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Philip Stork

Professor

  • 8786 Citations
  • 45 h-Index
1976 …2018
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  • 3 Similar Profiles
Extracellular Signal-Regulated MAP Kinases Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences
Chemical activation Chemical Compounds
Monomeric GTP-Binding Proteins Medicine & Life Sciences
Cyclic AMP Medicine & Life Sciences
PC12 Cells Medicine & Life Sciences
Nerve Growth Factor Medicine & Life Sciences
Cyclic AMP-Dependent Protein Kinases Medicine & Life Sciences

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Projects 1990 2018

Identifying new drug targets to block K-Ras/Raf in pancreatic cancer.

Stork, P.

National Institutes of Health

12/1/14 → 11/30/16

Project: Research project

Pancreatic Neoplasms
Phosphotransferases
Phosphorylation
Adenocarcinoma
Pharmaceutical Preparations

Spatial control of cAMP signaling by Epacs

Stork, P.

National Institutes of Health

8/15/11 → 6/30/16

Project: Research project

Monomeric GTP-Binding Proteins
Nuclear Pore
Catenins
Proteins
Cyclic AMP

The small G protein Rap 1 in Tau cell activation/anergy

Stork, P.

National Institutes of Health

3/15/01 → 2/28/06

Project: Research project

Monomeric GTP-Binding Proteins
Interleukin-2
T-Lymphocytes
Phosphotransferases
T-Cell Antigen Receptor

NEURONAL ACTIVITY AND INTRACELLULAR SIGNALING

Stork, P.

National Institutes of Health

9/1/00 → 8/31/05

Project: Research project

Calcium
Protein Kinases
Monomeric GTP-Binding Proteins
Extracellular Signal-Regulated MAP Kinases
Neuronal Plasticity

HORMONAL REGULATION OF MAP KINASE VIA RAP1 AND B-RAF

Stork, P.

National Institutes of Health

8/1/97 → 5/31/12

Project: Research project

Cyclic AMP
Phosphotransferases
Mitogen-Activated Protein Kinases
Hormones
GTP-Binding Proteins

Research Output 1976 2018

  • 8786 Citations
  • 45 h-Index
  • 89 Article

Proceedings of the fifth international RASopathies symposium: When development and cancer intersect

Rauen, K. A., Schoyer, L., Schill, L., Stronach, B., Albeck, J., Andresen, B. S., Cavé, H., Ellis, M., Fruchtman, S. M., Gelb, B. D., Gibson, C. C., Gripp, K., Hefner, E., Huang, W. Y. C., Itkin, M., Kerr, B., Linardic, C. M., McMahon, M., Oberlander, B., Perlstein, E. & 17 others, Ratner, N., Rogers, L., Schenck, A., Shankar, S., Shvartsman, S., Stevenson, D. A., Stites, E. C., Stork, P., Sun, C., Therrien, M., Ullian, E. M., Widemann, B. C., Yeh, E., Zampino, G., Zenker, M., Timmer, W. & McCormick, F., Jan 1 2018, (Accepted/In press) In : American Journal of Medical Genetics, Part A. e40632.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinases
Neoplasms
Musculoskeletal Abnormalities
Skin Abnormalities
Eye Abnormalities
1 Citation (Scopus)

Analysis of K-Ras interactions by biotin ligase tagging

Ritchie, C., Mack, A., Harper, L., Alfadhli, A., Stork, P., Nan, X. & Barklis, E., Jul 1 2017, In : Cancer Genomics and Proteomics. 14, 4, p. 225-239 15 p.

Research output: Contribution to journal › Article

Ligases
Biotin
ras Proteins
Cells
Prenylation
9 Citations (Scopus)

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates

Tillo, S. E., Xiong, W-H., Takahashi, M., Miao, S., Andrade, A. L., Fortin, D. A., Yang, G., Qin, M., Smoody, B. F., Stork, P. & Zhong, H., Apr 18 2017, In : Cell Reports. 19, 3, p. 617-629 13 p.

Research output: Contribution to journal › Article

Cyclic AMP-Dependent Protein Kinases
Catalytic Domain
Membranes
Substrates
Protein Kinase C
10 Citations (Scopus)

Phosphorylation of Rap1 by cAMP-dependent protein kinase (PKA) creates a binding site for KSR to sustain ERK activation by cAMP

Takahashi, M., Li, Y., Dillon, T. J. & Stork, P., Jan 27 2017, In : Journal of Biological Chemistry. 292, 4, p. 1449-1461 13 p.

Research output: Contribution to journal › Article

Phosphorylation
Extracellular Signal-Regulated MAP Kinases
Cyclic AMP-Dependent Protein Kinases
Cyclic AMP
Chemical activation
3 Citations (Scopus)

Phosphorylation of the C-Raf N region promotes Raf dimerization

Takahashi, M., Li, Y., Dillon, T. J., Kariya, Y. & Stork, P., Oct 1 2017, In : Molecular and Cellular Biology. 37, 19, e00132-17.

Research output: Contribution to journal › Article

Dimerization
Phosphorylation
Extracellular Signal-Regulated MAP Kinases
Serine
Tyrosine