Knight Cancer Institute

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2020

Our best weapons against cancer are not magic bullets

Prasad, V., Jan 23 2020, In : Nature. 577, 7791, 1 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Replacing the NCCN’s Blocks with Wheels: How Should Consideration of Societal Spending be Incorporated into Oncology Practice?

Tran, A. A. & Prasad, V., Jan 1 2020, (Accepted/In press) In : PharmacoEconomics.

Research output: Contribution to journalComment/debate

2019

A reality check of the accelerated approval of immune-checkpoint inhibitors

Gill, J. & Prasad, V., Jan 1 2019, (Accepted/In press) In : Nature Reviews Clinical Oncology.

Research output: Contribution to journalComment/debate

3 Scopus citations

Cancer screening: A modest proposal for prevention

Kim, M. S., Nishikawa, G. & Prasad, V., Mar 1 2019, In : Cleveland Clinic journal of medicine. 86, 3, p. 157-160 4 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Cells tagged near an early spread of cancer

Labat, M-L., Aug 1 2019, In : Nature. 572, 7771, p. 589-590 2 p.

Research output: Contribution to journalComment/debate

Open Access

Combining options in metastatic prostate cancer

Kopp, R. & Beer, T. T., Jan 1 2019, In : Nature Reviews Urology.

Research output: Contribution to journalComment/debate

Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL (Oncotarget(2018) 9 (13023 -13035) DOI: 10.18632/oncotarget.24310)

Byrd, J. C., Smith, S., Wagner-Johnston, N., Sharman, J., Chen, A. I., Advani, R., Augustson, B., Marlton, P., Renee Commerford, S., Okrah, K., Liu, L., Murray, E., Penuel, E., Ward, A. F. & Flinn, I. W., Jan 1 2019, In : Oncotarget. 10, 38, p. 3827-3830 4 p.

Research output: Contribution to journalComment/debate

Open Access

Correction: Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer (Oncogene, (2017), 36, 12, (1745-1752), 10.1038/onc.2016.327)

Kang, M. H., Jeong, K. J., Kim, W. Y., Lee, H. J., Gong, G., Suh, N., Győrffy, B., Kim, S., Jeong, S. Y., Mills, G. B. & Park, Y. Y., May 30 2019, In : Oncogene. 38, 22, p. 4427-4428 2 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Correction: A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory (Oncotarget (2017) 8 (41806-41814) DOI: 10.18632/oncotarget.16018

Arango, N. P., Brusco, L., Shaw, K. R. M., Chen, K., Eterovic, A. K., Holla, V., Johnson, A., Litzenburger, B., Khotskaya, Y. B., Sanchez, N., Bailey, A., Zheng, X., Horombe, C., Kopetz, S., Farhangfar, C. J., Routbort, M., Broaddus, R., Bernstam, E. V., Mendelsohn, J., Mills, G. B. & 1 others, Meric-Bernstam, F., Jan 1 2019, In : Oncotarget. 10, 50, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Correction: Epigenetic therapy with panobinostat combined with bicalutamide rechallenge in castration-resistant prostate cancer (Clinical Cancer Research (2019) 25 (52-63) DOI: 10.1158/1078-0432.CCR-18-1589)

Ferrari, A. C., Alumkal, J. J., Stein, M. N., Taplin, M. E., Babb, J., Barnett, E. S., Gomez-Pinillos, A., Liu, X., Moore, D., DiPaola, R. & Beer, T. M., Apr 15 2019, In : Clinical Cancer Research. 25, 8, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Correction: Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours (British Journal of Cancer, (2019), 120, 6, (612-620), 10.1038/s41416-019-0389-6)

Serrano, C., Mariño-Enríquez, A., Tao, D. L., Ketzer, J., Eilers, G., Zhu, M., Yu, C., Mannan, A. M., Rubin, B. P., Demetri, G. D., Raut, C. P., Presnell, A., McKinley, A., Heinrich, M. C., Czaplinski, J. T., Sicinska, E., Bauer, S., George, S. & Fletcher, J. A., Jul 30 2019, In : British Journal of Cancer. 121, 3, 1 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Erratum: Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells (eLife (2019) 8 PII: e47174)

Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribeiro, R., Viola, S. K., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J. W., Druker, B. J. & Traer, E., Mar 29 2019, In : eLife. 8

Research output: Contribution to journalComment/debate

Open Access

Erratum to: PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas (Nature, (2017), 10.1038/nature24040)

