Research Output 1985 2017

  • 5961 Citations
  • 46 h-Index
  • 113 Article
  • 2 Conference contribution
  • 1 Editorial
  • 1 Review article
2017

24-hour profile of serum sclerostin and its association with bone biomarkers in men

Swanson, C., Shea, S. A., Wolfe, P., Markwardt, S., Cain, S. W., Munch, M., Czeisler, C. A., Orwoll, E. S. & Buxton, O. M. Jul 26 2017 (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Osteocytes
Biomarkers
Bone and Bones
Serum
Periodicity
1 Citations

Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans

Swanson, C. M., Shea, S. A., Wolfe, P., Cain, S. W., Munch, M., Vujovic, N., Czeisler, C. A., Buxton, O. M. & Orwoll, E. S. Oct 1 2017 In : The Journal of clinical endocrinology and metabolism. 102, 10, p. 3722-3730 9 p.

Research output: Research - peer-reviewArticle

Bone Remodeling
Sleep
Bone and Bones
Bone
Biomarkers
2016

A growth spurt in pediatric sleep research

Lam, D. J. & Shea, S. A. 2016 In : Nature and Science of Sleep. 8, p. 133-135 3 p.

Research output: Research - peer-reviewReview article

Are we underestimating the lifelong benefits of therapy for obstructive sleep apnea?

Berman, A. M., Thosar, S. S. & Shea, S. A. 2016 In : Nature and Science of Sleep. 8, p. 87-89 3 p.

Research output: Research - peer-reviewEditorial

7 Citations
Obstructive Sleep Apnea
Endoscopy
Sleep
Pediatrics
Pharmaceutical Preparations
1 Citations

ATS core curriculum 2016: Part I. adult sleep medicine

Balachandran, J. S., Thomson, C. C., Sumter, D. B., Shelgikar, A. V., Lachapelle, P., Pamidi, S., Fall, M., Lal, C., Baba, R. Y., Shah, N., Fields, B. G., Sarmiento, K., Butler, M. P., Shea, S. A., Baptiste, J. V., Sharkey, K. M. & Wang, T. Apr 1 2016 In : Annals of the American Thoracic Society. 13, 4, p. 549-561 13 p.

Research output: Research - peer-reviewArticle

3 Citations

Circadian gene variants influence sleep and the sleep electroencephalogram in humans

Chang, A. M., Bjonnes, A. C., Aeschbach, D., Buxton, O. M., Gooley, J. J., Anderson, C., Van Reen, E., Cain, S. W., Czeisler, C. A., Duffy, J. F., Lockley, S. W., Shea, S. A., Scheer, F. A. J. L. & Saxena, R. May 27 2016 In : Chronobiology International. 33, 5, p. 561-573 13 p.

Research output: Research - peer-reviewArticle

Electroencephalography
Sleep
Genes
REM Sleep
Alleles
10 Citations

Impact of common diabetes risk variant in MTNR1B on sleep, circadian, and melatonin physiology

Lane, J. M. , Chang, A. M. , Bjonnes, A. C. , Aeschbach, D. , Anderson, C. , Cade, B. E. , Cain, S. W. , Czeisler, C. A. , Gharib, S. A. , Gooley, J. J. , Gottlieb, D. J. , Grant, S. F. A. , Klerman, E. B. , Lauderdale, D. S. , Lockley, S. W. , Munch, M. , Patel, S. , Punjabi, N. M. , Rajaratnam, S. M. W. , Rueger, M. & 11 others St. Hilaire, M. A., Santhi, N., Scheuermaier, K., Van Reen, E., Zee, P. C., Shea, S. A., Duffy, J. F., Buxton, O. M., Redline, S., Scheer, F. A. J. L. & Saxena, R. Jun 1 2016 In : Diabetes. 65, 6, p. 1741-1751 11 p.

Research output: Research - peer-reviewArticle

Melatonin
Sleep
Alleles
Type 2 Diabetes Mellitus
Actigraphy
1 Citations

Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results from a 3.5-Year, Longitudinal Randomized Controlled Trial

Hu, K., Riemersma-Van Der Lek, R. F., Patxot, M., Li, P., Shea, S. A., Scheer, F. A. J. L. & Van Someren, E. J. W. Jun 13 2016 In : Scientific Reports. 6, 27742

Research output: Research - peer-reviewArticle

Dementia
Randomized Controlled Trials
Exercise
Melatonin
Depression
2015

Brachial artery endothelial function is stable across the morning in young men

Thosar, S. S., Wiggins, C. C., Shea, S. A. & Wallace, J. P. Dec 1 2015 In : Cardiovascular Ultrasound. 13, 1, 36

