Weekly observations of online survey metadata obtained through home computer use allow for detection of changes in everyday cognition before transition to mild cognitive impairment

Adriana Seelye, Nora Mattek, Nicole Sharma, Thomas Riley, Johanna Austin, Katherine Wild, Hiroko Dodge, Emily Lore, Jeffrey Kaye

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Subtle changes in instrumental activities of daily living often accompany the onset of mild cognitive impairment (MCI) but are difficult to measure using conventional tests. Methods: Weekly online survey metadata metrics, annual neuropsychological tests, and an instrumental activity of daily living questionnaire were examined in 110 healthy older adults with intact cognition (mean age = 85 years) followed up for up to 3.6 years; 29 transitioned to MCI during study follow-up. Results: In the baseline period, incident MCI participants completed their weekly surveys 1.4 hours later in the day than stable cognitively intact participants, P = .03, d = 0.47. Significant associations were found between earlier survey start time of day and higher memory (r = -0.34; P < .001) and visuospatial test scores (r = -0.37; P < .0001). Longitudinally, incident MCI participants showed an increase in survey completion time by 3 seconds per month for more than the year before diagnosis compared with stable cognitively intact participants (β = 0.12, SE = 0.04, t = 2.8; P = .006). Discussion: Weekly online survey metadata allowed for detection of changes in everyday cognition before transition to MCI.

Original languageEnglish (US)
JournalAlzheimer's and Dementia
DOIs
StateAccepted/In press - 2017

Fingerprint

Cognition
Activities of Daily Living
Neuropsychological Tests
Metadata
Cognitive Dysfunction
Surveys and Questionnaires

Keywords

  • Activity monitoring
  • Aging
  • Computer use
  • Ecological validity
  • Everyday cognition
  • In-home technology
  • Longitudinal
  • Older adults
  • Preclinical AD

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Developmental Neuroscience
  • Clinical Neurology
  • Geriatrics and Gerontology
  • Cellular and Molecular Neuroscience
  • Psychiatry and Mental health

Cite this

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title = "Weekly observations of online survey metadata obtained through home computer use allow for detection of changes in everyday cognition before transition to mild cognitive impairment",
abstract = "Introduction: Subtle changes in instrumental activities of daily living often accompany the onset of mild cognitive impairment (MCI) but are difficult to measure using conventional tests. Methods: Weekly online survey metadata metrics, annual neuropsychological tests, and an instrumental activity of daily living questionnaire were examined in 110 healthy older adults with intact cognition (mean age = 85 years) followed up for up to 3.6 years; 29 transitioned to MCI during study follow-up. Results: In the baseline period, incident MCI participants completed their weekly surveys 1.4 hours later in the day than stable cognitively intact participants, P = .03, d = 0.47. Significant associations were found between earlier survey start time of day and higher memory (r = -0.34; P < .001) and visuospatial test scores (r = -0.37; P < .0001). Longitudinally, incident MCI participants showed an increase in survey completion time by 3 seconds per month for more than the year before diagnosis compared with stable cognitively intact participants (β = 0.12, SE = 0.04, t = 2.8; P = .006). Discussion: Weekly online survey metadata allowed for detection of changes in everyday cognition before transition to MCI.",
keywords = "Activity monitoring, Aging, Computer use, Ecological validity, Everyday cognition, In-home technology, Longitudinal, Older adults, Preclinical AD",
author = "Adriana Seelye and Nora Mattek and Nicole Sharma and Thomas Riley and Johanna Austin and Katherine Wild and Hiroko Dodge and Emily Lore and Jeffrey Kaye",
year = "2017",
doi = "10.1016/j.jalz.2017.07.756",
language = "English (US)",
journal = "Alzheimer's and Dementia",
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T1 - Weekly observations of online survey metadata obtained through home computer use allow for detection of changes in everyday cognition before transition to mild cognitive impairment

AU - Seelye, Adriana

AU - Mattek, Nora

AU - Sharma, Nicole

AU - Riley, Thomas

AU - Austin, Johanna

AU - Wild, Katherine

AU - Dodge, Hiroko

AU - Lore, Emily

AU - Kaye, Jeffrey

PY - 2017

Y1 - 2017

N2 - Introduction: Subtle changes in instrumental activities of daily living often accompany the onset of mild cognitive impairment (MCI) but are difficult to measure using conventional tests. Methods: Weekly online survey metadata metrics, annual neuropsychological tests, and an instrumental activity of daily living questionnaire were examined in 110 healthy older adults with intact cognition (mean age = 85 years) followed up for up to 3.6 years; 29 transitioned to MCI during study follow-up. Results: In the baseline period, incident MCI participants completed their weekly surveys 1.4 hours later in the day than stable cognitively intact participants, P = .03, d = 0.47. Significant associations were found between earlier survey start time of day and higher memory (r = -0.34; P < .001) and visuospatial test scores (r = -0.37; P < .0001). Longitudinally, incident MCI participants showed an increase in survey completion time by 3 seconds per month for more than the year before diagnosis compared with stable cognitively intact participants (β = 0.12, SE = 0.04, t = 2.8; P = .006). Discussion: Weekly online survey metadata allowed for detection of changes in everyday cognition before transition to MCI.

AB - Introduction: Subtle changes in instrumental activities of daily living often accompany the onset of mild cognitive impairment (MCI) but are difficult to measure using conventional tests. Methods: Weekly online survey metadata metrics, annual neuropsychological tests, and an instrumental activity of daily living questionnaire were examined in 110 healthy older adults with intact cognition (mean age = 85 years) followed up for up to 3.6 years; 29 transitioned to MCI during study follow-up. Results: In the baseline period, incident MCI participants completed their weekly surveys 1.4 hours later in the day than stable cognitively intact participants, P = .03, d = 0.47. Significant associations were found between earlier survey start time of day and higher memory (r = -0.34; P < .001) and visuospatial test scores (r = -0.37; P < .0001). Longitudinally, incident MCI participants showed an increase in survey completion time by 3 seconds per month for more than the year before diagnosis compared with stable cognitively intact participants (β = 0.12, SE = 0.04, t = 2.8; P = .006). Discussion: Weekly online survey metadata allowed for detection of changes in everyday cognition before transition to MCI.

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KW - Older adults

KW - Preclinical AD

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