John Morrison

Professor

  • 5385 Citations
  • 42 h-Index
1982 …2020
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Research Output 1982 2019

  • 5385 Citations
  • 42 h-Index
  • 113 Article
  • 5 Chapter
  • 1 Letter
  • 1 Review article
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Article
2019

Evaluating changes of blood flow in retina, choroid, and outer choroid in rats in response to elevated intraocular pressure by 1300 nm swept-source OCT

Xu, J., Li, Y., Song, S., Cepurna, W., Morrison, J. & Wang, R. K., Jan 1 2019, In : Microvascular Research. 121, p. 37-45 9 p.

Research output: Contribution to journalArticle

Choroid
Intraocular Pressure
Retina
Rats
Optical tomography
2018

A Methodology for Individual-Specific Modeling of Rat Optic Nerve Head Biomechanics in Glaucoma

Schwaner, S. A., Kight, A. M., Perry, R. N., Pazos, M., Yang, H., Johnson, E. C., Morrison, J. C., Burgoyne, C. F. & Ross Ethier, C., Aug 1 2018, In : Journal of Biomechanical Engineering. 140, 8, 084501.

Research output: Contribution to journalArticle

Biomechanics
Optic Disk
Biomechanical Phenomena
Glaucoma
Rats
3 Citations

Automated spectroscopic retinal oximetry with visible-light optical coherence tomography

Pi, S., Camino, A., Cepurna, W., Wei, X., Zhang, M., Huang, D., Morrison, J. & Jia, Y., May 1 2018, In : Biomedical Optics Express. 9, 5, p. 2056-2067 12 p., #320440.

Research output: Contribution to journalArticle

oximetry
Oximetry
Optical Coherence Tomography
tomography
Oxygen

Brinzolamide-induced Follicular Conjunctivitis

Young, J. W., Clements, J. L., Morrison, J. & Takusagawa, H., Jan 1 2018, (Accepted/In press) In : Journal of Glaucoma.

Research output: Contribution to journalArticle

Conjunctivitis
brinzolamide

Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT

Wei, X., Camino, A., Pi, S., Cepurna, W., Huang, D., Morrison, J. C. & Jia, Y., May 1 2018, In : Optics Letters. 43, 9, p. 2204-2207 4 p.

Research output: Contribution to journalArticle

standard deviation
tomography
retinal images
angiography
phase shift

In Vivo Small Molecule Delivery to the Optic Nerve in a Rodent Model

Tehrani, S., Delf, R. K., Cepurna, W. O., Davis, L., Johnson, E. C. & Morrison, J. C., Dec 1 2018, In : Scientific Reports. 8, 1, 4453.

Research output: Contribution to journalArticle

Optic Disk
Optic Nerve
Rodentia
Actins
Optic Nerve Diseases

Rodent retinal circulation organization and oxygen metabolism revealed by visible-light optical coherence tomography

Pi, S., Camino, A., Wei, X., Simonett, J., Cepurna, W., Huang, D., Morrison, J. & Yali, J., Nov 1 2018, In : Biomedical Optics Express. 9, 11, p. 5851-5862 12 p., #345706.

Research output: Contribution to journalArticle

oxygen metabolism
Ophthalmology
ophthalmology
Microcirculation
rodents
4 Citations

The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography

Jiang, X., Johnson, E., Cepurna, W., Lozano, D., Men, S., Wang, R. K. & Morrison, J., Jan 1 2018, In : Microvascular Research. 115, p. 12-19 8 p.

Research output: Contribution to journalArticle

Angiography
Optical tomography
Optical Coherence Tomography
Intraocular Pressure
Animals
2017
5 Citations

Angiographic and structural imaging using high axial resolution fiber-based visible-light OCT

Pi, S., Camino, A., Zhang, M., Cepurna, W., Liu, G., Huang, D., Morrison, J. & Jia, Y., Oct 1 2017, In : Biomedical Optics Express. 8, 10, p. 4595-4608 14 p., #304064.

Research output: Contribution to journalArticle

retina
rats
Retina
chickens
embryos
2 Citations
retina
edge detection
Optic Disk
Optical Coherence Tomography
Retina
8 Citations

Biological aspects of axonal damage in glaucoma: A brief review

Tamm, E. R., Ethier, C. R., Dowling, J. E., Downs, C., Ellisman, M. H., Fisher, S., Fortune, B., Fruttiger, M., Jakobs, T., Lewis, G., Mitchell, C. H., Morrison, J., Sharma, S. C., Sigal, I., Sofroniew, M., Wang, L., Wiggs, J., Wu, S. & Masland, R. H., Jan 22 2017, (Accepted/In press) In : Experimental Eye Research.

Research output: Contribution to journalArticle

Optic Disk
Glaucoma
Intraocular Pressure
Sclera
Astrocytes
7 Citations

Comparison of microRNA expression in aqueous humor of normal and primary open-angle glaucoma patients using PCR arrays: A pilot study

Jayaram, H., Phillips, J. I., Lozano, D. C., Choe, T. E., Cepurna, W. O., Johnson, E., Morrison, J., Gattey, D. M., Saugstad, J. & Keller, K., Jun 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 7, p. 2884-2890 7 p.

Research output: Contribution to journalArticle

Aqueous Humor
MicroRNAs
Polymerase Chain Reaction
Primary Open Angle Glaucoma
Encyclopedias
20 Citations

Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma

Takusagawa, H. L., Liu, L., Ma, K. N., Jia, Y., Gao, S. S., Zhang, M., Edmunds, B., Parikh, M., Tehrani, S., Morrison, J. C. & Huang, D., 2017, (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Glaucoma
Blood Vessels
Angiography
Visual Fields
2016
7 Citations

A period of controlled elevation of IOP (CEI) produces the specific gene expression responses and focal injury pattern of experimental rat glaucoma

Morrison, J. C., Cepurna, W. O., Tehrani, S., Choe, T. E., Jayaram, H., Lozano, D. C., Fortune, B. & Johnson, E. C., Dec 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 15, p. 6700-6711 12 p.

Research output: Contribution to journalArticle

Optic Disk
Glaucoma
Gene Expression
Optic Nerve
Wounds and Injuries
9 Citations

Astrocyte structural and molecular response to elevated intraocular pressure occurs rapidly and precedes axonal tubulin rearrangement within the optic nerve head in a rat model

Tehrani, S., Davis, L., Cepurna, W. O., Choe, T. E., Lozano, D. C., Monfared, A., Cooper, L., Cheng, J., Johnson, E. C. & Morrison, J. C., Nov 1 2016, In : PLoS One. 11, 11, e0167364.

Research output: Contribution to journalArticle

astrocytes
Optic Disk
Tubulin
optics
tubulin
14 Citations

Compensation for reflectance variation in vessel density quantification by optical coherence tomography angiography

Gao, S. S., Jia, Y., Liu, L., Zhang, M., Takusagawa, H. L., Morrison, J. C. & Huang, D., Aug 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4485-4492 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Angiography
Noise
Optic Disk
Blood Vessels
8 Citations

Expansions of the neurovascular scleral canal and contained optic nerve occur early in the hypertonic saline rat experimental glaucoma model

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E. C., Morrison, J. C. & Burgoyne, C. F., Apr 1 2016, In : Experimental Eye Research. 145, p. 173-186 14 p.

