Brian Druker

Professor

  • 63942 Citations
  • 108 h-Index
1981 …2019
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  • 29 Similar Profiles
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Tyrosine Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Mutation Medicine & Life Sciences
Piperazines Medicine & Life Sciences
Leukemia Medicine & Life Sciences

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Projects 1987 2017

Small Interfering RNA
Leukemia
Neoplasms
RNA Interference
Gene Expression

Cancer and Kinases

Druker, B.

National Institutes of Health

9/1/058/31/06

Project: Research project

Phosphotransferases
Pharmaceutical Preparations
Neoplasms
Clinical Trials
Enzymes
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Antineoplastic Agents
Protein-Tyrosine Kinases
Clinical Trials, Phase I
Hematopoietic Stem Cells
Tyrosine
Phosphorylation
src Homology Domains
Protein-Tyrosine Kinases
Research Personnel

Research Output 1981 2019

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 othersBorthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. & Tyner, J., Dec 1 2019, In : Nature Communications. 10, 1, 244.

Research output: Contribution to journalArticle

leukemias
mutations
Acute Myeloid Leukemia
Mutation
inhibitors

Erratum: Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells (eLife (2019) 8 PII: e47174)

Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribeiro, R., Viola, S. K., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Mar 29 2019, In : eLife. 8

Research output: Contribution to journalComment/debate

Open Access
Exosomes
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Medicine
Bone

FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells

Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribiero, R., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Feb 5 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Exosomes
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Protein-Tyrosine Kinases
Bone
1 Citation (Scopus)

Predicting response to BET inhibitors using computational modeling: A BEAT AML project study

Drusbosky, L. M., Vidva, R., Gera, S., Lakshminarayana, A. V., Shyamasundar, V. P., Agrawal, A. K., Talawdekar, A., Abbasi, T., Vali, S., Tognon, C. E., Kurtz, S. E., Tyner, J., McWeeney, S., Druker, B. & Cogle, C. R., Feb 1 2019, In : Leukemia Research. 77, p. 42-50 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Genomics
Computational Biology
MAP Kinase Signaling System
Chromosome Aberrations

Reply to n. Cerveira et al

Berman, E., Druker, B. & Burwick, R., Jan 1 2019, In : Journal of Clinical Oncology. 37, 1, 1 p.

Research output: Contribution to journalLetter