Research Output 1978 2019

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2013
117 Citations (Scopus)

Mobile health: Revolutionizing healthcare through transdisciplinary research

Kumar, S., Nilsen, W., Pavel, M. & Srivastava, M., 2013, In : Computer. 46, 1, p. 28-35 8 p., 6357165.

Research output: Contribution to journalArticle

Health
Monitoring
mHealth
122 Citations (Scopus)

Modeling precision treatment of breast cancer.

Daemen, A., Griffith, O. L., Heiser, L., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. & Gray, J., 2013, In : Genome Biology. 14, 10

Research output: Contribution to journalArticle

breast neoplasms
cancer
Breast Neoplasms
therapeutics
modeling
55 Citations (Scopus)

Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis: Effects of antioxidant therapy with NADPH oxidase inhibition

Liu, Y., Davidson, B. P., Yue, Q., Belcik, T., Xie, A., Inaba, Y., McCarty, O., Tormoen, G. W., Zhao, Y., Ruggeri, Z. M., Kaufmann, B. A. & Lindner, J., Jan 2013, In : Circulation: Cardiovascular Imaging. 6, 1, p. 74-82 9 p.

Research output: Contribution to journalArticle

Molecular Imaging
NADPH Oxidase
Atherosclerosis
Blood Platelets
Antioxidants
8 Citations (Scopus)

Moving the science of behavior change into the 21st century: novel solutions to prevent disease and promote health.

Saranummi, N., Spruijt-Metz, D., Intille, S. S., Korhone, I., Nilsen, W. J. & Pavel, M., Sep 2013, In : IEEE Pulse. 4, 5, p. 22-24 3 p.

Research output: Contribution to journalArticle

Biomedical Engineering
Behavioral Sciences
Preventive Medicine
Biomedical engineering
Health Promotion
1244 Citations (Scopus)

Optical properties of biological tissues: A review

Jacques, S., Jun 7 2013, In : Physics in Medicine and Biology. 58, 11

Research output: Contribution to journalArticle

Melanins
Fats
Water
6 Citations (Scopus)

OtoID: New extended frequency, portable audiometer for ototoxicity monitoring

Dille, M. F., Jacobs, P., Gordon, S. Y., Helt, W. J. & McMillan, G. P., 2013, In : Journal of Rehabilitation Research and Development. 50, 7, p. 997-1006 10 p.

Research output: Contribution to journalArticle

Hospital Units
Hearing Tests
Hearing
American Speech-Language-Hearing Association
Audiology
24 Citations (Scopus)

p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils

Itakura, A., Aslan, J., Kusanto, B. T., Phillips, K. G., Porter, J. E., Newton, P. K., Nan, X., Insall, R. H., Chernoff, J. & McCarty, O., Sep 3 2013, In : PLoS One. 8, 9, e73063.

Research output: Contribution to journalArticle

p21-Activated Kinases
neutrophils
phosphotransferases (kinases)
Neutrophils
guanosinetriphosphatase
23 Citations (Scopus)

P21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear

Aslan, J., Itakura, A., Haley, K., Tormoen, G. W., Loren, C. P., Baker, S. M., Pang, J., Chernoff, J. & McCarty, O., Jul 2013, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 7, p. 1544-1551 8 p.

Research output: Contribution to journalArticle

p21-Activated Kinases
Pseudopodia
Platelet Aggregation
Glycoproteins
Platelet Activation
5 Citations (Scopus)

Phosphatidylserine index as a marker of the procoagulant phenotype of acute myelogenous leukemia cells

Tormoen, G. W., Recht, O., Gruber, A., Levine, R. L. & McCarty, O., Oct 2013, In : Physical Biology. 10, 5, 056010.

Research output: Contribution to journalArticle

Phosphatidylserines
Thromboplastin
Acute Myeloid Leukemia
cancer procoagulant
Phenotype
4 Citations (Scopus)
Factor X
Factor IX
Thromboplastin
Thrombosis
Factor VII
76 Citations (Scopus)
Autophagy
Sirolimus
Neutrophils
methionyl-leucyl-phenylalanine
Neutrophil Activation
247 Citations (Scopus)

