Research Output

2020

A Genetically Encoded Diazirine Analogue for RNA–Protein Photo-crosslinking

Dziuba, D., Hoffmann, J. E., Hentze, M. W. & Schultz, C., Jan 15 2020, In : ChemBioChem. 21, 1-2, p. 88-93 6 p.

Research output: Contribution to journalArticle

Open Access

A novel class of cardioprotective small-molecule PTP inhibitors

Antonucci, S., Di Sante, M., Sileikyte, J., Deveraux, J., Bauer, T., Bround, M. J., Menabò, R., Paillard, M., Alanova, P., Carraro, M., Ovize, M., Molkentin, J. D., Cohen, M., Forte, M. A., Bernardi, P., Di Lisa, F. & Murphy, E., Jan 2020, In : Pharmacological Research. 151, 104548.

Research output: Contribution to journalArticle

Cardiac sympathetic nerve transdifferentiation reduces action potential heterogeneity after myocardial infarction

Wang, L., Olivas, A., Francis Stuart, S. D., Tapa, S., Blake, M. R., Woodward, W. R., Habecker, B. A. & Ripplinger, C. M., Mar 1 2020, In : American journal of physiology. Heart and circulatory physiology. 318, 3, p. H558-H565

Research output: Contribution to journalArticle

Estradiol Protects Neuropeptide Y/Agouti-Related Peptide Neurons against Insulin Resistance in Females

Qiu, J., Bosch, M. A., Zhang, C., Rønnekleiv, O. K. & Kelly, M. J., Jan 1 2020, In : Neuroendocrinology. 110, 1-2, p. 105-118 14 p.

Research output: Contribution to journalArticle

Gastrointestinal Tolerability and Absorption of R- Versus R,S-Lipoic Acid in Progressive Multiple Sclerosis: A Randomized Crossover Trial

Cameron, M., Taylor, C., Lapidus, J., Ramsey, K., Koop, D. & Spain, R., Jan 1 2020, (Accepted/In press) In : Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy

Varin, J., Reynolds, M. M., Bouzidi, N., Tick, S., Wohlschlegel, J., Becquart, O., Michiels, C., Dereure, O., Duvoisin, R. M., Morgans, C. W., Sahe, J. A., Samaran, Q., Guillot, B., Pulido, J. S., Audo, I. & Zeitz, C., Apr 2020, In : PloS one. 15, 4, e0231750.

Research output: Contribution to journalArticle

Open Access

Interplay between compartmentalized NAD+ synthesis and consumption: A focus on the PARP family

Cohen, M. S., Mar 1 2020, In : Genes and Development. 34, 5, p. 254-262 9 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Obesity: sex and sympathetics

Shi, Z., Wong, J. & Brooks, V. L., Mar 11 2020, In : Biology of sex differences. 11, 1, 1 p.

Research output: Contribution to journalReview article

Open Access

Phosphatidylinositol 3,4-bisphosphate synthesis and turnover are spatially segregated in the endocytic pathway

Wang, H., Loerke, D., Bruns, C., Müller, R., Koch, P. A., Puchkov, D., Schultz, C. & Haucke, V., Jan 1 2020, In : Journal of Biological Chemistry. 295, 4, p. 1091-1104 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Programmed for Preference: The Biology of Same-Sex Attraction in Rams

Roselli, C. E., Jul 2020, In : Neuroscience and Biobehavioral Reviews. 114, p. 12-15 4 p.

