John Morrison &ndash; Publications

2019

Automated phase unwrapping in Doppler optical coherence tomography

Pi, S., Camino, A., Wei, X., Hormel, T. T., Cepurna, W., Morrison, J. & Yali, J., Jan 1 2019, In : Journal of Biomedical Optics. 24, 1, p. 1-4 4 p.

Research output: Contribution to journal › Article

Optical tomography

tomography

retina

blood flow

Phase shift

Early Optic Nerve Head Glial Proliferation and Jak-Stat Pathway Activation in Chronic Experimental Glaucoma

Lozano, D. C., Choe, T. E., Cepurna, W. O., Morrison, J. & Johnson, E., Mar 1 2019, In : Investigative ophthalmology & visual science. 60, 4, p. 921-932 12 p.

Research output: Contribution to journal › Article

Open Access

Optic Disk

Neuroglia

Glaucoma

Astrocytes

Wounds and Injuries

1 Citation (Scopus)

Evaluating changes of blood flow in retina, choroid, and outer choroid in rats in response to elevated intraocular pressure by 1300 nm swept-source OCT

Xu, J., Li, Y., Song, S., Cepurna, W., Morrison, J. & Wang, R. K., Jan 1 2019, In : Microvascular Research. 121, p. 37-45 9 p.

Research output: Contribution to journal › Article

Choroid

Intraocular Pressure

Retina

Rats

Optical tomography

Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

Pi, S., Hormel, T. T., Wei, X., Cepurna, W., Camino, A., Guo, Y., Huang, D., Morrison, J. & Yali, J., Oct 1 2019, In : Neurophotonics. 6, 4, 041104.

Research output: Contribution to journal › Article

Open Access

Optical Coherence Tomography

Intraocular Pressure

Light

Oxygen

Glaucoma

Optic nerve head astrocytes display axon-dependent and-independent reactivity in response to acutely elevated intraocular pressure

Tehrani, S., Davis, L., Cepurna, W. O., Delf, R. K., Lozano, D. C., Choe, T. E., Johnson, E. & Morrison, J., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 1, p. 312-321 10 p.

Research output: Contribution to journal › Article

Optic Nerve Injuries

Optic Disk

Intraocular Pressure

Astrocytes

Axons

Projection-Resolved Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma

Liu, L., Edmunds, L. B., Takusagawa, H., Tehrani, S., Lombardi, L., Morrison, J., Yali, J. & Huang, D., Nov 1 2019, In : American journal of ophthalmology. 207, p. 99-109 11 p.

Research output: Contribution to journal › Article

Optical Coherence Tomography

Glaucoma

Nerve Fibers

Retina

Angiography

1 Citation (Scopus)

Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

Wei, X., Camino, A., Pi, S., Hormel, T. T., Cepurna, W., Huang, D., Morrison, J. & Yali, J., Jan 1 2019, In : Optics Letters. 44, 6, p. 1431-1434 4 p.

Research output: Contribution to journal › Article

angiography

acquisition

tomography

vignetting

defocusing

2018

2 Citations (Scopus)

A Methodology for Individual-Specific Modeling of Rat Optic Nerve Head Biomechanics in Glaucoma

Schwaner, S. A., Kight, A. M., Perry, R. N., Pazos, M., Yang, H., Johnson, E., Morrison, J., Burgoyne, C. F. & Ross Ethier, C., Aug 1 2018, In : Journal of Biomechanical Engineering. 140, 8, 084501.

Research output: Contribution to journal › Article

Biomechanics

Optic Disk

Biomechanical Phenomena

Glaucoma

Rats

9 Citations (Scopus)

Automated spectroscopic retinal oximetry with visible-light optical coherence tomography

Pi, S., Camino, A., Cepurna, W., Wei, X., Zhang, M., Huang, D., Morrison, J. & Yali, J., May 1 2018, In : Biomedical Optics Express. 9, 5, p. 2056-2067 12 p., #320440.

Research output: Contribution to journal › Article

oximetry

Oximetry

Optical Coherence Tomography

tomography

Oxygen

Brinzolamide-induced Follicular Conjunctivitis

Young, J. W., Clements, J., Morrison, J. & Takusagawa, H., Jan 1 2018, (Accepted/In press) In : Journal of Glaucoma.

Research output: Contribution to journal › Article

Conjunctivitis

brinzolamide

3 Citations (Scopus)

Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT

Wei, X., Camino, A., Pi, S., Cepurna, W., Huang, D., Morrison, J. & Yali, J., May 1 2018, In : Optics Letters. 43, 9, p. 2204-2207 4 p.

