• 7162 Citations
  • 49 h-Index
1984 …2020
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Research Output 1985 2019

2019
3 Citations (Scopus)

Apnea-hypopnea event duration predicts mortality in men and women in the sleep heart health study

Butler, M., Emch, J. T., Rueschman, M., Sands, S. A., Shea, S., Wellman, A. & Redline, S., Apr 1 2019, In : American journal of respiratory and critical care medicine. 199, 7, p. 903-912 10 p.

Research output: Contribution to journalArticle

Apnea
Sleep
Arousal
Mortality
Sleep Apnea Syndromes

Circadian Rhythm of Vascular Function in Midlife Adults

Thosar, S. S., Berman, A. M., Herzig, M. X., McHill, A. W., Bowles, N. P., Swanson, C. M., Clemons, N. A., Butler, M., Clemons, A. A., Emens, J. & Shea, S., Jun 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 6, p. 1203-1211 9 p.

Research output: Contribution to journalArticle

Open Access
Circadian Rhythm
Blood Vessels
Sleep
Endothelin-1
Malondialdehyde

Correction to: Chronotherapy for Hypertension (Current Hypertension Reports, (2018), 20, 11, (97), 10.1007/s11906-018-0897-4)

Bowles, N. P., Thosar, S. S., Herzig, M. X. & Shea, S., Jan 1 2019, In : Current Hypertension Reports. 21, 1, 1.

Research output: Contribution to journalComment/debate

Chronotherapy
Chronic Renal Insufficiency
Meta-Analysis
Hypertension
Obstructive Sleep Apnea

Impact of mental stress, the circadian system and their interaction on human cardiovascular function

Scheer, F. A. J. L., Chellappa, S. L., Hu, K. & Shea, S., May 1 2019, In : Psychoneuroendocrinology. 103, p. 125-129 5 p.

Research output: Contribution to journalArticle

Heart Rate
Cardiovascular System
Epinephrine
Catecholamines
Hemodynamics

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans

Thosar, S. S., Rueda, J., Berman, A. M., Lasarev, M. R., Herzig, M. X., Clemons, N. A., Roberts, S. A., Bowles, N. P., Emens, J., Ellison, D. & Shea, S., Feb 1 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 2, p. R157-R164

Research output: Contribution to journalArticle

Aldosterone
Sleep
Wakefulness
Healthy Volunteers
Exercise
2018
2 Citations (Scopus)

Chronotherapy for Hypertension

Bowles, N. P., Thosar, S. S., Herzig, M. X. & Shea, S., Nov 1 2018, In : Current Hypertension Reports. 20, 11, 97.

Research output: Contribution to journalReview article

Chronotherapy
Blood Pressure
Hypertension
Antihypertensive Agents
Drug Design
1 Citation (Scopus)

Fractal regulation and incident Alzheimer's disease in elderly individuals

Li, P., Yu, L., Lim, A. S. P., Buchman, A. S., Scheer, F. A. J. L., Shea, S., Schneider, J. A., Bennett, D. A. & Hu, K., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Fractals
Alzheimer Disease
Motor Activity
Sleep Deprivation
Cognition
3 Citations (Scopus)

Lowest perceived exertion in the late morning due to effects of the endogenous circadian system

Thosar, S. S., Herzig, M. X., Roberts, S. A., Berman, A. M., Clemons, N. A., McHill, A. W., Bowles, N. P., Morimoto, M., Butler, M., Emens, J. & Shea, S., Feb 23 2018, (Accepted/In press) In : British Journal of Sports Medicine.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Morning impairment in vascular function is unrelated to overnight sleep or the inactivity that accompanies sleep

Thosar, S. S., Berman, A. M., Herzig, M. X., Roberts, S. A., Lasarev, M. R. & Shea, S., Nov 27 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 5, p. R986-R993

Research output: Contribution to journalArticle

Blood Vessels
Sleep
Endothelin-1
Malondialdehyde
Dilatation

Predictors of obtaining polysomnography among otolaryngologists prior to adenotonsillectomy for childhood sleep-disordered breathing

Lam, D., Shea, S., Weaver, E. M. & Mitchell, R. B., Aug 15 2018, In : Journal of Clinical Sleep Medicine. 14, 8, p. 1361-1367 7 p.

