John Morrison

Professor

  • 5176 Citations
  • 41 h-Index
1982 …2020
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Research Output 1982 2018

  • 5176 Citations
  • 41 h-Index
  • 109 Article
  • 5 Chapter
  • 1 Letter
  • 1 Review article
2018

Automated spectroscopic retinal oximetry with visible-light optical coherence tomography

Pi, S., Camino, A., Cepurna, W., Wei, X., Zhang, M., Huang, D., Morrison, J. & Jia, Y. May 1 2018 In : Biomedical Optics Express. 9, 5, p. 2056-2067 12 p., #320440

Research output: Contribution to journalArticle

oximetry
Oximetry
Optical tomography
Optical Coherence Tomography
tomography

Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT

Wei, X., Camino, A., Pi, S., Cepurna, W., Huang, D., Morrison, J. C. & Jia, Y. May 1 2018 In : Optics Letters. 43, 9, p. 2204-2207 4 p.

Research output: Contribution to journalArticle

Motion compensation
Optical tomography
standard deviation
tomography
retinal images

Hypertonic saline injection model of experimental glaucoma in rats

Morrison, J. C., Johnson, E. C. & Cepurna, W. O. Jan 1 2018 Methods in Molecular Biology. Humana Press Inc., Vol. 1695, p. 11-21 11 p. (Methods in Molecular Biology; vol. 1695)

Research output: Chapter in Book/Report/Conference proceedingChapter

Aqueous Humor
Optic Nerve
Intraocular Pressure
Glaucoma
Theoretical Models
1 Citations

Investigation of MicroRNA expression in experimental glaucoma

Jayaram, H., Lozano, D. C., Johnson, E. C. & Morrison, J. C. Jan 1 2018 Methods in Molecular Biology. Humana Press Inc., Vol. 1695, p. 287-297 11 p. (Methods in Molecular Biology; vol. 1695)

Research output: Chapter in Book/Report/Conference proceedingChapter

Optic Disk
MicroRNAs
Glaucoma
Gene Expression
Polymerase Chain Reaction

In Vivo Small Molecule Delivery to the Optic Nerve in a Rodent Model

Tehrani, S., Delf, R. K., Cepurna, W. O., Davis, L., Johnson, E. C. & Morrison, J. C. Dec 1 2018 In : Scientific Reports. 8, 1, 4453

Research output: Contribution to journalArticle

Optic Disk
Optic Nerve
Rodentia
Actins
Optic Nerve Diseases
1 Citations

The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography

Jiang, X., Johnson, E., Cepurna, W., Lozano, D., Men, S., Wang, R. K. & Morrison, J. Jan 1 2018 In : Microvascular Research. 115, p. 12-19 8 p.

Research output: Contribution to journalArticle

Angiography
Optical tomography
Optical Coherence Tomography
Intraocular Pressure
Animals

Utilizing RNA-seq to identify differentially expressed genes in glaucoma model tissues, such as the rodent optic nerve head

Lozano, D. C., Choi, D., Jayaram, H., Morrison, J. C. & Johnson, E. C. Jan 1 2018 Methods in Molecular Biology. Humana Press Inc., Vol. 1695, p. 299-310 12 p. (Methods in Molecular Biology; vol. 1695)

Research output: Chapter in Book/Report/Conference proceedingChapter

RNA Sequence Analysis
Optic Disk
Intraocular Pressure
Glaucoma
Retina
2017
4 Citations

Angiographic and structural imaging using high axial resolution fiber-based visible-light OCT

Pi, S., Camino, A., Zhang, M., Cepurna, W., Liu, G., Huang, D., Morrison, J. & Jia, Y. Oct 1 2017 In : Biomedical Optics Express. 8, 10, p. 4595-4608 14 p., #304064

Research output: Contribution to journalArticle

retina
rats
Retina
chickens
embryos
Aqueous Humor
MicroRNAs
Polymerase Chain Reaction
Primary Open Angle Glaucoma
2 Citations
retina
edge detection
Optic Disk
Optical Coherence Tomography
Retina
7 Citations