Lu, H., Liu, S., Zhang, G., Wu, B., Zhu, Y., Frederick, D. T., Hu, Y., Zhong, W., Randell, S., Sadek, N., Zhang, W., Chen, G., Cheng, C., Zeng, J., Wu, L. W., Zhang, J., Liu, X., Xu, W., Krepler, C., Sproesser, K. & 21 others, Xiao, M., Miao, B., Liu, J., Song, C. D., Liu, J. Y., Karakousis, G. C., Schuchter, L. M., Lu, Y., Mills, G., Cong, Y., Chernoff, J., Guo, J., Boland, G. M., Sullivan, R. J., Wei, Z., Field, J., Amaravadi, R. K., Flaherty, K. T., Herlyn, M., Xu, X. & Guo, W., Jan 10 2019, In : Nature. 565, 7738, p. E4

Research output: Contribution to journalComment/debate

Erratum to: Interplay between hypoxia and androgen controls a metabolic switch conferring resistance to androgen/AR-targeted therapy (Nature Communications, (2018), 9, 1, (4972), 10.1038/s41467-018-07411-7)

Geng, H., Xue, C., Mendonca, J., Sun, X. X., Liu, Q., Reardon, P. N., Chen, Y., Qian, K., Hua, V., Chen, A., Pan, F., Yuan, J., Dang, S., Beer, T. M., Dai, M. S., Kachhap, S. K. & Qian, D. Z., Dec 1 2019, In : Nature communications. 10, 1, 164.

Research output: Contribution to journalComment/debate

Guideline: EULAR provided recommendations for thrombotic and obstetric antiphospholipid syndrome

Tektonidou, M. G., Andreoli, L., Limper, M., Tincani, A., Ward, M. M. & DeLoughery, T., Sep 17 2019, In : Annals of internal medicine. 171, 6, p. JC26

Research output: Contribution to journalComment/debate

Instilling value, quality, and safety through hematology and oncology stewardship

Chung, C., Kim, S. & Bubalo, J., Jan 1 2019, In : American Journal of Health-System Pharmacy. 76, 9, p. 617-621 5 p.

Research output: Contribution to journalComment/debate

Multiplicity in oncology randomised controlled trials: a threat to medical evidence?

Prasad, V. & Booth, C. M., Dec 2019, In : The Lancet Oncology. 20, 12, p. 1638-1640 3 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Recipe for a Graft: T Cell Dose Remains Elusive

Maziarz, R. T. & Cook, R. J., Sep 2019, In : Biology of Blood and Marrow Transplantation. 25, 9, p. e275-e276

Research output: Contribution to journalComment/debate

Registration studies — when should patients be deemed ineligible for aggressive therapy?

Cook, R. J., Gill, J. & Prasad, V., Jan 1 2019, In : Nature Reviews Clinical Oncology.

Research output: Contribution to journalComment/debate

1 Scopus citations

Should Evidence Come with an Expiration Date?

Greene, P., Prasad, V. & Cifu, A., Jul 15 2019, In : Journal of general internal medicine. 34, 7, p. 1356-1357 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Testing for blinding in sham-controlled studies for procedural interventions: The third-party video method

Gill, J. & Prasad, V., Mar 11 2019, In : CMAJ. 191, 10, p. E272-E273

Research output: Contribution to journalComment/debate

2018

A novel AGGF1-PDGFRβ fusion in pediatric T-cell acute lymphoblastic leukemia

Zabriskie, M. S., Antelope, O., Verma, A. R., Draper, L. R., Eide, C. A., Pomicter, A. D., Tran, T. H., Druker, B., Tyner, J., Miles, R. R., Graham, J. M., Hwang, J. Y., Varley, K. E., Toydemir, R. M., Deininger, M. W., Raetz, E. A. & O’Hare, T., Jan 31 2018, In : Haematologica. 103, 2, p. e87-e91

Research output: Contribution to journalComment/debate

4 Scopus citations

Choice of control group in randomised trials of cancer medicine: are we testing trivialities?

Tao, D. & Prasad, V., Sep 1 2018, In : The Lancet Oncology. 19, 9, p. 1150-1152 3 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

Competing immune biomarkers in the selection of first-line therapy in non-small cell lung cancer

Tolba, K., Jan 1 2018, In : European Oncology and Haematology. 14, 2, p. 67-69 3 p.

Research output: Contribution to journalComment/debate

Concerns about the approval of nusinersen sodium by the US food and drug administration

Gerrity, M. S., Prasad, V. & Obley, A. J., Jun 1 2018, In : JAMA Internal Medicine. 178, 6, p. 743-744 2 p.

