John Morrison

Professor

  • 5778 Citations
  • 43 h-Index
1982 …2020
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Research Output 1982 2019

  • 5778 Citations
  • 43 h-Index
  • 119 Article
  • 5 Chapter
  • 1 Letter
  • 1 Review article
2019
1 Citation (Scopus)

Automated phase unwrapping in Doppler optical coherence tomography

Pi, S., Camino, A., Wei, X., Hormel, T. T., Cepurna, W., Morrison, J. & Yali, J., Jan 1 2019, In : Journal of Biomedical Optics. 24, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

Optical tomography
tomography
retina
blood flow
Phase shift

Early Optic Nerve Head Glial Proliferation and Jak-Stat Pathway Activation in Chronic Experimental Glaucoma

Lozano, D. C., Choe, T. E., Cepurna, W. O., Morrison, J. & Johnson, E., Mar 1 2019, In : Investigative ophthalmology & visual science. 60, 4, p. 921-932 12 p.

Research output: Contribution to journalArticle

Open Access
Optic Disk
Neuroglia
Glaucoma
Astrocytes
Wounds and Injuries
1 Citation (Scopus)

Evaluating changes of blood flow in retina, choroid, and outer choroid in rats in response to elevated intraocular pressure by 1300 nm swept-source OCT

Xu, J., Li, Y., Song, S., Cepurna, W., Morrison, J. & Wang, R. K., Jan 1 2019, In : Microvascular Research. 121, p. 37-45 9 p.

Research output: Contribution to journalArticle

Choroid
Intraocular Pressure
Retina
Rats
Optical tomography

Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

Pi, S., Hormel, T. T., Wei, X., Cepurna, W., Camino, A., Guo, Y., Huang, D., Morrison, J. & Yali, J., Oct 1 2019, In : Neurophotonics. 6, 4, 041104.

Research output: Contribution to journalArticle

Open Access
Optical Coherence Tomography
Intraocular Pressure
Light
Oxygen
Glaucoma

Optic nerve head astrocytes display axon-dependent and-independent reactivity in response to acutely elevated intraocular pressure

Tehrani, S., Davis, L., Cepurna, W. O., Delf, R. K., Lozano, D. C., Choe, T. E., Johnson, E. & Morrison, J., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 1, p. 312-321 10 p.

Research output: Contribution to journalArticle

Optic Nerve Injuries
Optic Disk
Intraocular Pressure
Astrocytes
Axons
Optical Coherence Tomography
Glaucoma
Nerve Fibers
Retina
Angiography
1 Citation (Scopus)

Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

Wei, X., Camino, A., Pi, S., Hormel, T. T., Cepurna, W., Huang, D., Morrison, J. & Yali, J., Jan 1 2019, In : Optics Letters. 44, 6, p. 1431-1434 4 p.

Research output: Contribution to journalArticle

angiography
acquisition
tomography
vignetting
defocusing
2018
2 Citations (Scopus)

A Methodology for Individual-Specific Modeling of Rat Optic Nerve Head Biomechanics in Glaucoma

Schwaner, S. A., Kight, A. M., Perry, R. N., Pazos, M., Yang, H., Johnson, E., Morrison, J., Burgoyne, C. F. & Ross Ethier, C., Aug 1 2018, In : Journal of Biomechanical Engineering. 140, 8, 084501.

Research output: Contribution to journalArticle

Biomechanics
Optic Disk
Biomechanical Phenomena
Glaucoma
Rats
9 Citations (Scopus)

Automated spectroscopic retinal oximetry with visible-light optical coherence tomography

Pi, S., Camino, A., Cepurna, W., Wei, X., Zhang, M., Huang, D., Morrison, J. & Yali, J., May 1 2018, In : Biomedical Optics Express. 9, 5, p. 2056-2067 12 p., #320440.

