John Williams

Professor

  • 13066 Citations
  • 63 h-Index
1976 …2020
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Fingerprint Dive into the research topics where John Williams is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 27 Similar Profiles
Locus Coeruleus Medicine & Life Sciences
Neurons Medicine & Life Sciences
Opioid Analgesics Medicine & Life Sciences
Opioid Receptors Medicine & Life Sciences
Dopaminergic Neurons Medicine & Life Sciences
Morphine Medicine & Life Sciences
Dopamine Medicine & Life Sciences
Potassium Medicine & Life Sciences

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Projects 1987 2020

Cocaine
Neurons
Dopamine
Ventral Tegmental Area
Locus Coeruleus
Mesencephalon
gamma-Aminobutyric Acid
Opioid Analgesics
Afferent Pathways
Dopaminergic Neurons
mu Opioid Receptor
Opioid Analgesics
HEK293 Cells
Pharmacology
Pain Clinics

Research Output 1976 2019

  • 13066 Citations
  • 63 h-Index
  • 178 Article
  • 2 Conference contribution
  • 1 Review article
3 Citations (Scopus)

Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects

Kliewer, A., Schmiedel, F., Sianati, S., Bailey, A., Bateman, J. T., Levitt, E. S., Williams, J., Christie, M. J. & Schulz, S., Dec 1 2019, In : Nature Communications. 10, 1, 367.

Research output: Contribution to journalArticle

analgesia
phosphorylation
Phosphorylation
Opioid Receptors
GTP-Binding Proteins
4 Citations (Scopus)

Cellular tolerance at the µ-opioid receptor is phosphorylation dependent

Arttamangkul, S., Heinz, D. A., Bunzow, J. R., Song, X. & Williams, J., Mar 28 2018, In : eLife. 7, e34989.

Research output: Contribution to journalArticle

Phosphorylation
Opioid Receptors
Morphine
Wild Animals
Locus Coeruleus

Desensitization and Tolerance of Mu Opioid Receptors on Pontine Kölliker-Fuse Neurons

Levitt, E. S. & Williams, J., Jan 1 2018, In : Molecular Pharmacology. 93, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

mu Opioid Receptor
Neurons
Locus Coeruleus
Morphine
Opioid Analgesics
12 Citations (Scopus)

The Evolving Understanding of Dopamine Neurons in the Substantia Nigra and Ventral Tegmental Area

Gantz, S. C., Ford, C. P., Morikawa, H. & Williams, J., Feb 10 2018, In : Annual Review of Physiology. 80, p. 219-241 23 p.

Research output: Contribution to journalReview article

Ventral Tegmental Area
Dopaminergic Neurons
Substantia Nigra
Population
Neurochemistry
47 Citations (Scopus)

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

Patriarchi, T., Cho, J. R., Merten, K., Howe, M. W., Marley, A., Xiong, W-H., Folk, R. W., Broussard, G. J., Liang, R., Jang, M. J., Zhong, H., Dombeck, D., von Zastrow, M., Nimmerjahn, A., Gradinaru, V., Williams, J. & Tian, L., May 31 2018, (Accepted/In press) In : Science. p. 1-14 14 p.

Research output: Contribution to journalArticle

Dopamine
Optogenetics
Learning
Melatonin
Neuropeptides