Andrei Pugachev

Assistant Professor

  • 873 Citations
  • 10 h-Index
19992017

Research output per year

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Research Output

  • 873 Citations
  • 10 h-Index
  • 28 Article
  • 2 Conference article
  • 1 Letter
  • 1 Review article
Article

An alternative approach to histopathological validation of PET imaging for radiation therapy image-guidance: A proof of concept

Axente, M., He, J., Bass, C. P., Sundaresan, G., Zweit, J., Williamson, J. F. & Pugachev, A., Feb 2014, In : Radiotherapy and Oncology. 110, 2, p. 309-316 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Assessment of regional tumor hypoxia using 18F- fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4- methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models

O'Donoghue, J. A., Zanzonico, P., Pugachev, A., Wen, B., Smith-Jones, P., Cai, S., Burnazi, E., Finn, R. D., Burgman, P., Ruan, S., Lewis, J. S., Welch, M. J., Ling, C. C. & Humm, J. L., Apr 1 2005, In : International Journal of Radiation Oncology Biology Physics. 61, 5, p. 1493-1502 10 p.

Research output: Contribution to journalArticle

151 Scopus citations

Beam orientation optimization in intensity-modulated radiation treatment planning

Pugachev, A. B., Boyer, A. L. & Xing, L., Jun 2000, In : Medical Physics. 27, 6, p. 1238-1245 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

Comprehensive approach to coregistration of autoradiography and microscopy images acquired from a set of sequential tissue sections

Axente, M., He, J., Bass, C. P., Hirsch, J. I., Sundaresan, G., Zweit, J. & Pugachev, A., Oct 1 2011, In : Journal of Nuclear Medicine. 52, 10, p. 1621-1629 9 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Computer-assisted selection of coplanar beam orientations in intensity-modulated radiation therapy

Pugachev, A. & Xing, L., Oct 6 2001, In : Physics in Medicine and Biology. 46, 9, p. 2467-2476 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Dependence of FDG uptake on tumor microenvironment

Pugachev, A., Ruan, S., Carlin, S., Larson, S. M., Campa, J., Ling, C. C. & Humm, J. L., Jun 1 2005, In : International Journal of Radiation Oncology Biology Physics. 62, 2, p. 545-553 9 p.

Research output: Contribution to journalArticle

145 Scopus citations

Estimation theory and model parameter selection for therapeutic treatment plan optimization

Xing, L., Li, J. G., Pugachev, A., Le, Q. T. & Boyer, A. L., Nov 1999, In : Medical Physics. 26, 11, p. 2348-2358 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Examination of the effect of increasing the number of radiation beams on a radiation treatment plan

Crooks, S. M., Pugachev, A., King, C. & Xing, L., Oct 7 2002, In : Physics in Medicine and Biology. 47, 19, p. 3485-3501 17 p.

Research output: Contribution to journalArticle

5 Scopus citations

Incorporating prior knowledge into beam orientaton optimization in IMRT

Pugachev, A. & Xing, L., Dec 1 2002, In : International Journal of Radiation Oncology Biology Physics. 54, 5, p. 1565-1574 10 p.

Research output: Contribution to journalArticle

101 Scopus citations

In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression

Carlin, S., Pugachev, A., Sun, X., Burke, S., Claus, F., O'Donoghue, J., Ling, C. C. & Humm, J. L., Oct 1 2009, In : Nuclear Medicine and Biology. 36, 7, p. 821-831 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

MO‐D‐I‐609‐08: Validation of PET Hypoxia Tracers by Autoradiography and Fluorescent Microscopy

Pugachev, A., Claus, F., Sun, X., Ruan, S., Cai, S., Koziorowsky, J., Finn, R., O”donoghue, J., Ling, C. & Humm, J., Jun 2005, In : Medical Physics. 32, 6, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations
79 Scopus citations

Role of beam orientation optimization in intensity-modulated radiation therapy

Pugachev, A., Li, J. G., Boyer, A. L., Hancock, S. L., Le, Q. T., Donaldson, S. S. & Xing, L., Jun 1 2001, In : International Journal of Radiation Oncology Biology Physics. 50, 2, p. 551-560 10 p.

Research output: Contribution to journalArticle

115 Scopus citations

Single-fraction simulation of relative cell survival in response to uniform versus hypoxia-targeted dose escalation

Axente, M., Lin, P. S. & Pugachev, A., May 7 2012, In : Physics in Medicine and Biology. 57, 9, p. 2757-2774 18 p.

Research output: Contribution to journalArticle

2 Scopus citations

SU‐C‐211‐08: Deformable Registration and Analysis of Small Animal 18F‐FLT and 18F‐FDG PET/CT Images

Bass, C., Axente, M., he, J., Gobalakrishnan, S., Hirsch, J., Hugo, G., Zweit, J. & Pugachev, A., Jan 1 2011, In : Medical Physics. 38, 6, 1 p.