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

Verhaak, R. G. W., Tamayo, P., Yang, J. Y., Hubbard, D., Zhang, H., Creighton, C. J., Fereday, S., Lawrence, M., Carter, S. L., Mermel, C. H., Kostic, A. D., Etemadmoghadam, D., Saksena, G., Cibulskis, K., Duraisamy, S., Levanon, K., Sougnez, C., Tsherniak, A., Gomez, S., Onofrio, R. & 21 others, Gabriel, S., Chin, L., Zhang, N., Spellman, P., Zhang, Y., Akbani, R., Hoadley, K. A., Kahn, A., Köbel, M., Huntsman, D., Soslow, R. A., Defazio, A., Birrer, M. J., Gray, J., Weinstein, J. N., Bowtell, D. D., Drapkin, R., Mesirov, J. P., Getz, G., Levine, D. A. & Meyerson, M., Jan 2 2013, In : Journal of Clinical Investigation. 123, 1, p. 517-525 9 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Carcinoma
Genes
Platinum
Survival
11 Citations (Scopus)

Quantification of volume, mass, and density of thrombus formation using brightfield and differential interference contrast microscopy

Baker-Groberg, S. M., Phillips, K. G. & McCarty, O., 2013, In : Journal of Biomedical Optics. 18, 1, 016014.

Research output: Contribution to journalArticle

Microscopic examination
Fibrillar Collagens
Platelets
microscopy
platelets
3 Citations (Scopus)

Rac and Cdc42 team up for platelets

Aslan, J. & McCarty, O., Oct 31 2013, In : Blood. 122, 18, p. 3096-3097 2 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Megakaryocytes
Platelets
Blood
Blood Platelets
114 Citations (Scopus)

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Lovci, M. T., Ghanem, D., Marr, H., Arnold, J., Gee, S., Parra, M., Liang, T. Y., Stark, T. J., Gehman, L. T., Hoon, S., Massirer, K. B., Pratt, G. A., Black, D. L., Gray, J., Conboy, J. G. & Yeo, G. W., Dec 2013, In : Nature Structural and Molecular Biology. 20, 12, p. 1434-1442 9 p.

Research output: Contribution to journalArticle

Alternative Splicing
RNA
Exons
Messenger RNA
Proteins
105 Citations (Scopus)

Reversal of rivaroxaban anticoagulation by haemostatic agents in rats and primates

Perzborn, E., Gruber, A., Tinel, H., Marzec, U. M., Buetehorn, U., Buchmuelle, A., Heitmeier, S. & Laux, V., 2013, In : Thrombosis and Haemostasis. 110, 1, p. 162-172 11 p.

Research output: Contribution to journalArticle

Hemostatics
Anticoagulants
Primates
Bleeding Time
Papio
75 Citations (Scopus)

Rho GTPases in platelet function

Aslan, J. & McCarty, O., Jan 2013, In : Journal of Thrombosis and Haemostasis. 11, 1, p. 35-46 12 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Blood Platelets
Monomeric GTP-Binding Proteins
Platelet Activation
Cell Surface Receptors
5 Citations (Scopus)

Role of coagulation in the recruitment of colon adenocarcinoma cells to thrombus under shear

Baker-Groberg, S. M., Itakura, A., Gruber, A. & McCarty, O., Nov 1 2013, In : American Journal of Physiology - Cell Physiology. 305, 9

Research output: Contribution to journalArticle

Colon
Adenocarcinoma
Thrombosis
Fibrillar Collagens
Fibrinogen
7 Citations (Scopus)

Second site reversion of a mutation near the amino terminus of the HIV-1 capsid protein

Lopez, C., Tsagli, S. M., Sloan, R., Eccles, J. & Barklis, E., Dec 2013, In : Virology. 447, 1-2, p. 95-103 9 p.

Research output: Contribution to journalArticle

Isoleucine
Capsid Proteins
Morphogenesis
Tyrosine
HIV-1
81 Citations (Scopus)

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

Nan, X., Collisson, E. A., Lewis, S., Huang, J., Tamgüney, T. M., Liphardt, J. T., McCormick, F., Gray, J. & Chu, S., Nov 12 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 46, p. 18519-18524 6 p.

Research output: Contribution to journalArticle

Microscopy
Spatial Analysis
Membrane Fusion
Protein-Serine-Threonine Kinases
Neoplasms
1 Citation (Scopus)

Special issue on high-resolution optical imaging

Smith, P. J. S., Davies, I., Galbraith, C. & Stemmer, A., Sep 2013, In : Journal of Optics (United Kingdom). 15, 9, 090201.

Research output: Contribution to journalArticle

Imaging techniques
high resolution
15 Citations (Scopus)

Structure-Activity Relationship of Nerve-Highlighting Fluorophores

Gibbs, S., Xie, Y., Goodwill, H. L., Nasr, K. A., Ashitate, Y., Madigan, V. J., Siclovan, T. M., Zavodszky, M., Tan Hehir, C. A. & Frangioni, J. V., Sep 9 2013, In : PLoS One. 8, 9, e73493.

Research output: Contribution to journalArticle

Fluorophores
fluorescent dyes
structure-activity relationships
Structure-Activity Relationship
nerve tissue

SU‐E‐T‐292: In‐Vivo Blood Oxygen Measurements Via Interstitial Fiber Optic Probe and Photoacoustic Imaging

Campos, D., Torres, A., Lakshman, M., Kissick, M., Kimple, R., Jacques, S. & Yue, Y., 2013, In : Medical Physics. 40, 6, p. 271 1 p.

Research output: Contribution to journalArticle

Radiotherapy
Radiation
Oxygen
Blood Volume
Hemodynamics
22 Citations (Scopus)

Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains

Beatty, K., Williams, M., Carlson, B. L., Swarts, B. M., Warren, R. M., Van Helden, P. D. & Bertozzi, C. R., Aug 6 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 32, p. 12911-12916 6 p.

Research output: Contribution to journalArticle

Sulfatases
Dermatoglyphics
Enzymes
Routine Diagnostic Tests
Communicable Diseases
24 Citations (Scopus)

The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation

Aslan, J., Baker, S. M., Loren, C. P., Haley, K., Itakura, A., Pang, J., Greenberg, D. L., David, L., Manser, E., Chernoff, J. & McCarty, O., Sep 1 2013, In : American Journal of Physiology - Cell Physiology. 305, 5

Research output: Contribution to journalArticle

p21-Activated Kinases
rho GTP-Binding Proteins
Platelet Activation
Thrombin
Blood Platelets
27 Citations (Scopus)

The role of technology and engineering models in transforming healthcare

Pavel, M., Jimison, H. B., Wactlar, H. D., Hayes, T. L., Barkis, W., Skapik, J. & Kaye, J., 2013, In : IEEE Reviews in Biomedical Engineering. 6, p. 156-177 22 p., 6490450.

Research output: Contribution to journalArticle

Health
Information technology
Biomedical engineering
Mobile computing
Learning systems
19 Citations (Scopus)

Topical dual-stain difference imaging for rapid intra-operative tumor identification in fresh specimens

Davis, S. C., Gibbs, S., Gunn, J. R. & Pogue, B. W., Dec 1 2013, In : Optics Letters. 38, 23, p. 5184-5187 4 p.

Research output: Contribution to journalArticle

tumors
surgery
margins
biomarkers
breast
16 Citations (Scopus)

Treatment of severe hand impairment following stroke by combining assisted movement, muscle vibration, and biofeedback

Cordo, P., Wolf, S., Lou, J. S., Bogey, R., Stevenson, M., Hayes, J. & Roth, E., Dec 2013, In : Journal of Neurologic Physical Therapy. 37, 4, p. 194-203 10 p.

Research output: Contribution to journalArticle

Vibration
Hand
Stroke
Muscles
Upper Extremity
2012
130 Citations (Scopus)

A Central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Collisson, E. A., Trejo, C. L., Silva, J. M., Gu, S., Korkola, J., Heiser, L., Charles, R. P., Rabinovich, B. A., Hann, B., Dankort, D., Spellman, P., Phillips, W. A., Gray, J. & McMahon, M., Aug 2012, In : Cancer Discovery. 2, 8, p. 685-693 9 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Maintenance
Cell Line
Mutation
1-Phosphatidylinositol 4-Kinase
10 Citations (Scopus)

A low-dimensional deformation model for cancer cells in flow

Lee, A. M., Berny-Lang, M. A., Liao, S., Kanso, E., Kuhn, P., McCarty, O. & Newton, P. K., Aug 16 2012, In : Physics of Fluids. 24, 8, 081903.

Research output: Contribution to journalArticle

cancer
cells
multiple docking adapters
shear
fluids
6 Citations (Scopus)

Antithrombotic activity of protein S infused without activated protein C in a baboon thrombosis model

Heeb, M. J., Marzec, U., Gruber, A. & Hanson, S. R., Apr 2012, In : Thrombosis and Haemostasis. 107, 4, p. 690-698 9 p.

