Richard Goodman

Professor

  • 20780 Citations
  • 69 h-Index
1971 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1971 2019

  • 20780 Citations
  • 69 h-Index
  • 166 Article
  • 1 Chapter
  • 1 Comment/debate
53 Citations (Scopus)

3′,5′-cyclic adenosine monophosphate-regulated enhancer binding (CREB) activity is required for normal growth and differentiated phenotype in the FRTL5 thyroid follicular cell line

Woloshin, P. I., Walton, K. M., Rehfuss, R. P., Goodman, R. & Cone, R. D., 1992, In : Molecular Endocrinology. 6, 10, p. 1725-1733 9 p.

Research output: Contribution to journalArticle

Cyclic AMP
Phenotype
Cell Line
Growth
Clone Cells
632 Citations (Scopus)

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

Vo, N., Klein, M. E., Varlamova, O., Keller, D. M., Yamamoto, T., Goodman, R. & Impey, S., Nov 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 45, p. 16426-16431 6 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
MicroRNAs
Morphogenesis
GTPase-Activating Proteins
Neurons
102 Citations (Scopus)

Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP

Zhang, Q., Yao, H., Vo, N. & Goodman, R., Dec 19 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 26, p. 14323-14328 6 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Acetylation
Adenoviridae
Carrier Proteins
Protein Binding
126 Citations (Scopus)

Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP

Vo, N., Fjeld, C. & Goodman, R., 2001, In : Molecular and Cellular Biology. 21, 18, p. 6181-6188 8 p.

Research output: Contribution to journalArticle

Receptor-Interacting Protein Serine-Threonine Kinases
Co-Repressor Proteins
Acetylation
Cytoplasmic and Nuclear Receptors
Carrier Proteins
16 Citations (Scopus)

Activation and repression in the nervous system

Goodman, R. & Mandel, G., Jun 1998, In : Current Opinion in Neurobiology. 8, 3, p. 413-417 5 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Co-Repressor Proteins
Nervous System
Transcriptional Activation
Transcription Factors
69 Citations (Scopus)
Leucine Zippers
Salivary Glands
Drosophila melanogaster
Cyclic AMP
Transcription Factors
510 Citations (Scopus)

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

Lundblad, J., Kwok, R. P. S., Laurance, M. E., Harter, M. L. & Goodman, R., 1995, In : Nature. 374, 6517, p. 85-88 4 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Caenorhabditis elegans Proteins
Activator Appliances
CREB-Binding Protein
Gene Expression
11 Citations (Scopus)

A direct role for c-fos in AP-1-dependent gene transcription.

Herrera, R., Agarwal, S., Walton, K., Satterberg, B., Distel, R. J., Goodman, R., Spiegelman, B. M. & Roberts, T. M., Oct 1990, In : Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 1, 10, p. 483-490 8 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-jun
Transcription Factor AP-1
Genes
Proto-Oncogene Proteins c-fos
Proteins
226 Citations (Scopus)

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

Keller, D. M., Zeng, X., Wang, Y., Zhang, Q. H., Kapoor, M., Shu, H., Goodman, R., Lozano, G., Zhao, Y. & Lu, H., 2001, In : Molecular Cell. 7, 2, p. 283-292 10 p.

Research output: Contribution to journalArticle

Casein Kinase II
Protein-Serine-Threonine Kinases
Transcriptional Elongation Factors
DNA Damage
Phosphotransferases
199 Citations (Scopus)

A dominant repressor of cyclic adenosine 3′,5′-monophosphate (cAMP)-regulated enhancer-binding protein activity inhibits the cAMP-mediated induction of the somatostatin promoter in vivo

Walton, K. M., Rehfuss, R. P., Chrivia, J. C., Lochner, J. E. & Goodman, R., Apr 1992, In : Molecular Endocrinology. 6, 4, p. 647-655 9 p.