Research output: Contribution to journalArticle

SU‐D‐217A‐04: Evaluation of the Spatial Concordance Between the Intratumoral Patterns of 18F‐FLT and 18F‐FDG Uptake in a Small Animal Tumor Model

Bass, C., Axente, M., he, J., Sundaresan, G., Hirsch, J., Hugo, G., Zweit, J. & Pugachev, A., Jun 2012, In : Medical Physics. 39, 6, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

SU‐F‐BRA‐01: Object‐Based Analysis of Spatial Concordance Between Coregistered Images of Intratumoral Uptake of [18F]FLT and Distribution of Cell Proliferation Markers

Axente, M., he, J., Bass, C., Gobalakrishnan, S., Hirsch, J., Zweit, J. & Pugachev, A., Jan 1 2011, In : Medical Physics. 38, 6, p. 3699-3700 2 p.

Research output: Contribution to journalArticle

SU‐FF‐J‐89: Intratumoral Pattern of FDG Uptake in Human Xenograft Models

Pugachev, A., Carlin, S., Ling, C. & Humm, J., Jan 1 2006, In : Medical Physics. 33, 6, 1 p.

Research output: Contribution to journalArticle

SU‐GG‐BRC‐05: The Role of Hypoxia in Radiation Treatment Planning. A Simulation Study

Axente, M., Lin, P. & Pugachev, A., Jan 1 2009, In : Medical Physics. 36, 6, 1 p.

Research output: Contribution to journalArticle

SU‐GG‐J‐109: Inhomogeneities of Intratumoral FDG Uptake in Human Colon Adenocarcinoma HT29 Tumor Model

Pugachev, A., Sun, X., Carlin, S. & Humm, J., Jan 1 2008, In : Medical Physics. 35, 6, 1 p.

Research output: Contribution to journalArticle

TH‐B‐224‐01: PET Imaging of Tumor Microenvironment for Radiation Treatment Planning

Pugachev, A., Jan 1 2011, In : Medical Physics. 38, 6, 1 p.

Research output: Contribution to journalArticle

TH‐C‐202‐02: Positron Emission Tomography Imaging for Radiation Treatment Planning

Pugachev, A., Jan 1 2010, In : Medical Physics. 37, 6, 1 p.

Research output: Contribution to journalArticle

TH‐C‐L100J‐07: Causes of Inhomogeneities of Intratumoral FDG Uptake

Pugachev, A., Sun, X., Carlin, S. & Humm, J., Jan 1 2007, In : Medical Physics. 34, 6, 1 p.

Research output: Contribution to journalArticle

TH‐E‐BRA‐02: A Novel Approach to Histopathological Validation of PET Tracers for Image Guidance in Radiotherapy

Axente, M., he, J., Bass, C., Sundaresan, G., Zweit, J., Williamson, J. & Pugachev, A., Jan 1 2012, In : Medical Physics. 39, 6, p. 4011-4012 2 p.

Research output: Contribution to journalArticle

TU‐D‐L100F‐02: PET Biomarkers in Radiation Oncology

Pugachev, A., Jan 1 2007, In : Medical Physics. 34, 6, 1 p.

Research output: Contribution to journalArticle

Tumour microenvironment heterogeneity affects the perceived spatial concordance between the intratumoural patterns of cell proliferation and 18F-fluorothymidine uptake

Axente, M., He, J., Bass, C. P., Hirsch, J. I., Sundaresan, G., Williamson, J., Zweit, J. & Pugachev, A., Oct 1 2012, In : Radiotherapy and Oncology. 105, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

WE‐E‐108‐11: PET‐Guided Selective Dose Escalation for a Small Animal Tumor Model

Bass, C., Axente, M., he, J., Gobalakrishnan, S., Zweit, J., Hugo, G. & Pugachev, A., Jan 1 2013, In : Medical Physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

Conference article

Computer-assisted selection of importance factors in inverse planning

Xing, L., Li, J. G., Pugachev, A., Le, Q. T. & Boyer, A. L., Dec 1 2000, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 4, p. 3082-3085 4 p.

Research output: Contribution to journalConference article

Role of non-coplanar beams in IMRT

Pugachev, A., Li, J. G., Boyer, A. L. & Xing, L., Dec 1 2000, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1, p. 456-459 4 p.

Research output: Contribution to journalConference article

Letter

On autoradiographic studies comparing the distributions of 18F- and 14C-labeled compounds in tumor tissue specimens

Pugachev, A., Axente, M. & Humm, J., Dec 1 2010, In : Radiotherapy and Oncology. 97, 3, 1 p.

Research output: Contribution to journalLetter

2 Scopus citations
Review article

Classification and evaluation strategies of auto-segmentation approaches for PET: Report of AAPM task group No. 211

Hatt, M., Lee, J. A., Schmidtlein, C. R., El Naqa, I., Caldwell, C., De Bernardi, E., Lu, W., Das, S., Geets, X., Gregoire, V., Jeraj, R., MacManus, M. P., Mawlawi, O. R., Nestle, U., Pugachev, A., Schöder, H., Shepherd, T., Spezi, E., Visvikis, D., Zaidi, H. & 1 others, Kirov, A. S., Jun 1 2017, In : Medical Physics. 44, 6, p. e1-e42

Research output: Contribution to journalReview article

61 Scopus citations