Andrei Pugachev

Assistant Professor

  • 860 Citations
  • 10 h-Index
19992017
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Research Output 1999 2017

  • 860 Citations
  • 10 h-Index
  • 28 Article
  • 2 Conference article
  • 1 Letter
  • 1 Review article
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Article
2014
3 Citations (Scopus)

An alternative approach to histopathological validation of PET imaging for radiation therapy image-guidance: A proof of concept

Axente, M., He, J., Bass, C. P., Sundaresan, G., Zweit, J., Williamson, J. F. & Pugachev, A., Jan 1 2014, In : Radiotherapy and Oncology. 110, 2, p. 309-316 8 p.

Research output: Contribution to journalArticle

Radiotherapy
Neoplasms
Autoradiography
Tissue Distribution
Microscopy
2013

WE‐E‐108‐11: PET‐Guided Selective Dose Escalation for a Small Animal Tumor Model

Bass, C., Axente, M., he, J., Gobalakrishnan, S., Zweit, J., Hugo, G. & Pugachev, A., Jan 1 2013, In : Medical Physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

Animal Models
Radiation
Neoplasms
Tumor Burden
Heterografts
2012
2 Citations (Scopus)

Single-fraction simulation of relative cell survival in response to uniform versus hypoxia-targeted dose escalation

Axente, M., Lin, P. S. & Pugachev, A., May 7 2012, In : Physics in Medicine and Biology. 57, 9, p. 2757-2774 18 p.

Research output: Contribution to journalArticle

Cell Survival
Neoplasms
Microvessels
Hypoxia
Oxygen
1 Citation (Scopus)

SU‐D‐217A‐04: Evaluation of the Spatial Concordance Between the Intratumoral Patterns of 18F‐FLT and 18F‐FDG Uptake in a Small Animal Tumor Model

Bass, C., Axente, M., he, J., Sundaresan, G., Hirsch, J., Hugo, G., Zweit, J. & Pugachev, A., Jan 1 2012, In : Medical Physics. 39, 6, 1 p.

Research output: Contribution to journalArticle

Animal Models
Neoplasms
Tumor Microenvironment
Tissue Survival
Heterografts

TH‐E‐BRA‐02: A Novel Approach to Histopathological Validation of PET Tracers for Image Guidance in Radiotherapy

Axente, M., he, J., Bass, C., Sundaresan, G., Zweit, J., Williamson, J. & Pugachev, A., Jan 1 2012, In : Medical Physics. 39, 6, p. 4011-4012 2 p.

Research output: Contribution to journalArticle

Radiotherapy
Neoplasms
Photography
Tissue Distribution
Autoradiography
5 Citations (Scopus)

Tumour microenvironment heterogeneity affects the perceived spatial concordance between the intratumoural patterns of cell proliferation and 18F-fluorothymidine uptake

Axente, M., He, J., Bass, C. P., Hirsch, J. I., Sundaresan, G., Williamson, J., Zweit, J. & Pugachev, A., Oct 1 2012, In : Radiotherapy and Oncology. 105, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Cell Proliferation
Neoplasms
Bromodeoxyuridine
Heterografts
2011
7 Citations (Scopus)

Comprehensive approach to coregistration of autoradiography and microscopy images acquired from a set of sequential tissue sections

Axente, M., He, J., Bass, C. P., Hirsch, J. I., Sundaresan, G., Zweit, J. & Pugachev, A., Oct 1 2011, In : Journal of Nuclear Medicine. 52, 10, p. 1621-1629 9 p.

Research output: Contribution to journalArticle

Open Access
Autoradiography
Microscopy
Neoplasms
Tumor Microenvironment
Hematoxylin

SU‐C‐211‐08: Deformable Registration and Analysis of Small Animal 18F‐FLT and 18F‐FDG PET/CT Images

Bass, C., Axente, M., he, J., Gobalakrishnan, S., Hirsch, J., Hugo, G., Zweit, J. & Pugachev, A., Jan 1 2011, In : Medical Physics. 38, 6, 1 p.