Research output: Contribution to journalArticle

Somatostatin
Adenosine
Carrier Proteins
Teratocarcinoma
Cyclic AMP-Dependent Protein Kinases
43 Citations (Scopus)

Affinity purification of microRNA-133a with the cardiac transcription factor, Hand2

Vo, N., Dalton, R. P., Liu, N., Olson, E. N. & Goodman, R., Nov 9 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 45, p. 19231-19236 6 p.

Research output: Contribution to journalArticle

MicroRNAs
Transcription Factors
Messenger RNA
3' Untranslated Regions
Computational Biology
86 Citations (Scopus)

A genome-wide screen for β-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression

Yochum, G. S., Cleland, R. & Goodman, R., Dec 2008, In : Molecular and Cellular Biology. 28, 24, p. 7368-7379 12 p.

Research output: Contribution to journalArticle

Catenins
myc Genes
Binding Sites
Genome
Gene Expression
76 Citations (Scopus)

Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity

Sevarino, K. A., Stork, P., Ventimiglia, R., Mandel, G. & Goodman, R., Apr 7 1989, In : Cell. 57, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

Endocrine Cells
Rats
Somatostatin-28
Processing
Cell Line
35 Citations (Scopus)

A Moloney MLV-rat somatotropin fusion gene produces biologically active somatotropin in a transgenic pig

Ebert, K. M., Low, M. J., Overstrom, E. W., Buonomo, F. C., Baile, C. A., Roberts, T. J., Lee, A., Mandel, G. & Goodman, R., 1988, In : Molecular Endocrinology. 2, 3, p. 277-283 7 p.

Research output: Contribution to journalArticle

Moloney murine leukemia virus
Gene Fusion
Growth Hormone
Swine
Murine Leukemia Viruses
206 Citations (Scopus)

An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling

Impey, S., Davare, M., Lasiek, A., Fortin, D., Ando, H., Varlamova, O., Obrietan, K., Soderling, T., Goodman, R. & Wayman, G. A., Jan 2010, In : Molecular and Cellular Neuroscience. 43, 1, p. 146-156 11 p.

Research output: Contribution to journalArticle

Dendritic Spines
MicroRNAs
Spine
Neuronal Plasticity
Gene Regulatory Networks
416 Citations (Scopus)

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

Wayman, G. A., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, H. Y. M., Marks, D., Obrietan, K., Soderling, T., Goodman, R. & Impey, S., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9093-9098 6 p.

Research output: Contribution to journalArticle

MicroRNAs
Dendrites
Cyclic AMP Response Element-Binding Protein
Gene Regulatory Networks
Growth
110 Citations (Scopus)

Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB

Richards, J. P., Bächinger, H. P., Goodman, R. & Brennan, R. G., 1996, In : Journal of Biological Chemistry. 271, 23, p. 13716-13723 8 p.

Research output: Contribution to journalArticle

Structural properties
Carrier Proteins
Phosphorylation
Cyclic AMP-Dependent Protein Kinases
DNA
45 Citations (Scopus)

An antisense transcript induced by Wnt/β-catenin signaling decreases E2F4

Yochum, G. S., Cleland, R., McWeeney, S. & Goodman, R., Jan 12 2007, In : Journal of Biological Chemistry. 282, 2, p. 871-878 8 p.

Research output: Contribution to journalArticle

Catenins
Genes
3' Untranslated Regions
Binding Sites
Cells
166 Citations (Scopus)

A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions

Otto, S. J., McCorkle, S. R., Hover, J., Conaco, C., Han, J. J., Impey, S., Yochum, G. S., Dunn, J. J., Goodman, R. & Mandel, G., Jun 20 2007, In : Journal of Neuroscience. 27, 25, p. 6729-6739 11 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Transcriptional Silencer Elements
Genes
Nerve Tissue
Neuroendocrine Tumors
93 Citations (Scopus)

Anglerfish islet pre-proglucagon II: Nucleotide and corresponding amino acid sequence of the cDNA

Lund, P. K., Goodman, R., Montminy, M. R., Dee, P. C. & Habener, J. F., 1983, In : Journal of Biological Chemistry. 258, 5, p. 3280-3284 5 p.

