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  • 24 Similar Profiles
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Tyrosine Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Mutation Medicine & Life Sciences
Piperazines Medicine & Life Sciences
bcr-abl Fusion Proteins Medicine & Life Sciences

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Projects 1987 2017

MUTAGENESIS OF POLYOMA MIDDLE-T ANTIGEN

Druker, B.

National Institutes of Health

4/13/87 → …

Project: Research projectPostdoctoral Individual National Research Service Award

Accelerating target identification and validation in leukemia: Integrating siRNA-

Druker, B.

National Institutes of Health

9/30/098/31/11

Project: Research projectNIH Challenge Grants and Partnerships Program

Small Interfering RNA
Leukemia
Neoplasms
RNA Interference
Gene Expression

Cancer and Kinases

Druker, B.

National Institutes of Health

9/1/058/31/06

Project: Research projectConference

Phosphotransferases
Pharmaceutical Preparations
Neoplasms
Clinical Trials
Enzymes

TYROSINE KINASE INHIBITORS AS ANTINEOPLASTIC AGENTS

Druker, B.

National Institutes of Health

7/9/996/30/04

Project: Research projectMidcareer Investigator Award in Patient-Oriented Research

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Antineoplastic Agents
Protein-Tyrosine Kinases
Clinical Trials, Phase I
Hematopoietic Stem Cells

CBL FUNCTION IN CELLULAR SIGNALING AND TRANSFORMATION

Druker, B.

National Institutes of Health

1/1/9912/31/04

Project: Research projectResearch Project

Tyrosine
Phosphorylation
src Homology Domains
Protein-Tyrosine Kinases
Research Personnel

Research Output 1981 2018

  • 60551 Citations
  • 104 h-Index
  • 418 Article
  • 4 Chapter
  • 3 Letter
  • 1 Comment/debate

A novel AGGF1-PDGFRβ fusion in pediatric T-cell acute lymphoblastic leukemia

Zabriskie, M. S., Antelope, O., Verma, A. R., Draper, L. R., Eide, C. A., Pomicter, A. D., Tran, T. H., Druker, B. J., Tyner, J. W., Miles, R. R., Graham, J. M., Hwang, J. Y., Varley, K. E., Toydemir, R. M., Deininger, M. W., Raetz, E. A. & O’Hare, T. Jan 31 2018 In : Haematologica. 103, 2, p. e87-e91

Research output: Contribution to journalComment/debate

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics

Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms

MacHado-Neto, J. A., Fenerich, B. A., Scopim-Ribeiro, R., Eide, C. A., Coelho-Silva, J. L., Dechandt, C. R. P., Fernandes, J. C., Rodrigues Alves, A. P. N., Scheucher, P. S., Simões, B. P., Alberici, L. C., De Figueiredo Pontes, L. L., Tognon, C. E., Druker, B. J., Rego, E. M. & Traina, F. Mar 1 2018 In : Cell Death and Disease. 9, 3, 311

Research output: Contribution to journalArticle

Metformin
Neoplasms
Polycythemia Vera
Cell Survival
Cell Proliferation
3 Citations

Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: Findings and recommendations

Watanabe-Smith, K., Godil, J., Agarwal, A., Tognon, C. & Druker, B. 2017 In : Oncotarget. 8, 8, p. 12596-12606 11 p.

Research output: Contribution to journalArticle

Transgenes
Mutation
Intercellular Signaling Peptides and Proteins
Leukemia
Cytokine Receptors
1 Citations
Large Granular Lymphocytic Leukemia
Hematopoiesis
Mutation
2 Citations

CRISPR-Cas9–mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy

Ma, L., Boucher, J. I., Paulsen, J., Matuszewski, S., Eide, C. A., Ou, J., Eickelberg, G., Press, R. D., Zhu, L. J., Druker, B. J., Branford, S., Wolfe, S. A., Jensen, J. D., Schiffer, C. A., Green, M. R. & Bolon, D. N. Oct 31 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 44, p. 11751-11756 6 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Drug Resistance
Mutagenesis
Mutation
Oncogenes