TY - JOUR
T1 - What is the best measure of maternal complications of term pregnancy
T2 - Ongoing pregnancies or pregnancies delivered?
AU - Caughey, Aaron B.
AU - Stotland, Naomi E.
AU - Escobar, Gabriel J.
N1 - Funding Information:
A. B. C. is a Women's Reproductive Health Research Scholar, sponsored by the National Institute of Child Health and Human Development, grant No. HD01262.
PY - 2003/10
Y1 - 2003/10
N2 - OBJECTIVE: The purpose of this study was to determine whether rates of hypertensive disorders of pregnancy increase beyond 37 weeks of gestation and to address how best to analyze these rates. STUDY DESIGN: This was a retrospective cohort study of all women delivered beyond 37 weeks' gestational age from 1995 to 1999 at all Kaiser Permanente Medical Care Program delivery hospitals in Northern California. Rates of gestational hypertension, preeclampsia, and eclampsia were calculated by use of both pregnancy delivered (PD) and ongoing pregnancy (OP) as the denominator. Bivariate and multivariate analyses were conducted with use of P < .05 to indicate statistical significance. RESULTS: Among the 135,560 women in this cohort, the rates of gestational hypertension, preeclampsia, and eclampsia were the same or decreased from 37 to 43 weeks' gestation using PD, but all three increased when calculated according to OP (P < .01). CONCLUSION: We found that among complications of pregnancy that are diagnosed ante partum, use of a different denominator led to contradictory conclusions. When hypertensive disorders of pregnancy are analyzed, ongoing pregnancies should be used as the denominator.
AB - OBJECTIVE: The purpose of this study was to determine whether rates of hypertensive disorders of pregnancy increase beyond 37 weeks of gestation and to address how best to analyze these rates. STUDY DESIGN: This was a retrospective cohort study of all women delivered beyond 37 weeks' gestational age from 1995 to 1999 at all Kaiser Permanente Medical Care Program delivery hospitals in Northern California. Rates of gestational hypertension, preeclampsia, and eclampsia were calculated by use of both pregnancy delivered (PD) and ongoing pregnancy (OP) as the denominator. Bivariate and multivariate analyses were conducted with use of P < .05 to indicate statistical significance. RESULTS: Among the 135,560 women in this cohort, the rates of gestational hypertension, preeclampsia, and eclampsia were the same or decreased from 37 to 43 weeks' gestation using PD, but all three increased when calculated according to OP (P < .01). CONCLUSION: We found that among complications of pregnancy that are diagnosed ante partum, use of a different denominator led to contradictory conclusions. When hypertensive disorders of pregnancy are analyzed, ongoing pregnancies should be used as the denominator.
KW - Hypertensive disorders of pregnancy
KW - Maternal complications of pregnancy
KW - Perinatal epidemiology
KW - Preeclampsia
UR - http://www.scopus.com/inward/record.url?scp=0242509124&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0242509124&partnerID=8YFLogxK
U2 - 10.1067/S0002-9378(03)00897-4
DO - 10.1067/S0002-9378(03)00897-4
M3 - Article
C2 - 14586353
AN - SCOPUS:0242509124
SN - 0002-9378
VL - 189
SP - 1047
EP - 1052
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 4
ER -