Usefulness of fasting and postprandial duplex ultrasound examinations for predicting high-grade superior mesenteric artery stenosis

Andrew T. Gentile, Gregory L. Moneta, Raymond W. Lee, Philippe A. Masser, Lloyd M. Taylor, John M. Porter

    Research output: Contribution to journalArticlepeer-review

    72 Scopus citations


    A fasting duplex ultrasound examination of the superior mesenteric artery (SMA) accurately detects high-grade (>70%) stenosis. It has been postulated that postprandial niesenteric duplex scanning may further stratify stenosis and improve the ability of a fasting examination to detect a high-grade stenosis. We performed fasting and postprandial duplex scanning of 25 healthy controls and 80 patients with vascular disease undergoing aortography to determine whether postprandial mesenteric duplex scanning provides information beyond a fasting study alone. Patients with vascular disease were divided into three groups based on lateral aortography results: group 1, 0% to <30% SMA stenosis (n = 61); group 2, 30% to <70% stenosis (n = 10); and group 3, 70% to 99% stenosis (n = 9). Fasting mesenteric duplex scanning was defined as positive for 70% to 99% stenosis if the peak systolic velocity (PSV) was ≥275 cm/s. The ability of either fasting or postprandial mesenteric duplex scanning, and their combination, to predict high-grade (70% to 99%) SMA stenosis was determined using angiographic control. Mean fasting SMA PSV did not differ among controls and groups 1 and 2. Postprandial PSV increased significantly in all groups, but was not different among controls and groups 1 and 2. Mean fasting PSV was significantly higher, and the postprandial increase in PSV significantly lower, in group 3 compared with controls and with groups 1 and 2. Fasting niesenteric duplex scanning predicted 70% to 99% SMA stenosis, with 89% sensitivity, 97% specificity, 80% positive predictive value, 99% negative predictive value, and 96% accuracy. Corresponding values for postprandial scanning were 67%, 94%, 60%, 96%, 91%, and for the combination of normal fasting and postprandial scanning 67%, 100%, 100%, 96%, 96%, respectively. Postprandial increases in SMA PSVs are blunted in patients with high-grade stenosis, but feeding velocities do not stratify between lesser degrees of stenosis. Both fasting and postprandial PSVs identify high-grade (>70%) stenosis. Their combination marginally improves fasting duplex scan specificity and positive predictive value. Postprandial scanning is not necessary for the diagnosis of high-grade stenosis if a fasting study identifies a PSV ≥275 cm/s. The combination of normal fasting and postprandial niesenteric duplex ultrasound scanning may effectively rule out high-grade SMA stenosis.

    Original languageEnglish (US)
    Pages (from-to)476-479
    Number of pages4
    JournalAmerican journal of surgery
    Issue number5
    StatePublished - Jan 1 1995

    ASJC Scopus subject areas

    • Surgery


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