Bill Chang

Associate Professor

  • 1952 Citations
  • 23 h-Index
1993 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1993 2019

  • 1952 Citations
  • 23 h-Index
  • 42 Article
  • 1 Letter
2019

Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche

Abdelhamed, S., Butler, J. T., Doron, B., Halse, A., Nemecek, E., Wilmarth, P., Marks, D., Chang, B., Horton, T. & Kurre, P., Jul 1 2019, In : EMBO Reports. 20, 7, e47546.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Acute Myeloid Leukemia
DNA
DNA Damage

Phenotype switch in acute lymphoblastic leukaemia associated with 3 years of persistent CAR T cell directed-CD19 selective pressure

Lucero, O. M., Parker, K., Funk, T., Dunlap, J., Press, R., Gardner, R. A. & Chang, B., Jan 1 2019, In : British Journal of Haematology.

Research output: Contribution to journalLetter

Open Access
Precursor Cell Lymphoblastic Leukemia-Lymphoma
T-Lymphocytes
Phenotype
1 Citation (Scopus)

The TP53 apoptotic network is a primary mediator of resistance to BCL2 inhibition in AML cells

Nechiporuk, T., Kurtz, S. E., Nikolova, O., Liu, T., Jones, C. L., D’alessandro, A., Culp-Hill, R., D’almeida, A., Joshi, S. K., Rosenberg, M., Tognon, C. E., Danilov, A., Druker, B., Chang, B., McWeeney, S. & Tyner, J., Jul 1 2019, In : Cancer discovery. 9, 7, p. 910-925 16 p.

Research output: Contribution to journalArticle

Myeloid Cells
Acute Myeloid Leukemia
Gene Silencing
Drug Combinations
Drug Resistance
2018
16 Citations (Scopus)

Dasatinib plus intensive chemotherapy in children, adolescents, and young adults with philadelphia chromosome–positive acute lymphoblastic leukemia: Results of children’s oncology group trial AALL0622

Slayton, W. B., Schultz, K. R., Kairalla, J. A., Devidas, M., Mi, X., Pulsipher, M. A., Chang, B., Mullighan, C., Iacobucci, I., Silverman, L. B., Borowitz, M. J., Carroll, A. J., Heerema, N. A., Gastier-Foster, J. M., Wood, B. L., Mizrahy, S. L., Merchant, T., Brown, V. I., Sieger, L., Siegel, M. J. & 5 others, Raetz, E. A., Winick, N. J., Loh, M. L., Carroll, W. L. & Hunger, S. P., Aug 1 2018, In : Journal of Clinical Oncology. 36, 22, p. 2306-2313 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Young Adult
Drug Therapy
Hematopoietic Stem Cell Transplantation
Disease-Free Survival
33 Citations (Scopus)

Functional genomic landscape of acute myeloid leukaemia

Tyner, J., Tognon, C. E., Bottomly, D., Wilmot, B., Kurtz, S. E., Savage, S. L., Long, N., Schultz, A. R., Traer, E., Abel, M., Agarwal, A., Blucher, A., Borate, U., Bryant, J., Burke, R., Carlos, A., Carpenter, R., Carroll, J., Chang, B., Coblentz, C. & 68 others, d’Almeida, A., Cook, R., Danilov, A., Dao, K-H., Degnin, M., Devine, D., Dibb, J., Edwards, D. K., Eide, C. A., English, I., Glover, J., Henson, R., Ho, H., Jemal, A., Johnson, K., Johnson, R., Junio, B., Kaempf, A., Leonard, J., Lin, C., Liu, S. Q., Lo, P., Loriaux, M., Luty, S., Macey, T., MacManiman, J., Martinez, J., Mori, M. T., Nelson, D., Nichols, C., Peters, J., Ramsdill, J., Rofelty, A., Schuff, R., Searles, R., Segerdell, E., Smith, R. L., Spurgeon, S., Sweeney, T., Thapa, A., Visser, C., Wagner, J., Watanabe-Smith, K., Werth, K., Wolf, J., White, L., Yates, A., Zhang, H., Cogle, C. R., Collins, R. H., Connolly, D. C., Deininger, M. W., Drusbosky, L., Hourigan, C. S., Jordan, C. T., Kropf, P., Lin, T. L., Martinez, M. E., Medeiros, B. C., Pallapati, R. R., Pollyea, D. A., Swords, R. T., Watts, J. M., Weir, S. J., Wiest, D. L., Winters, R. M., McWeeney, S. & Druker, B., Oct 25 2018, In : Nature. 562, 7728, p. 526-531 6 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
RNA Sequence Analysis
Pharmaceutical Preparations
Exome
Gene Regulatory Networks

Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL

Chow, M., Gao, L., MacManiman, J. D., Bicocca, V. T., Chang, B., Alumkal, J. & Tyner, J., May 30 2018, (Accepted/In press) In : Oncogene. p. 1-12 12 p.

Research output: Contribution to journalArticle

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Protein Transport
B-Lymphoid Precursor Cells
Maintenance
Proteasome Endopeptidase Complex
6 Citations (Scopus)

Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study

Sun, W., Malvar, J., Sposto, R., Verma, A., Wilkes, J. J., Dennis, R., Heym, K., Laetsch, T. W., Widener, M., Rheingold, S. R., Oesterheld, J., Hijiya, N., Sulis, M. L., Huynh, V., Place, A. E., Bittencourt, H., Hutchinson, R., Messinger, Y., Chang, B., Matloub, Y. & 10 others, Ziegler, D. S., Gardner, R., Cooper, T., Ceppi, F., Hermiston, M., Dalla-Pozza, L., Schultz, K. R., Gaynon, P., Wayne, A. S. & Whitlock, J. A., Nov 1 2018, In : Leukemia. 32, 11, p. 2316-2325 10 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lymphoma
Leukemia
B-Lymphocytes
Disease-Free Survival

Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia

Jenkins, C., Luty, S. B., Maxson, J., Eide, C. A., Abel, M. L., Togiai, C., Nemecek, E., Bottomly, D., McWeeney, S., Wilmot, B., Loriaux, M., Chang, B. & Tyner, J., Jul 17 2018, In : Science Signaling. 11, 539, eaao5617.

Research output: Contribution to journalArticle

Juvenile Myelomonocytic Leukemia
Leukemia
Acute Myeloid Leukemia
Myeloid Cells
Mitogen-Activated Protein Kinases
2017
78 Citations (Scopus)

Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes

Ramos, C. A., Ballard, B., Zhang, H., Dakhova, O., Gee, A. P., Mei, Z., Bilgi, M., Wu, M. F., Liu, H., Grilley, B., Bollard, C. M., Chang, B., Rooney, C. M., Brenner, M. K., Heslop, H. E., Dotti, G. & Savoldo, B., Sep 1 2017, In : Journal of Clinical Investigation. 127, 9, p. 3462-3471 10 p.

Research output: Contribution to journalArticle

Antigen Receptors
Lymphocytes
Anaplastic Large-Cell Lymphoma
Hodgkin Disease
T-Lymphocytes
29 Citations (Scopus)

Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia

Frismantas, V., Dobay, M. P., Rinaldi, A., Tchinda, J., Dunn, S. H., Kunz, J., Richter-Pechanska, P., Marovca, B., Pail, O., Jenni, S., Diaz-Flores, E., Chang, B., Brown, T. J., Collins, R. H., Uhrig, S., Balasubramanian, G. P., Bandapalli, O. R., Higi, S., Eugster, S., Voegeli, P. & 17 others, Delorenzi, M., Cario, G., Loh, M. L., Schrappe, M., Stanulla, M., Kulozik, A. E., Muckenthaler, M. U., Saha, V., Irving, J. A., Meisel, R., Radimerski, T., Von Stackelberg, A., Eckert, C., Tyner, J., Horvath, P., Bornhauser, B. C. & Bourquin, J. P., Mar 16 2017, In : Blood. 129, 11, p. e26-e37

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Pharmaceutical Preparations
T-cells
1 Citation (Scopus)

Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group

Bhojwani, D., Burke, M. J., Horton, T., Ziegler, D. S., Sulis, M. L., Schultz, K. R., Wayne, A., Izraeli, S. & Chang, B., Nov 29 2017, (Accepted/In press) In : Pediatric Hematology and Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Therapeutics
Investigational Therapies
Disease Resistance
14 Citations (Scopus)

Stability of patient-specific features of altered DNA replication timing in xenografts of primary human acute lymphoblastic leukemia

Sasaki, T., Rivera-Mulia, J. C., Vera, D., Zimmerman, J., Das, S., Padget, M., Nakamichi, N., Chang, B., Tyner, J., Druker, B., Weng, A. P., Civin, C. I., Eaves, C. J. & Gilbert, D. M., Jul 1 2017, In : Experimental Hematology. 51, p. 71-82.e3

Research output: Contribution to journalArticle

DNA Replication Timing
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Heterografts
Lymphocytes
Serial Passage
2016
22 Citations (Scopus)

A phase i study of quizartinib combined with chemotherapy in relapsed childhood leukemia: A Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) study

Cooper, T. M., Cassar, J., Eckroth, E., Malvar, J., Sposto, R., Gaynon, P., Chang, B., Gore, L., August, K., Pollard, J. A., DuBois, S. G., Silverman, L. B., Oesterheld, J., Gammon, G., Magoon, D., Annesley, C. & Brown, P. A., Aug 15 2016, In : Clinical Cancer Research. 22, 16, p. 4014-4022 9 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Drug Therapy
Therapeutics
Blood Platelets
8 Citations (Scopus)

Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia

Richard, N. P., Pippa, R., Cleary, M. M., Puri, A., Tibbitts, D., Mahmood, S., Christensen, D. J., Jeng, S., McWeeney, S., Look, A. T., Chang, B., Tyner, J., Vitek, M. P., Odero, M. D., Sears, R. & Agarwal, A., 2016, In : Oncotarget. 7, 51, p. 84214-84227 14 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Protein Phosphatase 2
Cell Line
Phosphotransferases
23 Citations (Scopus)

Targeting BCL-2 and ABL/LYN in Philadelphia chromosome-positive acute lymphoblastic leukemia

Leonard, J. T., Rowley, J. S. J., Eide, C. A., Traer, E., Hayes-Lattin, B., Loriaux, M., Spurgeon, S., Druker, B., Tyner, J. & Chang, B., Aug 31 2016, In : Science Translational Medicine. 8, 354, 354ra114.

Research output: Contribution to journalArticle

Philadelphia Chromosome
B-Cell Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Therapeutics
2015
36 Citations (Scopus)

Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes

Huan, J., Hornick, N. I., Goloviznina, N. A., Kamimae-Lanning, A. N., David, L., Wilmarth, P., Mori, M. T., Chevillet, J. R., Narla, A., Roberts, C., Loriaux, M., Chang, B. & Kurre, P., Jun 25 2015, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Exosomes
Hematopoietic Stem Cells
Acute Myeloid Leukemia
Bone Marrow
Exosome Multienzyme Ribonuclease Complex
10 Citations (Scopus)

Preventive antibiotics in pediatric patients with acute myeloid leukemia (AML)

Nolt, D., Lindemulder, S., Meyrowitz, J., Chang, B., Malempati, S., Thomas, G. & Stork, L., Jul 1 2015, In : Pediatric Blood and Cancer. 62, 7, p. 1149-1154 6 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Pediatrics
Anti-Bacterial Agents
Neutropenia
Infection
51 Citations (Scopus)

Self-Enforcing Feedback Activation between BCL6 and Pre-B Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia

Geng, H., Hurtz, C., Lenz, K. B., Chen, Z., Baumjohann, D., Thompson, S., Goloviznina, N. A., Chen, W. Y., Huan, J., LaTocha, D., Ballabio, E., Xiao, G., Lee, J. W., Deucher, A., Qi, Z., Park, E., Huang, C., Nahar, R., Kweon, S. M., Shojaee, S. & 18 others, Chan, L. N., Yu, J., Kornblau, S. M., Bijl, J. J., Ye, B. H., Mark Ansel, K., Paietta, E., Melnick, A., Hunger, S. P., Kurre, P., Tyner, J., Loh, M. L., Roeder, R. G., Druker, B., Burger, J. A., Milne, T. A., Chang, B. & Müschen, M., Mar 9 2015, In : Cancer Cell. 27, 3, p. 409-425 17 p.

Research output: Contribution to journalArticle

Pre-B Cell Receptors
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Clinical Trials
66 Citations (Scopus)

Serum Exosome MicroRNA as a minimally-invasive early biomarker of AML

Hornick, N. I., Huan, J., Doron, B., Goloviznina, N. A., Lapidus, J., Chang, B. & Kurre, P., Jun 12 2015, In : Scientific Reports. 5, 11295.

Research output: Contribution to journalArticle

Exosomes
MicroRNAs
Acute Myeloid Leukemia
Biomarkers
Serum
31 Citations (Scopus)

Sorafenib treatment following hematopoietic stem cell transplant in pediatric FLT3/ITD acute myeloid leukemia

Tarlock, K., Chang, B., Cooper, T., Gross, T., Gupta, S., Neudorf, S., Adlard, K., Ho, P. A., Mcgoldrick, S., Watt, T., Templeman, T., Sisler, I., Garee, A., Thomson, B., Woolfrey, A., Estey, E., Meshinchi, S. & Pollard, J. A., Jun 1 2015, In : Pediatric Blood and Cancer. 62, 6, p. 1048-1054 7 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Acute Myeloid Leukemia
Hematopoietic Stem Cell Transplantation
Pediatrics
Transplants
8 Citations (Scopus)

Therapeutically targetable ALK mutations in leukemia

Maxson, J., Davare, M., Luty, S. B., Eide, C. A., Chang, B., Loriaux, M., Tognon, C. E., Bottomly, D., Wilmot, B., McWeeney, S., Druker, B. & Tyner, J., Jun 1 2015, In : Cancer Research. 75, 11, p. 2146-2150 5 p.

Research output: Contribution to journalArticle

Leukemia
Mutation
Phosphotransferases
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Point Mutation
11 Citations (Scopus)

YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway

Chang, B., Johnson, K., LaTocha, D., Rowley, J. S. J., Bryant, J., Burke, R., Smith, R. L., Loriaux, M., Müschen, M., Mullighan, C., Druker, B. & Tyner, J., Apr 22 2015, In : Journal of Hematology and Oncology. 8, 1, 39.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA Damage
S Phase
Phosphorylation
Cell Line
2013
4 Citations (Scopus)
Precision Medicine
Genes
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Small Interfering RNA
Genome
86 Citations (Scopus)

Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening

Tyner, J., Yang, W. F., Bankhead, A., Fan, G., Fletcher, L. B., Bryant, J., Glover, J. M., Chang, B., Spurgeon, S., Fleming, W., Kovacsovics, T., Gotlib, J. R., Oh, S. T., Deininger, M. W., Zwaan, C. M., Den Boer, M. L., Van Den Heuvel-Eibrink, M. M., O'Hare, T., Druker, B. & Loriaux, M., Jan 1 2013, In : Cancer Research. 73, 1, p. 285-296 12 p.

Research output: Contribution to journalArticle

Leukemia
Phosphotransferases
Pharmaceutical Preparations
High-Throughput Nucleotide Sequencing
Mutation
259 Citations (Scopus)

Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML

Maxson, J., Gotlib, J., Pollyea, D. A., Fleischman, A. G., Agarwal, A., Eide, C. A., Bottomly, D., Wilmot, B., McWeeney, S., Tognon, C. E., Pond, J. B., Collins, R. H., Goueli, B., Stephen, T. O., Michael, W. D., Chang, B., Loriaux, M., Druker, B. & Tyner, J., 2013, In : New England Journal of Medicine. 368, 19, p. 1781-1790 10 p.

Research output: Contribution to journalArticle

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Leukemia, Neutrophilic, Chronic
Mutation
Phosphotransferases
Neoplasms
68 Citations (Scopus)

TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia

Sanda, T., Tyner, J., Gutierrez, A., Ngo, V. N., Glover, J., Chang, B., Yost, A., Ma, W., Fleischman, A. G., Zhou, W., Yang, Y., Kleppe, M., Ahn, Y., Tatarek, J., Kelliher, M. A., Neuberg, D. S., Levine, R. L., Moriggl, R., Müller, M., Gray, N. S. & 5 others, Jamieson, C. H. M., Weng, A. P., Staudt, L. M., Druker, B. & Thomas Look, A., May 2013, In : Cancer Discovery. 3, 5, p. 564-577 14 p.

Research output: Contribution to journalArticle

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
RNA Interference
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-bcl-2
Cell Survival
2012
59 Citations (Scopus)

Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia

Ryba, T., Battaglia, D., Chang, B., Shirley, J. W., Buckley, Q., Pope, B. D., Devidas, M., Druker, B. & Gilbert, D. M., Oct 2012, In : Genome Research. 22, 10, p. 1833-1844 12 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Pediatrics
Epigenomics
Neoplasms
92 Citations (Scopus)

Crosstalk between ROR1 and the Pre-B Cell Receptor Promotes Survival of t(1;19) Acute Lymphoblastic Leukemia

Bicocca, V. T., Chang, B., Masouleh, B. K., Muschen, M., Loriaux, M., Druker, B. & Tyner, J., Nov 13 2012, In : Cancer Cell. 22, 5, p. 656-667 12 p.

Research output: Contribution to journalArticle

Pre-B Cell Receptors
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Phosphorylation
Cell Surface Receptors
Phosphotransferases
21 Citations (Scopus)

Imatinib resistant BCR-ABL1 mutations at relapse in children with Ph +ALL: A Children's Oncology Group (COG) study

Chang, B., Willis, S. G., Stork, L., Hunger, S. P., Carroll, W. L., Camitta, B. M., Winick, N. J., Druker, B. & Schultz, K. R., May 2012, In : British Journal of Haematology. 157, 4, p. 507-510 4 p.

Research output: Contribution to journalArticle

Neoplasm Drug Resistance
Piperazines
bcr-abl Fusion Proteins
Philadelphia Chromosome
Pyrimidines
14 Citations (Scopus)
Gene Rearrangement
Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-Lymphoid Precursor Cells
Stem Cells
Therapeutics
35 Citations (Scopus)

Targeting survivin and p53 in pediatric acute lymphoblastic leukemia

Tyner, J., Jemal, A. M., Thayer, M. M., Druker, B. & Chang, B., Apr 2012, In : Leukemia. 26, 4, p. 623-632 10 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
Cell Line
Inhibitor of Apoptosis Proteins
Philadelphia Chromosome
2009
76 Citations (Scopus)

RNAi screen for rapid therapeutic target identification in leukemia patients

Tyner, J., Deininger, M. W., Loriaux, M., Chang, B., Gotli, J. R., Willis, S. G., Erickson, H., Kovacsovics, T., O'Hare, T., Heinrich, M. & Druker, B., May 26 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 21, p. 8695-8700 6 p.

Research output: Contribution to journalArticle

RNA Interference
Leukemia
Thrombopoietin Receptors
Genome
Technology
2008
9 Citations (Scopus)
Natural Killer T-Cells
T-Cell Lymphoma
Nose
Anaplastic Large-Cell Lymphoma
Human Herpesvirus 4
3 Citations (Scopus)
Menorrhagia
Menstrual Cycle
Hematopoietic Stem Cells
Hemorrhage
Transplants
2007
24 Citations (Scopus)

Chromosomes with delayed replication timing lead to checkpoint activation, delayed recruitment of Aurora B and chromosome instability

Chang, B., Smith, L., Huang, J. & Thayer, M. M., Mar 22 2007, In : Oncogene. 26, 13, p. 1852-1861 10 p.

Research output: Contribution to journalArticle

Chromosomal Instability
Chromosomes
DNA Replication Timing
M Phase Cell Cycle Checkpoints
Aurora Kinase B
30 Citations (Scopus)

p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint

Stauffer, D., Chang, B., Huang, J., Dunn, A. & Thayer, M. M., Mar 30 2007, In : Journal of Biological Chemistry. 282, 13, p. 9678-9687 10 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
DNA Replication
DNA
Cells
Acetyltransferases
2006
5 Citations (Scopus)

Neuroblastoma Found in a 4-Year-Old After Rituximab Therapy for Opsoclonus-Myoclonus

Chang, B., Koch, T., Hopkins, K. & Malempati, S., Sep 2006, In : Pediatric Neurology. 35, 3, p. 213-215 3 p.

Research output: Contribution to journalArticle

Opsoclonus-Myoclonus Syndrome
Neuroblastoma
Therapeutics
Paraneoplastic Syndromes
Autoantigens
2001
76 Citations (Scopus)

Calcium/calmodulin-dependent protein kinase II inhibitor protein: Localization of isoforms in rat brain

Chang, B., Mukherji, S. & Soderling, T., Feb 14 2001, In : Neuroscience. 102, 4, p. 767-777 11 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Protein Kinase Inhibitors
Protein Isoforms
Brain
212 Citations (Scopus)

Cellular Signaling through Multifunctional Ca 2+/Calmodulin-dependent Protein Kinase II

Soderling, T., Chang, B. & Brickey, D., Feb 9 2001, In : Journal of Biological Chemistry. 276, 6, p. 3719-3722 4 p.

Research output: Contribution to journalArticle

Cell signaling
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Signal transduction
Calcium-Calmodulin-Dependent Protein Kinases
Substrate Specificity
1998
104 Citations (Scopus)

Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmission

Pereda, A. E., Bell, T. D., Chang, B., Czernik, A. J., Nairn, A. C., Soderling, T. & Faber, D. S., Oct 27 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 22, p. 13272-13277 6 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Gap Junctions
Synapses
Injections
167 Citations (Scopus)

Characterization of a calmodulin kinase II inhibitor protein in brain

Chang, B., Mukherji, S. & Soderling, T., Sep 1 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 18, p. 10890-10895 6 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Brain
Proteins
Neuronal Plasticity
1995
46 Citations (Scopus)

Identification in the calcineurin A subunit of the domain that binds the regulatory B subunit

Watanabe, Y., Perrino, B. A., Chang, B. & Soderling, T., 1995, In : Journal of Biological Chemistry. 270, 1, p. 456-460 5 p.

Research output: Contribution to journalArticle

Calcineurin
Phosphoric Monoester Hydrolases
Calmodulin
Fusion reactions
Sf9 Cells
1993
118 Citations (Scopus)

The essential mitotic target of calmodulin is the 110-kilodalton component of the spindle pole body in Saccharomyces cerevisiae

Geiser, J. R., Sundberg, H. A., Chang, B., Muller, E. G. D. & Davis, T. N., Dec 1993, In : Molecular and Cellular Biology. 13, 12, p. 7913-7924 12 p.

Research output: Contribution to journalArticle

Spindle Pole Bodies
Calmodulin
Saccharomyces cerevisiae
Amino Acids
Alleles