Research output: Contribution to journalReview article

Role for Kisspeptin and Neurokinin B in Regulation of Luteinizing Hormone and Testosterone Secretion in the Fetal Sheep

Amodei, R., Gribbin, K., He, W., Lindgren, I., Corder, K. R., Jonker, S. S., Estill, C. T., Coolen, L. M., Lehman, M. N., Whitler, W., Stormshak, F. & Roselli, C. E., Apr 1 2020, In : Endocrinology. 161, 4

Research output: Contribution to journalArticle

Sites and sources of sympathoexcitation in obese male rats: role of brain insulin

Shi, Z., Zhao, D., Cassaglia, P. A. & Brooks, V. L., Mar 1 2020, In : American journal of physiology. Regulatory, integrative and comparative physiology. 318, 3, p. R634-R648

Research output: Contribution to journalArticle

Synthesis and Cellular Labeling of Caged Phosphatidylinositol Derivatives

Müller, R., Citir, M., Hauke, S. & Schultz, C., Jan 7 2020, In : Chemistry - A European Journal. 26, 2, p. 384-389 6 p.

Research output: Contribution to journalArticle

Open Access
2019

5-HT3R–sourced calcium enhances glutamate release from a distinct vesicle pool

Fawley, J. A., Doyle, M. W. & Andresen, M., Oct 15 2019, In : Brain research. 1721, 146346.

Research output: Contribution to journalArticle

1 Scopus citations

Arcuate Kisspeptin Neurons Coordinate Reproductive Activities with Metabolism

Ronnekleiv, O. K., Qiu, J. & Kelly, M. J., May 23 2019, In : Seminars in Reproductive Medicine. 37, 3, p. 131-140 10 p.

Research output: Contribution to journalReview article

A Shared Mechanism for the Folding of Voltage-Gated K + Channels

McDonald, S. K., Levitz, T. S. & Valiyaveetil, F. I., Mar 26 2019, In : Biochemistry. 58, 12, p. 1660-1671 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

A suite of bioassays to evaluate CREB inhibitors

Li, B. X. & Xiao, X., Jan 1 2019, (Accepted/In press) Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cathepsin G Activity as a New Marker for Detecting Airway Inflammation by Microscopy and Flow Cytometry

Guerra, M., Frey, D., Hagner, M., Dittrich, S., Paulsen, M., Mall, M. A. & Schultz, C., Jan 1 2019, In : ACS Central Science.

Research output: Contribution to journalArticle

3 Scopus citations

Correction to: Structural basis for potency and promiscuity in poly(ADP-ribose) polymerase (PARP) and tankyrase inhibitors (Journal of Medicinal Chemistry (2017) 60: 4 (1262-1271) DOI: 10.1021/acs.jmedchem.6b00990)

Thorsell, A. G., Ekblad, T., Karlberg, T., Löw, M., Pinto, A. F., Trésaugues, L., Moche, M., Cohen, M. & Schüler, H., Jun 27 2019, In : Journal of Medicinal Chemistry. 62, 12, 1 p.

Research output: Contribution to journalComment/debate

Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-Mediated Gene Transcription with 666 - 15

Xie, F., Fan, Q., Li, B. X. & Xiao, X., Jan 1 2019, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Distinct Calcium Sources Define Compartmentalized Synaptic Signaling Domains

Fawley, J. A. & Andresen, M., Jan 1 2019, (Accepted/In press) In : Neuroscientist.

Research output: Contribution to journalReview article

1 Scopus citations

Elastase exocytosis by airway neutrophils is associated with early lung damage in children with cystic fibrosis

AREST-CF and IMPEDE-CF, Apr 1 2019, In : American journal of respiratory and critical care medicine. 199, 7, p. 873-881 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

Smilkstein, M. J., Pou, S., Krollenbrock, A., Bleyle, L. A., Dodean, R. A., Frueh, L., Hinrichs, D. J., Li, Y., Martinson, T., Munar, M. Y., Winter, R. W., Bruzual, I., Whiteside, S., Nilsen, A., Koop, D. R., Kelly, J. X., Kappe, S. H. I., Wilder, B. K. & Riscoe, M. K., Aug 27 2019, In : Malaria Journal. 18, 1, 291.