Biological aspects of axonal damage in glaucoma: A brief review

Tamm, E. R., Ethier, C. R., Dowling, J. E., Downs, C., Ellisman, M. H., Fisher, S., Fortune, B., Fruttiger, M., Jakobs, T., Lewis, G., Mitchell, C. H., Morrison, J., Sharma, S. C., Sigal, I., Sofroniew, M., Wang, L., Wiggs, J., Wu, S. & Masland, R. H. Jan 22 2017 (Accepted/In press) In : Experimental Eye Research.

Research output: Contribution to journalArticle

Optic Disk
Glaucoma
Intraocular Pressure
Sclera
Astrocytes
7 Citations

Biomechanical aspects of axonal damage in glaucoma: A brief review

Stowell, C. , Burgoyne, C. F. , Tamm, E. R. , Ethier, C. R. , Dowling, J. E. , Downs, C. , Ellisman, M. H. , Fisher, S. , Fortune, B. , Fruttiger, M. , Jakobs, T. , Lewis, G. , Masland, R. H. , Mitchell, C. H. , Morrison, J. , Sharma, S. C. , Sigal, I. , Sofroniew, M. , Wang, L. , Wiggs, J. & 2 others Wu, S. & The Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration Participants Apr 1 2017 In : Experimental Eye Research. 157, p. 13-19 7 p.

Research output: Contribution to journalReview article

Optic Disk
Glaucoma
Intraocular Pressure
Biomechanical Phenomena
Astrocytes
5 Citations

Comparison of microRNA expression in aqueous humor of normal and primary open-angle glaucoma patients using PCR arrays: A pilot study

Jayaram, H., Phillips, J. I., Lozano, D. C., Choe, T. E., Cepurna, W. O., Johnson, E. C., Morrison, J. C., Gattey, D. M., Saugstad, J. A. & Keller, K. E. Jun 1 2017 In : Investigative Ophthalmology and Visual Science. 58, 7, p. 2884-2890 7 p.

Research output: Contribution to journalArticle

Aqueous Humor
MicroRNAs
Polymerase Chain Reaction
Primary Open Angle Glaucoma
Encyclopedias
9 Citations

Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma

Takusagawa, H. L., Liu, L., Ma, K. N., Jia, Y., Gao, S. S., Zhang, M., Edmunds, B., Parikh, M., Tehrani, S., Morrison, J. C. & Huang, D. 2017 (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Glaucoma
Blood Vessels
Angiography
Visual Fields
2016
5 Citations

A period of controlled elevation of IOP (CEI) produces the specific gene expression responses and focal injury pattern of experimental rat glaucoma

Morrison, J. C., Cepurna, W. O., Tehrani, S., Choe, T. E., Jayaram, H., Lozano, D. C., Fortune, B. & Johnson, E. C. Dec 1 2016 In : Investigative Ophthalmology and Visual Science. 57, 15, p. 6700-6711 12 p.

Research output: Contribution to journalArticle

Optic Disk
Glaucoma
Gene Expression
Optic Nerve
Wounds and Injuries
4 Citations

Astrocyte structural and molecular response to elevated intraocular pressure occurs rapidly and precedes axonal tubulin rearrangement within the optic nerve head in a rat model

Tehrani, S., Davis, L., Cepurna, W. O., Choe, T. E., Lozano, D. C., Monfared, A., Cooper, L., Cheng, J., Johnson, E. C. & Morrison, J. C. Nov 1 2016 In : PLoS One. 11, 11, e0167364

Research output: Contribution to journalArticle

astrocytes
Optic Disk
Tubulin
optics
tubulin
10 Citations

Compensation for reflectance variation in vessel density quantification by optical coherence tomography angiography

Gao, S. S., Jia, Y., Liu, L., Zhang, M., Takusagawa, H. L., Morrison, J. C. & Huang, D. Aug 1 2016 In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4485-4492 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Angiography
Noise
Optic Disk
Blood Vessels
7 Citations

Expansions of the neurovascular scleral canal and contained optic nerve occur early in the hypertonic saline rat experimental glaucoma model

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E. C., Morrison, J. C. & Burgoyne, C. F. Apr 1 2016 In : Experimental Eye Research. 145, p. 173-186 14 p.

