Charles Lopez

Associate Professor

  • 920 Citations
  • 17 h-Index
1990 …2019
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Fingerprint Dive into the research topics where Charles Lopez is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Apoptosis Medicine & Life Sciences
Colorectal Neoplasms Medicine & Life Sciences
irinotecan Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
gemcitabine Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Proteins Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences

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Projects 2000 2010

Carrier Proteins
DNA Damage

Research Output 1990 2019

  • 920 Citations
  • 17 h-Index
  • 32 Article
  • 3 Review article
11 Citations (Scopus)

Activation of PP2A and inhibition of mTOR synergistically reduce MYC signaling and decrease tumor growth in pancreatic ductal adenocarcinoma

Allen-Petersen, B. L., Risom, T., Feng, Z., Wang, Z., Jenny, Z. P., Thoma, M. C., Pelz, K. R., Morton, J. P., Sansom, O. J., Lopez, C., Sheppard, B., Christensen, D. J., Ohlmeyer, M., Narla, G. & Sears, R., Jan 1 2019, In : Cancer Research. 79, 1, p. 209-219 11 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Phosphoric Monoester Hydrolases

Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia

Schittenhelm, M. M., Walter, B., Tsintari, V., Federmann, B., Bajrami Saipi, M., Akmut, F., Illing, B., Mau-Holzmann, U., Fend, F., Lopez, C. & Kampa-Schittenhelm, K. M., Apr 1 2019, In : EBioMedicine. 42, p. 340-351 12 p.

Research output: Contribution to journalArticle

Open Access
Tumor Suppressor Protein p53
Alternative Splicing
Protein Isoforms

A Phase II Study Alternating Erlotinib With Second-line mFOLFOX6 or FOLFIRI for Metastatic Colorectal Cancer

Kearney, M. R., Chen, E. Y., Vaccaro, G., Strother, J., Burt, A., Todd, K., Donovan, J., Kampa-Schittenhelm, K. M. & Lopez, C., Jan 1 2019, In : Anticancer Research. 39, 1, p. 245-252 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Combination Drug Therapy

Evolving Treatment Options and Future Directions for Locally Advanced Rectal Cancer

Chen, E. Y., Kardosh, A., Nabavizadeh, N. & Lopez, C., Jan 1 2019, In : Clinical Colorectal Cancer.

Research output: Contribution to journalReview article

Rectal Neoplasms
Neoadjuvant Therapy
Radiation-Sensitizing Agents
Neoplasm Metastasis
Drug Therapy
5 Citations (Scopus)

A Phase II Study of Celecoxib with Irinotecan, 5-Fluorouracil, and Leucovorin in Patients with Previously Untreated Advanced or Metastatic Colorectal Cancer

Chen, E. Y., Blanke, C., Haller, D. G., Benson, A. B., Dragovich, T., Lenz, H. J., Robles, C., Li, H., Mori, M. T., Mattek, N., Sanborn, R. E. & Lopez, C., Dec 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 12, p. 1193-1198 6 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms