Center for Spatial Systems Biomedicine

Organization profile

Organization profile

Dedicated to elucidating the structural and mechanical properties of cells and tissues, understanding how these structures are encoded and regulated by genomic features and how genomic aberrations corrupt aspects of structure that lead to disease formation.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Breast Neoplasms Medicine & Life Sciences
Fluorophores Chemical Compounds
Microscopy Medicine & Life Sciences
Microscopic examination Chemical Compounds
Neoplasms Medicine & Life Sciences
Fluorescence Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Profiles

No photo of Summer Gibbs

Summer Gibbs

Person: Academic

20042020
No photo of Laura Heiser

Laura Heiser

Person: Academic

20052018
No photo of Xiaolin Nan

Xiaolin Nan

Person: Academic

20012018

Projects 2010 2020

NIR Nerve-specific Fluorescent Imaging for Robotic-assisted Radical Prostatectomy

Gibbs, S.

National Institutes of Health

9/7/16 → 5/31/20

Project: Research project › Research Project

Oxazines
Robotics
Prostatectomy
Rodentia
Swine

Nerve-Specific Near-Infrared Fluorescent Contrast Agents for Image-Guided Surgery

Gibbs, S. & Gibbs-Strauss, S. L.

National Institutes of Health

8/1/10 → 7/31/16

Project: Research project › Research Scientist Development Award - Research & Training

Computer-Assisted Surgery
Fluorescent Dyes
Contrast Media
Mentors
Blood-Nerve Barrier

Research Output 2012 2018

  • 59 Article
  • 4 Conference contribution
  • 3 Comment/debate
  • 1 Chapter

Erratum: Publisher Correction: Combating subclonal evolution of resistant cancer phenotypes (Nature communications (2017) 8 1 (1231))

Brady, S. W., McQuerry, J. A., Qiao, Y., Piccolo, S. R., Shrestha, G., Jenkins, D. F., Layer, R. M., Pedersen, B. S., Miller, R. H., Esch, A., Selitsky, S. R., Parker, J. S., Anderson, L. A., Dalley, B. K., Factor, R. E., Reddy, C. B., Boltax, J. P., Li, D. Y., Moos, P. J., Gray, J. & 8 othersHeiser, L., Buys, S. S., Cohen, A. L., Johnson, W. E., Quinlan, A. R., Marth, G., Werner, T. L. & Bild, A. H., Feb 5 2018, In : Nature communications. 9, 1, 1 p.

Research output: Contribution to journal › Comment/debate

phenotype
cancer
communication
Communication
document markup languages
6 Citations

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function

Sehrawat, A., Gao, L., Wang, Y., Bankhead, A., McWeeney, S., King, C. J., Schwartzman, J., Urrutia, J., Bisson, W. H., Coleman, D. J., Joshi, S. K., Kim, D. H., Sampson, D. A., Weinmann, S., Kallakury, B. V. S., Berry, D. L., Haque, R., Van Den Eeden, S. K., Sharma, S., Bearss, J. & 4 othersBeer, T. T., Thomas, G., Heiser, L. & Alumkal, J., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. E4179-E4188

Research output: Contribution to journal › Article

Gene Regulatory Networks
Neoplasm Genes
Lysine
Prostatic Neoplasms
Castration
3 Citations

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

Watson, S. S., Dane, M., Chin, K-Y., Tatarova, Z., Liu, M., Liby, T., Thompson, W., Smith, R., Nederlof, M., Bucher, E., Kilburn, D., Whitman, M., Sudar, D., Mills, G., Heiser, L., Jonas, O., Gray, J. & Korkola, J., Jan 1 2018, (Accepted/In press) In : Cell Systems.

Research output: Contribution to journal › Article

Protein-Tyrosine Kinases
Breast Neoplasms
Ligands
Cell Line
Hepatocyte Growth Factor