Research output: Contribution to journalArticle

oximetry
Oximetry
Optical Coherence Tomography
tomography
Oxygen

Brinzolamide-induced Follicular Conjunctivitis

Young, J. W., Clements, J., Morrison, J. & Takusagawa, H., Jan 1 2018, (Accepted/In press) In : Journal of Glaucoma.

Research output: Contribution to journalArticle

Conjunctivitis
brinzolamide
3 Citations (Scopus)

Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT

Wei, X., Camino, A., Pi, S., Cepurna, W., Huang, D., Morrison, J. & Yali, J., May 1 2018, In : Optics Letters. 43, 9, p. 2204-2207 4 p.

Research output: Contribution to journalArticle

standard deviation
tomography
retinal images
angiography
phase shift
1 Citation (Scopus)

Hypertonic saline injection model of experimental glaucoma in rats

Morrison, J., Johnson, E. & Cepurna, W. O., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1695. p. 11-21 11 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceedingChapter

Glaucoma
Theoretical Models
Intraocular Pressure
Injections
Rodentia
2 Citations (Scopus)

Investigation of MicroRNA expression in experimental glaucoma

Jayaram, H., Lozano, D. C., Johnson, E. & Morrison, J., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1695. p. 287-297 11 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceedingChapter

MicroRNAs
Glaucoma
Small Untranslated RNA
Optic Disk
Intraocular Pressure
1 Citation (Scopus)

In Vivo Small Molecule Delivery to the Optic Nerve in a Rodent Model

Tehrani, S., Delf, R. K., Cepurna, W. O., Davis, L., Johnson, E. & Morrison, J., Dec 1 2018, In : Scientific Reports. 8, 1, 4453.

Research output: Contribution to journalArticle

Optic Disk
Optic Nerve
Rodentia
Actins
Optic Nerve Diseases
4 Citations (Scopus)

Rodent retinal circulation organization and oxygen metabolism revealed by visible-light optical coherence tomography

Pi, S., Camino, A., Wei, X., Simonett, J., Cepurna, W., Huang, D., Morrison, J. & Yali, J., Nov 1 2018, In : Biomedical Optics Express. 9, 11, p. 5851-5862 12 p., #345706.

Research output: Contribution to journalArticle

oxygen metabolism
rodents
Optical Coherence Tomography
metabolism
Rodentia
7 Citations (Scopus)

The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography

Jiang, X., Johnson, E., Cepurna, W., Lozano, D., Men, S., Wang, R. K. & Morrison, J., Jan 1 2018, In : Microvascular Research. 115, p. 12-19 8 p.

Research output: Contribution to journalArticle

Angiography
Optical tomography
Optical Coherence Tomography
Intraocular Pressure
Animals

Utilizing RNA-seq to identify differentially expressed genes in glaucoma model tissues, such as the rodent optic nerve head

Lozano, D. C., Choi, D., Jayaram, H., Morrison, J. & Johnson, E., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1695. p. 299-310 12 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceedingChapter

RNA Sequence Analysis
Optic Disk
Intraocular Pressure
Glaucoma
Retina
2017
9 Citations (Scopus)

Angiographic and structural imaging using high axial resolution fiber-based visible-light OCT

Pi, S., Camino, A., Zhang, M., Cepurna, W., Liu, G., Huang, D., Morrison, J. & Yali, J., Oct 1 2017, In : Biomedical Optics Express. 8, 10, p. 4595-4608 14 p., #304064.

Research output: Contribution to journalArticle

retina
rats
Retina
chickens
embryos
1 Citation (Scopus)
Aqueous Humor
MicroRNAs
Polymerase Chain Reaction
Primary Open Angle Glaucoma
3 Citations (Scopus)
retina
edge detection
Optic Disk
Optical Coherence Tomography
Retina
18 Citations (Scopus)

Biological aspects of axonal damage in glaucoma: A brief review

Tamm, E. R., Ethier, C. R., Dowling, J. E., Downs, C., Ellisman, M. H., Fisher, S., Fortune, B., Fruttiger, M., Jakobs, T., Lewis, G., Mitchell, C. H., Morrison, J., Morrison, J., Sigal, I., Sofroniew, M., Wang, L., Wiggs, J., Wu, S. & Masland, R. H., Jan 22 2017, (Accepted/In press) In : Experimental Eye Research.

