Projects per year
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- 11 Similar Profiles
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Medicine & Life Sciences
Leukemia
Medicine & Life Sciences
Protein-Tyrosine Kinases
Medicine & Life Sciences
Acute Myeloid Leukemia
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Phosphotransferases
Medicine & Life Sciences
Myeloid Cells
Medicine & Life Sciences
Cytokines
Medicine & Life Sciences
Network
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Projects 2010 2017
- 1 Finished
Role of p27 in chronic myeloid leukemia and its potential as a therapeutic target
4/1/10 → 6/30/17
Project: Research project › Career Transition Award, Research Transition Award
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia
Neoplasms
Therapeutics
Disease Resistance
Research Output 2008 2018
Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy
Singer, J. W., Fleischman, A., Al-Fayoumi, S., Mascarenhas, J. O., Yu, Q. & Agarwal, A., Sep 1 2018, In : Oncotarget. 9, 70, p. 33416-33439 24 p.Research output: Contribution to journal › Review article
Interleukin-1 Receptor-Associated Kinases
Toll-Like Receptor 1
Protein-Serine-Threonine Kinases
Metabolic Diseases
Therapeutics
Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes
Hosseini, M. M., Kurtz, S. E., Abdelhamed, S., Mahmood, S., Davare, M. A., Kaempf, A., Elferich, J., McDermott, J. E., Liu, T., Payne, S. H., Shinde, U., Rodland, K. D., Mori, M., Druker, B. J., Singer, J. W. & Agarwal, A., Mar 29 2018, (Accepted/In press) In : Leukemia. p. 1-14 14 p.Research output: Contribution to journal › Article
Interleukin-1 Receptor-Associated Kinases
Acute Myeloid Leukemia
Myeloid Cells
Therapeutics
Heterografts
Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples
Edwards V, D. K., Sweeney, D. T., Ho, H., Eide, C. A., Rofelty, A., Agarwal, A., Liu, S. Q., Danilov, A. V., Lee, P., Chantry, D., McWeeney, S. K., Druker, B. J., Tyner, J. W., Spurgeon, S. E. & Loriaux, M. M., May 15 2018, In : Oncotarget. 9, 37, p. 24576-24589 14 p.Research output: Contribution to journal › Article
Colony-Stimulating Factor Receptors
Macrophage Colony-Stimulating Factor
B-Cell Chronic Lymphocytic Leukemia
Antineoplastic Agents
Monocytes
4
Citations
Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: Findings and recommendations
Watanabe-Smith, K., Godil, J., Agarwal, A., Tognon, C. & Druker, B., 2017, In : Oncotarget. 8, 8, p. 12596-12606 11 p.Research output: Contribution to journal › Article
Transgenes
Mutation
Intercellular Signaling Peptides and Proteins
Leukemia
Cytokine Receptors
18
Citations
Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia
Carey, A., Edwards, D. K., Eide, C. A., Newell, L., Traer, E., Medeiros, B. C., Pollyea, D. A., Deininger, M. W., Collins, R. H., Tyner, J. W., Druker, B. J., Bagby, G. C., McWeeney, S. K. & Agarwal, A., Mar 28 2017, In : Cell Reports. 18, 13, p. 3204-3218 15 p.Research output: Contribution to journal › Article
Interleukin-1
Acute Myeloid Leukemia
Disease Progression
Screening
Interleukin-1 Receptors