Richard Goodman

Professor

  • 21035 Citations
  • 69 h-Index
1971 …2019

Research output per year

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Research Output

2001

Consensus and Variant cAMP-regulated Enhancers Have Distinct CREB-binding Properties

Craig, J. C., Schumacher, M. A., Mansoor, S. E., Farrens, D. L., Brennan, R. G. & Goodman, R. H., Apr 13 2001, In : Journal of Biological Chemistry. 276, 15, p. 11719-11728 10 p.

Research output: Contribution to journalArticle

53 Scopus citations
9 Scopus citations

CREB-binding Protein and p300 in Transcriptional Regulation

Vo, N. & Goodman, R. H., Apr 27 2001, In : Journal of Biological Chemistry. 276, 17, p. 13505-13508 4 p.

Research output: Contribution to journalShort survey

Open Access
640 Scopus citations

CREB signaling--timing is everything.

Impey, S. & Goodman, R. H., May 15 2001, In : Science's STKE : signal transduction knowledge environment. 2001, 82, p. PE1

Research output: Contribution to journalReview article

55 Scopus citations

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

Ernst, P., Wang, J., Huang, M., Goodman, R. H. & Korsmeyer, S. J., 2001, In : Molecular and cellular biology. 21, 7, p. 2249-2258 10 p.

Research output: Contribution to journalArticle

172 Scopus citations

The split-hybrid system. Uncoding multiprotein networks and defining mutations that affect protein interactions.

Goldman, P. S., DeMaggio, A. J., Goodman, R. H. & Hoekstra, M. F., 2001, In : Methods in molecular biology (Clifton, N.J.). 177, p. 261-270 10 p.

Research output: Contribution to journalArticle

2000

Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP

Zhang, Q., Yao, H., Vo, N. & Goodman, R. H., Dec 19 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 26, p. 14323-14328 6 p.

Research output: Contribution to journalArticle

103 Scopus citations

Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap-1-extracellular signal-regulated kinase pathway

Grewal, S. S., Fass, D. M., Yao, H., Ellig, C. L., Goodman, R. H. & Stork, P. J. S., Nov 3 2000, In : Journal of Biological Chemistry. 275, 44, p. 34433-34441 9 p.

Research output: Contribution to journalArticle

Open Access
113 Scopus citations

CBP/p300 in cell growth, transformation, and development

Goodman, R. H. & Smolik, S., Jul 1 2000, In : Genes and Development. 14, 13, p. 1553-1577 25 p.

Research output: Contribution to journalReview article

1301 Scopus citations

Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo

Chen, Y., Goodman, R. H. & Smolik, S. M., Mar 1 2000, In : Molecular and cellular biology. 20, 5, p. 1616-1625 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers

Bantignies, F., Goodman, R. H. & Smolik, S. M., Dec 1 2000, In : Molecular and cellular biology. 20, 24, p. 9317-9330 14 p.

Research output: Contribution to journalArticle

64 Scopus citations

Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB

Zhang, Q., Vo, N. & Goodman, R. H., Jul 1 2000, In : Molecular and cellular biology. 20, 14, p. 4970-4978 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation

Cardinaux, J. R., Notis, J. C., Zhang, Q., Vo, N., Craig, J. C., Fass, D. M., Brennan, R. G. & Goodman, R. H., Mar 1 2000, In : Molecular and cellular biology. 20, 5, p. 1546-1552 7 p.

Research output: Contribution to journalArticle

141 Scopus citations

The N-terminal domain of p73 interacts with the CH1 domain of p300/CREB binding protein and mediates transcriptional activation and apoptosis

Zeng, X., Li, X., Miller, A., Yuan, Z., Yuan, W., Kwok, R. P. S., Goodman, R. & Lu, H., Feb 1 2000, In : Molecular and cellular biology. 20, 4, p. 1299-1310 12 p.

Research output: Contribution to journalArticle

75 Scopus citations

The structure of a CREB bZIP·somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding

Schumacher, M. A., Goodman, R. H. & Brennan, R. G., Nov 10 2000, In : Journal of Biological Chemistry. 275, 45, p. 35242-35247 6 p.

Research output: Contribution to journalArticle

121 Scopus citations

The yeast split-hybrid system

DeMaggio, A. J., Goldman, P., Shih, H. M., Goodman, R. H. & Hoekstra, M. F., Jan 1 2000, In : Methods in Enzymology. 328, p. 128-137 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
1999

Dream on without calcium

Mandel, G. & Goodman, R. H., Mar 4 1999, In : Nature. 398, 6722, p. 29-30 2 p.