Research output: Contribution to journalArticle

Optic Disk
Glaucoma
Intraocular Pressure
Sclera
Astrocytes
15 Citations (Scopus)

Biomechanical aspects of axonal damage in glaucoma: A brief review

The Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration Participants, Apr 1 2017, In : Experimental Eye Research. 157, p. 13-19 7 p.

Research output: Contribution to journalReview article

Optic Disk
Glaucoma
Intraocular Pressure
Biomechanical Phenomena
Astrocytes
9 Citations (Scopus)

Comparison of microRNA expression in aqueous humor of normal and primary open-angle glaucoma patients using PCR arrays: A pilot study

Jayaram, H., Phillips, J. I., Lozano, D. C., Choe, T. E., Cepurna, W. O., Johnson, E., Morrison, J., Gattey, D. M., Saugstad, J. & Keller, K., Jun 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 7, p. 2884-2890 7 p.

Research output: Contribution to journalArticle

Aqueous Humor
MicroRNAs
Polymerase Chain Reaction
Primary Open Angle Glaucoma
Encyclopedias
44 Citations (Scopus)

Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma

Takusagawa, H., Liu, L., Ma, K. N., Yali, J., Gao, S. S., Zhang, M., Edmunds, L. B., Parikh, M., Tehrani, S., Morrison, J. & Huang, D., 2017, (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Glaucoma
Blood Vessels
Angiography
Visual Fields
2016
11 Citations (Scopus)

A period of controlled elevation of IOP (CEI) produces the specific gene expression responses and focal injury pattern of experimental rat glaucoma

Morrison, J., Cepurna, W. O., Tehrani, S., Choe, T. E., Jayaram, H., Lozano, D. C., Fortune, B. & Johnson, E., Dec 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 15, p. 6700-6711 12 p.

Research output: Contribution to journalArticle

Optic Disk
Glaucoma
Gene Expression
Optic Nerve
Wounds and Injuries
12 Citations (Scopus)

Astrocyte structural and molecular response to elevated intraocular pressure occurs rapidly and precedes axonal tubulin rearrangement within the optic nerve head in a rat model

Tehrani, S., Davis, L., Cepurna, W. O., Choe, T. E., Lozano, D. C., Monfared, A., Cooper, L., Cheng, J., Johnson, E. & Morrison, J., Nov 1 2016, In : PLoS One. 11, 11, e0167364.

Research output: Contribution to journalArticle

astrocytes
Optic Disk
Tubulin
optics
tubulin
24 Citations (Scopus)

Compensation for reflectance variation in vessel density quantification by optical coherence tomography angiography

Gao, S. S., Yali, J., Liu, L., Zhang, M., Takusagawa, H., Morrison, J. & Huang, D., Aug 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4485-4492 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Angiography
Noise
Optic Disk
Blood Vessels
10 Citations (Scopus)

Expansions of the neurovascular scleral canal and contained optic nerve occur early in the hypertonic saline rat experimental glaucoma model

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E., Morrison, J. & Burgoyne, C. F., Apr 1 2016, In : Experimental Eye Research. 145, p. 173-186 14 p.