Research output: Contribution to journalArticle

Polysomnography
Sleep Apnea Syndromes
Otolaryngology
Neck
Head

Resident physician extended work hours and burnout

McHill, A. W., Czeisler, C. A. & Shea, S., Aug 1 2018, In : Sleep. 41, 8

Research output: Contribution to journalEditorial

Physicians
20 Citations (Scopus)

Role of the circadian system in cardiovascular disease

Thosar, S. S., Butler, M. & Shea, S., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2157-2167 11 p.

Research output: Contribution to journalReview article

Circadian Rhythm
Cardiovascular Diseases
Activity Cycles
Circadian Clocks
Autonomic Nervous System

Sleep & work, work & sleep

Buxton, O. M. & Shea, S., Dec 1 2018, In : Sleep Health. 4, 6, p. 497-498 2 p.

Research output: Contribution to journalEditorial

Sleep

Sleep disturbance after pediatric traumatic brain injury: Critical knowledge gaps remain for the critically injured

Williams, C. N., Lim, M. & Shea, S., Jan 1 2018, In : Nature and Science of Sleep. 10, p. 225-228 4 p.

Research output: Contribution to journalEditorial

Sleep
Pediatrics
Traumatic Brain Injury
6 Citations (Scopus)

The importance of the circadian system & sleep for bone health

Swanson, C. M., Kohrt, W. M., Buxton, O. M., Everson, C. A., Wright, K. P., Orwoll, E. & Shea, S., Jan 1 2018, (Accepted/In press) In : Metabolism: Clinical and Experimental.

Research output: Contribution to journalArticle

Sleep
Bone and Bones
Health
Biological Phenomena
Circadian Clocks
2017
4 Citations (Scopus)

24-hour profile of serum sclerostin and its association with bone biomarkers in men

Swanson, C., Shea, S., Wolfe, P., Markwardt, S., Cain, S. W., Munch, M., Czeisler, C. A., Orwoll, E. & Buxton, O. M., Jul 26 2017, (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Contribution to journalArticle

Osteocytes
Periodicity
Bone Remodeling
Biomarkers
Bone and Bones
9 Citations (Scopus)

Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans

Swanson, C. M., Shea, S., Wolfe, P., Cain, S. W., Munch, M., Vujovic, N., Czeisler, C. A., Buxton, O. M. & Orwoll, E., Oct 1 2017, In : The Journal of clinical endocrinology and metabolism. 102, 10, p. 3722-3730 9 p.

Research output: Contribution to journalArticle

Bone Remodeling
Sleep
Bone
Bone and Bones
Biomarkers
1 Citation (Scopus)

Recent legalization of cannabis use: Effects on sleep, health, and workplace safety

Bowles, N. P., Herzig, M. X. & Shea, S., Jan 1 2017, In : Nature and Science of Sleep. 9, p. 249-251 3 p.

Research output: Contribution to journalEditorial

Cannabis
Workplace
Sleep
Safety
Health
2016
1 Citation (Scopus)

A growth spurt in pediatric sleep research

Lam, D. & Shea, S., 2016, In : Nature and Science of Sleep. 8, p. 133-135 3 p.

Research output: Contribution to journalReview article

Sleep
Pediatrics
Growth
Research

Are we underestimating the lifelong benefits of therapy for obstructive sleep apnea?

Berman, A. M., Thosar, S. S. & Shea, S., 2016, In : Nature and Science of Sleep. 8, p. 87-89 3 p.

Research output: Contribution to journalEditorial

Obstructive Sleep Apnea
Therapeutics
12 Citations (Scopus)

Assessment of pediatric obstructive sleep apnea using a drug-induced sleep endoscopy rating scale

Lam, D., Weaver, E. M., Macarthur, C., Milczuk, H., O'Neill, E., Smith, T., Nguyen, T. & Shea, S., 2016, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Endoscopy
Sleep
Pediatrics
Pharmaceutical Preparations
1 Citation (Scopus)

ATS core curriculum 2016: Part I. adult sleep medicine

Balachandran, J. S., Thomson, C. C., Sumter, D. B., Shelgikar, A. V., Lachapelle, P., Pamidi, S., Fall, M., Lal, C., Baba, R. Y., Shah, N., Fields, B. G., Sarmiento, K., Butler, M., Shea, S., Baptiste, J. V., Sharkey, K. M. & Wang, T., Apr 1 2016, In : Annals of the American Thoracic Society. 13, 4, p. 549-561 13 p.