Research output: Contribution to journalArticle

Anatomy
Heterografts
Nude Mice
Neoplasms
Datasets

SU‐F‐BRA‐01: Object‐Based Analysis of Spatial Concordance Between Coregistered Images of Intratumoral Uptake of [18F]FLT and Distribution of Cell Proliferation Markers

Axente, M., he, J., Bass, C., Gobalakrishnan, S., Hirsch, J., Zweit, J. & Pugachev, A., Jan 1 2011, In : Medical Physics. 38, 6, p. 3699-3700 2 p.

Research output: Contribution to journalArticle

Spatial Analysis
Autoradiography
Cell Proliferation
Neoplasms
Microscopy

TH‐B‐224‐01: PET Imaging of Tumor Microenvironment for Radiation Treatment Planning

Pugachev, A., Jan 1 2011, In : Medical Physics. 38, 6, 1 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Positron-Emission Tomography
Radiation
Therapeutics
Tissue Survival
2010
Radiation
Neoplasms
Therapeutics
Prescriptions
Oxygen

TH‐C‐202‐02: Positron Emission Tomography Imaging for Radiation Treatment Planning

Pugachev, A., Jan 1 2010, In : Medical Physics. 37, 6, 1 p.

Research output: Contribution to journalArticle

Radiation Oncology
Positron-Emission Tomography
Radiation
Learning
Therapeutics
2009
14 Citations (Scopus)

In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression

Carlin, S., Pugachev, A., Sun, X., Burke, S., Claus, F., O'Donoghue, J., Ling, C. C. & Humm, J. L., Oct 1 2009, In : Nuclear Medicine and Biology. 36, 7, p. 821-831 11 p.

Research output: Contribution to journalArticle

Reporter Genes
Gene Expression
Neoplasms
Spatial Analysis
Staining and Labeling

SU‐GG‐BRC‐05: The Role of Hypoxia in Radiation Treatment Planning. A Simulation Study

Axente, M., Lin, P. & Pugachev, A., Jan 1 2009, In : Medical Physics. 36, 6, 1 p.

Research output: Contribution to journalArticle

Radiation
Neoplasms
Therapeutics
Hypoxia
Linear Models
2008

SU‐GG‐J‐109: Inhomogeneities of Intratumoral FDG Uptake in Human Colon Adenocarcinoma HT29 Tumor Model

Pugachev, A., Sun, X., Carlin, S. & Humm, J., Jan 1 2008, In : Medical Physics. 35, 6, 1 p.

Research output: Contribution to journalArticle

Colon
Adenocarcinoma
Bromodeoxyuridine
Neoplasms
Fluorodeoxyglucose F18
2007

TH‐C‐L100J‐07: Causes of Inhomogeneities of Intratumoral FDG Uptake

Pugachev, A., Sun, X., Carlin, S. & Humm, J., Jan 1 2007, In : Medical Physics. 34, 6, 1 p.

Research output: Contribution to journalArticle

Neoplasms
Necrosis
Fluorodeoxyglucose F18
Bromodeoxyuridine
Autoradiography

TU‐D‐L100F‐02: PET Biomarkers in Radiation Oncology

Pugachev, A., Jan 1 2007, In : Medical Physics. 34, 6, 1 p.

Research output: Contribution to journalArticle

Radiation Oncology
Biomarkers
Neoplasms
Radiation
Radiotherapy
2006

SU‐FF‐J‐89: Intratumoral Pattern of FDG Uptake in Human Xenograft Models

Pugachev, A., Carlin, S., Ling, C. & Humm, J., Jan 1 2006, In : Medical Physics. 33, 6, 1 p.

Research output: Contribution to journalArticle

Heterografts
Bromodeoxyuridine
Neoplasms
Nude Rats
HT29 Cells
2005
151 Citations (Scopus)

Assessment of regional tumor hypoxia using 18F- fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4- methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models

O'Donoghue, J. A., Zanzonico, P., Pugachev, A., Wen, B., Smith-Jones, P., Cai, S., Burnazi, E., Finn, R. D., Burgman, P., Ruan, S., Lewis, J. S., Welch, M. J., Ling, C. C. & Humm, J. L., Apr 1 2005, In : International Journal of Radiation Oncology Biology Physics. 61, 5, p. 1493-1502 10 p.