Research output: Contribution to journal › Article

standard deviation

tomography

retinal images

angiography

phase shift

1 Citation (Scopus)

Hypertonic saline injection model of experimental glaucoma in rats

Morrison, J., Johnson, E. & Cepurna, W. O., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1695. p. 11-21 11 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Glaucoma

Theoretical Models

Intraocular Pressure

Injections

Rodentia

2 Citations (Scopus)

Investigation of MicroRNA expression in experimental glaucoma

Jayaram, H., Lozano, D. C., Johnson, E. & Morrison, J., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1695. p. 287-297 11 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

MicroRNAs

Glaucoma

Small Untranslated RNA

Optic Disk

Intraocular Pressure

1 Citation (Scopus)

In Vivo Small Molecule Delivery to the Optic Nerve in a Rodent Model

Tehrani, S., Delf, R. K., Cepurna, W. O., Davis, L., Johnson, E. & Morrison, J., Dec 1 2018, In : Scientific Reports. 8, 1, 4453.

Research output: Contribution to journal › Article

Optic Disk

Optic Nerve

Rodentia

Actins

Optic Nerve Diseases

4 Citations (Scopus)

Rodent retinal circulation organization and oxygen metabolism revealed by visible-light optical coherence tomography

Pi, S., Camino, A., Wei, X., Simonett, J., Cepurna, W., Huang, D., Morrison, J. & Yali, J., Nov 1 2018, In : Biomedical Optics Express. 9, 11, p. 5851-5862 12 p., #345706.

Research output: Contribution to journal › Article

oxygen metabolism

rodents

Optical Coherence Tomography

metabolism

Rodentia

7 Citations (Scopus)

The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography

Jiang, X., Johnson, E., Cepurna, W., Lozano, D., Men, S., Wang, R. K. & Morrison, J., Jan 1 2018, In : Microvascular Research. 115, p. 12-19 8 p.

Research output: Contribution to journal › Article

Angiography

Optical tomography

Optical Coherence Tomography

Intraocular Pressure

Animals

Utilizing RNA-seq to identify differentially expressed genes in glaucoma model tissues, such as the rodent optic nerve head

Lozano, D. C., Choi, D., Jayaram, H., Morrison, J. & Johnson, E., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1695. p. 299-310 12 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

RNA Sequence Analysis

Optic Disk

Intraocular Pressure

Glaucoma

Retina

2017

9 Citations (Scopus)

Angiographic and structural imaging using high axial resolution fiber-based visible-light OCT

Pi, S., Camino, A., Zhang, M., Cepurna, W., Liu, G., Huang, D., Morrison, J. & Yali, J., Oct 1 2017, In : Biomedical Optics Express. 8, 10, p. 4595-4608 14 p., #304064.

Research output: Contribution to journal › Article

retina

rats

Retina

chickens

embryos

1 Citation (Scopus)

Author response: Comparison of MicroRNA expression in aqueous humour of normal and primary open-angle glaucoma patients using PCR arrays: A pilot study

Jayaram, H., Lozano, D. C., Johnson, E., Choe, T. E., Cepurna, W. O., Saugstad, J., Morrison, J. & Keller, K., Oct 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 12, 1 p.

Research output: Contribution to journal › Letter

Aqueous Humor

MicroRNAs

Polymerase Chain Reaction

Primary Open Angle Glaucoma

3 Citations (Scopus)

Automated boundary detection of the optic disc and layer segmentation of the peripapillary retina in volumetric structural and angiographic optical coherence tomography

Zang, P., Gao, S. S., Hwang, T., Flaxel, C., Wilson, D., Morrison, J., Huang, D., Li, D. & Yali, J., Mar 1 2017, In : Biomedical Optics Express. 8, 3, p. 1306-1318 13 p., #282471.

Research output: Contribution to journal › Article

retina

edge detection

Optic Disk

Optical Coherence Tomography

Retina

18 Citations (Scopus)

Biological aspects of axonal damage in glaucoma: A brief review

Tamm, E. R., Ethier, C. R., Dowling, J. E., Downs, C., Ellisman, M. H., Fisher, S., Fortune, B., Fruttiger, M., Jakobs, T., Lewis, G., Mitchell, C. H., Morrison, J., Morrison, J., Sigal, I., Sofroniew, M., Wang, L., Wiggs, J., Wu, S. & Masland, R. H., Jan 22 2017, (Accepted/In press) In : Experimental Eye Research.

