Uterine oxygen uptake in the pregnant pygmy goat

John M. Bissonnette, James Metcalfe, A. Roger Hohimer, Martin L. Pernoll, J. Eugen Welch, Maralee S. Lawson

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The diffusion equilibrium method was used to measure uterine blood flow (Q̇ut) and oxygen consumption (V̇utO2) of 7 Pygmy goats in the last third of pregnancy. V̇utO2 was 9.3 ± 1.3 (mean ± SEM) ml · min-1 · kg-1 weight of the uterus and its contents: the placenta, fetus and fetal membranes. This O2 requirement was provided by a high blood flow (349 ± 48 ml · min-1 · kg-1) and a narrow arteriovenous difference (2.4 ± 0.1 vol %) across the uterus. Maternal arterial O2 content (CaO2 ) was varied by incurring chronic anemia in 3 animals. CaO2 over the range 6.5-12.8 vol % did not affect uterine blood flow or the arteriovenous oxygen content difference across the uterus. Weight specific (ml · min-1 · kg-1) V̇utO2 did not differ in animals whose total uterine weights varied over a wide range and uterine vein oxygen tension and content did not fall prior to delivery. We conclude that the absolute uterine blood flow varies over a wide range to meet the requirements of the uterine contents.

Original languageEnglish (US)
Pages (from-to)373-381
Number of pages9
JournalRespiration Physiology
Volume42
Issue number3
DOIs
StatePublished - Dec 1980

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Keywords

  • Anemia
  • Fetus
  • Oxygen consumption
  • Placenta
  • Pregnancy
  • Uterine blood flow

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine

Cite this

Bissonnette, J. M., Metcalfe, J., Hohimer, A. R., Pernoll, M. L., Welch, J. E., & Lawson, M. S. (1980). Uterine oxygen uptake in the pregnant pygmy goat. Respiration Physiology, 42(3), 373-381. https://doi.org/10.1016/0034-5687(80)90126-7