Research output: Contribution to journalComment/debate

5 Scopus citations
14 Scopus citations

Erratum: Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (Cell (2018) 174(3) (758–769.e9), (S0092867418308420) (10.1016/j.cell.2018.06.039))

Quigley, D. A., Dang, H. X., Zhao, S. G., Lloyd, P., Aggarwal, R., Alumkal, J. J., Foye, A., Kothari, V., Perry, M. D., Bailey, A. M., Playdle, D., Barnard, T. J., Zhang, L., Zhang, J., Youngren, J. F., Cieslik, M. P., Parolia, A., Beer, T. M., Thomas, G., Chi, K. N. & 43 others, Gleave, M., Lack, N. A., Zoubeidi, A., Reiter, R. E., Rettig, M. B., Witte, O., Ryan, C. J., Fong, L., Kim, W., Friedlander, T., Chou, J., Li, H., Das, R., Li, H., Moussavi-Baygi, R., Goodarzi, H., Gilbert, L. A., Lara, P. N., Evans, C. P., Goldstein, T. C., Stuart, J. M., Tomlins, S. A., Spratt, D. E., Cheetham, R. K., Cheng, D. T., Farh, K., Gehring, J. S., Hakenberg, J., Liao, A., Febbo, P. G., Shon, J., Sickler, B., Batzoglou, S., Knudsen, K. E., He, H. H., Huang, J., Wyatt, A. W., Dehm, S. M., Ashworth, A., Chinnaiyan, A. M., Maher, C. A., Small, E. J. & Feng, F. Y., Oct 18 2018, In : Cell. 175, 3, 1 p.

Research output: Contribution to journalComment/debate

7 Scopus citations

Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

The MC3 Working Group & The Cancer Genome Atlas Research Network, Aug 9 2018, In : Cell. 174, 4, p. 1034-1035 2 p.

Research output: Contribution to journalComment/debate

50 Scopus citations
24 Scopus citations
36 Scopus citations

Erratum to: Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study (Nature Methods, (2018), 15, 9, (669-676), 10.1038/s41592-018-0085-0)

Hellenkamp, B., Schmid, S., Doroshenko, O., Opanasyuk, O., Kühnemuth, R., Adariani, S. R., Ambrose, B., Aznauryan, M., Barth, A., Birkedal, V., Bowen, M. E., Chen, H., Cordes, T., Eilert, T., Fijen, C., Gebhardt, C., Götz, M., Gouridis, G., Gratton, E., Ha, T. & 43 others, Hao, P., Hanke, C. A., Hartmann, A., Hendrix, J., Hildebrandt, L. L., Hirschfeld, V., Hohlbein, J., Hua, B., Hübner, C. G., Kallis, E., Kapanidis, A. N., Kim, J. Y., Krainer, G., Lamb, D. C., Lee, N. K., Lemke, E. A., Levesque, B., Levitus, M., McCann, J. J., Naredi-Rainer, N., Nettels, D., Ngo, T., Qiu, R., Robb, N. C., Röcker, C., Sanabria, H., Schlierf, M., Schröder, T., Schuler, B., Seidel, H., Streit, L., Thurn, J., Tinnefeld, P., Tyagi, S., Vandenberk, N., Vera, A. M., Weninger, K. R., Wünsch, B., Yanez-Orozco, I. S., Michaelis, J., Seidel, C. A. M., Craggs, T. D. & Hugel, T., Nov 1 2018, In : Nature Methods. 15, 11, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Improving observational studies in the era of big data

Gill, J. & Prasad, V., Sep 1 2018, In : The Lancet. 392, 10149, p. 716-717 2 p.

Research output: Contribution to journalComment/debate

11 Scopus citations

Pemetrexed in nonsquamous non-small-cell lung cancer: The billion dollar subgroup analysis

Gyawali, B. & Prasad, V., Jan 2018, In : JAMA Oncology. 4, 1, p. 17-18 2 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Review: In VTE, reduced- and full-dose extended DOAC therapies do not differ and are better than no extended therapy

Vasanthamohan, L. & Deloughery, T., Nov 20 2018, In : Annals of Internal Medicine. 169, 10, p. JC52

Research output: Contribution to journalComment/debate

Tisagenlecleucel - The first approved CAR-T-cell therapy: Implications for payers and policy makers

Prasad, V., Jan 1 2018, In : Nature Reviews Clinical Oncology. 15, 1, p. 11-12 2 p.

