@article{3c66459aa73240e5a8815ae4e9e7b4ea,
title = "Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques",
abstract = "Aid et al. show that SARS-CoV-2 causes endothelial disruption and vascular thrombosis in both human and rhesus macaques lungs by inducing an upregulation of proinflammatory cytokines. Using an approach that combines histopathology and multiomics in macaques, they show the progression to vascular disease over time, which involves complement, macrophage, cytokine, and thrombosis cascades.",
keywords = "IFNα, SARS-CoV-2, coagulation, collagen, complement, macrophage, platelet, thrombosis, vWF, vascular",
author = "Malika Aid and Kathleen Busman-Sahay and Vidal, {Samuel J.} and Zoltan Maliga and Stephen Bondoc and Carly Starke and Margaret Terry and Jacobson, {Connor A.} and Linda Wrijil and Sarah Ducat and Brook, {Olga R.} and Miller, {Andrew D.} and Maciel Porto and Pellegrini, {Kathryn L.} and Maria Pino and Hoang, {Timothy N.} and Abishek Chandrashekar and Shivani Patel and Kathryn Stephenson and Bosinger, {Steven E.} and Hanne Andersen and Lewis, {Mark G.} and Hecht, {Jonathan L.} and Sorger, {Peter K.} and Martinot, {Amanda J.} and Estes, {Jacob D.} and Barouch, {Dan H.}",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = nov,
day = "25",
doi = "10.1016/j.cell.2020.10.005",
language = "English (US)",
volume = "183",
pages = "1354--1366.e13",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "5",
}