Research output: Contribution to journalShort survey

14 Scopus citations

Mutants of cubitus interruptus that are independent of PKA regulation are independent of hedgehog signaling

Chen, Y., Cardinaux, J. R., Goodman, R. H. & Smolik, S. M., Aug 1 1999, In : Development. 126, 16, p. 3607-3616 10 p.

Research output: Contribution to journalArticle

77 Scopus citations
1998

Activation and repression in the nervous system

Goodman, R. H. & Mandel, G., Jun 1998, In : Current Opinion in Neurobiology. 8, 3, p. 413-417 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

CBP as a transcriptional organizer

Goodman, R. H. & Smolik, Y. S., Dec 1 1998, In : FASEB Journal. 12, 8, p. A1293

Research output: Contribution to journalArticle

Long-distance transcriptional enhancement by the histone acetyltransferase PCAF

Krumm, A., Madisen, L., Yang, X. J., Goodman, R., Nakatani, Y. & Groudine, M., Nov 10 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 23, p. 13501-13506 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Protein kinase a directly regulates the activity and proteolysis of cubitus interruptus

Chen, Y., Gallaher, N., Goodman, R. H. & Smolik, S. M., Mar 3 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 5, p. 2349-2354 6 p.

Research output: Contribution to journalArticle

149 Scopus citations

The coactivator CBP stimulates human T-cell lymphotrophic virus type I tax transactivation in vitro

Kashanchi, F., Duvall, J. F., Kwok, R. P. S., Lundblad, J. R., Goodman, R. H. & Brady, J. N., Dec 18 1998, In : Journal of Biological Chemistry. 273, 51, p. 34646-34652 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

The human T-cell leukemia virus-1 transcriptional activator tax enhances cAMP-responsive element-binding protein (CREB) binding activity through interactions with the DNA minor groove

Lundblad, J. R., Kwok, R. P. S., Laurance, M. E., Huang, M. S., Richards, J. P., Brennan, R. G. & Goodman, R. H., Jul 24 1998, In : Journal of Biological Chemistry. 273, 30, p. 19251-19259 9 p.

Research output: Contribution to journalArticle

62 Scopus citations
1997

Construction of a 1.2-Mb contig surrounding, and molecular analysis of, the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3

Giles, R. H., Petrij, F., Dauwerse, H. G., Den Hollander, A. I., Lushnikova, T., Van Ommen, G. J. B., Goodman, R. H., Deaven, L. L., Doggett, N. A., Peters, D. J. M. & Breuning, M. H., May 15 1997, In : Genomics. 42, 1, p. 96-114 19 p.

Research output: Contribution to journalArticle

58 Scopus citations

Differential activation of viral and cellular promoters by human T-cell lymphotropic virus-1 tax and cAMP-responsive element modulator isoforms

Laurance, M. E., Kwok, R. P. S., Huang, M. S., Richards, J. P., Lundblad, J. R. & Goodman, R. H., Feb 8 1997, In : Journal of Biological Chemistry. 272, 5, p. 2646-2651 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling

Akimaru, H., Chen, Y., Dai, P., Hou, D. X., Nonaka, M., Smolik, S. M., Armstrong, S., Goodman, R. H. & Ishii, S., Apr 17 1997, In : Nature. 386, 6626, p. 735-738 4 p.

Research output: Contribution to journalArticle

229 Scopus citations

The CRE-binding protein dCREB-A is required for Drosophila embryonic development

Rose, R. E., Gallaher, N. M., Andrew, D. J., Goodman, R. H. & Smolik, S. M., Jun 1 1997, In : Genetics. 146, 2, p. 595-606 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

The Multifunctional Role of the Co-Activator CBP in Transcriptional regulation

Goldman, P. S., Tran, V. K. & Goodman, R. H., Dec 1 1997, In : Recent progress in hormone research. 52, p. 103-119 17 p.

Research output: Contribution to journalArticle

177 Scopus citations

The β-adrenergic receptor kinase interacts with the amino terminus of the G protein β subunit

Goldman, P. S., DeMaggio, A. J., Hoekstra, M. F. & Goodman, R. H., Nov 17 1997, In : Biochemical and Biophysical Research Communications. 240, 2, p. 425-429 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
1996

Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB

Richards, J. P., Bächinger, H. P., Goodman, R. H. & Brennan, R. G., Jun 25 1996, In : Journal of Biological Chemistry. 271, 23, p. 13716-13723 8 p.

Research output: Contribution to journalArticle

111 Scopus citations

A positive genetic selection for disrupting protein-protein interactions: Identification of CREB mutations that prevent association with the coactivator CBP

Shih, H. M., Goldman, P. S., Demaggio, A. J., Hollenberg, S. M., Goodman, R. H. & Hoekstra, M. F., Nov 26 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 24, p. 13896-13901 6 p.