Research output: Contribution to journalArticle

Optic Nerve
Glaucoma
Theoretical Models
Optic Disk
Nerve Expansion
9 Citations

Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism

Teotia, P., Chopra, D. A., Dravid, S. M., Van Hook, M. J., Qiu, F., Morrison, J., Rizzino, A. & Ahmad, I. 2016 (Accepted/In press) In : Stem Cells.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Retinal Ganglion Cells
Stem Cells
Induced Pluripotent Stem Cells
Embryonic Stem Cells
2 Citations
Optical Coherence Tomography
Glaucoma
Nerve Fibers
Visual Field Tests
Optic Disk

Optic nerve: Atypical nerves and nerve findings

Edmunds, B. & Morrison, J. C. Jan 1 2016 Pearls of Glaucoma Management: Second Edition. Springer Berlin Heidelberg, p. 71-83 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Optics
2015
3 Citations

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy

Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I. Jun 1 2015 In : Stem Cells. 33, 6, p. 1743-1758 16 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Induced Pluripotent Stem Cells
Glaucoma
Ocular Hypertension
Acids
11 Citations
Optical tomography
Optical Coherence Tomography
Intraocular Pressure
Rats
Blood
13 Citations

Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene

Ying, H. H., Turturro, S. S., Nguyen, T. T., Shen, X. X., Zelkha, R. R., Johnson, E. E. C., Morrison, J. J. C. & Yue, B. B. Y. J. T. May 6 2015 In : BMC Cell Biology. 16, 1, 14

Research output: Contribution to journalArticle

Autophagy
Proteasome Endopeptidase Complex
Ubiquitin
Retinal Ganglion Cells
Fluorescence
2 Citations

Introduction to special issue on glaucomatous optic neuropathy: In vivo models and techniques

Ethier, C. R., Morrison, J. C. & Clark, A. F. Jul 20 2015 In : Experimental Eye Research. 141, p. 1-2 2 p.

Research output: Contribution to journalArticle

Animal Disease Models
Optic Nerve Diseases
Optic Nerve
Intraocular Pressure
Glaucoma
12 Citations

MicroRNA expression in the glaucomatous retina

Jayaram, H., Cepurna, W. O., Johnson, E. C. & Morrison, J. C. Dec 1 2015 In : Investigative Ophthalmology and Visual Science. 56, 13, p. 7971-7982 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Retina
Intraocular Pressure
Central Nervous System
Chemical Databases
15 Citations

Modeling glaucoma in rats by sclerosing aqueous outflow pathways to elevate intraocular pressure

Morrison, J. C., Cepurna, W. O. & Johnson, E. C. Mar 28 2015 In : Experimental Eye Research. 141, p. 23-32 10 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Glaucoma
Aqueous Humor
Optic Disk
Injections
177 Citations

Optical coherence tomography angiography of the peripapillary retina in glaucoma

Liu, L., Jia, Y., Takusagawa, H. L., Pechauer, A. D., Edmunds, B., Lombardi, L., Davis, E., Morrison, J. C. & Huang, D. Sep 1 2015 In : JAMA Ophthalmology. 133, 9, p. 1045-1052 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Glaucoma
Retina
Angiography
Perfusion
15 Citations

Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye

Lu, W., Hu, H., Sévigny, J., Gabelt, B. T., Kaufman, P. L., Johnson, E. C., Morrison, J. C., Zode, G. S., Sheffield, V. C., Zhang, X., Laties, A. M. & Mitchell, C. H. 2015 In : Investigative Ophthalmology and Visual Science. 56, 5, p. 3075-3083 9 p.