Research output: Research - peer-reviewArticle

Brachial Artery
Blood Vessels
Circadian Rhythm
Dilatation
Sleep
16 Citations

Endogenous circadian regulation of pro-inflammatory cytokines and chemokines in the presence of bacterial lipopolysaccharide in humans

Rahman, S. A., Castanon-Cervantes, O., Scheer, F. A. J. L., Shea, S. A., Czeisler, C. A., Davidson, A. J. & Lockley, S. W. Jul 1 2015 In : Brain, Behavior, and Immunity. 47, p. 4-13 10 p.

Research output: Research - peer-reviewArticle

Chemokines
Lipopolysaccharides
Cytokines
Immunologic Factors
Sleep
54 Citations

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

Morris, C. J., Yang, J. N., Garcia, J. I., Myers, S., Bozzi, I., Wang, W., Buxton, O. M., Shea, S. A. & Scheer, F. A. J. L. Apr 28 2015 In : Proceedings of the National Academy of Sciences of the United States of America. 112, 17, p. E2225-E2234

Research output: Research - peer-reviewArticle

Glucose
Insulin
Sleep
Insulin-Secreting Cells
Insulin Resistance
13 Citations

Obstructive sleep apnea and metabolic bone disease: Insights into the relationship between bone and sleep

Swanson, C. M., Shea, S. A., Stone, K. L., Cauley, J. A., Rosen, C. J., Redline, S., Karsenty, G. & Orwoll, E. S. Feb 1 2015 In : Journal of Bone and Mineral Research. 30, 2, p. 199-211 13 p.

Research output: Research - peer-reviewArticle

Metabolic Bone Diseases
Obstructive Sleep Apnea
Sleep
Bone and Bones
Sleep Apnea Syndromes
8 Citations

The circadian system contributes to apnea lengthening across the night in obstructive sleep apnea

Butler, M. P., Smales, C., Wu, H., Hussain, M. V., Mohamed, Y. A., Morimoto, M. & Shea, S. A. Nov 1 2015 In : Sleep. 38, 11, p. 1793-1801 9 p.

Research output: Research - peer-reviewArticle

Obstructive Sleep Apnea
Apnea
Sleep
Sleep Apnea Syndromes
Inpatients
2014
34 Citations

Human circadian system causes a morning peak in prothrombotic plasminogen activator inhibitor-1 (PAI-1) independent of the sleep/wake cycle

Scheer, F. A. J. L. & Shea, S. A. Jan 23 2014 In : Blood. 123, 4, p. 590-593 4 p.

Research output: Research - peer-reviewArticle

Plasminogen Activator Inhibitor 1
Sleep
Exercise
Fibrinolysis
Circadian Rhythm
11 Citations

Simulated shift work in rats perturbs multiscale regulation of locomotor activity

Hsieh, W. H., Escobar, C., Yugay, T., Lo, M. T., Pittman-Polletta, B., Salgado-Delgado, R., Scheer, F. A. J. L., Shea, S. A., Buijs, R. M. & Hu, K. Jul 6 2014 In : Journal of the Royal Society Interface. 11, 96, 20140318

Research output: Research - peer-reviewArticle

Locomotion
Rats
Animals
Fractals
Suprachiasmatic Nucleus
2013
16 Citations

Evaluation of a single-channel nasal pressure device to assess obstructive sleep apnea risk in laboratory and home environments

Crowley, K. E., Rajaratnam, S. M. W., Shea, S. A., Epstein, L. J., Czeisler, C. A. & Lockley, S. W. 2013 In : Journal of Clinical Sleep Medicine. 9, 2, p. 109-116 8 p.

Research output: Research - peer-reviewArticle

Obstructive Sleep Apnea
Apnea
Nose
Pressure
Equipment and Supplies
16 Citations

Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia

Hu, K., Harper, D. G., Shea, S. A., Stopa, E. G. & Scheer, F. A. J. L. Jul 18 2013 In : Scientific Reports. 3, 2229

Research output: Research - peer-reviewArticle

Fractals
Neurotransmitter Agents
Dementia
Biomarkers
Suprachiasmatic Nucleus
37 Citations

The internal circadian clock increases hunger and appetite in the evening independent of food intake and other behaviors

Scheer, F. A. J. L., Morris, C. J. & Shea, S. A. Mar 2013 In : Obesity. 21, 3, p. 421-423 3 p.