Research output: Contribution to journalArticle

Open Access

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition

Hirose, K., Payumo, A. Y., Cutie, S., Hoang, A., Zhang, H., Guyot, R., Lunn, D., Bigley, R. B., Yu, H., Wang, J., Smith, M., Gillett, E., Muroy, S. E., Schmid, T., Wilson, E., Field, K. A., Reeder, D. A. M., Maden, M., Yartsev, M. M., Wolfgang, M. J. & 8 others, Grützner, F., Scanlan, T. S., Szweda, L. I., Buffenstein, R., Hu, G., Flamant, F., Olgin, J. E. & Huang, G. N., Jan 1 2019, In : Science. 364, 6436, p. 184-188 5 p.

Research output: Contribution to journalArticle

42 Scopus citations

Flow Cytometry Analysis of Free Intracellular NAD+ Using a Targeted Biosensor

Eller, J. M., Stewart, M. L., Slepian, A. J., Markwardt, S., Wiedrick, J., Cohen, M. S., Goodman, R. H. & Cambronne, X. A., Apr 2019, In : Current Protocols in Cytometry. 88, 1, e54.

Research output: Contribution to journalArticle

1 Scopus citations

Fondation Leducq Transatlantic Network of Excellence Targeting Mitochondria to Treat Heart Disease

Murphy, E., Bernardi, P., Cohen, M., Di Lisa, F., Forte, M., Molkentin, J. D. & Ovize, M., Apr 26 2019, In : Circulation research. 124, 9, p. 1294-1296 3 p.

Research output: Contribution to journalArticle

Open Access

Identification of lamins as the molecular targets of LBL1 using a clickable photoaffinity probe

Xiao, X. & Li, B. X., Jan 1 2019, Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access

Membrane and nuclear initiated estrogenic regulation of homeostasis

Stincic, T. L., Ronnekleiv, O. & Kelly, M., Jan 1 2019, In : Steroids. 108428.

Research output: Contribution to journalArticle

N- And O-Acetylated 3-Iodothyronamines Have No Metabolic or Thermogenic Effects in Male Mice

Gachkar, S., Oelkrug, R., Herrmann, B., Scanlan, T. S., Sun, Q., Biebermann, H., Hoefig, C. S., Schomburg, L. & Mittag, J., Jan 1 2019, (Accepted/In press) In : European Thyroid Journal.

Research output: Contribution to journalArticle

Onset of differentiation is post-transcriptionally controlled in adult neural stem cells

Baser, A., Skabkin, M., Kleber, S., Dang, Y., Gülcüler Balta, G. S., Kalamakis, G., Göpferich, M., Ibañez, D. C., Schefzik, R., Lopez, A. S., Bobadilla, E. L., Schultz, C., Fischer, B. & Martin-Villalba, A., Feb 7 2019, In : Nature. 566, 7742, p. 100-104 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Photolysis of cell-permeant caged inositol pyrophosphates controls oscillations of cytosolic calcium in a β-cell line

Hauke, S., Dutta, A. K., Eisenbeis, V. B., Bezold, D., Bittner, T., Wittwer, C., Thakor, D., Pavlovic, I., Schultz, C. & Jessen, H. J., Jan 1 2019, In : Chemical Science. 10, 9, p. 2687-2692 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Photorelease of 2-Arachidonoylglycerol in Live Cells

Laguerre, A., Hauke, S., Qiu, J., Kelly, M. J. & Schultz, C., Oct 23 2019, In : Journal of the American Chemical Society. 141, 42, p. 16544-16547 4 p.

Research output: Contribution to journalArticle

Prevalence of Cerebrotendinous Xanthomatosis among Patients Diagnosed with Acquired Juvenile-Onset Idiopathic Bilateral Cataracts

Freedman, S. F., Brennand, C., Chiang, J., Debarber, A., Del Monte, M. A., Duell, P. B., Fiorito, J. & Marshall, R., Jan 1 2019, (Accepted/In press) In : JAMA ophthalmology.

