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  • 12 Similar Profiles
Mutation Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Leukemia, Neutrophilic, Chronic Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Medicine & Life Sciences

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Projects 2010 2019

Leukemia, Neutrophilic, Chronic
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ROR1 as a Therapeutic Target in Acute Lymphoblastic Leukemia

Tyner, J.

National Institutes of Health


Project: Research projectCareer Transition Award, Research Transition Award

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Research Output 2002 2018

A novel AGGF1-PDGFRβ fusion in pediatric T-cell acute lymphoblastic leukemia

Zabriskie, M. S., Antelope, O., Verma, A. R., Draper, L. R., Eide, C. A., Pomicter, A. D., Tran, T. H., Druker, B. J., Tyner, J. W., Miles, R. R., Graham, J. M., Hwang, J. Y., Varley, K. E., Toydemir, R. M., Deininger, M. W., Raetz, E. A. & O’Hare, T. Jan 31 2018 In : Haematologica. 103, 2, p. e87-e91

Research output: Contribution to journalComment/debate

1 Citations

BCL6 promotes glioma and serves as a therapeutic target

Xu, L. , Chen, Y. , Dutra-Clarke, M. , Mayakonda, A. , Hazawa, M. , Savinoff, S. E. , Doan, N. , Said, J. W. , Yong, W. H. , Watkins, A. , Yang, H. , Ding, L. W. , Jiang, Y. Y. , Tyner, J. W. , Ching, J. , Kovalik, J. P. , Madan, V. , Chan, S. L. , Müschen, M. , Breunig, J. J. & 3 others Lin, D. C., Koeffler, H. P. & Cavenee, W. K. 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 15

Research output: Contribution to journalArticle

Ribosomal Protein S6
Ribosomal Protein S6 Kinases
Mitogen-Activated Protein Kinase Kinases
2 Citations

Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations

Zhang, H., Reister Schultz, A., Luty, S., Rofelty, A., Su, Y., Means, S., Bottomly, D., Wilmot, B., McWeeney, S. K. & Tyner, J. W. Dec 1 2017 In : Leukemia. 31, 12, p. 2752-2760 9 p.

Research output: Contribution to journalArticle

Colony-Stimulating Factor Receptors
Neoplastic Cell Transformation
STAT5 Transcription Factor
Myeloproliferative Disorders
Sequence Deletion

Cholesterol esterification inhibition and imatinib treatment synergistically inhibit growth of BCR-ABL mutation-independent resistant chronic myelogenous leukemia

Bandyopadhyay, S., Li, J., Traer, E., Tyner, J. W., Zhou, A., Oh, S. T. & Cheng, J. X. Jul 1 2017 In : PLoS ONE. 12, 7, e0179558

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
3 Citations

CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation

Gordon, M. J., Tardi, P., Loriaux, M. M., Spurgeon, S. E., Traer, E., Kovacsovics, T., Mayer, L. D. & Tyner, J. W. Feb 1 2017 In : Leukemia Research. 53, p. 39-49 11 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Myelodysplastic Syndromes