Knight Cancer Institute

Research Output 1990 2019

2019
Open Access
Myelodysplastic Syndromes
Homologous Transplantation
Acute Myeloid Leukemia
Hematopoietic Stem Cell Transplantation
Transplantation
Drug Approval
Quality Control
Randomized Controlled Trials
Standard of Care
Antineoplastic Agents
Radiation Oncology
Internship and Residency
Publications
Research
Career Choice

A phase 2 study to assess the pharmacokinetics and pharmacodynamics of CPX-351 and its effects on cardiac repolarization in patients with acute leukemias

Lin, T. L., Newell, L., Stuart, R. K., Michaelis, L. C., Rubenstein, E., Pentikis, H. S., Callahan, T., Alvarez, D., Liboiron, B. D., Mayer, L. D., Wang, Q., Banerjee, K. & Louie, A. C., Jan 1 2019, In : Cancer Chemotherapy and Pharmacology.

Research output: Contribution to journalArticle

Open Access
Pharmacodynamics
Daunorubicin
Pharmacokinetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia

A Phase II Study Alternating Erlotinib With Second-line mFOLFOX6 or FOLFIRI for Metastatic Colorectal Cancer

Kearney, M. R., Chen, E. Y., Vaccaro, G., Strother, J., Burt, A., Todd, K., Donovan, J., Kampa-Schittenhelm, K. M. & Lopez, C., Jan 1 2019, In : Anticancer Research. 39, 1, p. 245-252 8 p.

Research output: Contribution to journalArticle

irinotecan
Colorectal Neoplasms
oxaliplatin
Neutropenia
Combination Drug Therapy

Association of Antiepileptic Medications with Outcomes after Allogeneic Hematopoietic Cell Transplantation with Busulfan/Cyclophosphamide Conditioning

McCune, J. S., Wang, T., Bo-Subait, K., Aljurf, M., Beitinjaneh, A., Bubalo, J., Cahn, J. Y., Cerny, J., Chhabra, S., Cumpston, A., Dupuis, L. L., Lazarus, H. M., Marks, D. I., Maziarz, R., Norkin, M., Prestidge, T., Mineishi, S., Krem, M. M., Pasquini, M. & Martin, P. J., Jan 1 2019, In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Busulfan
Cell Transplantation
Phenytoin
Anticonvulsants
Cyclophosphamide
1 Citation (Scopus)

A systematic review of trial-level meta-analyses measuring the strength of association between surrogate end-points and overall survival in oncology

Haslam, A., Hey, S. P., Gill, J. & Prasad, V., Jan 1 2019, In : European Journal of Cancer. 106, p. 196-211 16 p.

Research output: Contribution to journalReview article

Meta-Analysis
Validation Studies
Biomarkers
Survival
Randomized Controlled Trials

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

Merino, D., Weber, T. S., Serrano, A., Vaillant, F., Liu, K., Pal, B., Di Stefano, L., Schreuder, J., Lin, D., Chen, Y., Labat, M-L., Schumacher, T. N., Cameron, D., Smyth, G. K., Papenfuss, A. T., Lindeman, G. J., Visvader, J. E. & Naik, S. H., Dec 1 2019, In : Nature communications. 10, 1, 766.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Heterografts
breast
Tumors
tumors
1 Citation (Scopus)

Cancer screening: A modest proposal for prevention

Kim, M. S., Nishikawa, G. & Prasad, V., Mar 1 2019, In : Cleveland Clinic journal of medicine. 86, 3, p. 157-160 4 p.

Research output: Contribution to journalComment/debate

Open Access
Early Detection of Cancer

Case Reports in the Age of Twitter

Cifu, A. S., Vandross, A. L. & Prasad, V., Jan 1 2019, In : American Journal of Medicine.

