Projects per year
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- 8 Similar Profiles
Sulfonylurea Receptors
Medicine & Life Sciences
Adenosine Triphosphate
Medicine & Life Sciences
KATP Channels
Medicine & Life Sciences
Congenital Hyperinsulinism
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Insulin
Medicine & Life Sciences
Diazoxide
Medicine & Life Sciences
Potassium Channels
Medicine & Life Sciences
Network
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Projects 2000 2020
- 2 Active
Structural Basis of Katp Channel Gating
1/1/04 → 11/30/19
Project: Research project › Research Project
KATP Channels
Congenital Hyperinsulinism
Mutation
ATP-Binding Cassette Transporters
Sulfonylurea Receptors
ATP-SENSITIVE POTASSIUM CHANNELS AND INSULIN SECRETION
4/1/00 → 7/31/20
Project: Research project › Research Project
KATP Channels
Insulin
Phosphatidylinositols
Congenital Hyperinsulinism
Mutation
Research Output 1989 2018
1
Citations
Methods for characterizing disease-associated ATP-sensitive potassium channel mutations
Kandasamy, B. & Shyng, S. L., 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1684, p. 85-104 20 p. (Methods in Molecular Biology; vol. 1684)Research output: Chapter in Book/Report/Conference proceeding › Chapter
KATP Channels
Sulfonylurea Receptors
Mutation
Congenital Hyperinsulinism
Adenosine Triphosphate
Probing Subunits Interactions in KATP Channels Using Photo-Crosslinking via Genetically Encoded p-Azido-l-phenylalanine
Devaraneni, P., Rex, E. A. & Shyng, S. L., 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1684, p. 51-61 11 p. (Methods in Molecular Biology; vol. 1684)Research output: Chapter in Book/Report/Conference proceeding › Chapter
Phenylalanine
Adenosine Triphosphate
Ligands
Potassium Channels
Sulfonylurea Receptors
12
Citations
Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM
Martin, G. M., Kandasamy, B., Dimaio, F., Yoshioka, C. & Shyng, S. L., Oct 16 2017, In : eLife. 6, e31054Research output: Contribution to journal › Article
Glyburide
Adenosine Triphosphate
Binding Sites
Pharmaceutical Preparations
Lipid bilayers
38
Citations
Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating
Martin, G. M., Yoshioka, C., Rex, E. A., Fay, J. F., Xie, Q., Whorton, M. R., Chen, J. Z. & Shyng, S. L., Jan 16 2017, In : eLife. 6, e24149Research output: Contribution to journal › Article
KATP Channels
Glyburide
Adenosine Triphosphate
Hypoglycemic Agents
Conformations
NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic Β-cells
Wu, Y., Fortin, D. A., Cochrane, V. A., Chen, P. C. & Shyng, S. L., 2017, In : Journal of Biological Chemistry. 292, 37, p. 15512-15524 13 p.Research output: Contribution to journal › Article
Potassium Channels
Leptin
N-Methyl-D-Aspartate Receptors
AMP-Activated Protein Kinases
Adenosine Triphosphate