Bill Chang

Associate Professor

  • 1987 Citations
  • 23 h-Index
1993 …2019
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  • 17 Similar Profiles
Precursor Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Calcium-Calmodulin-Dependent Protein Kinase Type 2 Medicine & Life Sciences
Calcium-Calmodulin-Dependent Protein Kinases Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Pre-B Cell Receptors Medicine & Life Sciences
Therapeutics Medicine & Life Sciences

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Projects 2005 2006

Aurora Kinase B
DNA Replication Timing
Chromosomes
Genomic Instability
Phosphorylation

Research Output 1993 2019

  • 1987 Citations
  • 23 h-Index
  • 42 Article
  • 1 Letter

Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche

Abdelhamed, S., Butler, J. T., Doron, B., Halse, A., Nemecek, E., Wilmarth, P., Marks, D., Chang, B., Horton, T. & Kurre, P., Jul 1 2019, In : EMBO Reports. 20, 7, e47546.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Acute Myeloid Leukemia
DNA
DNA Damage

Phenotype switch in acute lymphoblastic leukaemia associated with 3 years of persistent CAR T cell directed-CD19 selective pressure

Lucero, O. M., Parker, K., Funk, T., Dunlap, J., Press, R., Gardner, R. A. & Chang, B., Jan 1 2019, In : British Journal of Haematology.

Research output: Contribution to journalLetter

Open Access
Precursor Cell Lymphoblastic Leukemia-Lymphoma
T-Lymphocytes
Phenotype
3 Citations (Scopus)

The TP53 apoptotic network is a primary mediator of resistance to BCL2 inhibition in AML cells

Nechiporuk, T., Kurtz, S. E., Nikolova, O., Liu, T., Jones, C. L., D’alessandro, A., Culp-Hill, R., D’almeida, A., Joshi, S. K., Rosenberg, M., Tognon, C. E., Danilov, A., Druker, B., Chang, B., McWeeney, S. & Tyner, J., Jul 1 2019, In : Cancer discovery. 9, 7, p. 910-925 16 p.

Research output: Contribution to journalArticle

Myeloid Cells
Acute Myeloid Leukemia
Gene Silencing
Drug Combinations
Drug Resistance
16 Citations (Scopus)

Dasatinib plus intensive chemotherapy in children, adolescents, and young adults with philadelphia chromosome–positive acute lymphoblastic leukemia: Results of children’s oncology group trial AALL0622

Slayton, W. B., Schultz, K. R., Kairalla, J. A., Devidas, M., Mi, X., Pulsipher, M. A., Chang, B., Mullighan, C., Iacobucci, I., Silverman, L. B., Borowitz, M. J., Carroll, A. J., Heerema, N. A., Gastier-Foster, J. M., Wood, B. L., Mizrahy, S. L., Merchant, T., Brown, V. I., Sieger, L., Siegel, M. J. & 5 others, Raetz, E. A., Winick, N. J., Loh, M. L., Carroll, W. L. & Hunger, S. P., Aug 1 2018, In : Journal of Clinical Oncology. 36, 22, p. 2306-2313 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Young Adult
Drug Therapy
Hematopoietic Stem Cell Transplantation
Disease-Free Survival
40 Citations (Scopus)

Functional genomic landscape of acute myeloid leukaemia

Tyner, J., Tognon, C. E., Bottomly, D., Wilmot, B., Kurtz, S. E., Savage, S. L., Long, N., Schultz, A. R., Traer, E., Abel, M., Agarwal, A., Blucher, A., Borate, U., Bryant, J., Burke, R., Carlos, A., Carpenter, R., Carroll, J., Chang, B., Coblentz, C. & 68 others, d’Almeida, A., Cook, R., Danilov, A., Dao, K-H., Degnin, M., Devine, D., Dibb, J., Edwards, D. K., Eide, C. A., English, I., Glover, J., Henson, R., Ho, H., Jemal, A., Johnson, K., Johnson, R., Junio, B., Kaempf, A., Leonard, J., Lin, C., Liu, S. Q., Lo, P., Loriaux, M., Luty, S., Macey, T., MacManiman, J., Martinez, J., Mori, M. T., Nelson, D., Nichols, C., Peters, J., Ramsdill, J., Rofelty, A., Schuff, R., Searles, R., Segerdell, E., Smith, R. L., Spurgeon, S., Sweeney, T., Thapa, A., Visser, C., Wagner, J., Watanabe-Smith, K., Werth, K., Wolf, J., White, L., Yates, A., Zhang, H., Cogle, C. R., Collins, R. H., Connolly, D. C., Deininger, M. W., Drusbosky, L., Hourigan, C. S., Jordan, C. T., Kropf, P., Lin, T. L., Martinez, M. E., Medeiros, B. C., Pallapati, R. R., Pollyea, D. A., Swords, R. T., Watts, J. M., Weir, S. J., Wiest, D. L., Winters, R. M., McWeeney, S. & Druker, B., Oct 25 2018, In : Nature. 562, 7728, p. 526-531 6 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
RNA Sequence Analysis
Pharmaceutical Preparations
Exome
Gene Regulatory Networks