Richard Goodman

Professor

  • 20824 Citations
  • 69 h-Index
1971 …2019

Research output per year

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Research Output

  • 20824 Citations
  • 69 h-Index
  • 166 Article
  • 1 Chapter
  • 1 Comment/debate
1990
217 Scopus citations

Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements

Maue, R. A., Kraner, S. D., Goodman, R. & Mandel, G., 1990, In : Neuron. 4, 2, p. 223-231 9 p.

Research output: Contribution to journalArticle

185 Scopus citations

Panel discussion I: Gene regulation, August 7, 1989

Goodman, R., Sep 1990, In : Metabolism. 39, 9 SUPPL. 2, p. 20-21 2 p.

Research output: Contribution to journalArticle

Panel discussion II: Biosynthesis and processing, August 7, 1989

Goodman, R., Sep 1990, In : Metabolism. 39, 9 SUPPL. 2, p. 33-34 2 p.

Research output: Contribution to journalArticle

Regulation of neuropeptide gene expression

Goodman, R., 1990, In : Annual Review of Neuroscience. 13, 1, p. 111-127 17 p.

Research output: Contribution to journalArticle

142 Scopus citations

Somatostatin gene regulation: An overview

Goodman, R., Rehfuss, R. P., Verhave, M., Ventimiglia, R. & Low, M. J., 1990, In : Metabolism. 39, 9 SUPPL. 2, p. 2-5 4 p.

Research output: Contribution to journalArticle

15 Scopus citations
1989

Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity

Sevarino, K. A., Stork, P., Ventimiglia, R., Mandel, G. & Goodman, R., Apr 7 1989, In : Cell. 57, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Characterization and expression of the gene-encoding rat thyrotropin-releasing hormone (TRH)

Lee, S. L., Sevarino, K., Roos, B. A. & Goodman, R., 1989, In : Annals of the New York Academy of Sciences. 553, p. 14-28 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cryptic human growth hormone gene sequences direct gonadotroph-specific expression in transgenic mice

Low, M. J., Goodman, R. & Ebert, K. M., 1989, In : Molecular Endocrinology. 3, 12, p. 2028-2033 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Distinguishable promoter elements are involved in transcriptional activation by E1a and cyclic AMP

Lee, K. A. W., Fink, J. S., Goodman, R. & Green, M. R., 1989, In : Molecular and Cellular Biology. 9, 10, p. 4390-4397 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Expression of diverse Na+ channel messenger RNAs in rat myocardium. Evidence for a cardiac-specific Na+ channel

Sills, M. N., Xu, Y. C., Baracchini, E., Goodman, R., Cooperman, S. S., Mandel, G. & Chien, K. R., 1989, In : Journal of Clinical Investigation. 84, 1, p. 331-336 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Primary structure and functional expression of a mammalian skeletal muscle sodium channel

Trimmer, J. S., Cooperman, S. S., Tomiko, S. A., Zhou, J., Crean, S. M., Boyle, M. B., Kalen, R. G., Sheng, Z., Barchi, R. L., Sigworth, F. J., Goodman, R., Agnew, W. S. & Mandel, G., 1989, In : Neuron. 3, 1, p. 33-49 17 p.

Research output: Contribution to journalArticle

464 Scopus citations

Thyrotropin-releasing hormone (TRH) precursor processing. Characterization of mature TRH and non-TRH peptides synthesized by transfected mammalian cells

Sevarino, K. A., Goodman, R., Spiess, J., Jackson, I. M. D. & Wu, P., 1989, In : Journal of Biological Chemistry. 264, 36, p. 21529-21535 7 p.

Research output: Contribution to journalArticle

33 Scopus citations
1988

A Moloney MLV-rat somatotropin fusion gene produces biologically active somatotropin in a transgenic pig

Ebert, K. M., Low, M. J., Overstrom, E. W., Buonomo, F. C., Baile, C. A., Roberts, T. J., Lee, A., Mandel, G. & Goodman, R., 1988, In : Molecular Endocrinology. 2, 3, p. 277-283 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Biosynthesis of thyrotropin-releasing hormone by a rat medullary thyroid carcinoma cell line

Sevarino, K. A., Wu, P., Jackson, I. M. D., Roos, B. A., Mandel, G. & Goodman, R., 1988, In : Journal of Biological Chemistry. 263, 2, p. 620-623 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Chapter 14 Tissue-Specific Expression of Genes Encoding the Rat Voltage-Gated Sodium Channel

Grubman, S. A., Cooperman, S. S., Begley, M. P., Weintraub, J. L., Goodman, R. & Mandel, G., 1988, In : Current Topics in Membranes and Transport. 33, C, p. 277-288 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Selective induction of brain type II Na+ channels by nerve growth factor

Mandel, G., Cooperman, S. S., Maue, R. A., Goodman, R. & Brehm, P., 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 3, p. 924-928 5 p.

