Jonathan Pruneda

Assistant Professor

  • 1145 Citations
  • 16 h-Index
1980 …2019
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  • 6 Similar Profiles
Ubiquitin Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences
Ligases Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Ubiquitin-Conjugating Enzymes Medicine & Life Sciences
Conformations Chemical Compounds
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1980 2015

SYNCHROTRON RADIATION BIOTECHNOLOGY

Blackburn, N., Blackburn, N., Blackburn, N., Hall, S. (., Phizackerley, P., Boxer, S., Suresh, S., Bernstein, B., Scavetta, R., Borhani, D., Kuhn, P., Alechine, A., Pohl, E., Pelletier, H., Laporte, S., Irving, T., Deisenhofer, J., Delarue, M., Holbrook, S., Chen, Y., Fletterick, R., Rosenzweig, A., Goodwill, K. E. N., Sage, C., Kim, K., Sundaramoorthy, M., Bergmann, U. W. E., Narayana, N., Enemark, J., Hart, P., Tiede, D., Olah, G., Unknown, [. V., Neidigh, K., Ying, S., Hwang, P., Gardea-Torresdey, J., Kiefhaber, T., Bjorkman, P., [No Value], K. R., Kirk, M., Keenan, R., Mondrag, A., Chiu, W. A. H., Chen, P., Rupp, B., Greenwald, J., Louie, G., Brinen, L., Ranganathan, R., Whitlow, M. D., Hung, L., Schuller, D., Joseph, J., Butte, M., Brudler, R., Beernink, P., Bargar, J., Raman, C., Rabedeau, T., George, M., Terry, N., Rosenfeld, R., Borgstahl, G., Bellamy, H., Iacovoni, J., Salerno, C., Plaxco, K. W., Bhaskar, B., Feher, G., Phizackerley, R. P., Ellis, P., Nautiyal, S., Rehr, J., Silberg, J., Morel, F., Knapp, M., Bott, R., Zhang, Z., Haas, E., Reiling, K., Borngraber, S., Firestone, M., Poulos, T. L., Geistlinger, T., Wilson, C., Zubieta, C., Jurnak, F., Frydman, J., Blanchard, H., Kamata, K., Williams, P., Stroud, R., Martin, J., Mazlo, J., Sevrioukova, I., Huff, C., Bingdong, S., Xuong, N., Gray, H., Robinson, R., Barondeau, D., Baldwin, E., Seungil, H., Orville, A., Funke, P., [No Value], Q., Verdecia, M., Plecs, J., Yu, E., Nguyen, J., Perona, J. J., Miller, M., Cupp-Vickery, J., Yanshun, L., Hosfield, D., Cheng, X., Sussman, D., Lacy, B., Antonysamy, S., MacHius, M., Bergmann, E., Pickering, J., Daniels, D., Everse, S., Holton, J., Harris, S., Peters, J., Cecchini, G., Usher, K., Akamine, P., Su, L. I., Bringer, A., Hausrath, A., Wilcox, S., Sagermann, M., Kresge, N., van Roey, P., Zhang, H., Stroupe, M. B., Steussy, N. I. C., Hirsch, J., Aevarsson, A., Baker, D., Hosfield, C., Rose, R., Strynadka, N., Wang, Z., Zhang, M. A. N., Leighton, T., McWhirter, S., Martinez, S., Prasad, S., Brennan, R. G., Finer-Moore, J. S., Ybe, J., Kim, K., McPhillips, T., Fisher, A., Shaw, A., Prosise, G., Sindelar, C., Parikh, S., Kovall, R., Cramer, S. P., Stevens, R., Parge, H., Mol, C., Wilson, I., Penner-Hahn, J. E., Foster, P., Borhani, D., Redinbo, M., Putnam, C., Lay, P., Kuhn, P., Wagner, R., Pohl, E., Irving, T., Deisenhofer, J., Choe, S., Merritt, E., Delarue, M., Chen, J., Lippard, S., Rudenko, G., Jardetzky, T., Fink, A., Genick, U., Skidmore, M., Safinya, C., Rosenzweig, A., Rayment, I., Shiau, A., Sauter, N., Stenkamp, R., Dewitt, J., Luecke, H., Crane, B., Doolittle, R., Arvai, A., Sundaramoorthy, M., Huang, L. A. N., Anderson, A. C., Huiying, L., Horjales, E., Focia, P., Stezowski, J., Bergmann, U. W. E., Endrizzi, J., Burgess, B., Narayana, N., Enemark, J., Prince, R., Tiede, D., Olah, G., Hedman, B., Vickery, L., Waksman, G., Rees, D., Scott, R., Kiefhaber, T., Bjorkman, P., [No Value], K. R., Salt, D., George, G., Wiener, M. C., Marks, C., David, P., Kirk, M., Keenan, R., Tsuruta, H., McKay, D., De Vos, A., Chiu, W. A. H., Hill, C. P., Chen, P., Rupp, B., Mendelson, R., Lo, T., Trewhella, J., Yeh, J., Soltis, S., Solomon, E., Ming, L., Starks, C., Thayer, M., Guan, Y. U. E., Stout, C., Rutenber, E., Klein, M., Varughese, K., Baker, E., Crowder, S., Warburton, W., Greenwald, J., Yonath, A., Berry, E., Johnson, J., Templeton, D., Curmi, P., Riggs-Gelasco, P., Weis, W., Doniach, S., Bruns, C., Brinen, L., Whitlow, M. D., Freymann, D., Einspahr, H., Bilwes, A., Schuller, D., Suresh, S., Gillmor, S., Bernstein, B., Han, G., Bourne, Y., Scavetta, R., Amzel, L., Harrison, S., Terwilliger, T. C., Redford, S., Alechine, A., Buchbinder, J., Pelletier, H., Laporte, S., Schafmeister, C., Gatewood, J. M., Jennings, P., Sablin, E., McTigue, M., Holbrook, S., Chen, Y., Frederick, C., Lattman, E., Raghunathan, S., Vivien, Y., Somoza, J., Fletterick, R., Korolev, S., Fields, B., Stowell, M., Hendle, J., Sage, C., Kim, K., Hellinga, H. W., Edwards, A., Hidong, K., Hales, B., Yu, C., Hart, P., Forest, K., Freeman, H., Rader, S., Almo, S. C., Sawaya, M., Eisenberg, D., Friedman, R. M., Neidigh, K., Ying, S., Hwang, P., Gardea-Torresdey, J., Adams, M. W., Lee, J., Ralston, C., Smith, T., Edwards, S., Lawrence, M., Kim, S., Rich, A., Mondragsn, A., Nelson, H., Kull, F., Lin, K. A. I., Canady, M., Louie, G., Grush, M., Whitby, F., Hogle, J., Fu, J., Ranganathan, R., Izard, T., Hackert, M., Hung, L., Aoyagi, M., Sonnenburg, E. D., McRee, D. E., Terry, N., Craig, L., Bhaskar, B., Garcin, E., Wallace, E., Ellis, P., Guss, M., Robert, B., Licata, V., Detitta, G., Balendiran, G., McPhillips, T. M., Latimer, M., Pickering, I. J., Borglin, S., Sevrioukova, I. F., Julie, H., Focia, P., Tubbs, J., Didonato, M., Larsen, E., Verdecia, M., Juers, D. H., Yang, X., Austin, M., Kornfield, J., Chan, D., Drennan, C., Salt, D., Daniels, D., Egea, P. F., Chiu, W. A. H., Schumacher, M., Stroupe, M. B., Carmel, A., Russo, D., Freymann, D. M., Randal, M., Swairjo, M., Strynadka, N., Riggs-Gelasco, P., Doniach, S., Vrielink, A., Goodin, D. B., Whitlow, M. D., Roosild, T., Shiou-Chuan, T., Wood, T., Smolsky, I. L., Hirsch, G., Kazuki, I., Cohen, A., Garcia, K. C., Wilson, M., Maher, M., Fink, A., Sundaresan, V., Herschlag, D., Montfort, W. R., Lanyi, J., Feher, G., Ross, J., Bjorkman, P., Baker, E., Brennan, R. G., Redinbo, M., Richard, S., Rosenzweig, A., Zhang, K., Nichol, H., Chan, M., Peters-Libeu, C., Rehr, J., Baldwin, E., Perona, J. J., Liddington, R., Scott, W., Varughese, K., Stevens, R., Eigenbrot, C., Schimmel, P., Wilson, I., Penner-Hahn, J. E., Raman, C., Rabedeau, T., George, M., Kantrowitz, E., Snell, E., Wilson, D., Lippard, S., Safinya, C., Yachandra, V. K., Getzoff, E., Stout, T., Stenkamp, R., De Beer George, S., Barondeau, D., Huiying, L., Gonzalez, A., Bussiere, D., Khosla, C., Hedman, B., Mooers, B., Bushnell, D., Fee, J., Horton, N., Rees, D. C., Scott, R., Stemmler, T. L., George, G., Tsuruta, H., McKay, D., Peters, J., Deacon, A. M., Soltis, S., Lawrence, Q., Ming, L., Stout, C., Brunger, A. T., Johnson, J., Weis, W., Murphy, M., Chang, G., Fisher, A., Kornberg, R., Mathews, I., Jude, K., Miller, G. A., He, M., Harrington, D., Schulze-Gahmen, U., Ailong, K., Benfatto, M., [No