Research output: Contribution to journalArticle

Optic Nerve
Glaucoma
Theoretical Models
Optic Disk
Nerve Expansion
13 Citations

Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism

Teotia, P., Chopra, D. A., Dravid, S. M., Van Hook, M. J., Qiu, F., Morrison, J., Rizzino, A. & Ahmad, I., 2016, (Accepted/In press) In : Stem Cells.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Retinal Ganglion Cells
Stem Cells
Induced Pluripotent Stem Cells
Embryonic Stem Cells
2 Citations
Optical Coherence Tomography
Glaucoma
Nerve Fibers
Visual Field Tests
Optic Disk
2015
6 Citations

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy

Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I., Jun 1 2015, In : Stem Cells. 33, 6, p. 1743-1758 16 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Induced Pluripotent Stem Cells
Glaucoma
Ocular Hypertension
Acids
12 Citations
Optical tomography
Optical Coherence Tomography
Intraocular Pressure
Rats
Blood
15 Citations

Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene

Ying, H. H., Turturro, S. S., Nguyen, T. T., Shen, X. X., Zelkha, R. R., Johnson, E. E. C., Morrison, J. J. C. & Yue, B. B. Y. J. T., May 6 2015, In : BMC Cell Biology. 16, 1, 14.

Research output: Contribution to journalArticle

Autophagy
Proteasome Endopeptidase Complex
Ubiquitin
Retinal Ganglion Cells
Fluorescence
2 Citations

Introduction to special issue on glaucomatous optic neuropathy: In vivo models and techniques

Ethier, C. R., Morrison, J. C. & Clark, A. F., Jul 20 2015, In : Experimental Eye Research. 141, p. 1-2 2 p.

Research output: Contribution to journalArticle

Animal Disease Models
Optic Nerve Diseases
Optic Nerve
Intraocular Pressure
Glaucoma
13 Citations

MicroRNA expression in the glaucomatous retina

Jayaram, H., Cepurna, W. O., Johnson, E. C. & Morrison, J. C., Dec 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 13, p. 7971-7982 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Retina
Intraocular Pressure
Central Nervous System
Chemical Databases
16 Citations

Modeling glaucoma in rats by sclerosing aqueous outflow pathways to elevate intraocular pressure

Morrison, J. C., Cepurna, W. O. & Johnson, E. C., Mar 28 2015, In : Experimental Eye Research. 141, p. 23-32 10 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Glaucoma
Aqueous Humor
Optic Disk
Injections
201 Citations

Optical coherence tomography angiography of the peripapillary retina in glaucoma

Liu, L., Jia, Y., Takusagawa, H. L., Pechauer, A. D., Edmunds, B., Lombardi, L., Davis, E., Morrison, J. C. & Huang, D., Sep 1 2015, In : JAMA Ophthalmology. 133, 9, p. 1045-1052 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Glaucoma
Retina
Angiography
Perfusion
21 Citations

Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye

Lu, W., Hu, H., Sévigny, J., Gabelt, B. T., Kaufman, P. L., Johnson, E. C., Morrison, J. C., Zode, G. S., Sheffield, V. C., Zhang, X., Laties, A. M. & Mitchell, C. H., 2015, In : Investigative Ophthalmology and Visual Science. 56, 5, p. 3075-3083 9 p.

Research output: Contribution to journalArticle

Glaucoma
Primates
Adenosine Triphosphate
Astrocytes
Retinal Neurons
10 Citations

Rat optic nerve head anatomy within 3D histomorphometric reconstructions of normal control eyes

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E. C., Morrison, J. C. & Burgoyne, C. F., Oct 1 2015, In : Experimental Eye Research. 139, p. 1-12 12 p.

Research output: Contribution to journalArticle

Bruch Membrane
Optic Disk
Anatomy
Retinal Vein
Sclera
2014
20 Citations

An acute intraocular pressure challenge to assess retinal ganglion cell injury and recovery in the mouse

Crowston, J. G., Kong, Y. X. G., Trounce, I. A., Dang, T. M., Fahy, E. T., Bui, B. V., Morrison, J. C. & Chrysostomou, V., Dec 12 2014, In : Experimental Eye Research. 141, p. 3-8 6 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Intraocular Pressure
Wounds and Injuries
Neuroglia
Glaucoma
16 Citations
Optic Disk
Astrocytes
Glaucoma
Actins
Optic Nerve
285 Citations

Optical coherence tomography angiography of optic disc perfusion in glaucoma

Jia, Y., Wei, E., Wang, X., Zhang, X., Morrison, J. C., Parikh, M., Lombardi, L. H., Gattey, D. M., Armour, R. L., Edmunds, B., Kraus, M. F., Fujimoto, J. G. & Huang, D., 2014, In : Ophthalmology. 121, 7, p. 1322-1332 11 p.

Research output: Contribution to journalArticle

Optic Disk
Optical Coherence Tomography
Glaucoma
Angiography
Perfusion
10 Citations
Optic Nerve
Intraocular Pressure
Radiation
Wounds and Injuries
Glaucoma
2013
14 Citations

Electronic health record systems in ophthalmology: Impact on clinical documentation

Sanders, D. S., Lattin, D. J., Read-Brown, S., Tu, D. C., Wilson, D. J., Hwang, T. S., Morrison, J. C., Yackel, T. R. & Chiang, M. F., Sep 2013, In : Ophthalmology. 120, 9, p. 1745-1755 11 p.

Research output: Contribution to journalArticle

Electronic Health Records
Ophthalmology
Documentation
Glaucoma
Matched-Pair Analysis
22 Citations
Electronic Health Records
Ophthalmology
Documentation
Databases
Population
2012
44 Citations

Impact of intraocular pressure on changes of blood flow in the retina, choroid, and optic nerve head in rats investigated by optical microangiography

Zhi, Z., Cepurna, W. O., Johnson, E. C., Morrison, J. C. & Wang, R. K., Sep 1 2012, In : Biomedical Optics Express. 3, 9, p. 2220-2233 14 p.

Research output: Contribution to journalArticle

intraocular pressure
Choroid
retina
Optic Disk
nerves
196 Citations

Quantitative OCT angiography of optic nerve head blood flow

Jia, Y., Morrison, J. C., Tokayer, J., Tan, O., Lombardi, L., Baumann, B., Lu, C. D., Choi, W., Fujimoto, J. G. & Huang, D., Dec 1 2012, In : Biomedical Optics Express. 3, 12, p. 3127-3137 11 p.

Research output: Contribution to journalArticle

angiography
Optic Disk
Optical Coherence Tomography
nerves
blood flow
2011
70 Citations

Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma

Johnson, E. C., Doser, T. A., Cepurna, W. O., Dyck, J. A., Jia, L., Guo, Y., Lambert, W. S. & Morrison, J. C., Jan 2011, In : Investigative Ophthalmology and Visual Science. 52, 1, p. 504-518 15 p.

Research output: Contribution to journalArticle

Optic Nerve Injuries
Optic Disk
Craniocerebral Trauma
Glaucoma
Interleukin-6
41 Citations

Early gene expression changes in the retinal ganglion cell layer of a rat glaucoma model

Guo, Y., Johnson, E. C., Cepurna, W. O., Dyck, J. A., Doser, T. & Morrison, J. C., Mar 2011, In : Investigative Ophthalmology and Visual Science. 52, 3, p. 1460-1473 14 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Glaucoma
Gene Expression
Ganglia
Genes
51 Citations

Pathophysiology of human glaucomatous optic nerve damage: Insights from rodent models of glaucoma

Morrison, J. C., Cepurna Ying Guo, W. O. & Johnson, E. C., Aug 2011, In : Experimental Eye Research. 93, 2, p. 156-164 9 p.

Research output: Contribution to journalArticle

Optic Disk
Optic Nerve
Intraocular Pressure
Glaucoma
Primates
62 Citations

Volumetric and quantitative imaging of retinal blood flow in rats with optical microangiography

Zhi, Z., Cepurna, W., Johnson, E., Shen, T., Morrison, J. & Wang, R. K., Mar 1 2011, In : Biomedical Optics Express. 2, 3, p. 579-591 13 p.

