• 7793 Citations
  • 49 h-Index
1984 …2020

Research output per year

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Research Output

2020

Effects of obstructive sleep apnea on endogenous circadian rhythms assessed during relaxed wakefulness; an exploratory analysis

Butler, M. P., Thosar, S. S., Smales, C., DeYoung, P. N., Wu, H., Hussain, M. V., Morimoto, M., Hu, K., Scheer, F. A. J. L. & Shea, S. A., Jan 1 2020, (Accepted/In press) In : Chronobiology International.

Research output: Contribution to journalArticle

The circadian system modulates the rate of recovery of systolic blood pressure after exercise in humans

Qian, J., Scheer, F. A., Hu, K. & Shea, S. A., Apr 15 2020, In : Sleep. 43, 4

Research output: Contribution to journalArticle

2019

Apnea-hypopnea event duration predicts mortality in men and women in the sleep heart health study

Butler, M. P., Emch, J. T., Rueschman, M., Sands, S. A., Shea, S. A., Wellman, A. & Redline, S., Apr 1 2019, In : American journal of respiratory and critical care medicine. 199, 7, p. 903-912 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Circadian Rhythm of Vascular Function in Midlife Adults

Thosar, S. S., Berman, A. M., Herzig, M. X., McHill, A. W., Bowles, N. P., Swanson, C. M., Clemons, N. A., Butler, M., Clemons, A. A., Emens, J. & Shea, S., Jun 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 6, p. 1203-1211 9 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Correction to: Chronotherapy for Hypertension (Current Hypertension Reports, (2018), 20, 11, (97), 10.1007/s11906-018-0897-4)

Bowles, N. P., Thosar, S. S., Herzig, M. X. & Shea, S., Jan 1 2019, In : Current Hypertension Reports. 21, 1, 1.

Research output: Contribution to journalComment/debate

Impact of mental stress, the circadian system and their interaction on human cardiovascular function

Scheer, F. A. J. L., Chellappa, S. L., Hu, K. & Shea, S. A., May 2019, In : Psychoneuroendocrinology. 103, p. 125-129 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Rapid suppression of bone formation marker in response to sleep restriction and circadian disruption in men

Swanson, C. M., Kohrt, W. M., Wolfe, P., Wright, K. P., Shea, S. A., Cain, S. W., Munch, M., Vujović, N., Czeisler, C. A., Orwoll, E. S. & Buxton, O. M., Dec 1 2019, In : Osteoporosis International. 30, 12, p. 2485-2493 9 p.

Research output: Contribution to journalArticle

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans

Thosar, S. S., Rueda, J., Berman, A. M., Lasarev, M. R., Herzig, M. X., Clemons, N. A., Roberts, S. A., Bowles, N. P., Emens, J., Ellison, D. & Shea, S., Feb 1 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 2, p. R157-R164

Research output: Contribution to journalArticle

1 Scopus citations

Sleep-Wake Disturbances After Acquired Brain Injury in Children Surviving Critical Care

Williams, C. N., Hartman, M. E., McEvoy, C. T., Hall, T. A., Lim, M. M., Shea, S. A., Luther, M., Guilliams, K. P., Guerriero, R. M., Bosworth, C. C. & Piantino, J. A., Jan 1 2019, (Accepted/In press) In : Pediatric Neurology.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Chronotherapy for Hypertension

Bowles, N. P., Thosar, S. S., Herzig, M. X. & Shea, S. A., Nov 1 2018, In : Current Hypertension Reports. 20, 11, 97.

Research output: Contribution to journalReview article

11 Scopus citations

Fractal regulation and incident Alzheimer's disease in elderly individuals

Li, P., Yu, L., Lim, A. S. P., Buchman, A. S., Scheer, F. A. J. L., Shea, S., Schneider, J. A., Bennett, D. A. & Hu, K., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

8 Scopus citations

Lowest perceived exertion in the late morning due to effects of the endogenous circadian system

Thosar, S. S., Herzig, M. X., Roberts, S. A., Berman, A. M., Clemons, N. A., McHill, A. W., Bowles, N. P., Morimoto, M., Butler, M. P., Emens, J. S. & Shea, S. A., Aug 2018, In : British journal of sports medicine. 52, 15, p. 1011-1012 2 p.