Value], W. G. J., Shafer, R., Luening, K., Krishnamoorthy, T., Stroud, R., Harbury, P., Villasenor, A., Shen, W., Yamagata, A., Cingolani, G., Bracey, M., Rosengarth, A., Genick, U., Vickery, J., Ghosh, P., Jordan, S., Cate, J., MacKinnon, R., Berry, E., Andrews, J., Choe, S., Kang, C., Gardea-Torresdey, J., Snell, G., Tsai, S., Ping, L., Brejc, K., Jalilehvand, F., Smith, C., Kennepohl, P., Brzustowicz, M., Noller, H., Lawrence, C. M., Green, M. T., Brinen, L., George, S., Aoyagi, M., Joost, P. H., Wimberly, B., Craig, L., Coleman, R., Kieft, J., Doolittle, R., Sevrioukova, I. F., Schulman, H., Julie, H., Focia, P., Hocking, R., Tubbs, J., Didonato, M., Verdecia, M., Juers, D. H., Morse, D., Egea, P. F., Jianghai, Z., Moriyama, H., Trewhella, J., Harris, H., Hjelm, R., Pingitore, N., Kenneth, N., Walter, M., Goodin, D. B., Lewis, H. A. L., Lay, P., Terry, N., Kihara, H., Baker, K., Remington, S. J., Somoza, J., Poulos, T. L., Kreusch, A., Hitomi, K., Noel, J., Matsuda, S., Weiss, A., Bullitt, E., Guss, J. M., Hur, S. U. N., Wakatsuki, S., Schreiter, E., Austin, M., Ralston, C., Salt, D., Kirk, M., Kim, S., Huang, Z., Foster, A., Bubacco, L., Russo, D., Freymann, D. M., Knighton, D., Curmi, P., Doniach, S., Mondragon, A., Tierney, D., Kuriyan, J., Salom Arbona, D., Chih-Chia, S., Warner, J., Neese, F., Luhmann, N., Stewart, L., Stec, B., Sundaramoorthy, M., Mattison, K., Zhang, Q., Bergmann, E., Parsons, J., Allen, J. P., Niebuhr, M., Noveron, J., Ikonen, T., Pojer, F., Strynadka, N., Arai, Y., Whitlow, M. D., Matthews, B., Prosise, G., Licata, V., Detitta, G., Doonan, C., [No Value], K. R., Nilsson, A., Schumacher, M., Agard, D., Goldenberg, D. N., Wakabayashi, K., Vrielink, A., Romanowski, M., McRee, D. E., Knobler, C., Bott, R., Newcomer, M. E., Pathuri, P., Balendiran, G., Carr, P., Carroll, K., Lee, S., Frydman, J., Tang, K., Auldridge, M., Kang, S. W. A., Jessica, V., Szilagyi, R. K., Kuhn, P., Wong, G., Quake, S., Latimer, M., Pickering, I. J., Maroney, M., Iverson, T., Stagno, J., Zamble, D., Pozharskiy, E., Bergmann, U. W. E., Malkowski, M., Turley, S., Yang, X., Hurley, J. B., Hill, C. P., Saphire, E. O., Solomon, E., Tang, Y. I., Swairjo, M., Riggs-Gelasco, P., Okamura, M., Groppe, J. C., Barry, C., van Petegem, F., Matsudaira, P. T., Mang, Y., Allen, K. N., O'Connor, D., Takagi, Y., Perez-Mendez, L., Murr, M., Daniel, L., Prach, L., Nimigean, C. M., Wenqing, X., Lemieux, J., Gouaux, J. E., Berger, J., Keatinge-Clay, A., Lee, T., Chen, X., Flynn, E., Streli, C., Chen, Y. U., Lamers, M., Lombana, T. N., Maris, A. N. N., Cunningham, E., Fraser, J., Ho Leung, N., Jacobs, M., Mieczkowski, C., Lacy, D. B., Gay, L., Kanai, S., Vigers, A., Zhou, Y., Baer, C., Alber, T., Gee, C., Spraggon, G., Anderson, M., Grundner, C., Scott, P., Fenton, A., Rosen, B. P., Jedrzejas, M., Roberts, S., Maduke, M., Frei, H., Nowakowski, J., Merritt, E., Weiss, T., Wedekind, J., Hidong, K., Nettles, K., Stubbs, G., Sutton, R., Garcia, K. C., McFarlane, K., Kohzuma, T., Brayer, G., Kelly, M., Roosild, T., Singh, S., Cohen, A., Hung, L., Clemons, W. M., Jensen, G., Junjun, G., Coleman, R., Blanchard, H., Stephenson, S., Pianetta, P., Lee, J., Froester, F., Carter, A. J., Lam, P., Abendroth, J. A. N., Tari, L., Lindhout, D., Wilce, M., Lingel, A., Kuglstatter, A., MacHeboeuf, P., Hansel, C., Kinney, J. H., Roca, A., Craig, L., Rosenfeld, R., Metcalf, P., Habel, L., Gupta, K., Choe, J., Doukov, T., Marcu, O., Eun-Young, K., Kantardjieff, K., Jardetzky, T., Reichow, S. L., Wasinger, E., Bateman, K., Boulanger, M., Goulding, C., Zajonc, D., Sevrioukova, I., Qing, H., Tezcan, F. A., Lograsso, P., Ozorowski, G., Tang, L., Blumenthal, D., Peisley, A., McNulty, R., Sproules, S., Sagermann, M., Holyoak, T., Pazicni, S., Kuske, C., Goodin, D. B., Brandt, G., Gouaux, J., Jungwook, K., Prach, L. M., Kerkow, D., Abbate, E., Palmer, A., Earnest, T., Card, G., Jayaraman, S., van Den Akker, F., Lay, P., Garcin, E., Changgong, L., van Petegem, F., Aniruddha, D., Viadiu, H., Kwiatkowski, W., Tung-Chung, M., Lee, K., He, M., Rubin, S. M., Lancaster, K., Wilbanks, S., Jing, H. U. A., Soutter, H., Stasser, J., Rexach, M., Webb, S., Nicholas