The diffusion equilibrium method was used to measure uterine blood flow (Q̇ut) and oxygen consumption (V̇utO2) of 7 Pygmy goats in the last third of pregnancy. V̇utO2 was 9.3 ± 1.3 (mean ± SEM) ml · min-1 · kg-1 weight of the uterus and its contents: the placenta, fetus and fetal membranes. This O2 requirement was provided by a high blood flow (349 ± 48 ml · min-1 · kg-1) and a narrow arteriovenous difference (2.4 ± 0.1 vol %) across the uterus. Maternal arterial O2 content (CaO2 ) was varied by incurring chronic anemia in 3 animals. CaO2 over the range 6.5-12.8 vol % did not affect uterine blood flow or the arteriovenous oxygen content difference across the uterus. Weight specific (ml · min-1 · kg-1) V̇utO2 did not differ in animals whose total uterine weights varied over a wide range and uterine vein oxygen tension and content did not fall prior to delivery. We conclude that the absolute uterine blood flow varies over a wide range to meet the requirements of the uterine contents.
- Oxygen consumption
- Uterine blood flow
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine