Research Output 1987 2019

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2000
62 Citations (Scopus)

Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers

Bantignies, F., Goodman, R. & Smolik, S. M., 2000, In : Molecular and Cellular Biology. 20, 24, p. 9317-9330 14 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Drosophila Proteins
Drosophila melanogaster
Chromatin
Proteins
130 Citations (Scopus)

Fusion of constitutive membrane traffic with the cell surface observed by evanescent wave microscopy

Toomre, D., Steyer, J. A., Keller, P., Almers, W. & Simons, K., Apr 3 2000, In : Journal of Cell Biology. 149, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

Membrane Fusion
Microscopy
Chromaffin Granules
Vesicular Stomatitis
Membranes
584 Citations (Scopus)

Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus

Bergles, D. E., Roberts, J. D. B., Somogyl, P. & Jahr, C., May 11 2000, In : Nature. 405, 6783, p. 187-191 5 p.

Research output: Contribution to journalArticle

Oligodendroglia
Synapses
Hippocampus
AMPA Receptors
Glutamate Receptors
47 Citations (Scopus)

Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB

Zhang, Q., Vo, N. & Goodman, R., Jul 2000, In : Molecular and Cellular Biology. 20, 14, p. 4970-4978 9 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Histones
Carrier Proteins
Acetylation
Retinoblastoma-Binding Protein 4
18 Citations (Scopus)

Inhibition of the human intermediate conductance Ca2+-activated K+ channel, hIK1, by volatile anesthetics

Namba, T., Ishii, T. M., Ikeda, M., Hisano, T., Itoh, T., Hirota, K., Adelman, J. & Fukuda, K., Apr 28 2000, In : European Journal of Pharmacology. 395, 2, p. 95-101 7 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Anesthetics
Large-Conductance Calcium-Activated Potassium Channels
Halothane
Enflurane
67 Citations (Scopus)

Inositol 1,4,5-triphosphate-evoked responses in midbrain dopamine neurons.

Morikawa, H., Imani, F., Khodakhah, K. & Williams, J., 2000, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 20, 20

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Inositol 1,4,5-Trisphosphate
Dopaminergic Neurons
Mesencephalon
Ruthenium Red
5 Citations (Scopus)

Integrity of tritiated orphanin FQ/Nociceptin: Implications for establishing a reliable binding assay

Quigley, D. I., Arttamangkul, S., Allen, R. G. & Grandy, D., Jul 2000, In : Peptides. 21, 7, p. 1111-1118 8 p.

Research output: Contribution to journalArticle

Assays
Ligands
Peptides
COS Cells
High performance liquid chromatography
82 Citations (Scopus)

Light evokes Ca2+ spikes in the axon terminal of a retinal bipolar cell

Protti, D. A., Flores-Herr, N. & Von Gersdorff, H., Jan 2000, In : Neuron. 25, 1, p. 215-227 13 p.

Research output: Contribution to journalArticle

Retinal Bipolar Cells
Presynaptic Terminals
Light
Retina
Excitatory Amino Acid Agonists
178 Citations (Scopus)

Mice deficient in Six5 develop cataracts: Implications for myotonic dystrophy

Klesert, T. R., Cho, D. H., Clark, J. I., Maylie, J., Adelman, J., Snider, L., Yuen, E. C., Soriano, P. & Tapscott, S. J., May 2000, In : Nature Genetics. 25, 1, p. 105-109 5 p.

Research output: Contribution to journalArticle

Myotonic Dystrophy
Cataract
Myotonia
Skeletal Muscle
Galactosidases
130 Citations (Scopus)

Neuronal calcium activates a Rap1 and B-Raf signaling pathway via the cyclic adenosine monophosphate-dependent protein kinase

Grewal, S. S., Horgan, A., York, R. D., Withers, G. S., Banker, G. & Stork, P., Feb 4 2000, In : Journal of Biological Chemistry. 275, 5, p. 3722-3728 7 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Depolarization
Calcium
Extracellular Signal-Regulated MAP Kinases
PC12 Cells
137 Citations (Scopus)

Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation

Cardinaux, J. R., Notis, J. C., Zhang, Q., Vo, N., Craig, J. C., Fass, D. M., Brennan, R. G. & Goodman, R., Mar 2000, In : Molecular and Cellular Biology. 20, 5, p. 1546-1552 7 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Transcriptional Activation
Sterols
Phosphorylation
Carrier Proteins
68 Citations (Scopus)

Regulation of central synaptic transmission by 5-HT(1B) auto- and Heteroreceptors

Morikawa, H., Manzoni, O. J., Crabbe, J. J. & Williams, J., 2000, In : Molecular Pharmacology. 58, 6, p. 1271-1278 8 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT1B
Autoreceptors
Synaptic Transmission
Serotonin
Inhibitory Postsynaptic Potentials
135 Citations (Scopus)

Respiration and parturition affected by conditional overexpression of the Ca2+-activated K+ channel subunit, SK3

Bond, C. T., Sprengel, R., Bissonnette, J. M., Kaufmann, W. A., Pribnow, D., Neelands, T., Storck, T., Baetscher, M., Jerecic, J., Maylie, J., Knaus, H. G., Seeburg, P. H. & Adelman, J., Sep 15 2000, In : Science. 289, 5486, p. 1942-1946 5 p.

Research output: Contribution to journalArticle

Small-Conductance Calcium-Activated Potassium Channels
Switch Genes
Calcium-Activated Potassium Channels
Uterine Contraction
Sudden Infant Death
55 Citations (Scopus)

Rhythmic opening and closing of vesicles during constitutive exo- and endocytosis in chromaffin cells

Henkel, A. W., Meiri, H., Horstmann, H., Lindau, M. & Almers, W., Jan 4 2000, In : EMBO Journal. 19, 1, p. 84-93 10 p.

Research output: Contribution to journalArticle

Chromaffin Cells
Staurosporine
Exocytosis
Endocytosis
Electric Capacitance
183 Citations (Scopus)

Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells

Lang, T., Wacker, I., Wunderlich, I., Rohrbach, A., Giese, G., Soldati, T. & Almers, W., Jun 2000, In : Biophysical Journal. 78, 6, p. 2863-2877 15 p.

Research output: Contribution to journalArticle

Secretory Vesicles
Actins
Green Fluorescent Proteins
Adenylyl Imidodiphosphate
Phalloidine
194 Citations (Scopus)

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1

York, R. D., Molliver, D. C., Grewal, S. S., Stenberg, P. E., McCleskey, E. W. & Stork, P., 2000, In : Molecular and Cellular Biology. 20, 21, p. 8069-8083 15 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Extracellular Signal-Regulated MAP Kinases
Nerve Growth Factor
Endocytosis
PC12 Cells
38 Citations (Scopus)

Selective inhibition by adenosine of mGluR IPSPs in dopamine neurons after cocaine treatment

Fiorillo, C. D. & Williams, J., 2000, In : Journal of Neurophysiology. 83, 3, p. 1307-1314 8 p.

Research output: Contribution to journalArticle

Inhibitory Postsynaptic Potentials
Metabotropic Glutamate Receptors
Dopaminergic Neurons
Cocaine
Adenosine
41 Citations (Scopus)

SK2 encodes the apamin-sensitive Ca2+-activated K+ channels in the human leukemic T cell line, Jurkat

Jäger, H., Adelman, J. & Grissmer, S., Mar 10 2000, In : FEBS Letters. 469, 2-3, p. 196-202 7 p.

Research output: Contribution to journalArticle

Apamin
Calcium-Activated Potassium Channels
T-cells
T-Lymphocytes
Cell Line
133 Citations (Scopus)

Slow desensitization regulates the availability of synaptic GABA(A) receptors

Overstreet, L. S., Jones, M. V. & Westbrook, G., Nov 1 2000, In : Journal of Neuroscience. 20, 21, p. 7914-7921 8 p.

Research output: Contribution to journalArticle

GABA-A Receptors
gamma-Aminobutyric Acid
GABA Plasma Membrane Transport Proteins
Presynaptic Receptors
Synapses
61 Citations (Scopus)

Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: Role of the phosphotyrosine phosphatase SHP-2

Florio, T., Thellung, S., Arena, S., Corsaro, A., Bajetto, A., Schettini, G. & Stork, P., 2000, In : Journal of Physiology Paris. 94, 3-4, p. 239-250 12 p.

