Two-Dimensional Inverse Laplace Transform NMR: Altered Relaxation Times Allow Detection of Exchange Correlation

Jing Huei Lee; Christian Labadie; Charles S. Springer; Gerard S. Harbison; Jing Huei Lee; Christian Labadie; Charles S. Springer; Gerard S. Harbison

doi:10.1021/ja00070a022

Two-Dimensional Inverse Laplace Transform NMR: Altered Relaxation Times Allow Detection of Exchange Correlation

Jing Huei Lee, Christian Labadie, Charles S. Springer, Gerard S. Harbison, Jing Huei Lee, Christian Labadie, Charles S. Springer, Gerard S. Harbison

Research output: Contribution to journal › Article › peer-review

120 Scopus citations

Abstract

A pulse sequence for a two-dimensional inverse Laplace transform NMR experiment is proposed and demonstrated. The experiment is analogous to the two-dimensional Fourier transform protocol called EXSY, but detects exchange by monitoring alterations in the transverse relaxation time rather than the NMR frequency. The sequence may be useful for measurement of exchange and diffusion of water in vivo and for detecting slow exchange phenomena in glassy polymers.

Original language	English (US)
Pages (from-to)	7761-7764
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	115
Issue number	17
DOIs	https://doi.org/10.1021/ja00070a022
State	Published - Aug 1 1993
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja00070a022

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abstract = "A pulse sequence for a two-dimensional inverse Laplace transform NMR experiment is proposed and demonstrated. The experiment is analogous to the two-dimensional Fourier transform protocol called EXSY, but detects exchange by monitoring alterations in the transverse relaxation time rather than the NMR frequency. The sequence may be useful for measurement of exchange and diffusion of water in vivo and for detecting slow exchange phenomena in glassy polymers.",

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AU - Harbison, Gerard S.

AU - Lee, Jing Huei

AU - Labadie, Christian

AU - Springer, Charles S.

AU - Harbison, Gerard S.

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Two-Dimensional Inverse Laplace Transform NMR: Altered Relaxation Times Allow Detection of Exchange Correlation

Abstract

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