Research output: Contribution to journalLetter

4 Scopus citations

Morning impairment in vascular function is unrelated to overnight sleep or the inactivity that accompanies sleep

Thosar, S. S., Berman, A. M., Herzig, M. X., Roberts, S. A., Lasarev, M. R. & Shea, S., Nov 27 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 5, p. R986-R993

Research output: Contribution to journalArticle

3 Scopus citations

Predictors of obtaining polysomnography among otolaryngologists prior to adenotonsillectomy for childhood sleep-disordered breathing

Lam, D. J., Shea, S. A., Weaver, E. M. & Mitchell, R. B., Aug 15 2018, In : Journal of Clinical Sleep Medicine. 14, 8, p. 1361-1367 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Resident physician extended work hours and burnout

McHill, A. W., Czeisler, C. A. & Shea, S., Aug 1 2018, In : Sleep. 41, 8

Research output: Contribution to journalEditorial

Role of the circadian system in cardiovascular disease

Thosar, S. S., Butler, M. & Shea, S., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2157-2167 11 p.

Research output: Contribution to journalReview article

38 Scopus citations

Sleep & work, work & sleep

Buxton, O. M. & Shea, S., Dec 1 2018, In : Sleep Health. 4, 6, p. 497-498 2 p.

Research output: Contribution to journalEditorial

2 Scopus citations

Sleep disturbance after pediatric traumatic brain injury: Critical knowledge gaps remain for the critically injured

Williams, C. N., Lim, M. & Shea, S., Jan 1 2018, In : Nature and Science of Sleep. 10, p. 225-228 4 p.

Research output: Contribution to journalEditorial

4 Scopus citations

The importance of the circadian system & sleep for bone health

Swanson, C. M., Kohrt, W. M., Buxton, O. M., Everson, C. A., Wright, K. P., Orwoll, E. S. & Shea, S. A., Jul 2018, In : Metabolism: Clinical and Experimental. 84, p. 28-43 16 p.

Research output: Contribution to journalArticle

12 Scopus citations
2017

24-hour profile of serum sclerostin and its association with bone biomarkers in men

Swanson, C., Shea, S. A., Wolfe, P., Markwardt, S., Cain, S. W., Munch, M., Czeisler, C. A., Orwoll, E. S. & Buxton, O. M., Nov 1 2017, In : Osteoporosis International. 28, 11, p. 3205-3213 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Bone turnover markers after sleep restriction and circadian disruption: A mechanism for sleep-related bone loss in humans

Swanson, C. M., Shea, S. A., Wolfe, P., Cain, S. W., Munch, M., Vujović, N., Czeisler, C. A., Buxton, O. M. & Orwoll, E. S., Oct 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 10, p. 3722-3730 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Recent legalization of cannabis use: Effects on sleep, health, and workplace safety

Bowles, N. P., Herzig, M. X. & Shea, S., Jan 1 2017, In : Nature and Science of Sleep. 9, p. 249-251 3 p.

Research output: Contribution to journalEditorial

2 Scopus citations
2016

A growth spurt in pediatric sleep research

Lam, D. & Shea, S., 2016, In : Nature and Science of Sleep. 8, p. 133-135 3 p.

Research output: Contribution to journalReview article

1 Scopus citations

Are we underestimating the lifelong benefits of therapy for obstructive sleep apnea?

Berman, A. M., Thosar, S. S. & Shea, S., 2016, In : Nature and Science of Sleep. 8, p. 87-89 3 p.

Research output: Contribution to journalEditorial

Assessment of pediatric obstructive sleep apnea using a drug-induced sleep endoscopy rating scale

Lam, D., Weaver, E. M., Macarthur, C., Milczuk, H., O'Neill, E., Smith, T., Nguyen, T. & Shea, S., 2016, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

16 Scopus citations

ATS core curriculum 2016: Part I. adult sleep medicine

Balachandran, J. S., Thomson, C. C., Sumter, D. B., Shelgikar, A. V., Lachapelle, P., Pamidi, S., Fall, M., Lal, C., Baba, R. Y., Shah, N., Fields, B. G., Sarmiento, K., Butler, M., Shea, S., Baptiste, J. V., Sharkey, K. M. & Wang, T., Apr 1 2016, In : Annals of the American Thoracic Society. 13, 4, p. 549-561 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Circadian gene variants influence sleep and the sleep electroencephalogram in humans

Chang, A. M., Bjonnes, A. C., Aeschbach, D., Buxton, O. M., Gooley, J. J., Anderson, C., Van Reen, E., Cain, S. W., Czeisler, C. A., Duffy, J. F., Lockley, S. W., Shea, S. A., Scheer, F. A. J. L. & Saxena, R., May 27 2016, In : Chronobiology International. 33, 5, p. 561-573 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Impact of common diabetes risk variant in MTNR1B on sleep, circadian, and melatonin physiology

Lane, J. M., Chang, A. M., Bjonnes, A. C., Aeschbach, D., Anderson, C., Cade, B. E., Cain, S. W., Czeisler, C. A., Gharib, S. A., Gooley, J. J., Gottlieb, D. J., Grant, S. F. A., Klerman, E. B., Lauderdale, D. S., Lockley, S. W., Munch, M., Patel, S., Punjabi, N. M., Rajaratnam, S. M. W., Rueger, M. & 11 others, St. Hilaire, M. A., Santhi, N., Scheuermaier, K., Van Reen, E., Zee, P. C., Shea, S. A., Duffy, J. F., Buxton, O. M., Redline, S., Scheer, F. A. J. L. & Saxena, R., Jun 1 2016, In : Diabetes. 65, 6, p. 1741-1751 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results from a 3.5-Year, Longitudinal Randomized Controlled Trial

Hu, K., Riemersma-Van Der Lek, R. F., Patxot, M., Li, P., Shea, S. A., Scheer, F. A. J. L. & Van Someren, E. J. W., Jun 13 2016, In : Scientific Reports. 6, 27742.

Research output: Contribution to journalArticle

15 Scopus citations
2015

Brachial artery endothelial function is stable across the morning in young men

Thosar, S. S., Wiggins, C. C., Shea, S. A. & Wallace, J. P., Dec 1 2015, In : Cardiovascular Ultrasound. 13, 1, 36.

Research output: Contribution to journalArticle

1 Scopus citations

Endogenous circadian regulation of pro-inflammatory cytokines and chemokines in the presence of bacterial lipopolysaccharide in humans

Rahman, S. A., Castanon-Cervantes, O., Scheer, F. A. J. L., Shea, S. A., Czeisler, C. A., Davidson, A. J. & Lockley, S. W., Jul 1 2015, In : Brain, Behavior, and Immunity. 47, p. 4-13 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

Morris, C. J., Yang, J. N., Garcia, J. I., Myers, S., Bozzi, I., Wang, W., Buxton, O. M., Shea, S. A. & Scheer, F. A. J. L., Apr 28 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 17, p. E2225-E2234

Research output: Contribution to journalArticle

139 Scopus citations

Obstructive sleep apnea and metabolic bone disease: Insights into the relationship between bone and sleep

Swanson, C. M., Shea, S. A., Stone, K. L., Cauley, J. A., Rosen, C. J., Redline, S., Karsenty, G. & Orwoll, E. S., Feb 1 2015, In : Journal of Bone and Mineral Research. 30, 2, p. 199-211 13 p.

Research output: Contribution to journalReview article

41 Scopus citations

The circadian system contributes to apnea lengthening across the night in obstructive sleep apnea

Butler, M. P., Smales, C., Wu, H., Hussain, M. V., Mohamed, Y. A., Morimoto, M. & Shea, S. A., Nov 1 2015, In : Sleep. 38, 11, p. 1793-1801 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2014

Human circadian system causes a morning peak in prothrombotic plasminogen activator inhibitor-1 (PAI-1) independent of the sleep/wake cycle

Scheer, F. A. J. L. & Shea, S. A., Jan 23 2014, In : Blood. 123, 4, p. 590-593 4 p.

Research output: Contribution to journalArticle

67 Scopus citations

Simulated shift work in rats perturbs multiscale regulation of locomotor activity

Hsieh, W. H., Escobar, C., Yugay, T., Lo, M. T., Pittman-Polletta, B., Salgado-Delgado, R., Scheer, F. A. J. L., Shea, S. A., Buijs, R. M. & Hu, K., Jul 6 2014, In : Journal of the Royal Society Interface. 11, 96, 20140318.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Evaluation of a single-channel nasal pressure device to assess obstructive sleep apnea risk in laboratory and home environments

Crowley, K. E., Rajaratnam, S. M. W., Shea, S. A., Epstein, L. J., Czeisler, C. A. & Lockley, S. W., Feb 25 2013, In : Journal of Clinical Sleep Medicine. 9, 2, p. 109-116 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia

Hu, K., Harper, D. G., Shea, S. A., Stopa, E. G. & Scheer, F. A. J. L., Jul 18 2013, In : Scientific Reports. 3, 2229.

Research output: Contribution to journalArticle

30 Scopus citations

The internal circadian clock increases hunger and appetite in the evening independent of food intake and other behaviors

Scheer, F. A. J. L., Morris, C. J. & Shea, S. A., Mar 1 2013, In : Obesity. 21, 3, p. 421-423 3 p.

Research output: Contribution to journalArticle

85 Scopus citations

The role of the circadian system in fractal neurophysiological control

Pittman-Polletta, B. R., Scheer, F. A. J. L., Butler, M. P., Shea, S. A. & Hu, K., Nov 1 2013, In : Biological Reviews. 88, 4, p. 873-894 22 p.

Research output: Contribution to journalArticle

32 Scopus citations
2012

Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

Buxton, O. M., Cain, S. W., O'Connor, S. P., Porter, J. H., Duffy, J. F., Wang, W., Czeisler, C. A. & Shea, S. A., Apr 11 2012, In : Science translational medicine. 4, 129, 129ra43.

Research output: Contribution to journalArticle

386 Scopus citations

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

Jeyaraj, D., Haldar, S. M., Wan, X., McCauley, M. D., Ripperger, J. A., Hu, K., Lu, Y., Eapen, B. L., Sharma, N., Ficker, E., Cutler, M. J., Gulick, J., Sanbe, A., Robbins, J., Demolombe, S., Kondratov, R. V., Shea, S. A., Albrecht, U., Wehrens, X. H. T., Rosenbaum, D. S. & 1 others, Jain, M. K., Mar 1 2012, In : Nature. 483, 7387, p. 96-101 6 p.

Research output: Contribution to journalArticle

190 Scopus citations

Fractal Patterns of Neural Activity Exist within the Suprachiasmatic Nucleus and Require Extrinsic Network Interactions

Hu, K., Meijer, J. H., Shea, S. A., vanderLeest, H. T., Pittman-Polletta, B., Houben, T., van Oosterhout, F., Deboer, T. & Scheer, F. A. J. L., Nov 27 2012, In : PloS one. 7, 11, e48927.

Research output: Contribution to journalArticle

27 Scopus citations

Klf15 orchestrates circadian nitrogen homeostasis

Jeyaraj, D., Scheer, F. A. J. L., Ripperger, J. A., Haldar, S. M., Lu, Y., Prosdocimo, D. A., Eapen, S. J., Eapen, B. L., Cui, Y., Mahabeleshwar, G. H., Lee, H. G., Smith, M. A., Casadesus, G., Mintz, E. M., Sun, H., Wang, Y., Ramsey, K. M., Bass, J., Shea, S. A., Albrecht, U. & 1 others, Jain, M. K., Mar 7 2012, In : Cell Metabolism. 15, 3, p. 311-323 13 p.

Research output: Contribution to journalArticle

66 Scopus citations

Obesity and pharmacologic control of the body clock

Shea, S. A., Jul 12 2012, In : New England Journal of Medicine. 367, 2, p. 175-178 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Repeated melatonin supplementation improves sleep in hypertensive patients treated with beta-blockers: A randomized controlled trial

Scheer, F. A. J. L., Morris, C. J., Garcia, J. I., Smales, C., Kelly, E. E., Marks, J., Malhotra, A. & Shea, S. A., Oct 1 2012, In : Sleep. 35, 10, p. 1395-1402 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
2011

Endogenous circadian rhythm in vasovagal response to head-up tilt

Hu, K., Scheer, F. A. J. L., Laker, M., Smales, C. & Shea, S. A., Mar 8 2011, In : Circulation. 123, 9, p. 961-970 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Existence of an endogenous circadian blood pressure rhythm in humans that peaks in the evening

Shea, S. A., Hilton, M. F., Hu, K. & Scheer, F. A. J. L., Apr 15 2011, In : Circulation research. 108, 8, p. 980-984 5 p.

Research output: Contribution to journalArticle

79 Scopus citations

Health disparities in sleep medicine: Responses to the American Sleep Medicine Foundation humanitarian projects award program

Wise, M. S., Morgenthaler, T., Badr, S., Gruber, R., Redline, S. & Shea, S. A., Dec 1 2011, In : Journal of Clinical Sleep Medicine. 7, 6, p. 583-584 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Response to letter regarding article, endogenous circadian rhythm in vasovagal response to head-up tilt

Hu, K., Scheer, F. A. J. L., Shea, S. A., Laker, M. & Smales, C., Sep 27 2011, In : Circulation. 124, 13, p. e359

Research output: Contribution to journalLetter