Wide-field sensorless adaptive optics swept-source optical coherence tomographic angiography in rodents

Xiang Wei; Tristan T. Hormel; Shaohua Pi; Bingjie Wang; John C. Morrison; Yali Jia

doi:10.1364/OL.472387

Wide-field sensorless adaptive optics swept-source optical coherence tomographic angiography in rodents

Xiang Wei, Tristan T. Hormel, Shaohua Pi, Bingjie Wang, John C. Morrison, Yali Jia

Ophthalmology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In this study, we present a sensorless adaptive optics swept-source optical coherence tomographic angiography (sAO-SS-OCTA) imaging system for mice. Real-time graphics processing unit (GPU)-based OCTA image acquisition and processing software were applied to guide wavefront correction using a deformable mirror based on signal strength index (SSI) from both OCT and OCTA images. High-resolution OCTA images with aberrations corrected and contrast enhanced were successfully acquired. Fifty-degree field of view high-resolution montaged OCTA images were also acquired.

Original language	English (US)
Pages (from-to)	5060-5063
Number of pages	4
Journal	Optics Letters
Volume	47
Issue number	19
DOIs	https://doi.org/10.1364/OL.472387
State	Published - Oct 1 2022

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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abstract = "In this study, we present a sensorless adaptive optics swept-source optical coherence tomographic angiography (sAO-SS-OCTA) imaging system for mice. Real-time graphics processing unit (GPU)-based OCTA image acquisition and processing software were applied to guide wavefront correction using a deformable mirror based on signal strength index (SSI) from both OCT and OCTA images. High-resolution OCTA images with aberrations corrected and contrast enhanced were successfully acquired. Fifty-degree field of view high-resolution montaged OCTA images were also acquired.",

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AU - Wei, Xiang

AU - Hormel, Tristan T.

AU - Pi, Shaohua

AU - Wang, Bingjie

AU - Morrison, John C.

AU - Jia, Yali

PY - 2022/10/1

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N2 - In this study, we present a sensorless adaptive optics swept-source optical coherence tomographic angiography (sAO-SS-OCTA) imaging system for mice. Real-time graphics processing unit (GPU)-based OCTA image acquisition and processing software were applied to guide wavefront correction using a deformable mirror based on signal strength index (SSI) from both OCT and OCTA images. High-resolution OCTA images with aberrations corrected and contrast enhanced were successfully acquired. Fifty-degree field of view high-resolution montaged OCTA images were also acquired.

AB - In this study, we present a sensorless adaptive optics swept-source optical coherence tomographic angiography (sAO-SS-OCTA) imaging system for mice. Real-time graphics processing unit (GPU)-based OCTA image acquisition and processing software were applied to guide wavefront correction using a deformable mirror based on signal strength index (SSI) from both OCT and OCTA images. High-resolution OCTA images with aberrations corrected and contrast enhanced were successfully acquired. Fifty-degree field of view high-resolution montaged OCTA images were also acquired.

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Wide-field sensorless adaptive optics swept-source optical coherence tomographic angiography in rodents

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