Organization profile

Organization profile

Dedicated to elucidating the structural and mechanical properties of cells and tissues, understanding how these structures are encoded and regulated by genomic features and how genomic aberrations corrupt aspects of structure that lead to disease formation.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Breast Neoplasms Medicine & Life Sciences
Fluorophores Chemical Compounds
Microscopy Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Microscopic examination Chemical Compounds
Cell Line Medicine & Life Sciences
Fluorescence Medicine & Life Sciences
Castration Medicine & Life Sciences

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Profiles

No photo of Summer Gibbs
20042020
No photo of Laura Heiser
20052019
No photo of Xiaolin Nan
20012019

Projects 2010 2020

Oxazines
Robotics
Prostatectomy
Rodentia
Swine
Computer-Assisted Surgery
Fluorescent Dyes
Contrast Media
Mentors
Blood-Nerve Barrier

Research Output 2012 2019

BET bromodomain inhibition blocks the function of a critical AR-independent master regulator network in lethal prostate cancer

Coleman, D. J., Gao, L., King, C. J., Schwartzman, J., Urrutia, J., Sehrawat, A., Tayou, J., Balter, A., Burchard, J., Chiotti, K. E., Derrick, D. S., Sun, D., Xia, Z., Heiser, L. & Alumkal, J., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

Androgen Receptors
Castration
Prostatic Neoplasms
RNA Sequence Analysis
Neoplasms

Diagnostic performance of receptor-specific surgical specimen staining correlates with receptor expression level

Schaefer, J. M., Barth, C. W., Davis, S. C. & Gibbs, S., Feb 1 2019, In : Journal of biomedical optics. 24, 2, p. 1-9 9 p.

Research output: Contribution to journalArticle

staining
margins
Imaging techniques
Coloring Agents
Contrast Media
1 Citation (Scopus)

Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer

Coleman, D. J., Gao, L., Schwartzman, J., Korkola, J., Sampson, D., Derrick, D. S., Urrutia, J., Balter, A., Burchard, J., King, C. J., Chiotti, K. E., Heiser, L. & Alumkal, J., Dec 1 2019, In : Scientific Reports. 9, 1, 3823.

Research output: Contribution to journalArticle

Open Access
Castration
Prostatic Neoplasms
Maintenance
Androgen Receptors
Cell Line