Research output: Contribution to journalArticle

Glaucoma
Primates
Adenosine Triphosphate
Astrocytes
Retinal Neurons
9 Citations

Rat optic nerve head anatomy within 3D histomorphometric reconstructions of normal control eyes

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E. C., Morrison, J. C. & Burgoyne, C. F. Oct 1 2015 In : Experimental Eye Research. 139, p. 1-12 12 p.

Research output: Contribution to journalArticle

Bruch Membrane
Optic Disk
Anatomy
Retinal Vein
Sclera
2014
19 Citations

An acute intraocular pressure challenge to assess retinal ganglion cell injury and recovery in the mouse

Crowston, J. G., Kong, Y. X. G., Trounce, I. A., Dang, T. M., Fahy, E. T., Bui, B. V., Morrison, J. C. & Chrysostomou, V. Dec 12 2014 In : Experimental Eye Research. 141, p. 3-8 6 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Intraocular Pressure
Wounds and Injuries
Neuroglia
Glaucoma
14 Citations
Optic Disk
Astrocytes
Glaucoma
Actins
Optic Nerve
259 Citations

Optical coherence tomography angiography of optic disc perfusion in glaucoma

Jia, Y., Wei, E., Wang, X., Zhang, X., Morrison, J. C., Parikh, M., Lombardi, L. H., Gattey, D. M., Armour, R. L., Edmunds, B., Kraus, M. F., Fujimoto, J. G. & Huang, D. 2014 In : Ophthalmology. 121, 7, p. 1322-1332 11 p.

Research output: Contribution to journalArticle

Optic Disk
Optical Coherence Tomography
Glaucoma
Angiography
Perfusion
10 Citations
Optic Nerve
Intraocular Pressure
Radiation
Wounds and Injuries
Glaucoma
2013
14 Citations

Electronic health record systems in ophthalmology: Impact on clinical documentation

Sanders, D. S., Lattin, D. J., Read-Brown, S., Tu, D. C., Wilson, D. J., Hwang, T. S., Morrison, J. C., Yackel, T. R. & Chiang, M. F. Sep 2013 In : Ophthalmology. 120, 9, p. 1745-1755 11 p.

Research output: Contribution to journalArticle

Electronic Health Records
Ophthalmology
Documentation
Glaucoma
Matched-Pair Analysis
16 Citations
Electronic Health Records
Ophthalmology
Documentation
Databases
Population
2012
39 Citations
intraocular pressure
Choroid
retina
Optic Disk
nerves
175 Citations

Quantitative OCT angiography of optic nerve head blood flow

Jia, Y., Morrison, J. C., Tokayer, J., Tan, O., Lombardi, L., Baumann, B., Lu, C. D., Choi, W., Fujimoto, J. G. & Huang, D. Dec 1 2012 In : Biomedical Optics Express. 3, 12, p. 3127-3137 11 p.

Research output: Contribution to journalArticle

angiography
Optic Disk
Optical Coherence Tomography
nerves
blood flow
2011
69 Citations

Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma

Johnson, E. C., Doser, T. A., Cepurna, W. O., Dyck, J. A., Jia, L., Guo, Y., Lambert, W. S. & Morrison, J. C. Jan 2011 In : Investigative Ophthalmology and Visual Science. 52, 1, p. 504-518 15 p.

Research output: Contribution to journalArticle

Optic Nerve Injuries
Optic Disk
Craniocerebral Trauma
Glaucoma
Interleukin-6
41 Citations

Early gene expression changes in the retinal ganglion cell layer of a rat glaucoma model

Guo, Y., Johnson, E. C., Cepurna, W. O., Dyck, J. A., Doser, T. & Morrison, J. C. Mar 2011 In : Investigative Ophthalmology and Visual Science. 52, 3, p. 1460-1473 14 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Glaucoma
Gene Expression
Ganglia
Genes
50 Citations

Pathophysiology of human glaucomatous optic nerve damage: Insights from rodent models of glaucoma

Morrison, J. C., Cepurna Ying Guo, W. O. & Johnson, E. C. Aug 2011 In : Experimental Eye Research. 93, 2, p. 156-164 9 p.

