Organization profile

Organization profile

The Department of Physiology & Pharmacology strategically merges systems physiology with chemical biology, spanning from the molecule to the organism. Laboratories within Phys-Pharm carry out cellular and molecular studies, and translate them into the context of whole animal disease models. The department believes that connecting systems-thinking with cutting edge molecular tools will foster exciting science and will be critical to solving the health problems of the 21st century.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neurons Medicine & Life Sciences
Aromatase Medicine & Life Sciences
Brain Medicine & Life Sciences
Estrogens Medicine & Life Sciences
Solitary Nucleus Medicine & Life Sciences
Baroreflex Medicine & Life Sciences
Hypothalamus Medicine & Life Sciences
Estradiol Medicine & Life Sciences

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Projects 1976 2020

Nervous System
Autonomic Nervous System
Sudden Cardiac Death
Therapeutics
Research

Lipid signaling in cardiovascular afferent transmission

Andresen, M.

National Institutes of Health

8/15/166/30/20

Project: Research projectResearch Project

High Fat Diet
Pressoreceptors
Baroreflex
Glutamic Acid
Lipids

Obesity-induced sympathoexcitation: role of brain insulin

Brooks, V.

National Institutes of Health

1/15/1612/31/19

Project: Research projectResearch Project

Arcuate Nucleus of Hypothalamus
Obesity
Insulin
Angiotensin II
Brain

Research Output 1971 2018

Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins

Li, B. X., Chen, J., Chao, B., David, L. L. & Xiao, X. May 18 2018 In : ACS Chemical Biology. 13, 5, p. 1380-1387 8 p.

Research output: Contribution to journalArticle

Lamins
Intermediate Filament Proteins
Lamin Type A
Cytoskeletal Proteins
Actin Cytoskeleton

Diverse actions of estradiol on anorexigenic and orexigenic hypothalamic arcuate neurons

Stincic, T. L., Rønnekleiv, O. K. & Kelly, M. J. Jan 1 2018 (Accepted/In press) In : Hormones and Behavior.

Research output: Contribution to journalArticle

Estradiol
Neurons
Pro-Opiomelanocortin
Neuropeptide Y
Membranes

Early prenatal androgen exposure reduces testes size and sperm concentration in sheep without altering neuroendocrine differentiation and masculine sexual behavior

Scully, C. M., Estill, C. T., Amodei, R., McKune, A., Gribbin, K. P., Meaker, M., Stormshak, F. & Roselli, C. E. Jan 1 2018 In : Domestic Animal Endocrinology. 62, p. 1-9 9 p.

Research output: Contribution to journalArticle

sperm concentration
sexual behavior
Spermatogenesis
First Pregnancy Trimester
androgens