Michael Axthelm

Associate Scientist

  • 6493 Citations
  • 39 h-Index
1978 …2020
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Projects 1978 2020

Macaca mulatta
Macaca
breeding
Simian immunodeficiency virus
Human immunodeficiency virus

Development of an Effector-Memory T Cell AIDS Vaccine

Picker, L., Axthelm, M., Nelson, J., Kahl, C. A., Frueh, K., Sekaly, R., Barry, P. & Fruh, K.

National Institutes of Health

7/15/116/30/17

Project: Research project

AIDS Vaccines
Macaca mulatta
Vaccines
Cytomegalovirus Vaccines
T-Lymphocytes

Consortium for AIDS Vaccine Research in Nonhuman Primates

Picker, L., Axthelm, M., Burton, D. R., Johnson, R. P., Shaw, G., Desrosiers, R., Haase, A. T., Sekaly, R. & Barouch, D. H.

National Institutes of Health

7/15/116/30/16

Project: Research project

Macaca mulatta
Infection
AIDS Vaccines
Primates
Vaccines

Pacific NorthWest Regional Center of Excellence (PNWRCE)

Streblow, D., Slifka, M., McWeeney, S., Axthelm, M., Moses, A., Nelson, J., Baric, R., Landfear, S., Nikolich-Zugich, J., Barklis, E., Gale, M., Katze, M., Kawaoka, Y., Bevan, M., Smith, R., Maizels, N., Frueh, K., Labeaud, A. D., Ryman, K., Chanda, S., Galloway, D. A. & Fruh, K.

National Institutes of Health

4/20/092/28/15

Project: Research project

Northwestern United States
National Institute of Allergy and Infectious Diseases (U.S.)
Vulnerable Populations
Research
Vaccines
AIDS
poster
science
applicant
grant

Research Output 1981 2019

  • 6493 Citations
  • 39 h-Index
  • 127 Article
  • 2 Comment/debate

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

Hansen, S., Womack, J., Scholz, I., Renner, A., Edgel, K. A., Xu, G., Ford, J. C., Grey, M., St. Laurent, B., Turner, J. M., Planer, S., Legasse, A. W., Richie, T. L., Aguiar, J. C., Axthelm, M., Villasante, E. D., Weiss, W., Edlefsen, P. T., Picker, L. & Frueh, K., Jan 1 2019, In : PLoS One. 14, 1, e0210252.

Research output: Contribution to journalArticle

Plasmodium knowlesi
Cytomegalovirus
Sporozoites
T-cells
Parasitemia

Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome

GC6-74 Consortium, Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Tuberculosis
Metabolomics
Transfer RNA Aminoacylation
Metabolome
Transcriptome
1 Citation (Scopus)

Combination adenovirus and protein vaccines prevent infection or reduce viral burden after heterologous clade C simian-human immunodeficiency virus mucosal challenge

Malherbe, D., Mendy, J., Vang, L., Barnette, P. T., Reed, J., Lakhashe, S. K., Owuor, J., Gach, J. S., Legasse, A. W., Axthelm, M., LaBranche, C. C., Montefiori, D., Forthal, D. N., Park, B., Wilson, J. M., McLinden, J. H., Xiang, J., Stapleton, J. T., Sacha, J., Haynes, B. F. & 6 othersLiao, H. X., Ruprecht, R. M., Smith, J., Gurwith, M., Haigwood, N. & Alexander, J., Jan 1 2018, In : Journal of Virology. 92, 2, e01092-17.

Research output: Contribution to journalArticle

Adenovirus Vaccines
Combined Vaccines
Simian Immunodeficiency Virus
Human immunodeficiency virus
Macaca
1 Citation (Scopus)

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

Okoye, A., Hansen, S., Vaidya, M., Fukazawa, Y., Park, H., Duell, D. M., Lum, R., Hughes, C. M., Ventura, A. B., Ainslie, E., Ford, J. C., Morrow, D., Gilbride, R. M., Legasse, A. W., Hesselgesser, J., Geleziunas, R., Li, Y., Oswald, K., Shoemaker, R., Fast, R. & 6 othersBosche, W. J., Borate, B. R., Edlefsen, P. T., Axthelm, M., Picker, L. & Lifson, J. D., Sep 1 2018, In : Nature Medicine. 24, 9, p. 1430-1440 11 p.

Research output: Contribution to journalArticle

Simian Immunodeficiency Virus
Secondary Prevention
Viruses
Cytomegalovirus
Macaca mulatta
2 Citations (Scopus)

Potent immune modulation by medi6383, an engineered human ox40 ligand igg4p fc fusion protein

Oberst, M. D., Auge, C., Morris, C., Kentner, S., Mulgrew, K., McGlinchey, K., Hair, J., Hanabuchi, S., Du, Q., Damschroder, M., Feng, H., Eck, S., Buss, N., de Haan, L., Pierce, A. J., Park, H., Sylwester, A., Axthelm, M., Picker, L., Morris, N. P. & 2 othersWeinberg, A. & Hammond, S. A., May 1 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 1024-1038 15 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Proteins
Cell Proliferation
Neoplasms
Cytokines