Research output: Contribution to journalArticle

Chronobiology Disorders
Circadian Rhythm Sleep Disorders
Parasomnias
Polysomnography
Medical Societies
11 Citations (Scopus)

Circadian gene variants influence sleep and the sleep electroencephalogram in humans

Chang, A. M., Bjonnes, A. C., Aeschbach, D., Buxton, O. M., Gooley, J. J., Anderson, C., Van Reen, E., Cain, S. W., Czeisler, C. A., Duffy, J. F., Lockley, S. W., Shea, S., Scheer, F. A. J. L. & Saxena, R., May 27 2016, In : Chronobiology International. 33, 5, p. 561-573 13 p.

Research output: Contribution to journalArticle

Electroencephalography
Sleep
Genes
REM Sleep
Melatonin MT2 Receptor
31 Citations (Scopus)

Impact of common diabetes risk variant in MTNR1B on sleep, circadian, and melatonin physiology

Lane, J. M., Chang, A. M., Bjonnes, A. C., Aeschbach, D., Anderson, C., Cade, B. E., Cain, S. W., Czeisler, C. A., Gharib, S. A., Gooley, J. J., Gottlieb, D. J., Grant, S. F. A., Klerman, E. B., Lauderdale, D. S., Lockley, S. W., Munch, M., Patel, S., Punjabi, N. M., Rajaratnam, S. M. W., Rueger, M. & 11 others, St. Hilaire, M. A., Santhi, N., Scheuermaier, K., Van Reen, E., Zee, P. C., Shea, S., Duffy, J. F., Buxton, O. M., Redline, S., Scheer, F. A. J. L. & Saxena, R., Jun 1 2016, In : Diabetes. 65, 6, p. 1741-1751 11 p.

Research output: Contribution to journalArticle

Melatonin
Sleep
Alleles
Actigraphy
Type 2 Diabetes Mellitus
9 Citations (Scopus)

Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results from a 3.5-Year, Longitudinal Randomized Controlled Trial

Hu, K., Riemersma-Van Der Lek, R. F., Patxot, M., Li, P., Shea, S., Scheer, F. A. J. L. & Van Someren, E. J. W., Jun 13 2016, In : Scientific Reports. 6, 27742.

Research output: Contribution to journalArticle

Dementia
Randomized Controlled Trials
Exercise
Melatonin
Depression
2015
1 Citation (Scopus)

Brachial artery endothelial function is stable across the morning in young men

Thosar, S. S., Wiggins, C. C., Shea, S. & Wallace, J. P., Dec 1 2015, In : Cardiovascular Ultrasound. 13, 1, 36.

Research output: Contribution to journalArticle

Brachial Artery
Blood Vessels
Circadian Rhythm
Dilatation
Sleep
26 Citations (Scopus)

Endogenous circadian regulation of pro-inflammatory cytokines and chemokines in the presence of bacterial lipopolysaccharide in humans

Rahman, S. A., Castanon-Cervantes, O., Scheer, F. A. J. L., Shea, S., Czeisler, C. A., Davidson, A. J. & Lockley, S. W., Jul 1 2015, In : Brain, Behavior, and Immunity. 47, p. 4-13 10 p.

Research output: Contribution to journalArticle

Chemokines
Lipopolysaccharides
Immunologic Factors
Cytokines
Sleep
107 Citations (Scopus)

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

Morris, C. J., Yang, J. N., Garcia, J. I., Myers, S., Bozzi, I., Wang, W., Buxton, O. M., Shea, S. & Scheer, F. A. J. L., Apr 28 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 17, p. E2225-E2234

Research output: Contribution to journalArticle

Glucose
Insulin
Sleep
Insulin Resistance
Fasting
36 Citations (Scopus)

Obstructive sleep apnea and metabolic bone disease: Insights into the relationship between bone and sleep

Swanson, C. M., Shea, S., Stone, K. L., Cauley, J. A., Rosen, C. J., Redline, S., Karsenty, G. & Orwoll, E., Feb 1 2015, In : Journal of Bone and Mineral Research. 30, 2, p. 199-211 13 p.

