• 3822 Citations
  • 34 h-Index
1974 …2021
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Nucleoside Transport Proteins Medicine & Life Sciences
Parasites Medicine & Life Sciences
Leishmania Medicine & Life Sciences
Leishmania enriettii Medicine & Life Sciences
Facilitative Glucose Transport Proteins Medicine & Life Sciences
Leishmania donovani Medicine & Life Sciences
Membrane Transport Proteins Medicine & Life Sciences
Leishmania mexicana Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1988 2021

Trypanosomiasis
Trypanosoma brucei brucei
Parasites
Flagella
Proteins

The Role of the Kharon Complex in Leishmania Virulence

Landfear, S.

National Institutes of Health

7/1/156/30/17

Project: Research projectExploratory/Developmental Grants

Leishmania
Flagella
Virulence
Macrophages
Parasites

Development of Drugs that Target the Malaria Hexose Transporter

Landfear, S.

National Institutes of Health

7/1/156/30/17

Project: Research projectExploratory/Developmental Grants

Monosaccharide Transport Proteins
Malaria
Parasites
Glucose
Pharmaceutical Preparations

Selective Inhibitors of the Hexose Transporter from African Trypansomes

Landfear, S.

National Institutes of Health

2/1/131/31/16

Project: Research projectExploratory/Developmental Grants

Monosaccharide Transport Proteins
Leishmania mexicana
African Trypanosomiasis
Parasites
Trypanosoma brucei brucei

Research Output 1974 2018

  • 3822 Citations
  • 34 h-Index
  • 95 Article
  • 2 Chapter
2 Citations

Leishmania mexicana can utilize amino acids as major carbon sources in macrophages but not in animal models

Saunders, E. C., Naderer, T., Chambers, J., Landfear, S. M. & Mcconville, M. J., Jan 1 2018, (Accepted/In press) In : Molecular Microbiology.

Research output: Contribution to journalArticle

Leishmania mexicana
Carbon
Animal Models
Macrophages
Amino Acids
1 Citations

Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

Ortiz, D., Guiguemde, W. A., Hammill, J. T., Carrillo, A. K., Chen, Y., Connelly, M., Stalheim, K., Elya, C., Johnson, A., Min, J., Shelat, A., Smithson, D. C., Yang, L., Zhu, F., Guy, R. K. & Landfear, S. M., Dec 1 2017, In : PLoS Neglected Tropical Diseases. 11, 12, p. e0006157

Research output: Contribution to journalArticle

Parasitic Diseases
Leishmaniasis
miltefosine
Parasites
Pharmacokinetics
1 Citations

KHARON is an essential cytoskeletal protein involved in the trafficking of flagellar membrane proteins and cell division in african trypanosomes

Sanchez, M. A., Tran, K. D., Valli, J., Hobbs, S., Johnson, E., Gluenz, E. & Landfear, S. M., Sep 16 2016, In : Journal of Biological Chemistry. 291, 38, p. 19760-19773 14 p.

Research output: Contribution to journalArticle

Cytoskeletal Proteins
Trypanosomiasis
Cell Division
Membrane Proteins
Parasites
62 Citations

