Michael Axthelm

Associate Scientist

  • 6131 Citations
  • 38 h-Index
1978 …2020
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Macaca mulatta Medicine & Life Sciences
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Infection Medicine & Life Sciences
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Projects 1978 2020

Expanded SPF Rhesus Macaque Breeding Colony for AIDS Research

Axthelm, M.

National Institutes of Health

8/1/167/31/20

Project: Research projectAnimal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements

Macaca mulatta
Macaca
breeding
Simian immunodeficiency virus
Human immunodeficiency virus

Consortium for AIDS Vaccine Research in Nonhuman Primates

Picker, L., Axthelm, M., Burton, D. R., Johnson, R. P., Shaw, G., Desrosiers, R., Haase, A. T., Sekaly, R. & Barouch, D. H.

National Institutes of Health

7/15/116/30/16

Project: Research projectResearch Program--Cooperative Agreements

Macaca mulatta
Infection
AIDS Vaccines
Primates
Vaccines

Development of an Effector-Memory T Cell AIDS Vaccine

Picker, L., Axthelm, M., Nelson, J., Kahl, C. A., Frueh, K., Sekaly, R., Barry, P. & Fruh, K.

National Institutes of Health

7/15/116/30/17

Project: Research projectResearch Program Projects

AIDS Vaccines
Macaca mulatta
Vaccines
Cytomegalovirus Vaccines
T-Lymphocytes

Pacific NorthWest Regional Center of Excellence (PNWRCE)

Streblow, D., Slifka, M., McWeeney, S., Axthelm, M., Moses, A., Nelson, J., Baric, R., Landfear, S., Nikolich-Zugich, J., Barklis, E., Gale, M., Katze, M., Kawaoka, Y., Bevan, M., Smith, R., Maizels, N., Frueh, K., Labeaud, A. D., Ryman, K., Chanda, S., Galloway, D. A. & Fruh, K.

National Institutes of Health

4/20/092/28/15

Project: Research projectSpecialized Center--Cooperative Agreements

Northwestern United States
National Institute of Allergy and Infectious Diseases (U.S.)
Vulnerable Populations
Research
Bioinformatics

Research Output 1981 2018

  • 6131 Citations
  • 38 h-Index
  • 124 Article

Combination adenovirus and protein vaccines prevent infection or reduce viral burden after heterologous clade C simian-human immunodeficiency virus mucosal challenge

Malherbe, D. C. , Mendy, J. , Vang, L. , Barnette, P. T. , Reed, J. , Lakhashe, S. K. , Owuor, J. , Gach, J. S. , Legasse, A. W. , Axthelm, M. K. , LaBranche, C. C. , Montefiori, D. , Forthal, D. N. , Park, B. , Wilson, J. M. , McLinden, J. H. , Xiang, J. , Stapleton, J. T. , Sacha, J. B. , Haynes, B. F. & 6 others Liao, H. X., Ruprecht, R. M., Smith, J., Gurwith, M., Haigwood, N. L. & Alexander, J., Jan 1 2018, In : Journal of Virology. 92, 2, e01092-17

Research output: Contribution to journalArticle

Adenovirus Vaccines
Combined Vaccines
AIDS Vaccines
Simian Immunodeficiency Virus
Human immunodeficiency virus

Potent immune modulation by medi6383, an engineered human ox40 ligand igg4p fc fusion protein

Oberst, M. D. , Auge, C. , Morris, C. , Kentner, S. , Mulgrew, K. , McGlinchey, K. , Hair, J. , Hanabuchi, S. , Du, Q. , Damschroder, M. , Feng, H. , Eck, S. , Buss, N. , de Haan, L. , Pierce, A. J. , Park, H. , Sylwester, A. , Axthelm, M. K. , Picker, L. , Morris, N. P. & 2 others Weinberg, A. & Hammond, S. A., May 1 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 1024-1038 15 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Proteins
Cell Proliferation
Neoplasms
Cytokines
6 Citations

Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine

Hansen, S. G. , Zak, D. E. , Xu, G. , Ford, J. C. , Marshall, E. E. , Malouli, D. , Gilbride, R. M. , Hughes, C. M. , Ventura, A. B. , Ainslie, E. , Randall, K. T. , Selseth, A. N. , Rundstrom, P. , Herlache, L. , Lewis, M. S. , Park, H. , Planer, S. L. , Turner, J. M. , Fischer, M. , Armstrong, C. & 20 others Zweig, R. C., Valvo, J., Braun, J. M., Shankar, S., Lu, L., Sylwester, A. W., Legasse, A. W., Messerle, M., Jarvis, M. A., Amon, L. M., Aderem, A., Alter, G., Laddy, D. J., Stone, M., Bonavia, A., Evans, T. G., Axthelm, M. K., Früh, K., Edlefsen, P. T. & Picker, L. J., Feb 1 2018, In : Nature Medicine. 24, 2, p. 130-143 14 p.

Research output: Contribution to journalArticle

Cytomegalovirus Vaccines
Macaca mulatta
Tuberculosis
Vaccines
Tuberculosis Vaccines
2 Citations

The Role of MHC-E in T Cell immunity is conserved among humans, rhesus macaques, and cynomolgus macaques

Wu, H. L. , Wiseman, R. W. , Hughes, C. M. , Webb, G. M. , Abdulhaqq, S. A. , Bimber, B. N. , Hammond, K. B. , Reed, J. S. , Gao, L. , Burwitz, B. J. , Greene, J. M. , Ferrer, F. , Legasse, A. W. , Axthelm, M. K. , Park, B. S. , Brackenridge, S. , Maness, N. J. , McMichael, A. J. , Picker, L. J. , O'Connor, D. H. & 2 others Hansen, S. G. & Sacha, J. B., Jan 1 2018, In : Journal of Immunology. 200, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

Simian Acquired Immunodeficiency Syndrome
CD8-Positive T-Lymphocytes
CD4-Positive T-Lymphocytes
Simian Immunodeficiency Virus
Histocompatibility Antigens Class I
9 Citations

Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology

Hirsch, A. J. , Roberts, V. H. J. , Grigsby, P. L. , Haese, N. , Schabel, M. C. , Wang, X. , Lo, J. O. , Liu, Z. , Kroenke, C. D. , Smith, J. L. , Kelleher, M. , Broeckel, R. , Kreklywich, C. N. , Parkins, C. J. , Denton, M. , Smith, P. , Defilippis, V. , Messer, W. , Nelson, J. A. , Hennebold, J. D. & 12 others Grafe, M., Colgin, L., Lewis, A., Ducore, R., Swanson, T., Legasse, A. W., Axthelm, M. K., MacAllister, R., Moses, A. V., Morgan, T. K., Frias, A. E. & Streblow, D. N., Dec 1 2018, In : Nature Communications. 9, 1, 263

Research output: Contribution to journalArticle

viruses
infectious diseases
Fetal Development
Macaca mulatta
Viruses