Research output: Contribution to journalArticle

Open Access
Open Access

Quantification of phosphoinositides reveals strong enrichment of PIP2 in HIV-1 compared to producer cell membranes

Mücksch, F., Citir, M., Lüchtenborg, C., Glass, B., Traynor-Kaplan, A., Schultz, C., Brügger, B. & Kräusslich, H. G., Dec 1 2019, In : Scientific Reports. 9, 1, 17661.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Radiation-primed hepatocyte transplantation in murine monogeneic dyslipidemia normalizes cholesterol and prevents atherosclerosis

Barahman, M., Zhang, W., Harris, H. Y., Aiyer, A., Kabarriti, R., Kinkhabwala, M., Roy-Chowdhury, N., Beck, A. P., Scanlan, T. T., Roy-Chowdhury, J., Asp, P. & Guha, C., Jan 1 2019, In : Journal of Hepatology.

Research output: Contribution to journalArticle

2 Scopus citations

Resistance to the sympathoexcitatory effects of insulin and leptin in late pregnant rats

Shi, Z., Hansen, K. M., Bullock, K. M., Morofuji, Y., Banks, W. A. & Brooks, V. L., Aug 1 2019, In : Journal of Physiology. 597, 15, p. 4087-4100 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Reversible ADP-ribosylation of RNA

Munnur, D., Bartlett, E., Mikolčević, P., Kirby, I. T., Matthias Rack, J. G., Mikoč, A., Cohen, M. & Ahel, I., Jun 20 2019, In : Nucleic acids research. 47, 11, p. 5658-5669 12 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Second-Generation Inhibitors of the Mitochondrial Permeability Transition Pore with Improved Plasma Stability

Šileikytė, J., Devereaux, J., de Jong, J., Schiavone, M., Jones, K., Nilsen, A., Bernardi, P., Forte, M. & Cohen, M. S., Oct 17 2019, In : ChemMedChem. 14, 20, p. 1771-1782 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sex differences in sympathetic gene expression and cardiac neurochemistry in Wistar Kyoto rats

Bayles, R. G., Tran, J., Olivas, A., Woodward, W., Fei, S. S., Gao, L. & Habecker, B., Jun 1 2019, In : PloS one. 14, 6, e0218133.

Research output: Contribution to journalArticle

Open Access

Sex differences in the sympathoexcitatory response to insulin in obese rats: role of neuropeptide Y

Shi, Z., Cassaglia, P. A., Pelletier, N. E. & Brooks, V., Jan 1 2019, In : Journal of Physiology.

Research output: Contribution to journalArticle

4 Scopus citations

Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics

Kirby, I. T. & Cohen, M., Jan 1 2019, In : Current Topics in Microbiology and Immunology. 420, p. 211-231 21 p.

Research output: Contribution to journalArticle

5 Scopus citations
1 Scopus citations

The Life Science Toolbox Provided by Chemical Biology

Schultz, C., Jan 1 2019, In : Israel Journal of Chemistry.

Research output: Contribution to journalReview article

Thyroid hormone receptor function in maturing ovine cardiomyocytes

Chattergoon, N. N., Louey, S., Scanlan, T., Lindgren, I., Giraud, G. D. & Thornburg, K. L., Apr 15 2019, In : Journal of Physiology. 597, 8, p. 2163-2176 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

TRPM1 Autoantibodies in Melanoma Patients Without Self-Reported Visual Symptoms

Duvoisin, R., Ren, G., Haley, T. L., Taylor, M. H. & Morgans, C., May 1 2019, In : Investigative ophthalmology & visual science. 60, 6, p. 2330-2335 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Understanding diverse TRPV1 signaling – an update [version 1; peer review: 4 approved]

Andresen, M., Jan 1 2019, In : F1000Research. 8, 1978.

Research output: Contribution to journalReview article

Open Access

Visualization of intracellular hydrogen peroxide with the genetically encoded fluorescent probe HyPer in NIH-3T3 cells

Ermakova, Y. G., Mishina, N. M., Schultz, C. & Belousov, V. V., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 259-274 16 p. (Methods in Molecular Biology; vol. 1982).

Research output: Chapter in Book/Report/Conference proceedingChapter