Research output: Contribution to journalArticle

Optic Nerve
Glaucoma
Theoretical Models
Optic Disk
Nerve Expansion
17 Citations (Scopus)

Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism

Teotia, P., Chopra, D. A., Dravid, S. M., Van Hook, M. J., Qiu, F., Morrison, J., Rizzino, A. & Ahmad, I., 2016, (Accepted/In press) In : Stem Cells.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Retinal Ganglion Cells
Stem Cells
Induced Pluripotent Stem Cells
Embryonic Stem Cells
3 Citations (Scopus)
Optical Coherence Tomography
Glaucoma
Nerve Fibers
Visual Field Tests
Optic Disk

Optic nerve: Atypical nerves and nerve findings

Edmunds, L. B. & Morrison, J., Jan 1 2016, Pearls of Glaucoma Management: Second Edition. Springer Berlin Heidelberg, p. 71-83 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Optics
2015
7 Citations (Scopus)

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy

Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I., Jun 1 2015, In : Stem Cells. 33, 6, p. 1743-1758 16 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Induced Pluripotent Stem Cells
Glaucoma
Ocular Hypertension
Acids
18 Citations (Scopus)
Optical tomography
Optical Coherence Tomography
Intraocular Pressure
Rats
Blood
18 Citations (Scopus)

Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene

Ying, H. H., Turturro, S. S., Nguyen, T. T., Shen, X. X., Zelkha, R. R., Johnson, E., Morrison, J. & Yue, B. B. Y. J. T., May 6 2015, In : BMC Cell Biology. 16, 1, 14.

Research output: Contribution to journalArticle

Autophagy
Proteasome Endopeptidase Complex
Ubiquitin
Retinal Ganglion Cells
Fluorescence
2 Citations (Scopus)

Introduction to special issue on glaucomatous optic neuropathy: In vivo models and techniques

Ethier, C. R., Morrison, J. & Clark, A. F., Jul 20 2015, In : Experimental Eye Research. 141, p. 1-2 2 p.

Research output: Contribution to journalArticle

Animal Disease Models
Optic Nerve Diseases
Optic Nerve
Intraocular Pressure
Glaucoma
13 Citations (Scopus)

MicroRNA expression in the glaucomatous retina

Jayaram, H., Cepurna, W. O., Johnson, E. & Morrison, J., Dec 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 13, p. 7971-7982 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Retina
Intraocular Pressure
Central Nervous System
Chemical Databases
19 Citations (Scopus)

Modeling glaucoma in rats by sclerosing aqueous outflow pathways to elevate intraocular pressure

Morrison, J., Cepurna, W. O. & Johnson, E., Mar 28 2015, In : Experimental Eye Research. 141, p. 23-32 10 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Glaucoma
Aqueous Humor
Optic Disk
Injections
255 Citations (Scopus)

Optical coherence tomography angiography of the peripapillary retina in glaucoma

Liu, L., Yali, J., Takusagawa, H., Pechauer, A. D., Edmunds, L. B., Lombardi, L., Davis, E., Morrison, J. & Huang, D., Sep 1 2015, In : JAMA Ophthalmology. 133, 9, p. 1045-1052 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Glaucoma
Retina
Angiography
Perfusion
25 Citations (Scopus)

Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye

Lu, W., Hu, H., Sévigny, J., Gabelt, B. T., Kaufman, P. L., Johnson, E., Morrison, J., Zode, G. S., Sheffield, V. C., Zhang, X., Laties, A. M. & Mitchell, C. H., 2015, In : Investigative Ophthalmology and Visual Science. 56, 5, p. 3075-3083 9 p.

Research output: Contribution to journalArticle

Glaucoma
Primates
Adenosine Triphosphate
Astrocytes
Retinal Neurons
12 Citations (Scopus)

Rat optic nerve head anatomy within 3D histomorphometric reconstructions of normal control eyes

Pazos, M., Yang, H., Gardiner, S. K., Cepurna, W. O., Johnson, E., Morrison, J. & Burgoyne, C. F., Oct 1 2015, In : Experimental Eye Research. 139, p. 1-12 12 p.