Research output: Contribution to journalArticle

Metabolic Bone Diseases
Obstructive Sleep Apnea
Sleep
Bone and Bones
Sleep Apnea Syndromes
13 Citations (Scopus)

The circadian system contributes to apnea lengthening across the night in obstructive sleep apnea

Butler, M., Smales, C., Wu, H., Hussain, M. V., Mohamed, Y. A., Morimoto, M. & Shea, S., Nov 1 2015, In : Sleep. 38, 11, p. 1793-1801 9 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Apnea
Sleep
Sleep Apnea Syndromes
Inpatients
2014
55 Citations (Scopus)

Human circadian system causes a morning peak in prothrombotic plasminogen activator inhibitor-1 (PAI-1) independent of the sleep/wake cycle

Scheer, F. A. J. L. & Shea, S., Jan 23 2014, In : Blood. 123, 4, p. 590-593 4 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Sleep
Exercise
Fibrinolysis
Circadian Rhythm
14 Citations (Scopus)

Simulated shift work in rats perturbs multiscale regulation of locomotor activity

Hsieh, W. H., Escobar, C., Yugay, T., Lo, M. T., Pittman-Polletta, B., Salgado-Delgado, R., Scheer, F. A. J. L., Shea, S., Buijs, R. M. & Hu, K., Jul 6 2014, In : Journal of the Royal Society Interface. 11, 96, 20140318.

Research output: Contribution to journalArticle

Locomotion
Fractals
Suprachiasmatic Nucleus
Rats
Animals
2013
24 Citations (Scopus)

Evaluation of a single-channel nasal pressure device to assess obstructive sleep apnea risk in laboratory and home environments

Crowley, K. E., Rajaratnam, S. M. W., Shea, S., Epstein, L. J., Czeisler, C. A. & Lockley, S. W., 2013, In : Journal of Clinical Sleep Medicine. 9, 2, p. 109-116 8 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Apnea
Nose
Pressure
Equipment and Supplies
24 Citations (Scopus)

Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia

Hu, K., Harper, D. G., Shea, S., Stopa, E. G. & Scheer, F. A. J. L., Jul 18 2013, In : Scientific Reports. 3, 2229.

Research output: Contribution to journalArticle

Fractals
Neurotransmitter Agents
Dementia
Biomarkers
Suprachiasmatic Nucleus
67 Citations (Scopus)

The internal circadian clock increases hunger and appetite in the evening independent of food intake and other behaviors

Scheer, F. A. J. L., Morris, C. J. & Shea, S., Mar 2013, In : Obesity. 21, 3, p. 421-423 3 p.

Research output: Contribution to journalArticle

Circadian Clocks
Hunger
Appetite
Sleep
Eating
28 Citations (Scopus)

The role of the circadian system in fractal neurophysiological control

Pittman-Polletta, B. R., Scheer, F. A. J. L., Butler, M., Shea, S. & Hu, K., Nov 2013, In : Biological Reviews. 88, 4, p. 873-894 22 p.

Research output: Contribution to journalArticle

Fractals
heart rate
physiology
health information
neurophysiology
2012
346 Citations (Scopus)

Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

Buxton, O. M., Cain, S. W., O'Connor, S. P., Porter, J. H., Duffy, J. F., Wang, W., Czeisler, C. A. & Shea, S., Apr 11 2012, In : Science Translational Medicine. 4, 129, 129ra43.

Research output: Contribution to journalArticle

Sleep
Glucose
Basal Metabolism
Meals
Epidemiologic Studies
167 Citations (Scopus)

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

Jeyaraj, D., Haldar, S. M., Wan, X., McCauley, M. D., Ripperger, J. A., Hu, K., Lu, Y., Eapen, B. L., Sharma, N., Ficker, E., Cutler, M. J., Gulick, J., Sanbe, A., Robbins, J., Demolombe, S., Kondratov, R. V., Shea, S., Albrecht, U., Wehrens, X. H. T., Rosenbaum, D. S. & 1 others, Jain, M. K., Mar 1 2012, In : Nature. 483, 7387, p. 96-101 6 p.

Research output: Contribution to journalArticle

Circadian Rhythm
Cardiac Arrhythmias
Ion Channels
Kv Channel-Interacting Proteins
Brugada Syndrome
24 Citations (Scopus)

Fractal Patterns of Neural Activity Exist within the Suprachiasmatic Nucleus and Require Extrinsic Network Interactions

Hu, K., Meijer, J. H., Shea, S., vanderLeest, H. T., Pittman-Polletta, B., Houben, T., van Oosterhout, F., Deboer, T. & Scheer, F. A. J. L., 2012, In : PLoS One. 7, 11, e48927.

Research output: Contribution to journalArticle

Fractals
Suprachiasmatic Nucleus
heart rate
neural networks
rodents
54 Citations (Scopus)

Klf15 orchestrates circadian nitrogen homeostasis

Jeyaraj, D., Scheer, F. A. J. L., Ripperger, J. A., Haldar, S. M., Lu, Y., Prosdocimo, D. A., Eapen, S. J., Eapen, B. L., Cui, Y., Mahabeleshwar, G. H., Lee, H. G., Smith, M. A., Casadesus, G., Mintz, E. M., Sun, H., Wang, Y., Ramsey, K. M., Bass, J., Shea, S., Albrecht, U. & 1 others, Jain, M. K., Mar 7 2012, In : Cell Metabolism. 15, 3, p. 311-323 13 p.

Research output: Contribution to journalArticle

Homeostasis
Nitrogen
Periodicity
Cues
Circadian Clocks
12 Citations (Scopus)

Obesity and pharmacologic control of the body clock

Shea, S., Jul 12 2012, In : New England Journal of Medicine. 367, 2, p. 175-178 4 p.

Research output: Contribution to journalArticle

Obesity
43 Citations (Scopus)

Repeated melatonin supplementation improves sleep in hypertensive patients treated with beta-blockers: A randomized controlled trial

Scheer, F. A. J. L., Morris, C. J., Garcia, J. I., Smales, C., Kelly, E. E., Marks, J., Malhotra, A. & Shea, S., Oct 1 2012, In : Sleep. 35, 10, p. 1395-1402 8 p.

Research output: Contribution to journalArticle

Melatonin
Sleep
Randomized Controlled Trials
Placebos
Sleep Stages
2011
39 Citations (Scopus)

Endogenous circadian rhythm in vasovagal response to head-up tilt

Hu, K., Scheer, F. A. J. L., Laker, M., Smales, C. & Shea, S., Mar 8 2011, In : Circulation. 123, 9, p. 961-970 10 p.

Research output: Contribution to journalArticle

Syncope
Circadian Rhythm
Head
Cardiovascular System
Sleep
66 Citations (Scopus)

Existence of an endogenous circadian blood pressure rhythm in humans that peaks in the evening

Shea, S., Hilton, M. F., Hu, K. & Scheer, F. A. J. L., Apr 15 2011, In : Circulation Research. 108, 8, p. 980-984 5 p.

Research output: Contribution to journalArticle

Blood Pressure
Sleep
Circadian Rhythm
Wakefulness
Body Temperature

Health disparities in sleep medicine: Responses to the American Sleep Medicine Foundation humanitarian projects award program

Wise, M. S., Morgenthaler, T., Badr, S., Gruber, R., Redline, S. & Shea, S., 2011, In : Journal of Clinical Sleep Medicine. 7, 6, p. 583-584 2 p.

Research output: Contribution to journalArticle

Sleep Medicine Specialty
Healthcare Disparities
Altruism
Program Development
Medical Societies

Response to letter regarding article, endogenous circadian rhythm in vasovagal response to head-up tilt

Hu, K., Scheer, F. A. J. L., Shea, S., Laker, M. & Smales, C., Sep 27 2011, In : Circulation. 124, 13

Research output: Contribution to journalArticle

145 Citations (Scopus)

Sleep disorders, health, and safety in police officers

Rajaratnam, S. M. W., Barger, L. K., Lockley, S. W., Shea, S., Wang, W., Landrigan, C. P., O'Brien, C. S., Qadri, S., Sullivan, J. P., Cade, B. E., Epstein, L. J., White, D. P. & Czeisler, C. A., Dec 21 2011, In : JAMA - Journal of the American Medical Association. 306, 23, p. 2567-2578 12 p.

Research output: Contribution to journalArticle

Police
Safety
Odds Ratio
Health
Obstructive Sleep Apnea
75 Citations (Scopus)

The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors

Scheer, F. A. J. L., Michelson, A. D., Frelinger, A. L., Evoniuk, H., Kelly, E. E., McCarthy, M., Doamekpor, L. A., Barnard, M. R. & Shea, S., Sep 8 2011, In : PLoS One. 6, 9, e24549.

Research output: Contribution to journalArticle

platelet activation
Platelet Activation
Platelets
circadian rhythm
Blood Platelets

The nature of sleep examined via the science of sleep

Hussain, M. V. & Shea, S., 2011, In : Nature and Science of Sleep. 3, p. 37-38 2 p.

Research output: Contribution to journalArticle

Sleep
3 Citations (Scopus)

Wake up to insomnia: Future approaches to the management of insomnia

Hussain, M. T. & Shea, S., 2011, In : Nature and Science of Sleep. 3, p. 33-35 3 p.

Research output: Contribution to journalArticle

Sleep Initiation and Maintenance Disorders