Organization profile

Organization profile

The Department of Physiology & Pharmacology strategically merges systems physiology with chemical biology, spanning from the molecule to the organism. Laboratories within Phys-Pharm carry out cellular and molecular studies, and translate them into the context of whole animal disease models. The department believes that connecting systems-thinking with cutting edge molecular tools will foster exciting science and will be critical to solving the health problems of the 21st century.

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    Projects

    Research Output

    ACLY is the novel signaling target of PIP2/PIP3 and Lyn in acute myeloid leukemia

    Basappa, J., Citir, M., Zhang, Q., Wang, H. Y., Liu, X., Melnikov, O., Yahya, H., Stein, F., Muller, R., Traynor-Kaplan, A., Schultz, C., Wasik, M. A. & Ptasznik, A., May 2020, In : Heliyon. 6, 5, e03910.

    Research output: Contribution to journalArticle

    Open Access
  • A Genetically Encoded Diazirine Analogue for RNA–Protein Photo-crosslinking

    Dziuba, D., Hoffmann, J. E., Hentze, M. W. & Schultz, C., Jan 15 2020, In : ChemBioChem. 21, 1-2, p. 88-93 6 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    A novel class of cardioprotective small-molecule PTP inhibitors

    Antonucci, S., Di Sante, M., Sileikyte, J., Deveraux, J., Bauer, T., Bround, M. J., Menabò, R., Paillard, M., Alanova, P., Carraro, M., Ovize, M., Molkentin, J. D., Cohen, M., Forte, M. A., Bernardi, P., Di Lisa, F. & Murphy, E., Jan 2020, In : Pharmacological Research. 151, 104548.

    Research output: Contribution to journalArticle

  • 1 Scopus citations