Research output: Contribution to journal › Article

Optic Disk

Glaucoma

Intraocular Pressure

Sclera

Astrocytes

15 Citations (Scopus)

Biomechanical aspects of axonal damage in glaucoma: A brief review

The Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration Participants, Apr 1 2017, In : Experimental Eye Research. 157, p. 13-19 7 p.

Research output: Contribution to journal › Review article

Optic Disk

Glaucoma

Intraocular Pressure

Biomechanical Phenomena

Astrocytes

9 Citations (Scopus)

Comparison of microRNA expression in aqueous humor of normal and primary open-angle glaucoma patients using PCR arrays: A pilot study

Jayaram, H., Phillips, J. I., Lozano, D. C., Choe, T. E., Cepurna, W. O., Johnson, E., Morrison, J., Gattey, D. M., Saugstad, J. & Keller, K., Jun 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 7, p. 2884-2890 7 p.

Research output: Contribution to journal › Article

Aqueous Humor

MicroRNAs

Polymerase Chain Reaction

Primary Open Angle Glaucoma

Encyclopedias

44 Citations (Scopus)

Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma

Takusagawa, H., Liu, L., Ma, K. N., Yali, J., Gao, S. S., Zhang, M., Edmunds, L. B., Parikh, M., Tehrani, S., Morrison, J. & Huang, D., 2017, (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journal › Article

Optical Coherence Tomography

Glaucoma

Blood Vessels

Angiography

Visual Fields

2016

11 Citations (Scopus)

A period of controlled elevation of IOP (CEI) produces the specific gene expression responses and focal injury pattern of experimental rat glaucoma

Morrison, J., Cepurna, W. O., Tehrani, S., Choe, T. E., Jayaram, H., Lozano, D. C., Fortune, B. & Johnson, E., Dec 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 15, p. 6700-6711 12 p.

Research output: Contribution to journal › Article

Optic Disk

Glaucoma

Gene Expression

Optic Nerve

Wounds and Injuries

12 Citations (Scopus)

Astrocyte structural and molecular response to elevated intraocular pressure occurs rapidly and precedes axonal tubulin rearrangement within the optic nerve head in a rat model

Tehrani, S., Davis, L., Cepurna, W. O., Choe, T. E., Lozano, D. C., Monfared, A., Cooper, L., Cheng, J., Johnson, E. & Morrison, J., Nov 1 2016, In : PLoS One. 11, 11, e0167364.

Research output: Contribution to journal › Article

astrocytes

Optic Disk

Tubulin

optics

tubulin

24 Citations (Scopus)

Compensation for reflectance variation in vessel density quantification by optical coherence tomography angiography

Gao, S. S., Yali, J., Liu, L., Zhang, M., Takusagawa, H., Morrison, J. & Huang, D., Aug 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4485-4492 8 p.

Research output: Contribution to journal › Article

Optical Coherence Tomography

Angiography

Noise

Optic Disk

Blood Vessels

10 Citations (Scopus)

Expansions of the neurovascular scleral canal and contained optic nerve occur early in the hypertonic saline rat experimental glaucoma model

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E., Morrison, J. & Burgoyne, C. F., Apr 1 2016, In : Experimental Eye Research. 145, p. 173-186 14 p.

Research output: Contribution to journal › Article

Optic Nerve

Glaucoma

Theoretical Models

Optic Disk

Nerve Expansion

17 Citations (Scopus)

Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism

Teotia, P., Chopra, D. A., Dravid, S. M., Van Hook, M. J., Qiu, F., Morrison, J., Rizzino, A. & Ahmad, I., 2016, (Accepted/In press) In : Stem Cells.

Research output: Contribution to journal › Article

Pluripotent Stem Cells

Retinal Ganglion Cells

Stem Cells

Induced Pluripotent Stem Cells

Embryonic Stem Cells

3 Citations (Scopus)

Glaucoma increases retinal surface contour variability as measured by optical coherence tomography

Tan, O., Liu, L., Zhang, X., Morrison, J. & Huang, D., 2016, In : Investigative Ophthalmology and Visual Science. 57, 9, p. OCT438-OCT443

Research output: Contribution to journal › Article

Optical Coherence Tomography

Glaucoma

Nerve Fibers

Visual Field Tests

Optic Disk

Optic nerve: Atypical nerves and nerve findings

Edmunds, L. B. & Morrison, J., Jan 1 2016, Pearls of Glaucoma Management: Second Edition. Springer Berlin Heidelberg, p. 71-83 13 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Optics

2015

7 Citations (Scopus)

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy

Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I., Jun 1 2015, In : Stem Cells. 33, 6, p. 1743-1758 16 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Induced Pluripotent Stem Cells

Glaucoma

Ocular Hypertension

Acids

18 Citations (Scopus)

Evaluation of the effect of elevated intraocular pressure and reduced ocular perfusion pressure on retinal capillary bed filling and total retinal blood flow in rats by OMAG/OCT

Zhi, Z., Cepurna, W., Johnson, E., Jayaram, H., Morrison, J. & Wang, R. K., Sep 1 2015, In : Microvascular Research. 101, p. 86-95 10 p.

Research output: Contribution to journal › Article

Optical tomography

Optical Coherence Tomography

Intraocular Pressure

Rats

Blood

18 Citations (Scopus)

Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene

Ying, H. H., Turturro, S. S., Nguyen, T. T., Shen, X. X., Zelkha, R. R., Johnson, E., Morrison, J. & Yue, B. B. Y. J. T., May 6 2015, In : BMC Cell Biology. 16, 1, 14.

Research output: Contribution to journal › Article

Autophagy

Proteasome Endopeptidase Complex

Ubiquitin

Retinal Ganglion Cells

Fluorescence

2 Citations (Scopus)

Introduction to special issue on glaucomatous optic neuropathy: In vivo models and techniques

Ethier, C. R., Morrison, J. & Clark, A. F., Jul 20 2015, In : Experimental Eye Research. 141, p. 1-2 2 p.

Research output: Contribution to journal › Article

Animal Disease Models

Optic Nerve Diseases

Optic Nerve

Intraocular Pressure

Glaucoma

13 Citations (Scopus)

MicroRNA expression in the glaucomatous retina

Jayaram, H., Cepurna, W. O., Johnson, E. & Morrison, J., Dec 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 13, p. 7971-7982 12 p.

Research output: Contribution to journal › Article

MicroRNAs

Retina

Intraocular Pressure

Central Nervous System

Chemical Databases

19 Citations (Scopus)

Modeling glaucoma in rats by sclerosing aqueous outflow pathways to elevate intraocular pressure

Morrison, J., Cepurna, W. O. & Johnson, E., Mar 28 2015, In : Experimental Eye Research. 141, p. 23-32 10 p.

Research output: Contribution to journal › Article

Intraocular Pressure

Glaucoma

Aqueous Humor

Optic Disk

Injections

255 Citations (Scopus)

Optical coherence tomography angiography of the peripapillary retina in glaucoma

Liu, L., Yali, J., Takusagawa, H., Pechauer, A. D., Edmunds, L. B., Lombardi, L., Davis, E., Morrison, J. & Huang, D., Sep 1 2015, In : JAMA Ophthalmology. 133, 9, p. 1045-1052 8 p.

Research output: Contribution to journal › Article

Optical Coherence Tomography

Glaucoma

Retina

Angiography

Perfusion

25 Citations (Scopus)

Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye

Lu, W., Hu, H., Sévigny, J., Gabelt, B. T., Kaufman, P. L., Johnson, E., Morrison, J., Zode, G. S., Sheffield, V. C., Zhang, X., Laties, A. M. & Mitchell, C. H., 2015, In : Investigative Ophthalmology and Visual Science. 56, 5, p. 3075-3083 9 p.

Research output: Contribution to journal › Article

Glaucoma

Primates

Adenosine Triphosphate

Astrocytes

Retinal Neurons

12 Citations (Scopus)

Rat optic nerve head anatomy within 3D histomorphometric reconstructions of normal control eyes

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E., Morrison, J. & Burgoyne, C. F., Oct 1 2015, In : Experimental Eye Research. 139, p. 1-12 12 p.

Research output: Contribution to journal › Article

Bruch Membrane

Optic Disk

Anatomy

Retinal Vein

Sclera

2014

23 Citations (Scopus)

An acute intraocular pressure challenge to assess retinal ganglion cell injury and recovery in the mouse

Crowston, J. G., Kong, Y. X. G., Trounce, I. A., Dang, T. M., Fahy, E. T., Bui, B. V., Morrison, J. & Chrysostomou, V., Dec 12 2014, In : Experimental Eye Research. 141, p. 3-8 6 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Intraocular Pressure

Wounds and Injuries

Neuroglia

Glaucoma

19 Citations (Scopus)

Astrocyte processes label for filamentous actin and reorient early within the optic nerve head in a rat glaucoma model

Tehrani, S., Johnson, E., Cepurna, W. O. & Morrison, J., Oct 1 2014, In : Investigative Ophthalmology and Visual Science. 55, 10, p. 6945-6952 8 p.

