David Farrens

Associate Professor

  • 4840 Citations
  • 34 h-Index
1989 …2019
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  • 1 Similar Profiles
Rhodopsin Medicine & Life Sciences
Phytochrome Medicine & Life Sciences
Fluorescence Medicine & Life Sciences
Arrestin Medicine & Life Sciences
Transducin Medicine & Life Sciences
Cysteine Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Labeling Chemical Compounds

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Projects 1993 2015

Protein folding
Signal transduction
Dye lasers
Cannabinoid Receptors
Cannabinoid Receptor CB1
Street Drugs

Research Output 1989 2019

  • 4840 Citations
  • 34 h-Index
  • 63 Article
  • 2 Chapter
31 Citations (Scopus)

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

Krishna Kumar, K., Shalev-Benami, M., Robertson, M. J., Hu, H., Banister, S. D., Hollingsworth, S. A., Latorraca, N. R., Kato, H. E., Hilger, D., Maeda, S., Weis, W. I., Farrens, D., Dror, R. O., Malhotra, S. V., Kobilka, B. K. & Skiniotis, G., Jan 24 2019, In : Cell. 176, 3, p. 448-458.e12

Research output: Contribution to journalArticle

Cannabinoid Receptors
GTP-Binding Proteins
Chemical activation
Heterotrimeric GTP-Binding Proteins

Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

Arttamangkul, S., Plazek, A., Platt, E. J., Jin, H., Murray, T. F., Birdsong, W. T., Rice, K. C., Farrens, D. L. & Williams, J. T., Oct 7 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Opioid Receptors
Fluorescent Dyes
5 Citations (Scopus)

Single Proteoliposome High Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs

Walsh, S. M., Mathiasen, S., Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, S. G. F., Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. & Stamou, D., Jan 1 2018, (Accepted/In press) In : Biophysical Journal.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
CCR10 Receptors
Cannabinoid Receptors
3 Citations (Scopus)

Purification of Functional CB1 and Analysis by Site-Directed Fluorescence Labeling Methods

Fay, J. F. & Farrens, D., 2017, Methods in Enzymology. Academic Press Inc., Vol. 593. p. 343-370 28 p. (Methods in Enzymology; vol. 593).

Research output: Chapter in Book/Report/Conference proceedingChapter

101 Citations (Scopus)

Biosensor reveals multiple sources for mitochondrial NAD+

Cambronne, X., Stewart, M. L., Kim, D., Jones-Brunette, A. M., Morgan, R. K., Farrens, D., Cohen, M. & Goodman, R., Jun 17 2016, In : Science. 352, 6292, p. 1474-1477 4 p.

Research output: Contribution to journalArticle

Biosensing Techniques