Projects per year
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- 14 Similar Profiles
Acute Myeloid Leukemia
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Protein-Tyrosine Kinases
Medicine & Life Sciences
Leukemia
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Phosphotransferases
Medicine & Life Sciences
Leukemia, Neutrophilic, Chronic
Medicine & Life Sciences
Therapeutics
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2010 2019
Pathogenetic Mechanism and Clinical Targeting of CSF3R-Driven Cancer
4/1/14 → 2/28/19
Project: Research project
Leukemia, Neutrophilic, Chronic
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Mutation
Neoplasms
Phosphotransferases
ROR1 as a Therapeutic Target in Acute Lymphoblastic Leukemia
9/1/10 → 8/31/16
Project: Research project
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Research
Neoplasms
Genes
Therapeutics
Research Output 2002 2019
9
Citations
(Scopus)
Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms
Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 others, , Dec 1 2019, In : Nature Communications. 10, 1, 244.Research output: Contribution to journal › Article
leukemias
mutations
Acute Myeloid Leukemia
Mutation
inhibitors
1
Citation
(Scopus)
Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants
Eide, C. A., Zabriskie, M. S., Savage Stevens, S. L., Antelope, O., Vellore, N. A., Than, H., Schultz, A. R., Clair, P., Bowler, A. D., Pomicter, A. D., Yan, D., Senina, A. V., Qiang, W., Kelley, T. W., Szankasi, P., Heinrich, M. C., Tyner, J. W., Rea, D., Cayuela, J. M., Kim, D. W. & 4 others, , Oct 14 2019, In : Cancer Cell. 36, 4, p. 431-443.e5Research output: Contribution to journal › Article
Protein-Tyrosine Kinases
Adenosine Triphosphate
ponatinib
5
Citations
(Scopus)
CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells
Edwards, D. K., Watanabe-Smith, K., Rofelty, A., Damnernsawad, A., Laderas, T., Lamble, A., Lind, E., Kaempf, A., Mori, M. T., Rosenberg, M., d’Almeida, A., Long, N., Agarwal, A., Sweeney, D. T., Loriaux, M., McWeeney, S. & Tyner, J., Feb 7 2019, In : Blood. 133, 6, p. 588-599 12 p.Research output: Contribution to journal › Article
Hepatocyte Growth Factor
Acute Myeloid Leukemia
Macrophage Colony-Stimulating Factor
Cytokines
Cells
Erratum: Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells (eLife (2019) 8 PII: e47174)
Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribeiro, R., Viola, S. K., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Mar 29 2019, In : eLife. 8Research output: Contribution to journal › Comment/debate
Open Access
Exosomes
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Medicine
Bone
1
Citation
(Scopus)
FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells
Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribiero, R., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Feb 5 2019, In : eLife. 8Research output: Contribution to journal › Article
Open Access
Exosomes
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Protein-Tyrosine Kinases
Bone