Research output: Research - peer-reviewArticle

Circadian Clocks
Hunger
Appetite
Sleep
Eating
17 Citations

The role of the circadian system in fractal neurophysiological control

Pittman-Polletta, B. R., Scheer, F. A. J. L., Butler, M. P., Shea, S. A. & Hu, K. Nov 2013 In : Biological Reviews. 88, 4, p. 873-894 22 p.

Research output: Research - peer-reviewArticle

heart rate
physiology
Fractals
health information
neurophysiology
2012
246 Citations

Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

Buxton, O. M., Cain, S. W., O'Connor, S. P., Porter, J. H., Duffy, J. F., Wang, W., Czeisler, C. A. & Shea, S. A. Apr 11 2012 In : Science Translational Medicine. 4, 129, 129ra43

Research output: Research - peer-reviewArticle

Sleep
Glucose
Basal Metabolism
Meals
Epidemiologic Studies
139 Citations

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

Jeyaraj, D. , Haldar, S. M. , Wan, X. , McCauley, M. D. , Ripperger, J. A. , Hu, K. , Lu, Y. , Eapen, B. L. , Sharma, N. , Ficker, E. , Cutler, M. J. , Gulick, J. , Sanbe, A. , Robbins, J. , Demolombe, S. , Kondratov, R. V. , Shea, S. A. , Albrecht, U. , Wehrens, X. H. T. , Rosenbaum, D. S. & 1 others Jain, M. K. Mar 1 2012 In : Nature. 483, 7387, p. 96-101 6 p.

Research output: Research - peer-reviewArticle

Kruppel-Like Transcription Factors
Circadian Rhythm
Cardiac Arrhythmias
Ion Channels
Kv Channel-Interacting Proteins
20 Citations

Fractal Patterns of Neural Activity Exist within the Suprachiasmatic Nucleus and Require Extrinsic Network Interactions

Hu, K., Meijer, J. H., Shea, S. A., vanderLeest, H. T., Pittman-Polletta, B., Houben, T., van Oosterhout, F., Deboer, T. & Scheer, F. A. J. L. 2012 In : PLoS One. 7, 11, e48927

Research output: Research - peer-reviewArticle

Fractals
Suprachiasmatic Nucleus
heart rate
neural networks
rodents
38 Citations

Klf15 orchestrates circadian nitrogen homeostasis

Jeyaraj, D. , Scheer, F. A. J. L. , Ripperger, J. A. , Haldar, S. M. , Lu, Y. , Prosdocimo, D. A. , Eapen, S. J. , Eapen, B. L. , Cui, Y. , Mahabeleshwar, G. H. , Lee, H. G. , Smith, M. A. , Casadesus, G. , Mintz, E. M. , Sun, H. , Wang, Y. , Ramsey, K. M. , Bass, J. , Shea, S. A. , Albrecht, U. & 1 others Jain, M. K. Mar 7 2012 In : Cell Metabolism. 15, 3, p. 311-323 13 p.

Research output: Research - peer-reviewArticle

Homeostasis
Nitrogen
Kruppel-Like Transcription Factors
Periodicity
Cues
11 Citations

Obesity and pharmacologic control of the body clock

Shea, S. A. Jul 12 2012 In : New England Journal of Medicine. 367, 2, p. 175-178 4 p.

Research output: Research - peer-reviewArticle

23 Citations

Repeated melatonin supplementation improves sleep in hypertensive patients treated with beta-blockers: A randomized controlled trial

Scheer, F. A. J. L., Morris, C. J., Garcia, J. I., Smales, C., Kelly, E. E., Marks, J., Malhotra, A. & Shea, S. A. Oct 1 2012 In : Sleep. 35, 10, p. 1395-1402 8 p.

Research output: Research - peer-reviewArticle

Melatonin
Sleep
Randomized Controlled Trials
Placebos
Sleep Stages
2011
31 Citations

Endogenous circadian rhythm in vasovagal response to head-up tilt

Hu, K., Scheer, F. A. J. L., Laker, M., Smales, C. & Shea, S. A. Mar 8 2011 In : Circulation. 123, 9, p. 961-970 10 p.

Research output: Research - peer-reviewArticle

Syncope
Circadian Rhythm
Head
Cardiovascular System
Sleep
52 Citations

Existence of an endogenous circadian blood pressure rhythm in humans that peaks in the evening

Shea, S. A., Hilton, M. F., Hu, K. & Scheer, F. A. J. L. Apr 15 2011 In : Circulation Research. 108, 8, p. 980-984 5 p.