Graham, F., Chaudhuri, B., Waters, D., Goldman, P., Louie, M., Bertin, A., Scott, E., Harris, H., Brock, J. S., Curmi, P., Kenneth, N., Patty, C. A., Sarangi, S., Tsai, C., Walter, M., Izard, T., Lieh Yoon, L., Zhang, Y. A. N., Yang, K., Huajun, F., Fortoul, T., Bingdong, S., Sousa, M. C., Zongchao, J., Schaible, E., Fenn, R. S., Liu, X. I. N., Pushie, M. J., Lyubimov, A., Xuan-Zheng, S., Chuenchor, W., Mangani, S., Kielkopf, C., Punshon, T., Clemons, W. M., Johnson, S., Betts, L., Oganesyan, V., dervan, P., MacRae, I. J., Vakulenko, S., Ficko-Blean, E., Hamaoka, B. Y., Martel, A., Subramaniapillai, K., Mayo, S., Cherezov, V. G., Changping, Z., Fu, L. I., Joubert, L., Tian, S., Della Longa, S., Gray, H., Bosch, J. P., Stoltz, B., Hjelm, R. P., Zheng, J. C., Tang, P. E. I., Pushkar, K., Wilmot, C. M., Arnold, F., Holman, K. M., Tong, L., Bercaw, J., Schultz, W., Palmer, J. H., Guan, L. A. N., Chan, D., Fuller, G., Bjorkman, P., Herschlag, D., Porta, J., Grossman, J. G., Sazinsky, M., Barton, J., Voegtli, W., Harris, S., Xu, H. E., Wang, D., Sali, A., Zhang, C., Meyer-Klaucke, W., Dong, B., Mijovilovich, A. N. A., Gulick, A., Doniach, S., Menichelli, E. R. A., Williams, J. C., Higgins, K. A., Grubbs, R. H., Gerratana, B., Carter, L., Wang, Y., Stevens, J., Zhu, J. I., Wang, X., Jennings, P., Cody, V., Lemieux, M. J., Pruneda, J., Lilyestrom, W. G., Matsui, T., Meng-Chiao, H., Ho, S., Zuber, H., Black, F., White, M. A., Wolfe-Simon, F., Weng, T., Tang, M., Reese, M. L., Rajagopal, P., Nichol, H., Rongsheng, J., Angel, L., Saltzberg, D., McCormick, M., Guo, M. I. N., Seelig, B., Luger, K., Yongqun, H., Nicholas, H., Stahanam, N., Schick, B., Cherbavaz, D., Irving, C., Hadman, B., Perry, K., Powers, L., Nanni, R., Mande, S., Brunger, A., Elder, R., Anthony, C., Ramalingam, V., Mylvaganam, S., Gillmor, S., Cramer, S. P., Stevens, R., Parge, H., Mol, C., Wilson, I., Han, G., Bourne, Y., Penner-Hahn, J. E., Amzel, L., Foster, P., Harrison, S., Redinbo, M., George, M., Putnam, C., Lay, P., Terwilliger, T. C., Bellamy, H., Redford, S., Wagner, R., Buchbinder, J., Phizackerley, R. P., Schafmeister, C., Gatewood, J. M., Jennings, P., Rehr, J., Sablin, E., Choe, S., Merritt, E., Chen, J., McTigue, M., Lippard, S., Rudenko, G., Jardetzky, T., Frederick, C., Fink, A., Lattman, E., Raghunathan, S., Vivien, Y., Pickering, I. J., Genick, U., Somoza, J., Korolev, S., Skidmore, M., Safinya, C., Rayment, I., Shiau, A., Fields, B., Sauter, N., Stenkamp, R., Stowell, M., Hendle, J., Dewitt, J., Luecke, H., Crane, B., Doolittle, R., Arvai, A., Hellinga, H. W., Huang, L. A. N., Anderson, A. C., Huiying, L., Horjales, E., Focia, P., Edwards, A., Stezowski, J., Hidong, K., Endrizzi, J., Burgess, B., Hales, B., Yu, C., Prince, R., Forest, K., Freeman, H., Rader, S., Almo, S. C., Sawaya, M., Hedman, B., Vickery, L., Waksman, G., Eisenberg, D., Friedman, R. M., Rees, D., Scott, R., Adams, M. W., Lee, J., Ralston, C., Salt, D., Smith, T., George, G., Edwards, S., Wiener, M. C., Marks, C., David, P., Lawrence, M., Tsuruta, H., McKay, D., Kim, S., De Vos, A., Hill, C. P., Mendelson, R., Rich, A., Lo, T., Trewhella, J., Yeh, J., Soltis, S., Solomon, E., Ming, L., Starks, C., Thayer, M., Nelson, H., Kull, F., Lin, K. A. I., Guan, Y. U. E., Stout, C., Canady, M., Rutenber, E., Klein, M., Varughese, K., Baker, E., Crowder, S., Warburton, W., Yonath, A., Berry, E., Johnson, J., Templeton, D., Curmi, P., Riggs-Gelasco, P., Weis, W., Doniach, S., Grush, M., Bruns, C., Whitby, F., Hogle, J., Fu, J., Izard, T., Freymann, D., Einspahr, H., Bilwes, A., Hackert, M., McRee, D. E., Skinner, M., Mondragon, A., Goodwill, K., Hodgson, K. & Pruneda, J.