Research output: Contribution to journalArticle

117 Scopus citations

Structure of the gene encoding rat thyrotropin releasing hormone

Lee, S. L., Stewart, K. & Goodman, R., 1988, In : Journal of Biological Chemistry. 263, 32, p. 16604-16609 6 p.

Research output: Contribution to journalArticle

113 Scopus citations

The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements

Riabowol, K. T., Fink, J. S., Gilman, M. Z., Walsh, D. A., Goodman, R. & Feramisco, J. R., 1988, In : Nature. 336, 6194, p. 83-86 4 p.

Research output: Contribution to journalArticle

136 Scopus citations
146 Scopus citations
1987

Biosynthesis of pancreatic islet hormones

Goodman, R., Leiter, A., Low, M. J., Montminy, M. R., Tsukada, T., Fink, J. S. & Mandel, G., 1987, In : Hepatology. 7, 1 SUPPL.

Research output: Contribution to journalArticle

1 Scopus citations

Cell-specific processing of preprosomatostatin in cultured neuroendocrine cells.

Sevarino, K. A., Felix, R., Banks, C. M., Low, M. J., Montminy, M. R., Mandel, G. & Goodman, R., Apr 15 1987, In : Journal of Biological Chemistry. 262, 11, p. 4987-4993 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

Genomic organization and deduced amino acid sequence of a putative sodium channel gene in Drosophila

Salkoff, L., Butler, A., Wei, A., Scavarda, N., Giffen, K., Ifune, C., Goodman, R. & Mandel, G., 1987, In : Science. 237, 4816, p. 744-749 6 p.

Research output: Contribution to journalArticle

188 Scopus citations

Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP

Tsukada, T., Fink, J. S., Mandel, G. & Goodman, R., 1987, In : Journal of Biological Chemistry. 262, 18, p. 8743-8747 5 p.

Research output: Contribution to journalArticle

158 Scopus citations

Localization of somatostatin mRNA in the gut, pancreas and thyroid gland of the rat using antisense RNA probes for in situ hybridization.

Höfler, H., Childers, H., Montminy, M. R., Goodman, R., Lechan, R. M., DeLellis, R. A., Tischler, A. S. & Wolfe, H. J., 1987, In : Acta histochemica. Supplementband. 34, p. 101-105 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Modulation of sodium-channel mRNA levels in rat skeletal muscle.

Cooperman, S. S., Grubman, S. A., Barchi, R. L., Goodman, R. & Mandel, G., Dec 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 23, p. 8721-8725 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Peptide YY. Structure of the precursor and expression in exocrine pancreas.

Leiter, A. B., Toder, A., Wolfe, H. J., Taylor, I. L., Cooperman, S., Mandel, G. & Goodman, R., Sep 25 1987, In : Journal of Biological Chemistry. 262, 27, p. 12984-12988 5 p.

Research output: Contribution to journalArticle

57 Scopus citations

Secretion of apolipoprotein A-I in lipoprotein particles following transfection of the human apolipoprotein A-I gene into 3T3 cells

Lamon-Fava, S., Ordovas, J. M., Mandel, G., Forte, T. M., Goodman, R. & Schaefer, E. J., 1987, In : Journal of Biological Chemistry. 262, 19, p. 8944-8947 4 p.

Research output: Contribution to journalArticle

23 Scopus citations

Using the brain to screen cloned genes

Mandel, G. & Goodman, R., 1987, In : Trends in Neurosciences. 10, 3, p. 101-104 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
1986

Cyclic AMP regulates somatostatin mRNA accumulation in primary diencephalic cultures and in transfected fibroblast cells

Montminy, M. R., Low, M. J., Tapia-Arancibia, L., Reichlin, S., Mandel, G. & Goodman, R., 1986, In : Journal of Neuroscience. 6, 4, p. 1171-1176 6 p.

Research output: Contribution to journalArticle

80 Scopus citations

Die Beurteilung neuroendokriner Genexpression von Tumorzellen mit kombinierter in Situ Hybridisierung und Immunzytochemie.

Translated title of the contribution: Detection of neuroendocrine gene expression of tumor cells by combined in situ hybridization and immunocytochemistryHöfler, H., Childers, H., Dayal, Y., Leiter, A., Goodman, R., DeLellis, R., Tischler, A. & Wolfe, H., 1986, In : Verhandlungen der Deutschen Gesellschaft fur Pathologie. 70, p. 211-216 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice

Low, M. J., Lechan, R. M., Hammer, R. E., Brinster, R. L., Habener, J. F., Mandel, G. & Goodman, R., 1986, In : Science. 231, 4741, p. 1002-1004 3 p.

Research output: Contribution to journalArticle

30 Scopus citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene

Montminy, M. R., Sevarino, K. A., Wagner, J. A., Mandel, G. & Goodman, R., 1986, In : Proceedings of the National Academy of Sciences of the United States of America. 83, 18, p. 6682-6686 5 p.

Research output: Contribution to journalArticle

1018 Scopus citations

In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes

Hoefler, H., Childers, H., Montminy, M. R., Lechan, R. M., Goodman, R. & Wolfe, H. J., Nov 1986, In : The Histochemical Journal. 18, 11-12, p. 597-604 8 p.

Research output: Contribution to journalArticle

152 Scopus citations

Somatostatin-containing D cells exhibit immunoreactivity for rat somatostatin cryptic peptide in six mammalian species - An electron-microscopical study

Varndell, I. M., Sikri, K. L., Hennessy, R. J., Kalina, M., Goodman, R., Benoit, R., Diani, A. R. & Polak, J. M., Oct 1986, In : Cell and Tissue Research. 246, 1, p. 197-204 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Somatostatin is targeted to the regulated secretory pathway of gonadotrophs in transgenic mice expressing a metallothionein-somatostatin gene

Low, M. J., Stork, P., Hammer, R. E., Brinster, R. L., Warhol, M. J., Mandel, G. & Goodman, R., 1986, In : Journal of Biological Chemistry. 261, 34, p. 16260-16263 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Thyrotropin-Releasing Hormone Precursor: Characterization in Rat Brain

Lechan, R. M., Ping, W. U., Jackson, I. M. D., Wolf, H., Cooperman, S., Mandel, G. & Goodman, R., 1986, In : Science. 231, 4734, p. 159-161 3 p.

Research output: Contribution to journalArticle

302 Scopus citations
1985

Biosynthesis of rat preprosomatostatin.

Goodman, R., Montminy, M. R., Low, M. J. & Habener, J. F., 1985, In : Advances in Experimental Medicine and Biology. 188, p. 31-47 17 p.

Research output: Contribution to journalArticle

10 Scopus citations

Exons of the human pancreatic polypeptide gene define functional domains of the precursor

Leiter, A. B., Montminy, M. R., Jamieson, E. & Goodman, R., 1985, In : Journal of Biological Chemistry. 260, 24, p. 13013-13017 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Structure of the human vasoactive intestinal polypeptide gene

Tsukada, T., Horovitch, S. J., Montminy, M. R., Mandel, G. & Goodman, R., 1985, In : DNA. 4, 4, p. 293-300 8 p.

Research output: Contribution to journalArticle

79 Scopus citations

Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice

Low, M. J., Hammer, R. E., Goodman, R., Habener, J. F., Palmiter, R. D. & Brinster, R. L., 1985, In : Cell. 41, 1, p. 211-219 9 p.

Research output: Contribution to journalArticle

67 Scopus citations
1984

Developmental expression of the rat somatostatin gene

Zingg, H. H., Goodman, R. & Habener, J. F., 1984, In : Endocrinology. 115, 1, p. 90-94 5 p.

Research output: Contribution to journalArticle

37 Scopus citations

High plasma levels of immunoreactive somatostatin in transgenic mice expressing a metallothionein-somatostatin fusion gene.

Low, M. J., Goodman, R., Brinster, R. L., Palmiter, R. D., Hammer, R. E. & Habener, J. F., 1984, In : Transactions of the Association of American Physicians. 97, p. 205-209 5 p.

Research output: Contribution to journalArticle

Primary structure of the gene encoding rat preprosomatostatin

Montminy, M. R., Goodman, R., Horovitch, S. J. & Habener, J. F., 1984, In : Proceedings of the National Academy of Sciences of the United States of America. 81, 11 I, p. 3337-3340 4 p.

Research output: Contribution to journalArticle

98 Scopus citations

Structure of a precursor to human pancreatic polypeptide

Leiter, A. B., Keutmann, H. T. & Goodman, R., 1984, In : Journal of Biological Chemistry. 259, 23, p. 14702-14705 4 p.

Research output: Contribution to journalArticle

21 Scopus citations
1983

Anglerfish islet pre-proglucagon II: Nucleotide and corresponding amino acid sequence of the cDNA

Lund, P. K., Goodman, R., Montminy, M. R., Dee, P. C. & Habener, J. F., 1983, In : Journal of Biological Chemistry. 258, 5, p. 3280-3284 5 p.

Research output: Contribution to journalArticle

93 Scopus citations
47 Scopus citations

Rat pre-prosomatostatin. Structure and processing by microsomal membranes

Goodman, R., Aron, D. C. & Roos, B. A., 1983, In : Journal of Biological Chemistry. 258, 9, p. 5570-5573 4 p.

Research output: Contribution to journalArticle

170 Scopus citations
1982

Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem

Lund, P. K., Goodman, R., Dee, P. C. & Habener, J. F., 1982, In : Proceedings of the National Academy of Sciences of the United States of America. 79, 2 I, p. 345-349 5 p.

Research output: Contribution to journalArticle

172 Scopus citations