Michael Riscoe

Gimenez, V. M. M., Alvarenga, T. A., Groppo, M., Silva, M. L. A. E., Cunha, W. R., Januário, A. H., Smilkstein, M. J., Riscoe, M. & Pauletti, P. M., Jan 1 2018, (Accepted/In press) In : Brazilian Journal of Pharmacognosy.

Research output: Contribution to journal › Article

Anacardium

Phenols

Inhibitory Concentration 50

Anacardic Acids

Ethanol

Endochin-like quinolones exhibit promising efficacy against neospora caninum in vitro and in experimentally infected pregnant mice

Anghel, N., Balmer, V., Müller, J., Winzer, P., Aguado-Martinez, A., Roozbehani, M., Pou, S., Nilsen, A., Riscoe, M., Doggett, J. & Hemphill, A., Nov 19 2018, In : Frontiers in Veterinary Science. 5, NOV, 285.

Research output: Contribution to journal › Article

Neospora

quinolones

Neospora caninum

Quinolones

mice

1 Citations

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc₁ and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

McConnell, E. V., Bruzual, I., Pou, S., Winter, R., Dodean, R. A., Smilkstein, M. J., Krollenbrock, A., Nilsen, A., Zakharov, L. N., Riscoe, M. & Doggett, J., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journal › Article

4-Quinolones

Electron Transport Complex III

Toxoplasmosis

Quinolones

4 Citations

Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria

Frueh, L., Li, Y., Mather, M. W., Li, Q., Pou, S., Nilsen, A., Winter, R. W., Forquer, I. P., Pershing, A. M., Xie, L. H., Smilkstein, M. J., Caridha, D., Koop, D., Campbell, R. F., Sciotti, R. J., Kreishman-Deitrick, M., Kelly, J. X., Vesely, B., Vaidya, A. B. & Riscoe, M., Oct 13 2017, In : ACS Infectious Diseases. 3, 10, p. 728-735 8 p.

Research output: Contribution to journal › Article

Prodrugs

Malaria

Esters

Pharmaceutical Preparations

Plasmodium yoelii

15 Citations

Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes

Boitz, J. M., Gilroy, C. A., Olenyik, T. D., Paradis, D., Perdeh, J., Dearman, K., Davis, M. J., Yates, P., Li, Y., Riscoe, M., Ullman, B. & Roberts, S. C., 2017, In : Infection and Immunity. 85, 1, e00554-16.

Research output: Contribution to journal › Article

Leishmania donovani

Arginase

Polyamines

Ornithine

Parasites