Brian Druker


  • 65521 Citations
  • 110 h-Index
1981 …2019
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  • 28 Similar Profiles
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Tyrosine Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Mutation Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Myeloid Cells Medicine & Life Sciences

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Projects 1987 2017

Research Output 1981 2019

1 Citation (Scopus)

Challenges and approaches to implementing master/basket trials in oncology

Burd, A., Schilsky, R. L., Byrd, J. C., Levine, R. L., Papadimitrakopoulou, V. A., Herbst, R. S., Redman, M. W., Druker, B. & Gandara, D. R., Jul 23 2019, In : Blood Advances. 3, 14, p. 2237-2243 7 p.

Research output: Contribution to journalArticle

Open Access
Research Personnel
Health Personnel
11 Citations (Scopus)

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 others, Borthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. & Tyner, J., Dec 1 2019, In : Nature Communications. 10, 1, 244.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
1 Citation (Scopus)

Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants

Eide, C. A., Zabriskie, M. S., Savage Stevens, S. L., Antelope, O., Vellore, N. A., Than, H., Schultz, A. R., Clair, P., Bowler, A. D., Pomicter, A. D., Yan, D., Senina, A. V., Qiang, W., Kelley, T. W., Szankasi, P., Heinrich, M. C., Tyner, J. W., Rea, D., Cayuela, J. M., Kim, D. W. & 4 others, Tognon, C. E., O'Hare, T., Druker, B. J. & Deininger, M. W., Oct 14 2019, In : Cancer Cell. 36, 4, p. 431-443.e5

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Adenosine Triphosphate

Differentiation of leukemic blasts is not completely blocked in acute myeloid leukemia

Agarwal, A., Bolosky, W. J., Wilson, D. B., Eide, C. A., Olson, S. B., Fan, G. & Druker, B. J., Dec 3 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24593-24599 7 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Hematopoietic Stem Cells
Blood Cells
Myeloid Cells

Erratum: Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells (eLife (2019) 8 PII: e47174)

Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribeiro, R., Viola, S. K., Edwards, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J., Druker, B. & Traer, E., Mar 29 2019, In : eLife. 8

Research output: Contribution to journalComment/debate

Open Access
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells