Xiangshu Xiao

Associate Professor

  • 1035 Citations
  • 18 h-Index
20002018
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Cyclic AMP Response Element-Binding Protein Medicine & Life Sciences
Transcription Chemical Compounds
Genes Chemical Compounds
Topoisomerase I Inhibitors Chemical Compounds
Peptoids Chemical Compounds
Type I DNA Topoisomerase Chemical Compounds
Camptothecin Chemical Compounds
DNA Chemical Compounds

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Projects 2010 2016

Targeting EWS-ATF1 in CCSST

Xiao, X.

Project: Research project

Chemical Inhibitors of CREB-mediated Gene Transcription

Xiao, X.

National Institutes of Health

9/1/107/31/16

Project: Research projectResearch Project

Cyclic AMP Response Element-Binding Protein
Genes
Neoplasms
Antineoplastic Agents
Prostatic Neoplasms

Research Output 2000 2018

  • 1035 Citations
  • 18 h-Index
  • 46 Article
  • 2 Review article

A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks

Li, B. X., Chen, J., Chao, B., Zheng, Y. & Xiao, X., Sep 26 2018, In : ACS Central Science. 4, 9, p. 1201-1210 10 p.

Research output: Contribution to journalArticle

Lamins
DNA
Repair
Ligands
Proteins
2 Citations

Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins

Li, B. X., Chen, J., Chao, B., David, L. & Xiao, X., May 18 2018, In : ACS Chemical Biology. 13, 5, p. 1380-1387 8 p.

Research output: Contribution to journalArticle

Lamins
Intermediate Filament Proteins
Lamin Type A
Cytoskeletal Proteins
Actin Cytoskeleton

CBP modulates sensitivity to dasatinib in pre-BCRþ acute lymphoblastic leukemia

Duque-Afonso, J., Lin, C. H., Han, K., Morgens, D. W., Jeng, E. E., Weng, Z., Jeong, J., Wong, S. H. K., Zhu, L., Wei, M. C., Chae, H. D., Schrappe, M., Cario, G., Duyster, J., Xiao, X., Sakamoto, K. M., Bassik, M. C. & Cleary, M. L., Nov 15 2018, In : Cancer Research. 78, 22, p. 6497-6508 12 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Therapeutics
Catenins
Dasatinib
Protein-Tyrosine Kinases
1 Citations

Drugging homologous recombination: Back to the future

Sanford-Crane, H., Pejovic, T. & Xiao, X., Jun 1 2018, In : Future Medicinal Chemistry. 10, 11, p. 1279-1281 3 p.

Research output: Contribution to journalReview article

Homologous Recombination

Small molecule nAS-E targeting cAMP response element binding protein (CREB) and CREB-binding protein interaction inhibits breast cancer bone metastasis

Jiang, M., Yan, Y., Yang, K., Liu, Z., Qi, J., Zhou, H., Qian, N., Zhou, Q., Wang, T., Xu, X., Xiao, X. & Deng, L., Jan 1 2018, (Accepted/In press) In : Journal of cellular and molecular medicine.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Bone Neoplasms
Protein Binding
Carrier Proteins
Breast Neoplasms