Research output: Contribution to journalArticle

Bruch Membrane
Optic Disk
Anatomy
Retinal Vein
Sclera
2014
23 Citations (Scopus)

An acute intraocular pressure challenge to assess retinal ganglion cell injury and recovery in the mouse

Crowston, J. G., Kong, Y. X. G., Trounce, I. A., Dang, T. M., Fahy, E. T., Bui, B. V., Morrison, J. & Chrysostomou, V., Dec 12 2014, In : Experimental Eye Research. 141, p. 3-8 6 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Intraocular Pressure
Wounds and Injuries
Neuroglia
Glaucoma
19 Citations (Scopus)
Optic Disk
Astrocytes
Glaucoma
Actins
Optic Nerve
344 Citations (Scopus)

Optical coherence tomography angiography of optic disc perfusion in glaucoma

Yali, J., Wei, E., Wang, X., Zhang, X., Morrison, J., Parikh, M., Lombardi, L., Gattey, D. M., Armour, R. L., Edmunds, L. B., Kraus, M. F., Fujimoto, J. G. & Huang, D., 2014, In : Ophthalmology. 121, 7, p. 1322-1332 11 p.

Research output: Contribution to journalArticle

Optic Disk
Optical Coherence Tomography
Glaucoma
Angiography
Perfusion
12 Citations (Scopus)

Radiation pretreatment does not protect the rat optic nerve from elevated intraocular pressure–induced injury

Johnson, E., Cepurna, W. O., Choi, D., Choe, T. E. & Morrison, J., Dec 7 2014, In : Investigative Ophthalmology and Visual Science. 56, 1, p. 412-419 8 p.

Research output: Contribution to journalArticle

Optic Nerve
Intraocular Pressure
Radiation
Wounds and Injuries
Glaucoma
2013
16 Citations (Scopus)

Electronic health record systems in ophthalmology: Impact on clinical documentation

Sanders, D. S., Lattin, D. J., Read-Brown, S., Tu, D., Wilson, D., Hwang, T., Morrison, J., Yackel, T. & Chiang, M., Sep 2013, In : Ophthalmology. 120, 9, p. 1745-1755 11 p.

Research output: Contribution to journalArticle

Electronic Health Records
Ophthalmology
Documentation
Glaucoma
Matched-Pair Analysis
29 Citations (Scopus)
Electronic Health Records
Ophthalmology
Documentation
Databases
Population
2012
50 Citations (Scopus)

Impact of intraocular pressure on changes of blood flow in the retina, choroid, and optic nerve head in rats investigated by optical microangiography

Zhi, Z., Cepurna, W. O., Johnson, E., Morrison, J. & Wang, R. K., Sep 1 2012, In : Biomedical Optics Express. 3, 9, p. 2220-2233 14 p.

Research output: Contribution to journalArticle

intraocular pressure
Choroid
retina
Optic Disk
nerves
230 Citations (Scopus)

Quantitative OCT angiography of optic nerve head blood flow

Yali, J., Morrison, J., Tokayer, J., Tan, O., Lombardi, L., Baumann, B., Lu, C. D., Choi, W., Fujimoto, J. G. & Huang, D., Dec 1 2012, In : Biomedical Optics Express. 3, 12, p. 3127-3137 11 p.

Research output: Contribution to journalArticle

angiography
Optic Disk
Optical Coherence Tomography
nerves
blood flow
2011
73 Citations (Scopus)

Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma

Johnson, E., Doser, T. A., Cepurna, W. O., Dyck, J. A., Jia, L., Guo, Y., Lambert, W. S. & Morrison, J., Jan 2011, In : Investigative Ophthalmology and Visual Science. 52, 1, p. 504-518 15 p.

Research output: Contribution to journalArticle

Optic Nerve Injuries
Optic Disk
Craniocerebral Trauma
Glaucoma
Interleukin-6
44 Citations (Scopus)

Early gene expression changes in the retinal ganglion cell layer of a rat glaucoma model

Guo, Y., Johnson, E., Cepurna, W. O., Dyck, J. A., Doser, T. & Morrison, J., Mar 2011, In : Investigative Ophthalmology and Visual Science. 52, 3, p. 1460-1473 14 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Glaucoma
Gene Expression
Ganglia
Genes