Research output: Contribution to journalEditorial

Open Access

Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer

Butler, T. M., Boniface, C. T., Johnson-Camacho, K., Tabatabaei, S., Melendez, D., Kelley, T., Gray, J., Corless, C. & Spellman, P., Apr 1 2019, In : Cold Spring Harbor molecular case studies. 5, 2

Research output: Contribution to journalArticle

Open Access
Chemotherapy
Tumors
Assays
Breast Neoplasms
Drug Therapy

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 othersBorthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. & Tyner, J., Dec 1 2019, In : Nature Communications. 10, 1, 244.

Research output: Contribution to journalArticle

leukemias
mutations
Acute Myeloid Leukemia
Mutation
inhibitors

Combined iron oxide nanoparticle ferumoxytol and gadolinium contrast enhanced MRI define glioblastoma pseudoprogression

Barajas, R., Hamilton, B., Schwartz, D., Mcconnell, H. L., Pettersson, D., Horvath, A., Szidonya, L., Varallyay, C. G., Firkins, J., Jaboin, J., Kubicky, C. D., Raslan, A., Dogan, A., Cetas, J., Ciporen, J., Han, S. J., Ambady, P., Muldoon, L., Woltjer, R. R., Rooney, W. & 1 othersNeuwelt, E., Mar 18 2019, In : Neuro-Oncology. 21, 4, p. 517-526 10 p.

Research output: Contribution to journalArticle

Open Access
Ferrosoferric Oxide
Gadolinium
Glioblastoma
Nanoparticles
Isocitrate Dehydrogenase
2 Citations (Scopus)

CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

Edwards, D. K., Watanabe-Smith, K., Rofelty, A., Damnernsawad, A., Laderas, T., Lamble, A., Lind, E., Kaempf, A., Mori, M. T., Rosenberg, M., d’Almeida, A., Long, N., Agarwal, A., Sweeney, D. T., Loriaux, M., McWeeney, S. & Tyner, J., Feb 7 2019, In : Blood. 133, 6, p. 588-599 12 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Acute Myeloid Leukemia
Macrophage Colony-Stimulating Factor
Cytokines
Cells

Current Activities of the Coalition of Cancer Cooperative Groups

Coalition of Cancer Cooperative Groups, Jan 1 2019, In : Journal of the National Cancer Institute. 111, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Clinical Trials
Research
National Cancer Institute (U.S.)
Neoplasms
Private Sector
1 Citation (Scopus)

Discovery and characterization of recurrent, targetable ALK fusions in leiomyosarcoma

Davis, L., Nusser, K. D., Przybyl, J., Pittsenbarger, J., Hofmann, N. E., Varma, S., Vennam, S., Debiec-Rychter, M., van de Rijn, M. & Davare, M., Mar 1 2019, In : Molecular Cancer Research. 17, 3, p. 676-685 10 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Phosphotransferases
Sarcoma
Smooth Muscle Myocytes
Neoplasms

Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors

Modestino, A. E., Skowronski, E. A., Pruitt, C., Taub, P. R., Herbst, K., Schmid-Schönbein, G. W., Heller, M. M. & Mills, P. J., Jan 1 2019, In : Journal of the American College of Nutrition.

Research output: Contribution to journalArticle

Open Access
Insulin Receptor
Type 2 Diabetes Mellitus
Meals
Peptide Hydrolases
Matrix Metalloproteinases

Erratum: Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells (eLife (2019) 8 PII: e47174)

Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribeiro, R., Viola, S. K., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Mar 29 2019, In : eLife. 8

Research output: Contribution to journalComment/debate

Open Access
Exosomes
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Medicine
Bone

Essere un medico conservativo

Mandrola, J., Cifu, A., Prasad, V. & Foy, A., Apr 1 2019, In : Recenti Progressi in Medicina. 110, 4, p. 156-158 3 p.

Research output: Contribution to journalReview article

Estimation of Study Time Reduction Using Surrogate End Points Rather Than Overall Survival in Oncology Clinical Trials

Chen, E. Y., Joshi, S. K., Tran, A. & Prasad, V., Jan 1 2019, In : JAMA Internal Medicine.

