Projects per year
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- 2 Similar Profiles
Antimalarials
Medicine & Life Sciences
adenosylhomocysteine nucleosidase
Medicine & Life Sciences
Quinolones
Medicine & Life Sciences
Parasites
Medicine & Life Sciences
Plasmodium falciparum
Medicine & Life Sciences
Pharmaceutical Preparations
Medicine & Life Sciences
Malaria
Medicine & Life Sciences
Chloroquine
Medicine & Life Sciences
Network
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Projects 2003 2021
Design and Optimization of Novel Antimalarial Drugs
4/1/16 → 3/31/21
Project: Research project › Non-HHS Research Projects
Antimalarials
Malaria
Multiple Drug Resistance
Chloroquine
Amodiaquine
ShEEP Request for Parkin-Elmer Spectrum Series Bio-imaging Device
5/1/16 → 9/30/16
Project: Research project
Equipment and Supplies
Research
Health Services Research
Delivery of Health Care
Arthritis
Optimizing ELQs for Treatment and Prevention of Malaria
7/1/12 → 11/30/17
Project: Research project › High Priority, Short Term Project Award, Research Project
Quinolones
Malaria
Sporozoites
Parasites
Antimalarials
Optimizing Pharmachins for Treatment and Prevention of Drug Resistant Malaria
1/1/12 → 12/31/15
Project: Research project › Non-HHS Research Projects
Malaria
Pharmaceutical Preparations
Parasites
Chloroquine
Therapeutics
Development of a Chloroquine Replacement Drug
9/25/09 → 8/31/12
Project: Research project › NIH Challenge Grants and Partnerships Program
Chloroquine
Malaria
Pharmaceutical Preparations
Mefloquine
Quinine
Research Output 1983 2017
- 2851 Citations
- 28 h-Index
- 71 Article
1
Citations
Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria
Frueh, L., Li, Y., Mather, M. W., Li, Q., Pou, S., Nilsen, A., Winter, R. W., Forquer, I. P., Pershing, A. M., Xie, L. H., Smilkstein, M. J., Caridha, D., Koop, D. R., Campbell, R. F., Sciotti, R. J., Kreishman-Deitrick, M., Kelly, J. X., Vesely, B., Vaidya, A. B. & Riscoe, M. K. Oct 13 2017 In : ACS Infectious Diseases. 3, 10, p. 728-735 8 p.Research output: Contribution to journal › Article
Prodrugs
Malaria
Esters
Pharmaceutical Preparations
Plasmodium yoelii
13
Citations
Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes
Boitz, J. M., Gilroy, C. A., Olenyik, T. D., Paradis, D., Perdeh, J., Dearman, K., Davis, M. J., Yates, P. A., Li, Y., Riscoe, M. K., Ullman, B. & Roberts, S. C. 2017 In : Infection and Immunity. 85, 1, e00554-16Research output: Contribution to journal › Article
Leishmania donovani
Arginase
Polyamines
Ornithine
Parasites
4
Citations
Genetic evidence for cytochrome b Qi site inhibition by 4(1H)-quinolone-3-diarylethers and antimycin in Toxoplasma gondii
Alday, P. H., Bruzual, I., Nilsen, A., Pou, S., Winter, R., Mamoun, C. B., Riscoe, M. K. & Doggett, J. S. Feb 1 2017 In : Antimicrobial Agents and Chemotherapy. 61, 2, e01866Research output: Contribution to journal › Article
4-Quinolones
Cytochromes b
Quinolones
Toxoplasma
Toxoplasmosis
5
Citations
Atovaquone and ELQ-300 combination therapy as a novel dual-site cytochrome bc1 inhibition strategy for malaria
Stickles, A. M., Smilkstein, M. J., Morrisey, J. M., Li, Y., Forquer, I. P., Kelly, J. X., Pou, S., Winter, R. W., Nilsen, A., Vaidya, A. B. & Riscoe, M. K. Aug 1 2016 In : Antimicrobial Agents and Chemotherapy. 60, 8, p. 4853-4859 7 p.Research output: Contribution to journal › Article
Atovaquone
Quinolones
Cytochromes
Malaria
Antimalarials
9
Citations
Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis
Foss, M. H., Pou, S., Davidson, P. M., Dunaj, J. L., Winter, R. W., Pou, S., Licon, M. H., Doh, J. K., Li, Y., Kelly, J. X., Dodean, R. A., Koop, D. R., Riscoe, M. K. & Purdy, G. E. Jul 8 2016 In : ACS Infectious Diseases. 2, 7, p. 500-508 9 p.Research output: Contribution to journal › Article
Diamines
Mycobacterium tuberculosis
Pharmaceutical Preparations
Infection
Extensively Drug-Resistant Tuberculosis