Research output: Contribution to journalArticle

Proglucagon
Glucagon
Amino Acid Sequence
Nucleotides
Complementary DNA
83 Citations (Scopus)

A positive genetic selection for disrupting protein-protein interactions: Identification of CREB mutations that prevent association with the coactivator CBP

Shih, H. M., Goldman, P. S., Demaggio, A. J., Hollenberg, S. M., Goodman, R. & Hoekstra, M. F., Nov 26 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 24, p. 13896-13901 6 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Genetic Selection
Mutation
Phosphorylation
Proteins
54 Citations (Scopus)

A β-catenin/TCF-coordinated chromatin loop at MYC integrates 5′ and 3′ Wnt responsive enhancers

Yochum, G. S., Sherrick, C. M., MacPartlin, M. & Goodman, R., 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 1, p. 145-150 6 p.

Research output: Contribution to journalArticle

Catenins
Chromatin
Mitogens
Gene Expression
Wnt Signaling Pathway
103 Citations (Scopus)

Biosensor reveals multiple sources for mitochondrial NAD+

Cambronne, X., Stewart, M. L., Kim, D., Jones-Brunette, A. M., Morgan, R. K., Farrens, D., Cohen, M. & Goodman, R., Jun 17 2016, In : Science. 352, 6292, p. 1474-1477 4 p.

Research output: Contribution to journalArticle

Biosensing Techniques
NAD
Sirtuins
Mitochondria
Enzymes
1 Citation (Scopus)

Biosynthesis of pancreatic islet hormones

Goodman, R., Leiter, A., Low, M. J., Montminy, M. R., Tsukada, T., Fink, J. S. & Mandel, G., 1987, In : Hepatology. 7, 1 SUPPL.

Research output: Contribution to journalArticle

Pancreatic Hormones
Pancreatic Polypeptide
Vasoactive Intestinal Peptide
Molecular Cloning
Somatostatin
10 Citations (Scopus)

Biosynthesis of rat preprosomatostatin.

Goodman, R., Montminy, M. R., Low, M. J. & Habener, J. F., 1985, In : Advances in Experimental Medicine and Biology. 188, p. 31-47 17 p.

Research output: Contribution to journalArticle

Biosynthesis
Somatostatin
Rats
Genes
Somatostatin-28
20 Citations (Scopus)

Biosynthesis of thyrotropin-releasing hormone by a rat medullary thyroid carcinoma cell line

Sevarino, K. A., Wu, P., Jackson, I. M. D., Roos, B. A., Mandel, G. & Goodman, R., 1988, In : Journal of Biological Chemistry. 263, 2, p. 620-623 4 p.

Research output: Contribution to journalArticle

Thyrotropin-Releasing Hormone
Biosynthesis
Rats
Cells
Cell Line
99 Citations (Scopus)

Calcitonin messenger RNA encodes multiple polypeptides in a single precursor

Jacobs, J. W., Goodman, R., Chin, W. W., Dee, P. C., Habener, J. F., Bell, N. H. & Potts, J. T., 1981, In : Science. 213, 4506, p. 457-459 3 p.

Research output: Contribution to journalArticle

Calcitonin
Messenger RNA
Peptides
Hormones
Glycine

Calcitonin structural gene: Nucleotide sequence of a cloned cDNA

Jacobs, J. W., Goodman, R. & Chin, W. W., 1981, In : Calcified Tissue International. 33, 3, p. 304 1 p.

Research output: Contribution to journalArticle

Calcitonin
Complementary DNA
Genes
112 Citations (Scopus)

Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap-1-extracellular signal-regulated kinase pathway

Grewal, S. S., Fass, D. M., Yao, H., Ellig, C. L., Goodman, R. & Stork, P., Nov 3 2000, In : Journal of Biological Chemistry. 275, 44, p. 34433-34441 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Carrier Proteins
Calcium
Extracellular Signal-Regulated MAP Kinases
Cyclic AMP-Dependent Protein Kinases
21 Citations (Scopus)

Calmodulin-dependent protein kinase IV mediated antagonism of BMP signaling regulates lineage and survival of hematopoietic progenitors

Walters, M. J., Wayman, G. A., Notis, J. C., Goodman, R., Soderling, T. & Christian, J. L., 2002, In : Development. 129, 6, p. 1455-1466 12 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 4
Bone Morphogenetic Proteins
Cyclic AMP Response Element-Binding Protein
Erythrocytes
Hematopoiesis
35 Citations (Scopus)

Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach

Cambronne, X., Shen, R., Auer, P. L. & Goodman, R., Dec 11 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 50, p. 20473-20478 6 p.