Research output: Contribution to journal › Article

Optic Disk

Astrocytes

Glaucoma

Actins

Optic Nerve

344 Citations (Scopus)

Optical coherence tomography angiography of optic disc perfusion in glaucoma

Yali, J., Wei, E., Wang, X., Zhang, X., Morrison, J., Parikh, M., Lombardi, L., Gattey, D. M., Armour, R. L., Edmunds, L. B., Kraus, M. F., Fujimoto, J. G. & Huang, D., 2014, In : Ophthalmology. 121, 7, p. 1322-1332 11 p.

Research output: Contribution to journal › Article

Optic Disk

Optical Coherence Tomography

Glaucoma

Angiography

Perfusion

12 Citations (Scopus)

Radiation pretreatment does not protect the rat optic nerve from elevated intraocular pressure–induced injury

Johnson, E., Cepurna, W. O., Choi, D., Choe, T. E. & Morrison, J., Dec 7 2014, In : Investigative Ophthalmology and Visual Science. 56, 1, p. 412-419 8 p.

Research output: Contribution to journal › Article

Optic Nerve

Intraocular Pressure

Radiation

Wounds and Injuries

Glaucoma

2013

16 Citations (Scopus)

Electronic health record systems in ophthalmology: Impact on clinical documentation

Sanders, D. S., Lattin, D. J., Read-Brown, S., Tu, D., Wilson, D., Hwang, T., Morrison, J., Yackel, T. & Chiang, M., Sep 2013, In : Ophthalmology. 120, 9, p. 1745-1755 11 p.

Research output: Contribution to journal › Article

Electronic Health Records

Ophthalmology

Documentation

Glaucoma

Matched-Pair Analysis

29 Citations (Scopus)

Evaluation of electronic health record implementation in ophthalmology at an academic medical center (An American Ophthalmological Society Thesis)

Chiang, M., Read-Brown, S., Tu, D., Choi, D., Sanders, D. S., Hwang, T., Bailey, S., Karr, D., Cottle, E., Morrison, J., Wilson, D. & Yackel, T., 2013, In : Transactions of the American Ophthalmological Society. 111, p. 70-92 23 p.

Research output: Contribution to journal › Article

Electronic Health Records

Ophthalmology

Documentation

Databases

Population

2012

50 Citations (Scopus)

Impact of intraocular pressure on changes of blood flow in the retina, choroid, and optic nerve head in rats investigated by optical microangiography

Zhi, Z., Cepurna, W. O., Johnson, E., Morrison, J. & Wang, R. K., Sep 1 2012, In : Biomedical Optics Express. 3, 9, p. 2220-2233 14 p.

Research output: Contribution to journal › Article

intraocular pressure

Choroid

retina

Optic Disk

nerves

230 Citations (Scopus)

Quantitative OCT angiography of optic nerve head blood flow

Yali, J., Morrison, J., Tokayer, J., Tan, O., Lombardi, L., Baumann, B., Lu, C. D., Choi, W., Fujimoto, J. G. & Huang, D., Dec 1 2012, In : Biomedical Optics Express. 3, 12, p. 3127-3137 11 p.

Research output: Contribution to journal › Article

angiography

Optic Disk

Optical Coherence Tomography

nerves

blood flow

2011

73 Citations (Scopus)

Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma

Johnson, E., Doser, T. A., Cepurna, W. O., Dyck, J. A., Jia, L., Guo, Y., Lambert, W. S. & Morrison, J., Jan 2011, In : Investigative Ophthalmology and Visual Science. 52, 1, p. 504-518 15 p.

Research output: Contribution to journal › Article

Optic Nerve Injuries

Optic Disk

Craniocerebral Trauma

Glaucoma

Interleukin-6

44 Citations (Scopus)

Early gene expression changes in the retinal ganglion cell layer of a rat glaucoma model

Guo, Y., Johnson, E., Cepurna, W. O., Dyck, J. A., Doser, T. & Morrison, J., Mar 2011, In : Investigative Ophthalmology and Visual Science. 52, 3, p. 1460-1473 14 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Glaucoma

Gene Expression

Ganglia

Genes