National Institutes of Health

3/1/802/28/15

Project: Research project

synchrotron radiation
Copper
oxygen metabolism
nitrogenation
copper

Research Output 2008 2019

Evaluating enzyme activities and structures of DUBs

Pruneda, J. & Komander, D., Jan 1 2019, Methods in Enzymology. Academic Press Inc., p. 321-341 21 p. (Methods in Enzymology; vol. 618).

Research output: Chapter in Book/Report/Conference proceedingChapter

Enzyme activity
Ubiquitin
Enzymes
Substrates
Viruses

Insights into ubiquitin chain architecture using Ub-clipping

Swatek, K. N., Usher, J. L., Kueck, A. F., Gladkova, C., Mevissen, T. E. T., Pruneda, J., Skern, T. & Komander, D., Aug 22 2019, In : Nature. 572, 7770, p. 533-537 5 p.

Research output: Contribution to journalLetter

Ubiquitin
Polyubiquitin
Ubiquitination
Mitochondrial Degradation
Dipeptides

Legionella dismantles linear ubiquitin

Damgaard, R. B. & Pruneda, J., Aug 1 2019, In : Nature Microbiology. 4, 8, p. 1244-1245 2 p.

Research output: Contribution to journalArticle

Legionella
Ubiquitin
Legionnaires' Disease
Legionella pneumophila
Bacterial Infections
3 Citations (Scopus)

A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation

Pruneda, J., Bastidas, R. J., Bertsoulaki, E., Swatek, K. N., Santhanam, B., Clague, M. J., Valdivia, R. H., Urbé, S. & Komander, D., Dec 1 2018, In : Nature Microbiology. 3, 12, p. 1377-1384 8 p.

Research output: Contribution to journalLetter

Chlamydia
Acetylation
Neglected Diseases
Chlamydia Infections
Acetyltransferases
72 Citations (Scopus)

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal

DaRosa, P. A., Wang, Z., Jiang, X., Pruneda, J., Cong, F., Klevit, R. E. & Xu, W., Jan 1 2018, In : Nature. 517, 7533

Research output: Contribution to journalArticle

Ubiquitination
Ligases
Ubiquitin
Adenosine Diphosphate
Adenosine Diphosphate Ribose