Research output: Contribution to journalArticle

RNA-Induced Silencing Complex
MicroRNAs
Proto-Oncogene Proteins c-crk
Zonula Occludens-1 Protein
Prosencephalon
1285 Citations (Scopus)

CBP/p300 in cell growth, transformation, and development

Goodman, R. & Smolik, S., Jul 1 2000, In : Genes and Development. 14, 13, p. 1553-1577 25 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Embryonic and Fetal Development
Amino Acid Sequence Homology
Oncogenic Viruses
DNA Viruses

CBP as a transcriptional organizer

Goodman, R. & Smolik, Y. S., 1998, In : FASEB Journal. 12, 8

Research output: Contribution to journalArticle

Phosphorylation
Drosophila
Processing
Genes
Hedgehogs
25 Citations (Scopus)

Cell-free translation of messenger RNA coding for a precursor of human calcitonin

Goodman, R., Jacobs, J. W. & Habener, J. F., Dec 14 1979, In : Biochemical and Biophysical Research Communications. 91, 3, p. 932-938 7 p.

Research output: Contribution to journalArticle

Calcitonin
Messenger RNA
Peptides
Immune Sera
Membranes
66 Citations (Scopus)

Cell-specific processing of preprosomatostatin in cultured neuroendocrine cells.

Sevarino, K. A., Felix, R., Banks, C. M., Low, M. J., Montminy, M. R., Mandel, G. & Goodman, R., Apr 15 1987, In : Journal of Biological Chemistry. 262, 11, p. 4987-4993 7 p.

Research output: Contribution to journalArticle

Neuroendocrine Cells
Somatostatin-28
Somatostatin
Cultured Cells
Processing
13 Citations (Scopus)

Cell-specific Profiling of Nascent Proteomes Using Orthogonal Enzyme-mediated Puromycin Incorporation

Barrett, R. M., Liu, H. W., Jin, H., Goodman, R. & Cohen, M., Jun 17 2016, In : ACS Chemical Biology. 11, 6, p. 1532-1536 5 p.

Research output: Contribution to journalArticle

Puromycin
Proteome
Cells
Tissue
Enzymes
108 Citations (Scopus)

Cell-type-specific binding of the transcription factor CREB to the cAMP-response element

Cha-Molstad, H., Keller, D. M., Yochum, G. S., Impey, S. & Goodman, R., Sep 14 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 37, p. 13572-13577 6 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Response Elements
Transcription Factors
Protein Binding
CREB-Binding Protein
7 Citations (Scopus)

Chapter 14 Tissue-Specific Expression of Genes Encoding the Rat Voltage-Gated Sodium Channel

Grubman, S. A., Cooperman, S. S., Begley, M. P., Weintraub, J. L., Goodman, R. & Mandel, G., 1988, In : Current Topics in Membranes and Transport. 33, C, p. 277-288 12 p.

Research output: Contribution to journalArticle

Voltage-Gated Sodium Channels
Sodium Channels
Gene Expression
Conotoxins
Sodium Channel Blockers
12 Citations (Scopus)

Characterization and expression of the gene-encoding rat thyrotropin-releasing hormone (TRH)

Lee, S. L., Sevarino, K., Roos, B. A. & Goodman, R., 1989, In : Annals of the New York Academy of Sciences. 553, p. 14-28 15 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Recombinant Fusion Proteins
Restriction Mapping
Organ Specificity
Gene encoding
76 Citations (Scopus)

Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy

Keller, D. M., McWeeney, S., Arsenlis, A., Drouin, J., Wright, C. V. E., Wang, H., Wollheim, C. B., White, P., Kaestner, K. H. & Goodman, R., Nov 2 2007, In : Journal of Biological Chemistry. 282, 44, p. 32084-32092 9 p.