Research output: Contribution to journalArticle

Papio
Protein S
Protein C
Thrombosis
Blood Platelets
1 Citation (Scopus)

Approximating distributions in stochastic learning

Leen, T. K., Friel, R. & Nielsen, D., Aug 2012, In : Neural Networks. 32, p. 219-228 10 p.

Research output: Contribution to journalArticle

Fokker Planck equation
Learning
Markov Chains
Plasticity
Learning systems
16 Citations (Scopus)

ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

Ordinario, E., Han, H. J., Furuta, S., Heiser, L., Jakkula, L. R., Rodier, F., Spellman, P., Campisi, J., Gray, J., Bissell, M. J., Kohwi, Y. & Kohwi-Shigematsu, T., Dec 10 2012, In : PLoS One. 7, 12, e51786.

Research output: Contribution to journalArticle

Automatic teller machines
breasts
Breast
epithelial cells
Epithelial Cells
59 Citations (Scopus)

Bayesian Inference of Signaling Network Topology in a Cancer Cell Line

Hill, S. M., Lu, Y., Molina, J., Heiser, L., Spellman, P., Speed, T. P., Gray, J., Mills, G. & Mukherjee, S., Nov 2012, In : Bioinformatics. 28, 21, p. 2804-2810 7 p.

Research output: Contribution to journalArticle

Bayesian inference
Network Topology
Cancer
Cells
Topology
12 Citations (Scopus)

Beyond novelty detection: Incongruent events, when general and specific classifiers disagree

Weinshall, D., Zweig, A., Hermansky, H., Kombrink, S., Ohl, F. W., Anemüller, J., Bach, J. H., Van Gool, L., Nater, F., Pajdla, T., Havlena, M. & Pavel, M., 2012, In : IEEE Transactions on Pattern Analysis and Machine Intelligence. 34, 10, p. 1886-1901 16 p., 6122029.

Research output: Contribution to journalArticle

Novelty Detection
Labels
Classifiers
Classifier
Speech recognition
31 Citations (Scopus)

Biomechanics of early cardiac development

Goenezen, S., Rennie, M. Y. & Rugonyi, S., Nov 2012, In : Biomechanics and Modeling in Mechanobiology. 11, 8, p. 1187-1204 18 p.

Research output: Contribution to journalArticle

Biomechanics
Hemodynamics
Biomechanical Phenomena
Cardiac
Imaging techniques
41 Citations (Scopus)

Biomechanics of the chick embryonic heart outflow tract at HH18 using 4D optical coherence tomography imaging and computational modeling

Liu, A., Yin, X., Shi, L., Li, P., Thornburg, K., Wang, R. & Rugonyi, S., Jul 23 2012, In : PLoS One. 7, 7, e40869.

Research output: Contribution to journalArticle

Biomechanics
Optical tomography
tomography
Optical Coherence Tomography
Biomechanical Phenomena
184 Citations (Scopus)

Chemotherapy response and recurrence-free survival in Neoadjuvant breast cancer depends on biomarker profiles: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)

Esserman, L. J., Berry, D. A., Cheang, M. C. U., Yau, C., Perou, C. M., Carey, L., De Michele, A., Gray, J., Conway-Dorsey, K., Lenburg, M. E., Buxton, M. B., Davis, S. E., Van't Veer, L. J., Hudis, C., Chin, K-Y., Wolf, D., Krontiras, H., Montgomery, L., Tripathy, D., Lehman, C. & 14 others, Liu, M. C., Olopade, O. I., Rugo, H. S., Carpenter, J. T., Livasy, C., Dressler, L., Chhieng, D., Singh, B., Mies, C., Rabban, J., Chen, Y. Y., Giri, D., Au, A. & Hylton, N., Apr 2012, In : Breast Cancer Research and Treatment. 132, 3, p. 1049-1062 14 p.

Research output: Contribution to journalArticle

Biomarkers
Breast Neoplasms
Recurrence
Drug Therapy
Survival
42 Citations (Scopus)

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

Daemen, A., Wolf, D. M., Korkola, J., Griffith, O. L., Frankum, J. R., Brough, R., Jakkula, L. R., Wang, N. J., Natrajan, R., Reis-Filho, J. S., Lord, C. J., Ashworth, A., Spellman, P., Gray, J. & Van'T Veer, L. J., Sep 2012, In : Breast Cancer Research and Treatment. 135, 2, p. 505-517 13 p.

