• 3150 Citations
  • 28 h-Index
1983 …2021
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Fingerprint Dive into the research topics where Michael Riscoe is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Antimalarials Medicine & Life Sciences
adenosylhomocysteine nucleosidase Medicine & Life Sciences
Quinolones Medicine & Life Sciences
Parasites Medicine & Life Sciences
Plasmodium falciparum Medicine & Life Sciences
Malaria Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Electron Transport Complex III Medicine & Life Sciences

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Projects 2003 2021

Antimalarials
Malaria
Multiple Drug Resistance
Chloroquine
Amodiaquine
Equipment and Supplies
Research
Health Services Research
Delivery of Health Care
Arthritis
Quinolones
Malaria
Sporozoites
Parasites
Antimalarials
Malaria
Pharmaceutical Preparations
Parasites
Chloroquine
Therapeutics
Chloroquine
Malaria
Pharmaceutical Preparations
Mefloquine
Quinine

Research Output 1983 2019

  • 3150 Citations
  • 28 h-Index
  • 76 Article

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials

Dodean, R. A., Kancharla, P., Li, Y., Melendez, V., Read, L., Bane, C. E., Vesely, B., Kreishman-Deitrick, M., Black, C., Li, Q., Sciotti, R. J., Olmeda, R., Luong, T. L., Gaona, H., Potter, B., Sousa, J., Marcsisin, S., Caridha, D., Xie, L., Vuong, C. & 19 othersZeng, Q., Zhang, J., Zhang, P., Lin, H., Butler, K., Roncal, N., Gaynor-Ohnstad, L., Leed, S. E., Nolan, C., Huezo, S. J., Rasmussen, S. A., Stephens, M. T., Tan, J. C., Cooper, R. A., Smilkstein, M. J., Pou, S., Winter, R. W., Riscoe, M. & Kelly, J. X., Apr 11 2019, In : Journal of Medicinal Chemistry. 62, 7, p. 3475-3502 28 p.

Research output: Contribution to journalArticle

Acridones
Antimalarials
Malaria
Plasmodium berghei
Sporozoites

Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

Ke, H., Ganesan, S. M., Dass, S., Morrisey, J. M., Pou, S., Nilsen, A., Riscoe, M., Mather, M. W. & Vaidya, A. B., Apr 1 2019, In : PloS one. 14, 4, e0214023.

Research output: Contribution to journalArticle

Open Access
NADH dehydrogenase
Plasmodium falciparum
Parasites
antimalarials
Blood

Antiplasmodial evaluation of Anacardium occidentale and alkyl-phenols

Gimenez, V. M. M., Alvarenga, T. A., Groppo, M., Silva, M. L. A. E., Cunha, W. R., Januário, A. H., Smilkstein, M. J., Riscoe, M. & Pauletti, P. M., Jan 1 2018, (Accepted/In press) In : Brazilian Journal of Pharmacognosy.

Research output: Contribution to journalArticle

Anacardium
Phenols
Inhibitory Concentration 50
Anacardic Acids
Ethanol

Endochin-like quinolones exhibit promising efficacy against neospora caninum in vitro and in experimentally infected pregnant mice

Anghel, N., Balmer, V., Müller, J., Winzer, P., Aguado-Martinez, A., Roozbehani, M., Pou, S., Nilsen, A., Riscoe, M., Doggett, J. & Hemphill, A., Nov 19 2018, In : Frontiers in Veterinary Science. 5, NOV, 285.

Research output: Contribution to journalArticle

Neospora
quinolones
Neospora caninum
Quinolones
mice
2 Citations (Scopus)

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

McConnell, E. V., Bruzual, I., Pou, S., Winter, R., Dodean, R. A., Smilkstein, M. J., Krollenbrock, A., Nilsen, A., Zakharov, L. N., Riscoe, M. & Doggett, J., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Qi
4-Quinolones
Electron Transport Complex III
Toxoplasmosis
Quinolones