A possible link between insufficient sleep and metabolism dysregulation has been suggested by studies showing that a prolonged sleep curtailment may act as a key co-factor for the development of obesity and/or metabolic syndrome . Sleep restriction protocols have been shown to reduce glucose tolerance and insulin sensitivity and to reduce the leptin/ghrelin ratio, possibly leading subjects to eat more than needed . These data have been partly confirmed by the results of a recent study, showing that sleep restriction induced an increase in energy expenditure which was overcompensated by an increase in energy intake leading to weight gain, in spite of a concomitant increase in the leptin/ghrelin ratio .
|Original language||English (US)|
|Title of host publication||Sleep, Circadian Rhythms, and Metabolism|
|Subtitle of host publication||The Rhythm of Life|
|Publisher||Apple Academic Press|
|Number of pages||20|
|State||Published - Jan 1 2014|
ASJC Scopus subject areas