Jeffrey Tyner

Associate Professor

  • 4574 Citations
  • 30 h-Index
20022019
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Projects 2010 2019

Leukemia, Neutrophilic, Chronic
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Mutation
Neoplasms
Phosphotransferases

ROR1 as a Therapeutic Target in Acute Lymphoblastic Leukemia

Tyner, J.

National Institutes of Health

9/1/108/31/16

Project: Research projectCareer Transition Award, Research Transition Award

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Research
Neoplasms
Genes
Therapeutics

Research Output 2002 2018

A novel AGGF1-PDGFRβ fusion in pediatric T-cell acute lymphoblastic leukemia

Zabriskie, M. S., Antelope, O., Verma, A. R., Draper, L. R., Eide, C. A., Pomicter, A. D., Tran, T. H., Druker, B. J., Tyner, J. W., Miles, R. R., Graham, J. M., Hwang, J. Y., Varley, K. E., Toydemir, R. M., Deininger, M. W., Raetz, E. A. & O’Hare, T., Jan 31 2018, In : Haematologica. 103, 2, p. e87-e91

Research output: Contribution to journalComment/debate

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics

ARID1A and CEBPα cooperatively inhibit UCA1 transcription in breast cancer

Guo, X., Zhang, Y., Mayakonda, A., Madan, V., Ding, L. W., Lin, L. H., Zia, S., Gery, S., Tyner, J. W., Zhou, W., Yin, D., Lin, D. C. & Koeffler, H. P., Jul 6 2018, (Accepted/In press) In : Oncogene. p. 1-13 13 p.

Research output: Contribution to journalArticle

Histone Code
Cell Proliferation
Long Noncoding RNA
Breast Neoplasms
Mutation

Automated decision tree to evaluate genetic abnormalities when determining prognostic risk in acute myeloid leukemia

Watanabe-Smith, K., Druker, B. J., Tyner, J. W. & Edwards, D. K., Jul 31 2018, In : Haematologica. 103, 8, p. e351-e355

Research output: Contribution to journalLetter

Decision Trees
Acute Myeloid Leukemia
3 Citations

Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer

Nair, A. , Chung, H. C. , Sun, T. , Tyagi, S. , Dobrolecki, L. E. , Dominguez-Vidana, R. , Kurley, S. J. , Orellana, M. , Renwick, A. , Henke, D. M. , Katsonis, P. , Schmitt, E. , Chan, D. W. , Li, H. , Mao, S. , Petrovic, I. , Creighton, C. J. , Gutierrez, C. , Dubrulle, J. , Stossi, F. & 17 others Tyner, J. W., Lichtarge, O., Lin, C. Y., Zhang, B., Scott, K. L., Hilsenbeck, S. G., Sun, J., Yu, X., Osborne, C. K., Schiff, R., Christensen, J. G., Shields, D. J., Rimawi, M. F., Ellis, M. J., Shaw, C. A., Lewis, M. T. & Westbrook, T. F., May 1 2018, In : Nature Medicine. 24, 4, p. 505-511 7 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Receptor Protein-Tyrosine Kinases
Therapeutics
Neoplasms
Proto-Oncogene Proteins c-met

Disparate effects of Shb gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia

Jamalpour, M., Li, X., Gustafsson, K., Tyner, J. W. & Welsh, M., Apr 1 2018, In : Tumor Biology. 40, 4

Research output: Contribution to journalArticle

Deficiency Diseases
T-Cell Leukemia
Myeloid Cells
Leukemia
B-Lymphocytes