Variation in small bowel biopsy performance among diverse endoscopy settings: Results from a national endoscopic database

Gavin C. Harewood, Jennifer L. Holub, David Lieberman

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

BACKGROUND: The diagnostic gold standard for celiac sprue requires performance of small bowel biopsy to identify characteristic mucosal changes. The current biopsy practice among endoscopists for celiac sprue is unknown. METHODS: The CORI (Clinical Outcomes Research Initiative) national endoscopic database was analyzed to determine the rate of small bowel biopsy in patients undergoing EGD for the evaluation of anemia, iron deficiency without anemia, weight loss, and diarrhea. RESULTS: Between January 2000 and September 2003, 3,992 patients underwent EGD for the evaluation of anemia, iron deficiency, weight loss, and diarrhea with normal EGD findings. Overall, 438 patients (11%) underwent small bowel biopsy. Small bowel biopsy performance varied with procedure indication: anemia 10%, iron deficiency 7%, weight loss 6%, and diarrhea 19%, p <0.0001. Biopsy rates declined with advancing patient age; 12% (

Original languageEnglish (US)
Pages (from-to)1790-1794
Number of pages5
JournalAmerican Journal of Gastroenterology
Volume99
Issue number9
DOIs
StatePublished - Sep 2004
Externally publishedYes

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Endoscopy
Databases
Biopsy
Iron-Deficiency Anemias
Weight Loss
Diarrhea
Celiac Disease
Anemia
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Variation in small bowel biopsy performance among diverse endoscopy settings : Results from a national endoscopic database. / Harewood, Gavin C.; Holub, Jennifer L.; Lieberman, David.

In: American Journal of Gastroenterology, Vol. 99, No. 9, 09.2004, p. 1790-1794.

Research output: Contribution to journalArticle

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