Research output: Contribution to journalArticle

Biomarkers
Clinical Trials
United States Food and Drug Administration
Drug Approval
Survival

Extreme mechanical diversity of human telomeric DNA revealed by fluorescence-force spectroscopy

Mitra, J., Makurath, M. A., Ngo, T., Troitskaia, A., Chemla, Y. R. & Ha, T., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 17, p. 8350-8359 10 p.

Research output: Contribution to journalArticle

G-Quadruplexes
Fluorescence Spectrometry
DNA
Optical Tweezers
Fluorescence Resonance Energy Transfer

Feasibility and cost analysis of day 4 granulocyte colony-stimulating factor mobilized peripheral blood progenitor cell collection from HLA-matched sibling donors

Newell, L., SHOOP, KELSEA. M., KNIGHT, REBEKAH. J., MURRAY, SARA. N., KWOCK, ROGELYN. P., JACOBY, CAROL. E., Slater, S., ALLEN, BRYON. E., OTTOWA, CASONDRA., COTA, B. R. A. D., APPEL, PEGGY. L., COOK, RACHEL. J., Maziarz, R. & Meyers, G., Jan 1 2019, In : Cytotherapy.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Siblings
Blood Cells
Stem Cells
Tissue Donors

FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells

Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribiero, R., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Feb 5 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Exosomes
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Protein-Tyrosine Kinases
Bone

Genistein treatment duration effects biomarkers of cell motility in human prostate

Zhang, H., Gordon, R., Li, W., Yang, X., Pattanayak, A., Fowler, G., Zhang, L., Catalona, W. J., Ding, Y., Xu, L., Huang, X., Jovanovic, B., Kelly, D. L., Jiang, H. & Bergan, R., Mar 1 2019, In : PloS one. 14, 3, e0214078.

Research output: Contribution to journalArticle

Open Access
Genistein
genistein
Biomarkers
cell movement
Cell Movement

Healthcare expenditures of older patients with AML are similar between HMA and intensive induction chemotherapy

Lachowiez, C., Kearney, M., Meyers, G., Maziarz, R. & Cook, R. J., Jan 1 2019, In : Leukemia and Lymphoma.

Research output: Contribution to journalLetter

Induction Chemotherapy
Health Expenditures
Delivery of Health Care

Involvement of the PI3K/Akt/Nrf2 Signaling Pathway in Resveratrol-Mediated Reversal of Drug Resistance in HL-60/ADR Cells

Li, Y., Guo, Y., Feng, Z., Bergan, R., Li, B., Qin, Y., Zhao, L., Zhang, Z. & Shi, M., Jan 1 2019, In : Nutrition and Cancer.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Drug Resistance
Doxorubicin
Cell Line
HL-60 Cells

Is the side effect profile of protons really safer than photons for intracranial disease?

McClelland, S., Jaboin, J., Watson, G. A. & Zellars, R. C., Jan 1 2019, In : Clinical Neurology and Neurosurgery. 176, p. 8-9 2 p.

Research output: Contribution to journalEditorial

Relative Biological Effectiveness
Proton Therapy
Photons
Protons
Stroke

Long-term stroke risk in meningioma patients treated with conventionally fractionated photon-based radiation therapy

McClelland, S., Mitin, T., Kubicky, C. D. & Jaboin, J., Jan 1 2019, In : Journal of Radiosurgery and SBRT. 6, 1, p. 77-79 3 p.

Research output: Contribution to journalLetter

Meningioma
Photons
Radiotherapy
Stroke

Maintenance avelumab versus continuation of first-line chemotherapy in gastric cancer: JAVELIN Gastric 100 study design

Moehler, M., Ryu, M. H., Dvorkin, M., Lee, K. W., Coşkun, H., Wong, R., Chung, H. C., Poltoratsky, A., Tsuji, A., Yen, C. J., Muntean, A. S., Le Sourd, S., Vaccaro, G., Overton, L., Boku, N., Wainberg, Z. A., Patel, M., Sharma, M., Xiong, H., Conti, I. & 2 othersTaieb, J. & Bang, Y. J., Feb 1 2019, In : Future Oncology. 15, 6, p. 567-577 11 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Esophagogastric Junction
Stomach
oxaliplatin
Maintenance

Making adjuvant therapy decisions with uncertain data

Gyawali, B. & Prasad, V., Mar 1 2019, In : Annals of Oncology. 30, 3, p. 361-364 4 p.

Research output: Contribution to journalReview article

Open Access
Therapeutics
1 Citation (Scopus)

Metastasis-free survival in prostate cancer: Faster drug approvals, better drugs?

Parikh, R. B. & Prasad, V., Feb 1 2019, In : Journal of Clinical Oncology. 37, 4, p. 266-268 3 p.

Research output: Contribution to journalArticle

Drug Approval
Prostatic Neoplasms
Neoplasm Metastasis
Pharmaceutical Preparations
3 Citations (Scopus)

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy

Ghaemi, M. S., DiGiulio, D. B., Contrepois, K., Callahan, B., Ngo, T., Lee-Mcmullen, B., Lehallier, B., Robaczewska, A., McIlwain, D., Rosenberg-Hasson, Y., Wong, R. J., Quaintance, C., Culos, A., Stanley, N., Tanada, A., Tsai, A., Gaudilliere, D., Ganio, E., Han, X., Ando, K. & 23 othersMcNeil, L., Tingle, M., Wise, P., Maric, I., Sirota, M., Wyss-Coray, T., Winn, V. D., Druzin, M. L., Gibbs, R., Darmstadt, G. L., Lewis, D. B., Partovi Nia, V., Agard, B., Tibshirani, R., Nolan, G., Snyder, M. P., Relman, D. A., Quake, S. R., Shaw, G. M., Stevenson, D. K., Angst, M. S., Gaudilliere, B. & Aghaeepour, N., Jan 1 2019, In : Bioinformatics. 35, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

Open Access
Metabolome
Microbiota
Pregnancy
Proteome
Transcriptome

Mutational analysis of patients with colorectal cancer in CALGB/SWOG 80405 identifies new roles of microsatellite instability and tumor mutational burden for patient outcome

Innocenti, F., Ou, F. S., Qu, X., Zemla, T. J., Niedzwiecki, D., Tam, R., Mahajan, S., Goldberg, R. M., Bertagnolli, M. M., Blanke, C., Sanoff, H., Atkins, J., Polite, B., Venook, A. P., Lenz, H. J. & Kabbarah, O., Jan 1 2019, In : Journal of Clinical Oncology. 37, 14, p. 1217-1227 11 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Tumor Burden
Colorectal Neoplasms
Neoplasms
Survival

Novel Approaches for Systemic Mastocytosis

Fletcher, L. & Borate, U., Mar 1 2019, In : Current Opinion in Hematology. 26, 2, p. 112-118 7 p.

Research output: Contribution to journalArticle

Systemic Mastocytosis
4'-N-benzoylstaurosporine
Clinical Trials
Mutation
Proto-Oncogenes
1 Citation (Scopus)

Polatuzumab vedotin or pinatuzumab vedotin plus rituximab in patients with relapsed or refractory non-Hodgkin lymphoma: final results from a phase 2 randomised study (ROMULUS)

Morschhauser, F., Flinn, I. W., Advani, R., Sehn, L. H., Diefenbach, C., Kolibaba, K., Press, O. W., Salles, G., Tilly, H., Chen, A., Assouline, S., Cheson, B. D., Dreyling, M., Hagenbeek, A., Zinzani, P. L., Jones, S., Cheng, J., Lu, D., Penuel, E., Hirata, J. & 3 othersWenger, M., Chu, Y. W. & Sharman, J., May 1 2019, In : The Lancet Haematology. 6, 5, p. e254-e265