Research output: Contribution to journalArticle

angiography
blood flow
imaging techniques
rats
Angiography
2010
32 Citations

Retinal cell responses to elevated intraocular pressure: A gene array comparison between the whole retina and retinal ganglion cell layer

Guo, Y., Cepurna, W. O., Dyck, J. A., Doser, T. A., Johnson, E. C. & Morrison, J. C., Jun 2010, In : Investigative Ophthalmology and Visual Science. 51, 6, p. 3003-3018 16 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Intraocular Pressure
Retina
Genes
Laser Capture Microdissection
2009
28 Citations

Does elevated intraocular pressure reduce retinal TRKB-mediated survival signaling in experimental glaucoma?

Guo, Y., Johnson, E., Cepurna, W., Jia, L., Dyck, J. & Morrison, J. C., Dec 2009, In : Experimental Eye Research. 89, 6, p. 921-933 13 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Glaucoma
Messenger RNA
Wounds and Injuries
Retinal Ganglion Cells
82 Citations

Friend or foe? Resolving the impact of glial responses in glaucoma

Johnson, E. C. & Morrison, J. C., Jun 2009, In : Journal of Glaucoma. 18, 5, p. 341-353 13 p.

Research output: Contribution to journalArticle

Neuroglia
Glaucoma
Optic Disk
Retina
Retinal Ganglion Cells
62 Citations

Neurotrophin roles in retinal ganglion cell survival: Lessons from rat glaucoma models

Johnson, E. C., Guo, Y., Cepurna, W. O. & Morrison, J. C., Apr 30 2009, In : Experimental Eye Research. 88, 4, p. 808-815 8 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Nerve Growth Factors
Glaucoma
Cell Survival
Pressure
31 Citations

Reliability and sensitivity of the TonoLab rebound tonometer in awake Brown Norway rats

Morrison, J. C., Jia, L., Cepurna, W., Guo, Y. & Johnson, E., 2009, In : Investigative Ophthalmology and Visual Science. 50, 6, p. 2802-2808 7 p.

Research output: Contribution to journalArticle

Optic Nerve
Reading
Lighting
Transducers
Optic Nerve Injuries
2008
26 Citations

Comparison of anterior segment structures in two rat glaucoma models: An ultrasound biomicroscopic study

Nissirios, N., Chanis, R., Johnson, E., Morrison, J., Cepurna, W. O., Jia, L., Mittag, T. & Danias, J., Jun 2008, In : Investigative Ophthalmology and Visual Science. 49, 6, p. 2478-2482 5 p.

Research output: Contribution to journalArticle

Glaucoma
Veins
Anterior Chamber
Sclerosis
Cautery

Peer discussion

Morrison, J. C., Ritch, R., Flach, A. J., Minckler, D. & Bobrow, J. C., 2008, In : Transactions of the American Ophthalmological Society. 106, p. 97-99 3 p.

Research output: Contribution to journalArticle

55 Citations

Rat models for glaucoma research

Morrison, J. C., Johnson, E. & Cepurna, W. O., 2008, In : Progress in Brain Research. 173, p. 285-301 17 p.

Research output: Contribution to journalArticle

Glaucoma
Pressure
Research
Optic Disk
Optic Nerve
5 Citations

Surgical reduction of dysesthetic blebs

Lloyd, M., Giegengack, M. & Morrison, J. C., Dec 2008, In : Archives of Ophthalmology. 126, 12, p. 1759-1764 6 p.

Research output: Contribution to journalArticle

Combined Modality Therapy
Trabeculectomy
Intraocular Lens Implantation
Phacoemulsification
Paresthesia
2007
152 Citations

Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model

Johnson, E. C., Jia, L., Cepurna, W. O., Doser, T. A. & Morrison, J. C., Jul 2007, In : Investigative Ophthalmology and Visual Science. 48, 7, p. 3161-3177 17 p.

Research output: Contribution to journalArticle

Optic Disk
Intraocular Pressure
Glaucoma
Gene Expression
Wounds and Injuries