Research output: Contribution to journalArticle

Microarray Analysis
Microarrays
Chromatin
Transcription Factors
Genes
217 Citations (Scopus)
Bombesin Receptors
Bombesin
Organism Cloning
Complementary DNA
Fibroblasts
52 Citations (Scopus)

Consensus and Variant cAMP-regulated Enhancers Have Distinct CREB-binding Properties

Craig, J. C., Schumacher, M. A., Mansoor, S. E., Farrens, D., Brennan, R. G. & Goodman, R., Apr 13 2001, In : Journal of Biological Chemistry. 276, 15, p. 11719-11728 10 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Protein Binding
Dimerization
DNA
Ions
58 Citations (Scopus)

Construction of a 1.2-Mb contig surrounding, and molecular analysis of, the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3

Giles, R. H., Petrij, F., Dauwerse, H. G., Den Hollander, A. I., Lushnikova, T., Van Ommen, G. J. B., Goodman, R., Deaven, L. L., Doggett, N. A., Peters, D. J. M. & Breuning, M. H., May 15 1997, In : Genomics. 42, 1, p. 96-114 19 p.

Research output: Contribution to journalArticle

Cosmids
Rubinstein-Taybi Syndrome
Chromosomes
Genes
Acute Myeloid Leukemia
301 Citations (Scopus)

Control of cAMP-regulated enhancers by the viral transactivator tax through CREB and the co-activator CBP

Kwok, R. P. S., Laurance, M. E., Lundblad, J., Goldman, P. S., Shih, H. M., Connor, L. M., Marriott, S. J. & Goodman, R., 1996, In : Nature. 380, 6575, p. 642-646 5 p.

Research output: Contribution to journalArticle

Trans-Activators
Cyclic AMP
tax Gene Products
Phosphorylation
Terminal Repeat Sequences
9 Citations (Scopus)
Cyclic AMP Response Element Modulator
Cyclic AMP Response Element-Binding Protein
Phosphoenolpyruvate
CCAAT-Enhancer-Binding Proteins
Protein Binding
2 Citations (Scopus)

Corrigendum to "An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling" [YMCNE (2010) 146-156]

Impey, S., Davare, M., Lesiak, A., Fortin, D., Ando, H., Varlamova, O., Obrietan, K., Soderling, T., Goodman, R. & Wayman, G. A., Feb 2012, In : Molecular and Cellular Neuroscience. 49, 2, p. 250 1 p.

Research output: Contribution to journalArticle

628 Citations (Scopus)

CREB-binding Protein and p300 in Transcriptional Regulation

Vo, N. & Goodman, R., Apr 27 2001, In : Journal of Biological Chemistry. 276, 17, p. 13505-13508 4 p.

Research output: Contribution to journalArticle

Genetic Transcription
CREB-Binding Protein
Biological Models
Trans-Activators
Interferon-beta
55 Citations (Scopus)
Cyclic AMP Response Element-Binding Protein
Calcium-Calmodulin-Dependent Protein Kinases
Neuronal Plasticity
Depolarization
Response Elements
15 Citations (Scopus)

Cryptic human growth hormone gene sequences direct gonadotroph-specific expression in transgenic mice

Low, M. J., Goodman, R. & Ebert, K. M., 1989, In : Molecular Endocrinology. 3, 12, p. 2028-2033 6 p.

Research output: Contribution to journalArticle

Gonadotrophs
Human Growth Hormone
Transgenic Mice
Somatostatin
Metallothionein
140 Citations (Scopus)

C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs

Grooteclaes, M., Deveraux, Q., Hildebrand, J., Zhang, Q., Goodman, R. & Frisch, S. M., Apr 15 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 8, p. 4568-4573 6 p.

Research output: Contribution to journalArticle

Gene Expression
Epithelial-Mesenchymal Transition
Apoptosis
Genes
Co-Repressor Proteins