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Follicular Lymphoma
Lymphoma, Large B-Cell, Diffuse
Neutropenia
pinatuzumab vedotin

Pracinostat plus azacitidine in older patients with newly diagnosed acute myeloid leukemia: results of a phase 2 study

Garcia-Manero, G., Abaza, Y., Takahashi, K., Medeiros, B. C., Arellano, M., Khaled, S. K., Patnaik, M., Odenike, O., Sayar, H., Tummala, M., Patel, P., Maness-Harris, L., Stuart, R., Traer, E., Karamlou, K., Yacoub, A., Ghalie, R., Giorgino, R. & Atallah, E., Feb 26 2019, In : Blood advances. 3, 4, p. 508-518 11 p.

Research output: Contribution to journalArticle

Azacitidine
Acute Myeloid Leukemia
Disease-Free Survival
Leukemia
Confidence Intervals
1 Citation (Scopus)

Predicting response to BET inhibitors using computational modeling: A BEAT AML project study

Drusbosky, L. M., Vidva, R., Gera, S., Lakshminarayana, A. V., Shyamasundar, V. P., Agrawal, A. K., Talawdekar, A., Abbasi, T., Vali, S., Tognon, C. E., Kurtz, S. E., Tyner, J., McWeeney, S., Druker, B. & Cogle, C. R., Feb 1 2019, In : Leukemia Research. 77, p. 42-50 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Genomics
Computational Biology
MAP Kinase Signaling System
Chromosome Aberrations

Publisher Correction: Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer (Nature Communications, (2019), 10, 1, (766), 10.1038/s41467-019-08595-2)

Merino, D., Weber, T. S., Serrano, A., Vaillant, F., Liu, K., Pal, B., Di Stefano, L., Schreuder, J., Lin, D., Chen, Y., Labat, M-L., Schumacher, T. N., Cameron, D., Smyth, G. K., Papenfuss, A. T., Lindeman, G. J., Visvader, J. E. & Naik, S. H., Dec 1 2019, In : Nature communications. 10, 1, 1945.

Research output: Contribution to journalComment/debate

Open Access
Triple Negative Breast Neoplasms
Heterografts
histograms
breast
cancer

Quantitative atomic force microscopy provides new insight into matrix vesicle mineralization

Plaut, J. S., Strzelecka-Kiliszek, A., Bozycki, L., Pikula, S., Buchet, R., Mebarek, S., Chadli, M., Bolean, M., Simao, A. M. S., Ciancaglini, P., Magrini, A., Rosato, N., Magne, D., Girard-Egrot, A., Farquharson, C., Esener, S., Millan, J. L. & Bottini, M., May 30 2019, In : Archives of Biochemistry and Biophysics. 667, p. 14-21 8 p.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Cartilage
Atomic force microscopy
Nucleation
Elastic Modulus

RADIANS: A Multidisciplinary Central Nervous System Clinic Model for Radiation Oncology and Neurosurgery Practice

McClelland, S., Mitin, T., Jaboin, J. & Ciporen, J., Feb 1 2019, In : World Neurosurgery. 122, p. 8-10 3 p.

Research output: Contribution to journalArticle

Radiation Oncology
Neurosurgery
Central Nervous System
Radiotherapy
Radiosurgery

Real-world Evidence - What Does It Really Mean?

Nabhan, C., Klink, A. & Prasad, V., Jan 1 2019, In : JAMA Oncology.

Research output: Contribution to journalReview article

Registration studies — when should patients be deemed ineligible for aggressive therapy?

Cook, R. J., Gill, J. & Prasad, V., Jan 1 2019, In : Nature Reviews Clinical Oncology.

