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Eric Barklis

Professor

  • 2998 Citations
  • 32 h-Index
1981 …2020
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  • 3 Similar Profiles
HIV-1 Medicine & Life Sciences
gag Gene Products Medicine & Life Sciences
Moloney murine leukemia virus Medicine & Life Sciences
Capsid Proteins Medicine & Life Sciences
Capsid Medicine & Life Sciences
Virion Medicine & Life Sciences
Retroviridae Medicine & Life Sciences
Murine leukemia virus Agriculture & Biology

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Projects 1988 2020

HIV GAG PRECURSOR PROTEIN INTERACTIONS

Barklis, E.

National Institutes of Health

9/1/99 → 4/30/20

Project: Research project

gag Gene Products
Human Immunodeficiency Virus Proteins
HIV-1
Human Immunodeficiency Virus gag Gene Products
Virion

Analysis of HIV-1 core assembly and inhibition

Barklis, E.

National Institutes of Health

9/30/12 → 7/31/16

Project: Research project

HIV-1
Morphogenesis
HIV
Antiviral Agents
Viruses

Development of Novel Small Molecule Flavivirus Inhibitors

Barklis, E.

National Institutes of Health

3/1/09 → 2/28/12

Project: Research project

Flavivirus
West Nile virus
Thiourea
Antiviral Agents
Japanese Encephalitis Virus

Development of a high throughput HIV assembly screen

Barklis, E.

National Institutes of Health

7/1/07 → 6/30/12

Project: Research project

HIV
High-Throughput Screening Assays
Small Molecule Libraries
Signal-To-Noise Ratio
Public Health

Analysis of Sin Nombre virus inhibition in lung cells

Barklis, E.

National Institutes of Health

4/1/04 → 3/31/08

Project: Research project

Sin Nombre virus
Hantavirus
Lung
Hantavirus Pulmonary Syndrome
Nucleosides

Research Output 1981 2019

  • 2998 Citations
  • 32 h-Index
  • 77 Article
  • 1 Chapter
  • 1 Conference contribution

Organization of Farnesylated, Carboxymethylated KRAS4B on Membranes

Barklis, E., Stephen, A. G., Staubus, A. O., Barklis, R. L. & Alfadhli, A., Jan 1 2019, In : Journal of molecular biology.

Research output: Contribution to journal › Article

Membranes
Proteins
Prenylation
ras Proteins
Post Translational Protein Processing

Lipid biosensor interactions with wild type and matrix deletion HIV-1 Gag proteins

Barklis, E., Staubus, A. O., Mack, A., Harper, L., Barklis, R. L. & Alfadhli, A., May 1 2018, In : Virology. 518, p. 264-271 8 p.

Research output: Contribution to journal › Article

gag Gene Products
Biosensing Techniques
HIV-1
Lipids
Viral Proteins
1 Citation (Scopus)

Analysis of K-Ras interactions by biotin ligase tagging

Ritchie, C., Mack, A., Harper, L., Alfadhli, A., Stork, P., Nan, X. & Barklis, E., Jul 1 2017, In : Cancer Genomics and Proteomics. 14, 4, p. 225-239 15 p.

Research output: Contribution to journal › Article

Ligases
Biotin
ras Proteins
Cells
Prenylation
3 Citations (Scopus)

Analysis of quinolinequinone reactivity, cytotoxicity, and anti-HIV-1 properties

Alfadhli, A., Mack, A., Harper, L., Berk, S., Ritchie, C. & Barklis, E., Nov 1 2016, In : Bioorganic and Medicinal Chemistry. 24, 21, p. 5618-5625 8 p.

Research output: Contribution to journal › Article

Cytotoxicity
HIV-1
Viruses
Proteins
Crosslinking
3 Citations (Scopus)

Trimer enhancement mutation effects on HIV-1 matrix protein binding activities

Alfadhli, A., Mack, A., Ritchie, C., Cylinder, I., Harper, L., Tedbury, P. R., Freed, E. O. & Barklis, E., Jun 1 2016, In : Journal of Virology. 90, 12, p. 5657-5664 8 p.

Research output: Contribution to journal › Article

protein binding
Human immunodeficiency virus 1
Protein Binding
HIV-1
mutation