Research output: Contribution to journalArticle

Optic Disk
Optic Nerve
Intraocular Pressure
Glaucoma
Primates
58 Citations

Volumetric and quantitative imaging of retinal blood flow in rats with optical microangiography

Zhi, Z., Cepurna, W., Johnson, E., Shen, T., Morrison, J. & Wang, R. K. Mar 1 2011 In : Biomedical Optics Express. 2, 3, p. 579-591 13 p.

Research output: Contribution to journalArticle

angiography
blood flow
imaging techniques
rats
Angiography
2010

Optic nerve: Atypical nerves and nerve findings

Edmunds, B. & Morrison, J. C. 2010 Pearls of Glaucoma Management. Springer Berlin Heidelberg, p. 63-73 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Optic Disk
Optic Nerve
Glaucoma
Atrophy
Optic Nerve Diseases
32 Citations

Retinal cell responses to elevated intraocular pressure: A gene array comparison between the whole retina and retinal ganglion cell layer

Guo, Y., Cepurna, W. O., Dyck, J. A., Doser, T. A., Johnson, E. C. & Morrison, J. C. Jun 2010 In : Investigative Ophthalmology and Visual Science. 51, 6, p. 3003-3018 16 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Intraocular Pressure
Retina
Genes
Laser Capture Microdissection
2009
28 Citations

Does elevated intraocular pressure reduce retinal TRKB-mediated survival signaling in experimental glaucoma?

Guo, Y., Johnson, E., Cepurna, W., Jia, L., Dyck, J. & Morrison, J. C. Dec 2009 In : Experimental Eye Research. 89, 6, p. 921-933 13 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Glaucoma
Messenger RNA
Wounds and Injuries
Retinal Ganglion Cells
77 Citations

Friend or foe? Resolving the impact of glial responses in glaucoma

Johnson, E. C. & Morrison, J. C. Jun 2009 In : Journal of Glaucoma. 18, 5, p. 341-353 13 p.

Research output: Contribution to journalArticle

Neuroglia
Glaucoma
Optic Disk
Retina
Retinal Ganglion Cells
60 Citations

Neurotrophin roles in retinal ganglion cell survival: Lessons from rat glaucoma models

Johnson, E. C., Guo, Y., Cepurna, W. O. & Morrison, J. C. Apr 30 2009 In : Experimental Eye Research. 88, 4, p. 808-815 8 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Nerve Growth Factors
Glaucoma
Cell Survival
Pressure
29 Citations

Reliability and sensitivity of the TonoLab rebound tonometer in awake Brown Norway rats

Morrison, J. C., Jia, L., Cepurna, W., Guo, Y. & Johnson, E. 2009 In : Investigative Ophthalmology and Visual Science. 50, 6, p. 2802-2808 7 p.

Research output: Contribution to journalArticle

Optic Nerve
Reading
Lighting
Transducers
Optic Nerve Injuries
2008
25 Citations

Comparison of anterior segment structures in two rat glaucoma models: An ultrasound biomicroscopic study

Nissirios, N., Chanis, R., Johnson, E., Morrison, J., Cepurna, W. O., Jia, L., Mittag, T. & Danias, J. Jun 2008 In : Investigative Ophthalmology and Visual Science. 49, 6, p. 2478-2482 5 p.

Research output: Contribution to journalArticle

Glaucoma
Veins
Anterior Chamber
Sclerosis
Cautery

Peer discussion

Morrison, J. C., Ritch, R., Flach, A. J., Minckler, D. & Bobrow, J. C. 2008 In : Transactions of the American Ophthalmological Society. 106, p. 97-99 3 p.

Research output: Contribution to journalArticle