Research output: Research - peer-reviewArticle

Blood Pressure
Sleep
Circadian Rhythm
Wakefulness
Body Temperature

Health disparities in sleep medicine: Responses to the American Sleep Medicine Foundation humanitarian projects award program

Wise, M. S., Morgenthaler, T., Badr, S., Gruber, R., Redline, S. & Shea, S. A. 2011 In : Journal of Clinical Sleep Medicine. 7, 6, p. 583-584 2 p.

Research output: Research - peer-reviewArticle

Response to letter regarding article, endogenous circadian rhythm in vasovagal response to head-up tilt

Hu, K., Scheer, F. A. J. L., Shea, S. A., Laker, M. & Smales, C. Sep 27 2011 In : Circulation. 124, 13

Research output: Research - peer-reviewArticle

106 Citations

Sleep disorders, health, and safety in police officers

Rajaratnam, S. M. W., Barger, L. K., Lockley, S. W., Shea, S. A., Wang, W., Landrigan, C. P., O'Brien, C. S., Qadri, S., Sullivan, J. P., Cade, B. E., Epstein, L. J., White, D. P. & Czeisler, C. A. Dec 21 2011 In : JAMA - Journal of the American Medical Association. 306, 23, p. 2567-2578 12 p.

Research output: Research - peer-reviewArticle

Police
Safety
Health
Sleep Wake Disorders
Odds Ratio
47 Citations

The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors

Scheer, F. A. J. L., Michelson, A. D., Frelinger, A. L., Evoniuk, H., Kelly, E. E., McCarthy, M., Doamekpor, L. A., Barnard, M. R. & Shea, S. A. Sep 8 2011 In : PLoS One. 6, 9, e24549

Research output: Research - peer-reviewArticle

platelet activation
circadian rhythm
Platelet Activation
Blood Platelets
Platelets

The nature of sleep examined via the science of sleep

Hussain, M. V. & Shea, S. A. 2011 In : Nature and Science of Sleep. 3, p. 37-38 2 p.

Research output: Research - peer-reviewArticle

3 Citations

Wake up to insomnia: Future approaches to the management of insomnia

Hussain, M. T. & Shea, S. A. 2011 In : Nature and Science of Sleep. 3, p. 33-35 3 p.

Research output: Research - peer-reviewArticle

2010
38 Citations

Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions

Scheer, F. A. J. L., Chan, J. L., Fargnoli, J., Chamberland, J., Arampatzi, K., Shea, S. A., Blackburn, G. L. & Mantzoros, C. S. Nov 2010 In : Diabetologia. 53, 11, p. 2401-2405 5 p.

Research output: Research - peer-reviewArticle

Adiponectin
Molecular Weight
Lipocalin-2
Sleep
Fasting
104 Citations

Impact of the human circadian system, exercise, and their interaction on cardiovascular function

Scheer, F. A. J. L., Hu, K., Evoniuk, H., Kelly, E. E., Malhotra, A., Hilton, M. F. & Shea, S. A. Nov 23 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 47, p. 20541-20546 6 p.

Research output: Research - peer-reviewArticle

Exercise
Catecholamines
PM 8
Hemostatics
Hemostasis
2009
753 Citations

Adverse metabolic and cardiovascular consequences of circadian misalignment

Scheer, F. A. J. L., Hilton, M. F., Mantzoros, C. S. & Shea, S. A. Mar 17 2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 11, p. 4453-4458 6 p.

Research output: Research - peer-reviewArticle

Sleep
Glucose
Leptin
Hydrocortisone
Obesity
35 Citations

Influence of the Circadian System on Disease Severity

Litinski, M., Scheer, F. A. J. L. & Shea, S. A. Jun 2009 In : Sleep Medicine Clinics. 4, 2, p. 143-163 21 p.

Research output: Research - peer-reviewArticle

Chronotherapy
Circadian Clocks
Temporal Lobe
Circadian Rhythm
Epilepsy
22 Citations

Is there a circadian variation of epileptiform abnormalities in idiopathic generalized epilepsy?

Pavlova, M. K., Shea, S. A., Scheer, F. A. J. L. & Bromfield, E. B. Nov 2009 In : Epilepsy and Behavior. 16, 3, p. 461-467 7 p.

Research output: Research - peer-reviewArticle

Sleep
Idiopathic Generalized Epilepsy
Generalized Epilepsy
Melatonin
Consciousness
70 Citations

Reduction of scale invariance of activity fluctuations with aging and Alzheimer's disease: Involvement of the circadian pacemaker

Hu, K., Van Someren, E. J. W., Shea, S. A. & Scheer, F. A. J. L. Feb 24 2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 8, p. 2490-2494 5 p.