Research output: Contribution to journalArticle

Protein Tyrosine Phosphatases
Mitogen-Activated Protein Kinases
Somatostatin
Cell Proliferation
Non-Receptor Type 11 Protein Tyrosine Phosphatase
112 Citations (Scopus)

Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation

Diamond, J. S. & Jahr, C., 2000, In : Journal of Neurophysiology. 83, 5, p. 2835-2843 9 p.

Research output: Contribution to journalArticle

Synaptic Transmission
Astrocytes
Synapses
Amino Acid Transport System X-AG
Glutamic Acid
1 Citation (Scopus)

The murine Bis1 seizure gene and the Kcnab2 gene encoding the β2- subunit of the K+ channel are different

Zerr, P., Martin, B. & Adelman, J., 2000, In : Neurogenetics. 2, 4, p. 231-234 4 p.

Research output: Contribution to journalArticle

Seizures
Chromosomes, Human, Pair 4
DNA Sequence Analysis
Genes
Nucleotides
75 Citations (Scopus)

The N-terminal domain of p73 interacts with the CH1 domain of p300/CREB binding protein and mediates transcriptional activation and apoptosis

Zeng, X., Li, X., Miller, A., Yuan, Z., Yuan, W., Kwok, R. P. S., Goodman, R. & Lu, H., Feb 2000, In : Molecular and Cellular Biology. 20, 4, p. 1299-1310 12 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Transcriptional Activation
Apoptosis
Amino Acids
Small Cell Lung Carcinoma
118 Citations (Scopus)

The structure of a CREB bZIP·somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding

Schumacher, M. A., Goodman, R. & Brennan, R. G., Nov 10 2000, In : Journal of Biological Chemistry. 275, 45, p. 35242-35247 6 p.

Research output: Contribution to journalArticle

Dimerization
Divalent Cations
Carrier Proteins
Response Elements
Somatostatin
343 Citations (Scopus)

Transport, capture and exocytosis of single synaptic vesicles at active zones

Zenlsek, D., Steyer, J. A. & Almers, W., Aug 24 2000, In : Nature. 406, 6798, p. 849-854 6 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Exocytosis
SNARE Proteins
Cell Membrane
Presynaptic Terminals
149 Citations (Scopus)
Monomeric GTP-Binding Proteins
Protein-Serine-Threonine Kinases
Extracellular Signal-Regulated MAP Kinases
Isoproterenol
Adrenergic Receptors
1999
13 Citations (Scopus)

An alternative HER-2/neu transcript of 8 kb has an extended 3'UTR and displays increased stability in SKOV-3 ovarian carcinoma cells

Doherty, J. K., Bond, C. T., Hua, W., Adelman, J. & Clinton, G. M., Sep 1999, In : Gynecologic Oncology. 74, 3, p. 408-415 8 p.

Research output: Contribution to journalArticle

3' Untranslated Regions
erbB-2 Genes
Carcinoma
Ovarian Neoplasms
Polymerase Chain Reaction
130 Citations (Scopus)

Bicuculline block of small-conductance calcium-activated potassium channels

Khawaled, R., Bruening-Wright, A., Adelman, J. & Maylie, J., 1999, In : Pflugers Archiv European Journal of Physiology. 438, 3, p. 314-321 8 p.

Research output: Contribution to journalArticle

Small-Conductance Calcium-Activated Potassium Channels
Bicuculline
Apamin
Synapses
Aminobutyrates
263 Citations (Scopus)

Clearance of glutamate inside the synapse and beyond

Bergles, D. E., Diamond, J. S. & Jahr, C., Jun 1999, In : Current Opinion in Neurobiology. 9, 3, p. 293-298 6 p.

Research output: Contribution to journalArticle

Synapses
Glutamic Acid
Neuronal Plasticity
Exocytosis
Photons
6 Citations (Scopus)

Developmental changes that regulate the activity of locus coeruleus neurons

Maubecin, V. A. & Williams, J., Jun 1999, In : Tokai Journal of Experimental and Clinical Medicine. 24, 2, p. 41-51 11 p.

