalComment/debate

Non-Small Cell Lung Carcinoma
Biomarkers
Therapeutics
pembrolizumab
3 Citations (Scopus)

Concerns about the approval of nusinersen sodium by the US food and drug administration

Gerrity, M. S., Prasad, V. & Obley, A. J., Jun 1 2018, In : JAMA Internal Medicine. 178, 6, p. 743-744 2 p.

Research output: Contribution to journalComment/debate

United States Food and Drug Administration
Sodium
2 Citations (Scopus)
Manuscripts
Neoplasms
Chromosomes
Uveal melanoma
14 Citations (Scopus)

Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

The MC3 Working Group & The Cancer Genome Atlas Research Network, Aug 9 2018, In : Cell. 174, 4, p. 1034-1035 2 p.

Research output: Contribution to journalComment/debate

Neoplasm Genes
Adenocarcinoma
Genes
Mutation
ethyl-2-methylthio-4-methyl-5-pyrimidine carboxylate
12 Citations (Scopus)
Urinary Bladder Neoplasms
Names
Muscle
Muscles
8 Citations (Scopus)

Erratum: The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (Cell Reports (2018) 23(1) (313–326.e5) (S2211124718304364) (10.1016/j.celrep.2018.03.075))

The Cancer Genome Atlas Research Network & The Cancer Genome Atlas Research Network, Jun 19 2018, In : Cell Reports. 23, 12, 1 p.

Research output: Contribution to journalComment/debate

Atlases
Renal Cell Carcinoma
Names
Emotions
Genes
2 Citations (Scopus)

Erratum: Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (Cell (2018) 174(3) (758–769.e9), (S0092867418308420) (10.1016/j.cell.2018.06.039))

Quigley, D. A., Dang, H. X., Zhao, S. G., Lloyd, P., Aggarwal, R., Alumkal, J., Foye, A., Kothari, V., Perry, M. D., Bailey, A. M., Playdle, D., Barnard, T. J., Zhang, L., Zhang, J., Youngren, J. F., Cieslik, M. P., Parolia, A., Beer, T. T., Thomas, G., Chi, K. N. & 43 others, Gleave, M., Lack, N. A., Zoubeidi, A., Reiter, R. E., Rettig, M. B., Witte, O., Ryan, C. J., Fong, L., Kim, W., Friedlander, T., Chou, J., Li, H., Das, R., Li, H., Moussavi-Baygi, R., Goodarzi, H., Gilbert, L. A., Lara, P. N., Evans, C. P., Goldstein, T. C., Stuart, J. M., Tomlins, S. A., Spratt, D. E., Cheetham, R. K., Cheng, D. T., Farh, K., Gehring, J. S., Hakenberg, J., Liao, A., Febbo, P. G., Shon, J., Sickler, B., Batzoglou, S., Knudsen, K. E., He, H. H., Huang, J., Wyatt, A. W., Dehm, S. M., Ashworth, A., Chinnaiyan, A. M., Maher, C. A., Small, E. J. & Feng, F. Y., Oct 18 2018, In : Cell. 175, 3, 1 p.

Research output: Contribution to journalComment/debate

Genomic Structural Variation
Manuscripts
Amplification
Prostatic Neoplasms
Statistical tests
Names
Genome
Guidelines
RNA
5 Citations (Scopus)

Improving observational studies in the era of big data

Gill, J. & Prasad, V., Sep 1 2018, In : The Lancet. 392, 10149, p. 716-717 2 p.

Research output: Contribution to journalComment/debate

Observational Studies
5 Citations (Scopus)

Pemetrexed in nonsquamous non-small-cell lung cancer: The billion dollar subgroup analysis

Gyawali, B. & Prasad, V., Jan 1 2018, In : JAMA oncology. 4, 1, p. 17-18 2 p.

Research output: Contribution to journalComment/debate

Pemetrexed
Non-Small Cell Lung Carcinoma

Review: In VTE, reduced- and full-dose extended DOAC therapies do not differ and are better than no extended therapy

Vasanthamohan, L. & Deloughery, T., Nov 20 2018, In : Annals of Internal Medicine. 169, 10, p. JC52

Research output: Contribution to journalComment/debate

Therapeutics
37 Citations (Scopus)

Tisagenlecleucel - The first approved CAR-T-cell therapy: Implications for payers and policy makers

Prasad, V., Jan 1 2018, In : Nature Reviews Clinical Oncology. 15, 1, p. 11-12 2 p.

Research output: Contribution to journalComment/debate

Cell- and Tissue-Based Therapy
Administrative Personnel
T-Lymphocytes
2017

Academic cancer center phase i program development

Frankel, A. E., Flaherty, K. T., Weiner, G. J., Chen, R., Azad, N. S., Pishvaian, M. J., Thompson, J. A., Taylor, M., Mahadevan, D., Lockhart, A. C., Vaishampayan, U. N., Berlin, J. D., Smith, D. C., Sarantopoulos, J., Riese, M., Saleh, M. N., Ahn, C. & Frenkel, E. P., Apr 1 2017, In : Oncologist. 22, 4, p. 369-374 6 p.