Research output: Research - peer-reviewArticle

Alzheimer Disease
Suprachiasmatic Nucleus
Young Adult
2008
60 Citations

An endogenous circadian rhythm in sleep inertia results in greatest cognitive impairment upon awakening during the biological night

Scheer, F. A. J. L., Shea, T. J., Hilton, M. F. & Shea, S. A. Aug 2008 In : Journal of Biological Rhythms. 23, 4, p. 353-361 9 p.

Research output: Research - peer-reviewArticle

Circadian Rhythm
Sleep
Cognitive Dysfunction
sleep
circadian rhythm
66 Citations

Polysomnographic respiratory abnormalities in asymptomatic individuals

Pavlova, M. K., Duffy, J. F. & Shea, S. A. 2008 In : Sleep. 31, 2, p. 241-248 8 p.

Research output: Research - peer-reviewArticle

Healthy Volunteers
Sleep
Polysomnography
Physical Examination
Electrocardiography
16 Citations

The circadian pacemaker generates similar circadian rhythms in the fractal structure of heart rate in humans and rats

Hu, K., Scheer, F. A. J. L., Buijs, R. M. & Shea, S. A. Oct 2008 In : Cardiovascular Research. 80, 1, p. 62-68 7 p.

Research output: Research - peer-reviewArticle

Fractals
Circadian Rhythm
Heart Rate
Suprachiasmatic Nucleus
Activity Cycles
24 Citations

The endogenous circadian pacemaker imparts a scale-invariant pattern of heart rate fluctuations across time scales spanning minutes to 24 hours

Hu, K., Scheer, F. A. J. L., Buijs, R. M. & Shea, S. A. Jun 2008 In : Journal of Biological Rhythms. 23, 3, p. 265-273 9 p.

Research output: Research - peer-reviewArticle

physical models
cardiovascular diseases
heart rate
mammals
Heart Rate
2007
3 Citations

Decreased sleep in heart failure: Are medications to blame? [2]

Scheer, F. A. J. L., Stone, P. H. & Shea, S. A. May 28 2007 In : Archives of Internal Medicine. 167, 10, p. 1098-1099 2 p.

Research output: Research - peer-reviewArticle

52 Citations

Endogenous circadian rhythm in human motor activity uncoupled from circadian influences on cardiac dynamics

Ivanov, P. C., Hu, K., Hilton, M. F., Shea, S. A. & Stanley, H. E. Dec 26 2007 In : Proceedings of the National Academy of Sciences of the United States of America. 104, 52, p. 20702-20707 6 p.

Research output: Research - peer-reviewArticle

Circadian Rhythm
Human Activities
Motor Activity
Sleep
Heart Rate
48 Citations

The suprachiasmatic nucleus functions beyond circadian rhythm generation

Hu, K., Scheer, F. A. J. L., Ivanov, P. C., Buijs, R. M. & Shea, S. A. Nov 9 2007 In : Neuroscience. 149, 3, p. 508-517 10 p.

Research output: Research - peer-reviewArticle

Suprachiasmatic Nucleus
Circadian Rhythm
Periodicity
Locomotion
Human Activities
2006
49 Citations

Reduced sleep efficiency in cervical spinal cord injury; association with abolished night time melatonin secretion

Scheer, F. A. J. L., Zeitzer, J. M., Ayas, N. T., Brown, R., Czeisler, C. A. & Shea, S. A. Feb 2006 In : Spinal Cord. 44, 2, p. 78-81 4 p.

Research output: Research - peer-reviewArticle

Melatonin
Spinal Cord Injuries
Sleep
Cervical Cord
Thoracic Injuries
2005
138 Citations

Independent circadian and sleep/wake regulation of adipokines and glucose in humans

Shea, S. A., Hilton, M. F., Orlova, C., Timothy Ayers, R. & Mantzoros, C. S. May 2005 In : Journal of Clinical Endocrinology and Metabolism. 90, 5, p. 2537-2544 8 p.

Research output: Research - peer-reviewArticle

Adipokines
Leptin
Sleep
Glucose
Eating
2004
64 Citations

Day/night patterns of focal seizures

Pavlova, M. K., Shea, S. A. & Bromfield, E. B. Feb 2004 In : Epilepsy and Behavior. 5, 1, p. 44-49 6 p.

Research output: Research - peer-reviewArticle

Seizures
Temporal Lobe
Epilepsy
Video Recording
Electroencephalography