Research output: Contribution to journalArticle

autoradiography
Diacetyl
hypoxia
Autoradiography
Positron-Emission Tomography
144 Citations (Scopus)

Dependence of FDG uptake on tumor microenvironment

Pugachev, A., Ruan, S., Carlin, S., Larson, S. M., Campa, J., Ling, C. C. & Humm, J. L., Jun 1 2005, In : International Journal of Radiation Oncology Biology Physics. 62, 2, p. 545-553 9 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
tumors
Fluorodeoxyglucose F18
Bromodeoxyuridine
Neoplasms
1 Citation (Scopus)

MO‐D‐I‐609‐08: Validation of PET Hypoxia Tracers by Autoradiography and Fluorescent Microscopy

Pugachev, A., Claus, F., Sun, X., Ruan, S., Cai, S., Koziorowsky, J., Finn, R., O”donoghue, J., Ling, C. & Humm, J., Jan 1 2005, In : Medical Physics. 32, 6, 1 p.

Research output: Contribution to journalArticle

Autoradiography
Microscopy
Staining and Labeling
Biological Phenomena
Neoplasms
2002
5 Citations (Scopus)

Examination of the effect of increasing the number of radiation beams on a radiation treatment plan

Crooks, S. M., Pugachev, A., King, C. & Xing, L., Oct 7 2002, In : Physics in Medicine and Biology. 47, 19, p. 3485-3501 17 p.

Research output: Contribution to journalArticle

Least-Squares Analysis
Prostate
Neck
Head
Radiation
99 Citations (Scopus)

Incorporating prior knowledge into beam orientaton optimization in IMRT

Pugachev, A. & Xing, L., Dec 1 2002, In : International Journal of Radiation Oncology Biology Physics. 54, 5, p. 1565-1574 10 p.

Research output: Contribution to journalArticle

Intensity-Modulated Radiotherapy
radiation therapy
optimization
sampling
Therapeutics
2001
55 Citations (Scopus)

Computer-assisted selection of coplanar beam orientations in intensity-modulated radiation therapy

Pugachev, A. & Xing, L., Oct 6 2001, In : Physics in Medicine and Biology. 46, 9, p. 2467-2476 10 p.

Research output: Contribution to journalArticle

Radiotherapy
radiation therapy
Organs at Risk
Planning
planning
79 Citations (Scopus)
radiation therapy
Radiotherapy
Organs at Risk
Nasopharyngeal Neoplasms
dosage
112 Citations (Scopus)

Role of beam orientation optimization in intensity-modulated radiation therapy

Pugachev, A., Li, J. G., Boyer, A. L., Hancock, S. L., Le, Q. T., Donaldson, S. S. & Xing, L., Jun 1 2001, In : International Journal of Radiation Oncology Biology Physics. 50, 2, p. 551-560 10 p.

Research output: Contribution to journalArticle

radiation therapy
Radiotherapy
optimization
Tumor Burden
Nasopharyngeal Neoplasms
2000
85 Citations (Scopus)

Beam orientation optimization in intensity-modulated radiation treatment planning

Pugachev, A., Boyer, A. L. & Xing, L., Jan 1 2000, In : Medical Physics. 27, 6, p. 1238-1245 8 p.

Research output: Contribution to journalArticle

Radiotherapy
Radiation
Therapeutics
Weights and Measures
Direction compound
1999
40 Citations (Scopus)

Estimation theory and model parameter selection for therapeutic treatment plan optimization

Xing, L., Li, J. G., Pugachev, A., Le, Q. T. & Boyer, A. L., Jan 1 1999, In : Medical Physics. 26, 11, p. 2348-2358 11 p.

Research output: Contribution to journalArticle

Patient Selection
Systems Analysis
Radiotherapy
Therapeutics