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Van Voorhis, W. C., Adams, J. H., Adelfio, R., Ahyong, V., Akabas, M. H., Alano, P., Alday, A., Alemán Resto, Y., Alsibaee, A., Alzualde, A., Andrews, K. T., Avery, S. V., Avery, V. M., Ayong, L., Baker, M., Baker, S., Ben Mamoun, C., Bhatia, S., Bickle, Q., Bounaadja, L. & 167 othersBowling, T., Bosch, J., Boucher, L. E., Boyom, F. F., Brea, J., Brennan, M., Burton, A., Caffrey, C. R., Camarda, G., Carrasquilla, M., Carter, D., Belen Cassera, M., Chih-Chien Cheng, K., Chindaudomsate, W., Chubb, A., Colon, B. L., Colón-López, D. D., Corbett, Y., Crowther, G. J., Cowan, N., D’Alessandro, S., Le Dang, N., Delves, M., DeRisi, J. L., Du, A. Y., Duffy, S., Abd El-Salam El-Sayed, S., Ferdig, M. T., Fernández Robledo, J. A., Fidock, D. A., Florent, I., Fokou, P. V. T., Galstian, A., Gamo, F. J., Gokool, S., Gold, B., Golub, T., Goldgof, G. M., Guha, R., Guiguemde, W. A., Gural, N., Guy, R. K., Hansen, M. A. E., Hanson, K. K., Hemphill, A., Hooft van Huijsduijnen, R., Horii, T., Horrocks, P., Hughes, T. B., Huston, C., Igarashi, I., Ingram-Sieber, K., Itoe, M. A., Jadhav, A., Naranuntarat Jensen, A., Jensen, L. T., Jiang, R. H. Y., Kaiser, A., Keiser, J., Ketas, T., Kicka, S., Kim, S., Kirk, K., Kumar, V. P., Kyle, D. E., Lafuente, M. J., Landfear, S., Lee, N., Lee, S., Lehane, A. M., Li, F., Little, D., Liu, L., Llinás, M., Loza, M. I., Lubar, A., Lucantoni, L., Lucet, I., Maes, L., Mancama, D., Mansour, N. R., March, S., McGowan, S., Medina Vera, I., Meister, S., Mercer, L., Mestres, J., Mfopa, A. N., Misra, R. N., Moon, S., Moore, J. P., Morais Rodrigues da Costa, F., Müller, J., Muriana, A., Nakazawa Hewitt, S., Nare, B., Nathan, C., Narraidoo, N., Nawaratna, S., Ojo, K. K., Ortiz, D., Panic, G., Papadatos, G., Parapini, S., Patra, K., Pham, N., Prats, S., Plouffe, D. M., Poulsen, S. A., Pradhan, A., Quevedo, C., Quinn, R. J., Rice, C. A., Abdo Rizk, M., Ruecker, A., St. Onge, R., Salgado Ferreira, R., Samra, J., Robinett, N. G., Schlecht, U., Schmitt, M., Silva Villela, F., Silvestrini, F., Sinden, R., Smith, D. A., Soldati, T., Spitzmüller, A., Stamm, S. M., Sullivan, D. J., Sullivan, W., Suresh, S., Suzuki, B. M., Suzuki, Y., Swamidass, S. J., Taramelli, D., Tchokouaha, L. R. Y., Theron, A., Thomas, D., Tonissen, K. F., Townson, S., Tripathi, A. K., Trofimov, V., Udenze, K. O., Ullah, I., Vallieres, C., Vigil, E., Vinetz, J. M., Voong Vinh, P., Vu, H., Watanabe, N. A., Weatherby, K., White, P. M., Wilks, A. F., Winzeler, E. A., Wojcik, E., Wree, M., Wu, W., Yokoyama, N., Zollo, P. H. A., Abla, N., Blasco, B., Burrows, J., Laleu, B., Leroy, D., Spangenberg, T., Wells, T. & Willis, P. A., Jul 1 2016, In : PLoS Pathogens. 12, 7, e1005763.

Research output: Contribution to journalArticle

Neglected Diseases
Drug Discovery
Malaria
Pharmaceutical Chemistry
Information Dissemination
8 Citations

Targeting the cytochrome bc1 complex of Leishmania parasites for discovery of novel drugs

Ortiz, D., Forquer, I., Boitz, J., Soysa, R., Elya, C., Fulwiler, A., Nilsen, A., Polley, T., Riscoe, M. K., Ullman, B. & Landfear, S. M., Aug 1 2016, In : Antimicrobial Agents and Chemotherapy. 60, 8, p. 4972-4982 11 p.

Research output: Contribution to journalArticle

Electron Transport Complex III
Leishmania
Quinolones
Drug Discovery
Parasites