Research output: Contribution to journalComment/debate

Therapeutics

Relevance of Prognostic Factors in the Era of Targeted Therapies in CLL

Kittai, A. S., Lunning, M. & Danilov, A., Jan 1 2019, In : Current Hematologic Malignancy Reports.

Research output: Contribution to journalReview article

Biomarkers
Therapeutics
Phase III Clinical Trials
Chromosome Aberrations
Research

Revised International Staging System Is Predictive and Prognostic for Early Relapse (<24 months) after Autologous Transplantation for Newly Diagnosed Multiple Myeloma

Gopalakrishnan, S., D'Souza, A., Scott, E., Fraser, R., Davila, O., Shah, N., Gale, R. P., Kamble, R., Diaz, M. A., Lazarus, H. M., Savani, B. N., Hildebrandt, G. C., Solh, M., Freytes, C. O., Lee, C., Kyle, R. A., Usmani, S. Z., Ganguly, S., Assal, A., Berdeja, J. & 14 othersKanate, A. S., Dhakal, B., Meehan, K., Kindwall-Keller, T., Saad, A., Locke, F., Seo, S., Nishihori, T., Gergis, U., Gasparetto, C., Mark, T., Nieto, Y., Kumar, S. & Hari, P., Jan 1 2019, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Autologous Transplantation
Multiple Myeloma
Recurrence
Survival
Cell Transplantation

Should Evidence Come with an Expiration Date?

Greene, P., Prasad, V. & Cifu, A., Jan 1 2019, In : Journal of general internal medicine.

Research output: Contribution to journalArticle

Silica cloaking of adenovirus enhances gene delivery while reducing immunogenicity

Sapre, A. A., Yong, G., Yeh, Y. S., Ruff, L. E., Plaut, J. S., Sayar, Z., Agarwal, A., Martinez, J., Nguyen, T. N., Liu, Y. T., Messmer, B. T., Esener, S. & Fischer, J., Mar 10 2019, In : Journal of Controlled Release. 297, p. 48-59 12 p.

Research output: Contribution to journalArticle

Viral Genes
Adenoviridae
Silicon Dioxide
Heterografts
Glioma

Switching patients in the age of long-acting recombinant products?

Escobar, M., Santagostino, E., Mancuso, M. E., Coppens, M., Balasa, V., Taylor, J., Iorio, A. & Negrier, C., Jan 14 2019, In : Expert Review of Hematology. 12, sup1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Hemorrhage
Safety
Factor IX
Expert Testimony

Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

Deibler, K. K., Schiltz, G. E., Clutter, M. R., Mishra, R. K., Vagadia, P. P., O'Connor, M., George, M. D., Gordon, R., Fowler, G., Bergan, R. & Scheidt, K. A., Jan 1 2019, In : ChemMedChem.

Research output: Contribution to journalArticle

MAP Kinase Kinase 4
Benzoic Acid
Molecular modeling
Oncology
p38 Mitogen-Activated Protein Kinases

Targeting mitochondria in cancer therapy could provide a basis for the selective anticancer activity

Rozanov, D., Cheltsov, A., Nilsen, A., Boniface, C., Forquer, I., Korkola, J., Gray, J., Tyner, J., Tognon, C. E., Mills, G. & Spellman, P., Mar 1 2019, In : PloS one. 14, 3, e0205623.

Research output: Contribution to journalArticle

Open Access
Mitochondria
Assays
mitochondria
therapeutics
neoplasms
1 Citation (Scopus)

Targeting ubiquitin-activating enzyme induces ER stress-mediated apoptosis in B-cell lymphoma cells

Best, S., Hashiguchi, T., Kittai, A., Bruss, N., Paiva, C., Okada, C., Liu, T., Berger, A. & Danilov, A., Jan 8 2019, In : Blood advances. 3, 1, p. 51-62 12 p.

Research output: Contribution to journalArticle

Ubiquitin-Activating Enzymes
Endoplasmic Reticulum Stress
Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Apoptosis