Research output: Contribution to journalArticle

Embryonic and Fetal Development
Locus Coeruleus
Synaptic Transmission
Synapses
Action Potentials
182 Citations (Scopus)

Domains responsible for constitutive and Ca2+-dependent interactions between calmodulin and small conductance Ca2+-activated potassium channels

Keen, J. E., Khawaled, R., Farrens, D., Neelands, T., Rivard, A., Bond, C. T., Janowsky, A., Fakler, B., Adelman, J. & Maylie, J., Oct 15 1999, In : Journal of Neuroscience. 19, 20, p. 8830-8838 9 p.

Research output: Contribution to journalArticle

Potassium Channels
Calmodulin
Small-Conductance Calcium-Activated Potassium Channels
Ion Channel Gating
Hand
14 Citations (Scopus)

Dream on without calcium

Mandel, G. & Goodman, R., Mar 4 1999, In : Nature. 398, 6722, p. 29-30 2 p.

Research output: Contribution to journalArticle

Kv Channel-Interacting Proteins
Repressor Proteins
Cyclic AMP Response Element-Binding Protein
Calcium-Binding Proteins
Protein Precursors
84 Citations (Scopus)

Electrophysiology of synaptic vesicle cycling

Von Gersdorff, H. & Matthews, G., 1999, In : Annual Review of Physiology. 61, p. 725-752 28 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Electrophysiology
Presynaptic Terminals
Synaptic Membranes
Goldfish
91 Citations (Scopus)

Elevation of cyclic adenosine 3',5'-monophosphate potentiates activation of mitogen-activated protein kinase by growth factors in LNCaP prostate cancer cells

Chen, T., Cho, R. W., Stork, P. & Weber, M. J., Jan 1 1999, In : Cancer Research. 59, 1, p. 213-218 6 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Cyclic AMP
Prostatic Neoplasms
Intercellular Signaling Peptides and Proteins
Epidermal Growth Factor
255 Citations (Scopus)

Endocytic vesicles move at the tips of actin tails in cultured mast cells

Merrifield, C. J., Moss, S. E., Ballestrem, C., Imhof, B. A., Giese, G., Wunderlich, I. & Almers, W., May 1999, In : Nature Cell Biology. 1, 1, p. 72-74 3 p.

Research output: Contribution to journalArticle

Recombinant Fusion Proteins
Transport Vesicles
Endosomes
Endocytosis
Mast Cells
474 Citations (Scopus)

Extracellular-signal-regulated kinase signalling in neurons

Grewal, S. S., York, R. D. & Stork, P., Oct 1 1999, In : Current Opinion in Neurobiology. 9, 5, p. 544-553 10 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Neurons
Neuronal Plasticity
Monomeric GTP-Binding Proteins
Long-Term Potentiation
80 Citations (Scopus)
Extracellular Signal-Regulated MAP Kinases
Atrial Natriuretic Factor
Protein Kinases
Muscle Cells
Rats
46 Citations (Scopus)

Gating properties of single SK channels in hippocampal CA1 pyramidal neurons

Hirschberg, B., Maylie, J., Adelman, J. & Marrion, N. V., Oct 1999, In : Biophysical Journal. 77, 4, p. 1905-1913 9 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Small-Conductance Calcium-Activated Potassium Channels
Neurons
Action Potentials
Membranes
15 Citations (Scopus)

Gene structure and chromosome mapping of the human small-conductance calcium-activated potassium channel SK1 gene (KCNN1)

Litt, M., LaMorticella, D., Bond, C. T. & Adelman, J., 1999, In : Cytogenetics and Cell Genetics. 86, 1, p. 70-73 4 p.

Research output: Contribution to journalArticle

Small-Conductance Calcium-Activated Potassium Channels
Chromosome Mapping
Radiation Hybrid Mapping
Genes
Complementary DNA
234 Citations (Scopus)

Interactions of calmodulin and α-actinin with the NR1 subunit modulate Ca2+-dependent inactivation of NMDA receptors

Krupp, J. J., Vissel, B., Thomas, C. G., Heinemann, S. F. & Westbrook, G., Feb 15 1999, In : Journal of Neuroscience. 19, 4, p. 1165-1178 14 p.

Research output: Contribution to journalArticle

Actinin
Calmodulin
Carbon Monoxide
N-Methyl-D-Aspartate Receptors
Calcium
17 Citations (Scopus)

Mapping of the human Voltage-Dependent Anion Channel isoforms 1 and 2 reconsidered

Messina, A., Oliva, M., Rosato, C., Huizing, M., Ruitenbeek, W., Van Den Heuvel, L. P., Forte, M., Rocchi, M. & De Pinto, V., Feb 24 1999, In : Biochemical and Biophysical Research Communications. 255, 3, p. 707-710 4 p.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channel 2
Voltage-Dependent Anion Channels
Chromosomes
Protein Isoforms
Genes
115 Citations (Scopus)
Mitogen-Activated Protein Kinase Phosphatases
Dual Specificity Phosphatase 1
Tumor Microenvironment
JNK Mitogen-Activated Protein Kinases
Heat-Shock Proteins
131 Citations (Scopus)

Modulation of Rap activity by direct interaction of Gα(o) with rap1 GTPase-activating protein

Jordan, J. D., Carey, K. D., Stork, P. & Iyengar, R., Jul 30 1999, In : Journal of Biological Chemistry. 274, 31, p. 21507-21510 4 p.

Research output: Contribution to journalArticle

GTPase-Activating Proteins
Modulation
Chemical activation
RGS Proteins
Two-Hybrid System Techniques
56 Citations (Scopus)

Modulation of the light response by cAMP in Drosophila photoreceptors

Chyb, S., Hevers, W., Forte, M., Wolfgang, W. J., Selinger, Z. & Hardie, R. C., Oct 15 1999, In : Journal of Neuroscience. 19, 20, p. 8799-8807 9 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Adenylyl Cyclases
Light Signal Transduction
Drosophila
1-Methyl-3-isobutylxanthine
77 Citations (Scopus)

Mutants of cubitus interruptus that are independent of PKA regulation are independent of hedgehog signaling

Chen, Y., Cardinaux, J. R., Goodman, R. & Smolik, S. M., Aug 1999, In : Development. 126, 16, p. 3607-3616 10 p.

Research output: Contribution to journalArticle

Hedgehogs
Embryonic Development
Phosphorylation
Phenotype
Gene Expression
3 Citations (Scopus)

Mutations in the voltage-dependent anion channel of the mitochondrial outer membrane cause a dominant nonlethal growth impairment

Angeles, R., Devine, J., Barret, R., Goebel, D., Blachyl-Dyson, E., Forte, M. & McCauley, R., 1999, In : Journal of Bioenergetics and Biomembranes. 31, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channels
Mitochondrial Membranes
Mutation
Growth
Lysine
55 Citations (Scopus)

Presynaptic inhibition of GABA(B)-mediated synaptic potentials in the ventral tegmental area during morphine withdrawal

Shoji, Y., Delfs, J. & Williams, J., Mar 15 1999, In : Journal of Neuroscience. 19, 6, p. 2347-2355 9 p.

Research output: Contribution to journalArticle

Synaptic Potentials
Ventral Tegmental Area
Inhibitory Postsynaptic Potentials
gamma-Aminobutyric Acid
Morphine
119 Citations (Scopus)

Presynaptic regulation of glutamate release in the ventral tegmental area during morphine withdrawal

Manzoni, O. J. & Williams, J., Aug 1 1999, In : Journal of Neuroscience. 19, 15, p. 6629-6636 8 p.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Morphine
Opioid Analgesics
Glutamic Acid
Dopamine
169 Citations (Scopus)

Regulation of synaptic timing in the olfactory bulb by an A-type potassium current

Schoppa, N. E. & Westbrook, G., Dec 1999, In : Nature Neuroscience. 2, 12, p. 1106-1113 8 p.

Research output: Contribution to journalArticle

Olfactory Bulb
Potassium
AMPA Receptors
N-Methyl-D-Aspartate Receptors
Synaptic Transmission
33 Citations (Scopus)

Skeletal muscle and small-conductance calcium-activated potassium channels

Pribnow, D., Johnson-Pais, T., Bond, C. T., Keen, J., Johnson, R. A., Janowsky, A., Silvia, C., Thayer, M. M., Maylie, J. & Adelman, J., Jun 1999, In : Muscle and Nerve. 22, 6, p. 742-750 9 p.

Research output: Contribution to journalArticle

Small-Conductance Calcium-Activated Potassium Channels
Apamin
Skeletal Muscle
Binding Sites
Skeletal Muscle Fibers