Michael Axthelm

Associate Scientist

Emailaxthelmm@ohsu.edu

6493 Citations
39 h-Index

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Projects 1978 2020

1 Active
11 Finished

Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research

Axthelm, M.

National Institutes of Health

8/1/16 → 7/31/20

Project: Research project

Macaca mulatta

Macaca

breeding

Simian immunodeficiency virus

Human immunodeficiency virus

Development of an Effector-Memory T Cell AIDS Vaccine

Picker, L., Axthelm, M., Nelson, J., Kahl, C. A., Frueh, K., Sekaly, R., Barry, P. & Fruh, K.

National Institutes of Health

7/15/11 → 6/30/17

Project: Research project

AIDS Vaccines

Macaca mulatta

Vaccines

Cytomegalovirus Vaccines

T-Lymphocytes

Consortium for AIDS Vaccine Research in Nonhuman Primates

Picker, L., Axthelm, M., Burton, D. R., Johnson, R. P., Shaw, G., Desrosiers, R., Haase, A. T., Sekaly, R. & Barouch, D. H.

National Institutes of Health

7/15/11 → 6/30/16

Project: Research project

Macaca mulatta

Infection

AIDS Vaccines

Primates

Vaccines

Pacific NorthWest Regional Center of Excellence (PNWRCE)

Streblow, D., Slifka, M., McWeeney, S., Axthelm, M., Moses, A., Nelson, J., Baric, R., Landfear, S., Nikolich-Zugich, J., Barklis, E., Gale, M., Katze, M., Kawaoka, Y., Bevan, M., Smith, R., Maizels, N., Frueh, K., Labeaud, A. D., Ryman, K., Chanda, S., Galloway, D. A. & Fruh, K.

National Institutes of Health

4/20/09 → 2/28/15

Project: Research project

Northwestern United States

National Institute of Allergy and Infectious Diseases (U.S.)

Vulnerable Populations

Research

Vaccines

23rd Annual Symposium on Nonhuman Primate Model for AIDS

Axthelm, M.

National Institutes of Health

7/1/05 → 6/30/06

Project: Research project

AIDS

poster

science

applicant

grant

Research Output 1981 2019

6493 Citations
39 h-Index
127 Article
2 Comment/debate

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

Hansen, S., Womack, J., Scholz, I., Renner, A., Edgel, K. A., Xu, G., Ford, J. C., Grey, M., St. Laurent, B., Turner, J. M., Planer, S., Legasse, A. W., Richie, T. L., Aguiar, J. C., Axthelm, M., Villasante, E. D., Weiss, W., Edlefsen, P. T., Picker, L. & Frueh, K., Jan 1 2019, In : PLoS One. 14, 1, e0210252.

Research output: Contribution to journal › Article

Plasmodium knowlesi

Cytomegalovirus

Sporozoites

T-cells

Parasitemia

Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome

GC6-74 Consortium, Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journal › Article

Open Access

Tuberculosis

Metabolomics

Transfer RNA Aminoacylation

Metabolome

Transcriptome

1 Citation (Scopus)

Combination adenovirus and protein vaccines prevent infection or reduce viral burden after heterologous clade C simian-human immunodeficiency virus mucosal challenge

Malherbe, D., Mendy, J., Vang, L., Barnette, P. T., Reed, J., Lakhashe, S. K., Owuor, J., Gach, J. S., Legasse, A. W., Axthelm, M., LaBranche, C. C., Montefiori, D., Forthal, D. N., Park, B., Wilson, J. M., McLinden, J. H., Xiang, J., Stapleton, J. T., Sacha, J., Haynes, B. F. & 6 othersLiao, H. X., Ruprecht, R. M., Smith, J., Gurwith, M., Haigwood, N. & Alexander, J., Jan 1 2018, In : Journal of Virology. 92, 2, e01092-17.

Research output: Contribution to journal › Article

Adenovirus Vaccines

Combined Vaccines

Simian Immunodeficiency Virus

Human immunodeficiency virus

Macaca

1 Citation (Scopus)

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

Okoye, A., Hansen, S., Vaidya, M., Fukazawa, Y., Park, H., Duell, D. M., Lum, R., Hughes, C. M., Ventura, A. B., Ainslie, E., Ford, J. C., Morrow, D., Gilbride, R. M., Legasse, A. W., Hesselgesser, J., Geleziunas, R., Li, Y., Oswald, K., Shoemaker, R., Fast, R. & 6 othersBosche, W. J., Borate, B. R., Edlefsen, P. T., Axthelm, M., Picker, L. & Lifson, J. D., Sep 1 2018, In : Nature Medicine. 24, 9, p. 1430-1440 11 p.

Research output: Contribution to journal › Article

Simian Immunodeficiency Virus

Secondary Prevention

Viruses

Cytomegalovirus

Macaca mulatta

2 Citations (Scopus)

Potent immune modulation by medi6383, an engineered human ox40 ligand igg4p fc fusion protein

Oberst, M. D., Auge, C., Morris, C., Kentner, S., Mulgrew, K., McGlinchey, K., Hair, J., Hanabuchi, S., Du, Q., Damschroder, M., Feng, H., Eck, S., Buss, N., de Haan, L., Pierce, A. J., Park, H., Sylwester, A., Axthelm, M., Picker, L., Morris, N. P. & 2 othersWeinberg, A. & Hammond, S. A., May 1 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 1024-1038 15 p.

Research output: Contribution to journal › Article

T-Lymphocytes

Proteins

Cell Proliferation

Neoplasms

Cytokines