Michael Axthelm

Associate Scientist

  • 6353 Citations
  • 39 h-Index
1978 …2020
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Projects 1978 2020

Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research

Axthelm, M.

National Institutes of Health

8/1/167/31/20

Project: Research projectAnimal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements

Macaca mulatta
Macaca
breeding
Simian immunodeficiency virus
Human immunodeficiency virus

Consortium for AIDS Vaccine Research in Nonhuman Primates

Picker, L., Axthelm, M., Burton, D. R., Johnson, R. P., Shaw, G., Desrosiers, R., Haase, A. T., Sekaly, R. & Barouch, D. H.

National Institutes of Health

7/15/116/30/16

Project: Research projectResearch Program--Cooperative Agreements

Macaca mulatta
Infection
AIDS Vaccines
Primates
Vaccines

Development of an Effector-Memory T Cell AIDS Vaccine

Picker, L., Axthelm, M., Nelson, J., Kahl, C. A., Frueh, K., Sekaly, R., Barry, P. & Fruh, K.

National Institutes of Health

7/15/116/30/17

Project: Research projectResearch Program Projects

AIDS Vaccines
Macaca mulatta
Vaccines
Cytomegalovirus Vaccines
T-Lymphocytes

Pacific NorthWest Regional Center of Excellence (PNWRCE)

Streblow, D., Slifka, M., McWeeney, S., Axthelm, M., Moses, A., Nelson, J., Baric, R., Landfear, S., Nikolich-Zugich, J., Barklis, E., Gale, M., Katze, M., Kawaoka, Y., Bevan, M., Smith, R., Maizels, N., Frueh, K., Labeaud, A. D., Ryman, K., Chanda, S., Galloway, D. A. & Fruh, K.

National Institutes of Health

4/20/092/28/15

Project: Research projectSpecialized Center--Cooperative Agreements

Northwestern United States
National Institute of Allergy and Infectious Diseases (U.S.)
Vulnerable Populations
Research
Vaccines

Research Output 1981 2019

  • 6353 Citations
  • 39 h-Index
  • 126 Article

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

Hansen, S., Womack, J., Scholz, I., Renner, A., Edgel, K. A., Xu, G., Ford, J. C., Grey, M., St. Laurent, B., Turner, J. M., Planer, S., Legasse, A. W., Richie, T. L., Aguiar, J. C., Axthelm, M., Villasante, E. D., Weiss, W., Edlefsen, P. T., Picker, L. & Frueh, K., Jan 1 2019, In : PloS one. 14, 1, e0210252.

Research output: Contribution to journalArticle

Plasmodium knowlesi
Cytomegalovirus
Sporozoites
T-cells
Parasitemia
1 Citations

Combination adenovirus and protein vaccines prevent infection or reduce viral burden after heterologous clade C simian-human immunodeficiency virus mucosal challenge

Malherbe, D., Mendy, J., Vang, L., Barnette, P. T., Reed, J., Lakhashe, S. K., Owuor, J., Gach, J. S., Legasse, A. W., Axthelm, M., LaBranche, C. C., Montefiori, D., Forthal, D. N., Park, B., Wilson, J. M., McLinden, J. H., Xiang, J., Stapleton, J. T., Sacha, J., Haynes, B. F. & 6 othersLiao, H. X., Ruprecht, R. M., Smith, J., Gurwith, M., Haigwood, N. & Alexander, J., Jan 1 2018, In : Journal of Virology. 92, 2, e01092-17.

Research output: Contribution to journalArticle

Adenovirus Vaccines
Combined Vaccines
Simian Immunodeficiency Virus
Human immunodeficiency virus
Macaca

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

Okoye, A., Hansen, S., Vaidya, M., Fukazawa, Y., Park, H., Duell, D. M., Lum, R., Hughes, C. M., Ventura, A. B., Ainslie, E., Ford, J. C., Morrow, D., Gilbride, R. M., Legasse, A. W., Hesselgesser, J., Geleziunas, R., Li, Y., Oswald, K., Shoemaker, R., Fast, R. & 6 othersBosche, W. J., Borate, B. R., Edlefsen, P. T., Axthelm, M., Picker, L. & Lifson, J. D., Sep 1 2018, In : Nature medicine. 24, 9, p. 1430-1440 11 p.

Research output: Contribution to journalArticle

Simian Immunodeficiency Virus
Secondary Prevention
Viruses
Cytomegalovirus
Macaca mulatta
2 Citations

Potent immune modulation by medi6383, an engineered human ox40 ligand igg4p fc fusion protein

Oberst, M. D., Auge, C., Morris, C., Kentner, S., Mulgrew, K., McGlinchey, K., Hair, J., Hanabuchi, S., Du, Q., Damschroder, M., Feng, H., Eck, S., Buss, N., de Haan, L., Pierce, A. J., Park, H., Sylwester, A., Axthelm, M., Picker, L., Morris, N. P. & 2 othersWeinberg, A. & Hammond, S. A., May 1 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 1024-1038 15 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Proteins
Cell Proliferation
Neoplasms
Cytokines
18 Citations

Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine

Hansen, S., Zak, D. E., Xu, G., Ford, J. C., Marshall, E., Malouli, D., Gilbride, R. M., Hughes, C. M., Ventura, A. B., Ainslie, E., Randall, K. T., Selseth, A. N., Rundstrom, P., Herlache, L., Lewis, M. S., Park, H., Planer, S. L., Turner, J. M., Fischer, M., Armstrong, C. & 20 othersZweig, R. C., Valvo, J., Braun, J. M., Shankar, S., Lu, L., Sylwester, A., Legasse, A. W., Messerle, M., Jarvis, M. A., Amon, L. M., Aderem, A., Alter, G., Laddy, D. J., Stone, M., Bonavia, A., Evans, T. G., Axthelm, M., Frueh, K., Edlefsen, P. T. & Picker, L., Feb 1 2018, In : Nature Medicine. 24, 2, p. 130-143 14 p.

Research output: Contribution to journalArticle

Cytomegalovirus Vaccines
Macaca mulatta
Tuberculosis
Vaccines
Tuberculosis Vaccines