Research output: Contribution to journalComment/debate

Program Development
Neoplasms
Research
Research Personnel
Clinical Trials
2 Citations (Scopus)

Can Neutropenic Fever Ever Be Low Risk?

Paddock, M., Grock, A., Deloughery, T. & Mason, J., Jun 1 2017, In : Annals of Emergency Medicine. 69, 6, p. 765-767 3 p.

Research output: Contribution to journalComment/debate

Fever
12 Citations (Scopus)

Clinical trial enrollment of adolescents and young adults with sarcoma

Davis, L., Janeway, K. A., Weiss, A. R., Chen, Y. L. E., Scharschmidt, T. J., Krailo, M., Glade Bender, J. L., Kopp, L. M., Patel, S. R., Schwartz, G. K., Horvath, L. E., Hawkins, D. S., Chuk, M. K., Reinke, D. K., Gorlick, R. G. & Randall, R. L., Sep 15 2017, In : Cancer. 123, 18, p. 3434-3440 7 p.

Research output: Contribution to journalComment/debate

Sarcoma
Young Adult
Clinical Trials
Publications
Neoplasms

Commentary

Deloughery, T., Feb 21 2017, In : Annals of Internal Medicine. 166, 4, p. JC15

Research output: Contribution to journalComment/debate

6 Citations (Scopus)

Drugs that lack single-agent activity: Are they worth pursuing in combination?

Gyawali, B. & Prasad, V., Apr 1 2017, In : Nature Reviews Clinical Oncology. 14, 4, p. 193-194 2 p.

Research output: Contribution to journalComment/debate

Pharmaceutical Preparations
3 Citations (Scopus)

Pembrolizumab as first-line therapy in programmed death ligand 1–positive advanced lung cancer: Is it as effective as we think it is?

Goldstein, D. A., Bilal, U. & Prasad, V., Oct 15 2017, In : Cancer. 123, 20, p. 3872-3874 3 p.

Research output: Contribution to journalComment/debate

Lung Neoplasms
Ligands
Therapeutics
pembrolizumab
2016
26 Citations (Scopus)

Consensus Opinion on Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis

Ustun, C., Gotlib, J., Popat, U., Artz, A., Litzow, M., Reiter, A., Nakamura, R., Kluin-Nelemans, H. C., Verstovsek, S., Gajewski, J., Perales, M. A., George, T., Shore, T., Sperr, W., Saber, W., Kota, V., Yavuz, A. S., Pullarkat, V., Rogosheske, J., Hogan, W. & 11 others, Van Besien, K., Hagglund, H., Damaj, G., Arock, M., Horny, H. P., Metcalfe, D. D., Deeg, H. J., Devine, S., Weisdorf, D., Akin, C. & Valent, P., Aug 1 2016, In : Biology of Blood and Marrow Transplantation. 22, 8, p. 1348-1356 9 p.

Research output: Contribution to journalComment/debate

Systemic Mastocytosis
Cell Transplantation
1 Citation (Scopus)

Cover Image, Volume 171B, Number 6, September 2016

IMAGE2 Consortium & German ADHD GWAS Group, Sep 1 2016, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 171, 6, p. 1 1 p.

Research output: Contribution to journalComment/debate

Erratum: A new era for hemophilia B treatment (Blood (2016) 127:14 (1734-1736))

Taylor, J. & Kruse-Jarres, R., Oct 13 2016, In : Blood. 128, 15, p. 1994 1 p.

Research output: Contribution to journalComment/debate

Hemophilia B
Blood
96 Citations (Scopus)

Perspective: The precision-oncology illusion

Prasad, V., Sep 7 2016, In : Nature. 537, 7619, p. S63

Research output: Contribution to journalComment/debate

Molecular Targeted Therapy
Precision Medicine
Medical Oncology
Genetic Testing
Reproducibility of Results

Precision medicine in diffuse large B-cell lymphoma: Hype or hope?

Prasad, V., Nov 1 2016, In : European Journal of Cancer. 68, p. 22-26 5 p.

Research output: Contribution to journalComment/debate

Precision Medicine
Lymphoma, Large B-Cell, Diffuse
3 Citations (Scopus)

Same data; Different interpretations

Bishal Gyawali, G. & Prasad, V., Nov 1 2016, In : Journal of Clinical Oncology. 34, 31, p. 3729-3732 4 p.

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Thinking systematically about the off-label use of cancer drugs and combinations for patientswho have exhausted proven therapies

Mailankody, S. & Prasad, V., Sep 1 2016, In : Oncologist. 21, 9, p. 1031-1032 2 p.

Research output: Contribution to journalComment/debate

Off-Label Use
Drug Combinations
Neoplasms
Therapeutics