Research output: Contribution to journalArticle

DNA Repair
Cell Line
Genes
Breast Neoplasms
BRCA1 Gene
11 Citations (Scopus)

Development and evaluation of a portable audiometer for high-frequency screening of hearing loss from ototoxicity in homes/clinics

Jacobs, P., Silaski, G., Wilmington, D., Gordon, S., Helt, W., McMillan, G., Fausti, S. A. & Dille, M., 2012, In : IEEE Transactions on Biomedical Engineering. 59, 12 PART2, p. 3097-3103 7 p., 6237516.

Research output: Contribution to journalArticle

Audiometers
Audition
Screening
Oncology
Drug dosage
17 Citations (Scopus)

Development of a label-free imaging technique for the quantification of thrombus formation

Baker, S. M., Phillips, K. G. & McCarty, O., Dec 2012, In : Cellular and Molecular Bioengineering. 5, 4, p. 488-492 5 p.

Research output: Contribution to journalArticle

Platelets
Quantification
Labels
Thrombosis
Imaging
12 Citations (Scopus)

Development of coagulation factor probes for the identification of procoagulant circulating tumor cells

Tormoen, G. W., Cianchetti, F. A., Bock, P. E. & McCarty, O., 2012, In : Frontiers in Oncology. 2 SEP, Article 110.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Blood Coagulation Factors
Neoplasms
Cell Line
Factor VIIa
19 Citations (Scopus)

Do circulating tumor cells play a role in coagulation and thrombosis?

Tormoen, G. W., Haley, K., Levine, R. L. & McCarty, O., 2012, In : Frontiers in Oncology. 2 SEP, Article 115.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Thrombosis
Neoplasms
Anticoagulants
Thrombophilia
17 Citations (Scopus)

Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer

Mukhtar, R. A., Moore, A. P., Tandon, V. J., Nseyo, O., Twomey, P., Adisa, C. A., Eleweke, N., Au, A., Baehner, F. L., Moore, D. H., McGrath, M. S., Olopade, O. I., Gray, J., Campbell, M. J. & Esserman, L. J., Nov 2012, In : Annals of Surgical Oncology. 19, 12, p. 3979-3986 8 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
Macrophages
Breast Neoplasms
Neoplasms
Hormones
67 Citations (Scopus)

Enhanced optical clearing of skin in vivo and optical coherence tomography in-depth imaging

Wen, X., Jacques, S., Tuchin, V. V. & Zhu, D., Jun 2012, In : Journal of Biomedical Optics. 17, 6, 066022.

Research output: Contribution to journalArticle

clearing
Optical tomography
Skin
tomography
Imaging techniques
22 Citations (Scopus)

Extracellular matrix production and regulation in micropatterned endothelial cells

Anderson, D. E. J. & Hinds, M., Oct 12 2012, In : Biochemical and Biophysical Research Communications. 427, 1, p. 159-164 6 p.

Research output: Contribution to journalArticle

Endothelial cells
Extracellular Matrix
Collagen
Fibronectins
Endothelial Cells
11 Citations (Scopus)
embryos
Optical tomography
tomography
Tissue
Imaging techniques
18 Citations (Scopus)

Factor xi-deficient mice display reduced inflammation, coagulopathy, and bacterial growth during listeriosis

Luo, D., Szaba, F. M., Kummer, L. W., Johnson, L. L., Tucker, E., Gruber, A., Gailani, D. & Smiley, S. T., Jan 2012, In : Infection and Immunity. 80, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

Listeriosis
Factor XI
Fibrin
Listeria monocytogenes
Inflammation
43 Citations (Scopus)

Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry

Subhash, H. M., Nguyen-Huynh, A., Wang, R. K., Jacques, S., Choudhury, N. & Nuttall, A., Jun 2012, In : Journal of Biomedical Optics. 17, 6, 060505.

Research output: Contribution to journalArticle

middle ear
Optical tomography
Demonstrations
tomography
Acoustics
28 Citations (Scopus)

Fluid shear stress alters the hemostatic properties of endothelial outgrowth cells

Ensley, A. E., Nerem, R. M., Anderson, D. E. J., Hanson, S. R. & Hinds, M., Jan 1 2012, In : Tissue Engineering - Part A. 18, 1-2, p. 127-136 10 p.

Research output: Contribution to journalArticle

Hemostatics
Shear stress
Endothelial Cells
Fluids
Proteins