Jeffrey Tyner

Associate Professor

  • 4789 Citations
  • 32 h-Index
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  • 9 Similar Profiles
Mutation Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Leukemia, Neutrophilic, Chronic Medicine & Life Sciences
Therapeutics Medicine & Life Sciences

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Projects 2010 2019

Leukemia, Neutrophilic, Chronic
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ROR1 as a Therapeutic Target in Acute Lymphoblastic Leukemia

Tyner, J.

National Institutes of Health


Project: Research projectCareer Transition Award, Research Transition Award

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Research Output 2002 2018

A novel AGGF1-PDGFRβ fusion in pediatric T-cell acute lymphoblastic leukemia

Zabriskie, M. S., Antelope, O., Verma, A. R., Draper, L. R., Eide, C. A., Pomicter, A. D., Tran, T. H., Druker, B. J., Tyner, J. W., Miles, R. R., Graham, J. M., Hwang, J. Y., Varley, K. E., Toydemir, R. M., Deininger, M. W., Raetz, E. A. & O’Hare, T., Jan 31 2018, In : Haematologica. 103, 2, p. e87-e91

Research output: Contribution to journalComment/debate

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
1 Citations

ARID1A and CEBPα cooperatively inhibit UCA1 transcription in breast cancer

Guo, X., Zhang, Y., Mayakonda, A., Madan, V., Ding, L. W., Lin, L. H., Zia, S., Gery, S., Tyner, J. W., Zhou, W., Yin, D., Lin, D. C. & Koeffler, H. P., Jul 6 2018, (Accepted/In press) In : Oncogene. p. 1-13 13 p.

Research output: Contribution to journalArticle

Histone Code
Cell Proliferation
Long Noncoding RNA
Breast Neoplasms

Automated decision tree to evaluate genetic abnormalities when determining prognostic risk in acute myeloid leukemia

Watanabe-Smith, K., Druker, B. J., Tyner, J. W. & Edwards, D. K., Jul 31 2018, In : Haematologica. 103, 8, p. e351-e355

Research output: Contribution to journalLetter

Decision Trees
Acute Myeloid Leukemia
6 Citations

Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer

Nair, A., Chung, H. C., Sun, T., Tyagi, S., Dobrolecki, L. E., Dominguez-Vidana, R., Kurley, S. J., Orellana, M., Renwick, A., Henke, D. M., Katsonis, P., Schmitt, E., Chan, D. W., Li, H., Mao, S., Petrovic, I., Creighton, C. J., Gutierrez, C., Dubrulle, J., Stossi, F. & 17 othersTyner, J. W., Lichtarge, O., Lin, C. Y., Zhang, B., Scott, K. L., Hilsenbeck, S. G., Sun, J., Yu, X., Osborne, C. K., Schiff, R., Christensen, J. G., Shields, D. J., Rimawi, M. F., Ellis, M. J., Shaw, C. A., Lewis, M. T. & Westbrook, T. F., May 1 2018, In : Nature Medicine. 24, 4, p. 505-511 7 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Receptor Protein-Tyrosine Kinases

Disparate effects of Shb gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia

Jamalpour, M., Li, X., Gustafsson, K., Tyner, J. W. & Welsh, M., Apr 1 2018, In : Tumor Biology. 40, 4

Research output: Contribution to journalArticle

Deficiency Diseases
T-Cell Leukemia
Myeloid Cells