Organization profile

Organization profile

The Department of Physiology & Pharmacology strategically merges systems physiology with chemical biology, spanning from the molecule to the organism. Laboratories within Phys-Pharm carry out cellular and molecular studies, and translate them into the context of whole animal disease models. The department believes that connecting systems-thinking with cutting edge molecular tools will foster exciting science and will be critical to solving the health problems of the 21st century.

Fingerprint Dive into the research topics where Physiology & Pharmacology is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Neurons Medicine & Life Sciences
Aromatase Medicine & Life Sciences
Estrogens Medicine & Life Sciences
Brain Medicine & Life Sciences
Solitary Nucleus Medicine & Life Sciences
Baroreflex Medicine & Life Sciences
Hypothalamus Medicine & Life Sciences
Estradiol Medicine & Life Sciences

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Projects 1976 2020

High Fat Diet
Glutamic Acid
Arcuate Nucleus of Hypothalamus
Angiotensin II

Neuroscience Imaging Center at OHSU

Aicher, S., Cornea, A., Keller, T. & Kayton, R.

National Institutes of Health


Project: Research project


Research Output 1971 2019

A Shared Mechanism for the Folding of Voltage-Gated K + Channels

McDonald, S. K., Levitz, T. S. & Valiyaveetil, F., Mar 26 2019, In : Biochemistry. 58, 12, p. 1660-1671 12 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Lipid Bilayers

Cathepsin G Activity as a New Marker for Detecting Airway Inflammation by Microscopy and Flow Cytometry

Guerra, M., Frey, D., Hagner, M., Dittrich, S., Paulsen, M., Mall, M. A. & Schultz, C., Jan 1 2019, In : ACS Central Science.

Research output: Contribution to journalArticle

Cathepsin G
Flow cytometry
Microscopic examination
Pulmonary diseases
Confocal microscopy

Correction to: Structural basis for potency and promiscuity in poly(ADP-ribose) polymerase (PARP) and tankyrase inhibitors (Journal of Medicinal Chemistry (2017) 60: 4 (1262-1271) DOI: 10.1021/acs.jmedchem.6b00990)

Thorsell, A. G., Ekblad, T., Karlberg, T., Löw, M., Pinto, A. F., Trésaugues, L., Moche, M., Cohen, M. & Schüler, H., Jun 27 2019, In : Journal of Medicinal Chemistry. 62, 12, 1 p.

Research output: Contribution to journalComment/debate

Pharmaceutical Chemistry
Inhibitory Concentration 50
Poly(ADP-ribose) Polymerase Inhibitors