Research output: Contribution to journalArticle

83 Scopus citations

Control of cAMP-regulated enhancers by the viral transactivator tax through CREB and the co-activator CBP

Kwok, R. P. S., Laurance, M. E., Lundblad, J. R., Goldman, P. S., Shih, H. M., Connor, L. M., Marriott, S. J. & Goodman, R. H., May 1 1996, In : Nature. 380, 6575, p. 642-646 5 p.

Research output: Contribution to journalArticle

301 Scopus citations

Fluorescence polarization analysis of protein-DNA and protein-protein interactions

Lundblad, J. R., Laurance, M. & Goodman, R. H., Jun 20 1996, In : Molecular Endocrinology. 10, 6, p. 607-612 6 p.

Research output: Contribution to journalShort survey

201 Scopus citations
1995

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

Lundblad, J. R., Kwok, R. P. S., Laurance, M. E., Harter, M. L. & Goodman, R. H., Jan 1 1995, In : Nature. 374, 6517, p. 85-88 4 p.

Research output: Contribution to journalArticle

513 Scopus citations

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

Petrif, F., Giles, R. H., Dauwerse, H. G., Saris, J. J., Hennekam, R. C. M., Masuno, M., Tommerup, N., van Ommen, G. J. B., Goodman, R. H., Peters, D. J. M. & Breuning, M. H., Jul 27 1995, In : Nature. 376, 6538, p. 348-351 4 p.

Research output: Contribution to journalArticle

940 Scopus citations
1994

Modulatory function of CREB·CREMα heterodimers depends upon CREMα phosphorylation

Loriaux, M. M., Brennan, R. G. & Goodman, R. H., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 28839-28843 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R. & Goodman, R. H., Jan 1 1994, In : Nature. 370, 6486, p. 223-226 4 p.

Research output: Contribution to journalArticle

1235 Scopus citations
1993
Open Access
48 Scopus citations

Isolation of Drosophila CREB-B: A Novel CRE-Binding Protein

Usui, T., Smolik, S. M. & Goodman, R. H., Sep 1993, In : DNA and Cell Biology. 12, 7, p. 589-595 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R. & Goodman, R. H., Jan 1 1993, In : Nature. 365, 6449, p. 855-859 5 p.

Research output: Contribution to journalArticle

1688 Scopus citations
1992

3′, 5′-cyclic adenosine monophosphate-regulated enhancer binding (CREB) activity is required for normal growth and differentiated phenotype in the FRTL5 thyroid follicular cell line

Woloshin, P. I., Walton, K. M., Rehfuss, R. P., Goodman, R. H. & Cone, R. D., Oct 1 1992, In : Molecular Endocrinology. 6, 10, p. 1725-1733 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
Open Access
70 Scopus citations

A dominant repressor of cyclic adenosine 3’,5’-monophosphate (cAMP)-regulated enhancer-binding protein activity inhibits the cAMP-mediated induction of the somatostatin promoter in vivo

Walton, K. M., Rehfuss, R. P., Chrivia, J. C., Lochner, J. E. & Goodman, R. H., Apr 1992, In : Molecular Endocrinology. 6, 4, p. 647-655 9 p.

Research output: Contribution to journalArticle

Open Access
200 Scopus citations

Targeted expression of somatostatin in vasopressinergic magnocellular hypothalamic neurons of transgenic mice

Rubinstein, M., Liu, B., Goodman, R. H. & Low, M. J., Apr 1992, In : Molecular and Cellular Neuroscience. 3, 2, p. 152-161 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Vasoactive intestinal polypeptide gene expression in the developing human gastrointestinal tract

Facer, P., Bishop, A. E., Moscoso, G., Terenghi, G., Liu, Y. F., Goodman, R. H., Legon, S. & Polak, J. M., Jan 1992, In : Gastroenterology. 102, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
1991
61 Scopus citations

Primary structure and tissue distribution of anglerfish carboxypeptidase H

Roth, W. W., Mackin, R. B., Spiess, J., Goodman, R. H. & Noe, B. D., Jul 1991, In : Molecular and Cellular Endocrinology. 78, 3, p. 171-178 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A

Rehfuss, R. P., Walton, K. M., Loriaux, M. M. & Goodman, R. H., Nov 22 1991, In : Journal of Biological Chemistry. 266, 28, p. 18431-18434 4 p.

Research output: Contribution to journalArticle

171 Scopus citations
1990

A direct role for c-fos in AP-1-dependent gene transcription.

Herrera, R., Agarwal, S., Walton, K., Satterberg, B., Distel, R. J., Goodman, R., Spiegelman, B. M. & Roberts, T. M., Oct 1990, In : Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1, 10, p. 483-490 8 p.

Research output: Contribution to journalArticle

11 Scopus citations