Research output: Contribution to journalComment/debate

51 Scopus citations
2017

Academic cancer center phase i program development

Frankel, A. E., Flaherty, K. T., Weiner, G. J., Chen, R., Azad, N. S., Pishvaian, M. J., Thompson, J. A., Taylor, M. H., Mahadevan, D., Lockhart, A. C., Vaishampayan, U. N., Berlin, J. D., Smith, D. C., Sarantopoulos, J., Riese, M., Saleh, M. N., Ahn, C. & Frenkel, E. P., Apr 2017, In : Oncologist. 22, 4, p. 369-374 6 p.

Research output: Contribution to journalComment/debate

Can Neutropenic Fever Ever Be Low Risk?

Paddock, M., Grock, A., Deloughery, T. & Mason, J., Jun 1 2017, In : Annals of Emergency Medicine. 69, 6, p. 765-767 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Clinical trial enrollment of adolescents and young adults with sarcoma

Davis, L. E., Janeway, K. A., Weiss, A. R., Chen, Y. L. E., Scharschmidt, T. J., Krailo, M., Glade Bender, J. L., Kopp, L. M., Patel, S. R., Schwartz, G. K., Horvath, L. E., Hawkins, D. S., Chuk, M. K., Reinke, D. K., Gorlick, R. G. & Randall, R. L., Sep 15 2017, In : Cancer. 123, 18, p. 3434-3440 7 p.

Research output: Contribution to journalComment/debate

14 Scopus citations

Commentary

Deloughery, T., Feb 21 2017, In : Annals of Internal Medicine. 166, 4, p. JC15

Research output: Contribution to journalComment/debate

Drugs that lack single-agent activity: Are they worth pursuing in combination?

Gyawali, B. & Prasad, V., Apr 1 2017, In : Nature Reviews Clinical Oncology. 14, 4, p. 193-194 2 p.

Research output: Contribution to journalComment/debate

8 Scopus citations
40 Scopus citations

Pembrolizumab as first-line therapy in programmed death ligand 1–positive advanced lung cancer: Is it as effective as we think it is?

Goldstein, D. A., Bilal, U. & Prasad, V., Oct 15 2017, In : Cancer. 123, 20, p. 3872-3874 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
2016

Consensus Opinion on Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis

Ustun, C., Gotlib, J., Popat, U., Artz, A., Litzow, M., Reiter, A., Nakamura, R., Kluin-Nelemans, H. C., Verstovsek, S., Gajewski, J., Perales, M. A., George, T., Shore, T., Sperr, W., Saber, W., Kota, V., Yavuz, A. S., Pullarkat, V., Rogosheske, J., Hogan, W. & 11 others, Van Besien, K., Hagglund, H., Damaj, G., Arock, M., Horny, H. P., Metcalfe, D. D., Deeg, H. J., Devine, S., Weisdorf, D., Akin, C. & Valent, P., Aug 1 2016, In : Biology of Blood and Marrow Transplantation. 22, 8, p. 1348-1356 9 p.

Research output: Contribution to journalComment/debate

34 Scopus citations

Cover Image, Volume 171B, Number 6, September 2016

IMAGE2 Consortium & German ADHD GWAS Group, Sep 1 2016, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 171, 6, p. 1 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Erratum: Risk factors and impact of non-Aspergillus mold infections following allogeneic HCT: A CIBMTR infection and immune reconstitution analysis (Bone Marrow Transplantation (2016) 51 (277-282) DOI:10.1038/bmt.2015.263)

Riches, M. L., Trifilio, S., Chen, M., Ahn, K. W., Langston, A., Lazarus, H. M., Marks, D. I., Martino, R., Maziarz, R. T., Papanicolou, G. A., Wingard, J. R., Young, J. A. & Bennett, C. L., Feb 1 2016, In : Bone marrow transplantation. 51, 2, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum: A new era for hemophilia B treatment (Blood (2016) 127:14 (1734-1736))

Taylor, J. & Kruse-Jarres, R., Oct 13 2016, In : Blood. 128, 15, p. 1994 1 p.

Research output: Contribution to journalComment/debate

Perspective: The precision-oncology illusion

Prasad, V., Sep 7 2016, In : Nature. 537, 7619, p. S63

Research output: Contribution to journalComment/debate

121 Scopus citations

Precision medicine in diffuse large B-cell lymphoma: Hype or hope?

Prasad, V., Nov 1 2016, In : European Journal of Cancer. 68, p. 22-26 5 p.

Research output: Contribution to journalComment/debate

Same data; Different interpretations

Bishal Gyawali, G. & Prasad, V., Nov 1 2016, In : Journal of Clinical Oncology. 34, 31, p. 3729-3732 4 p.

Research output: Contribution to journalComment/debate

3 Scopus citations