Two-Dimensional Inverse Laplace Transform NMR: Altered Relaxation Times Allow Detection of Exchange Correlation

Jing Huei Lee; Christian Labadie; Charles S. Springer; Gerard S. Harbison; Jing Huei Lee; Christian Labadie; Charles S. Springer; Gerard S. Harbison

doi:10.1021/ja00070a022

Two-Dimensional Inverse Laplace Transform NMR: Altered Relaxation Times Allow Detection of Exchange Correlation

Jing Huei Lee, Christian Labadie, Charles S. Springer, Gerard S. Harbison, Jing Huei Lee, Christian Labadie, Charles S. Springer, Gerard S. Harbison

Research output: Contribution to journal › Article › peer-review

132 Scopus citations

Abstract

A pulse sequence for a two-dimensional inverse Laplace transform NMR experiment is proposed and demonstrated. The experiment is analogous to the two-dimensional Fourier transform protocol called EXSY, but detects exchange by monitoring alterations in the transverse relaxation time rather than the NMR frequency. The sequence may be useful for measurement of exchange and diffusion of water in vivo and for detecting slow exchange phenomena in glassy polymers.

Original language	English (US)
Pages (from-to)	7761-7764
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	115
Issue number	17
DOIs	https://doi.org/10.1021/ja00070a022
State	Published - Aug 1 1993
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

Access to Document

10.1021/ja00070a022

Cite this

@article{ce7f1f4cb97b43a1a3515d37434b398d,

title = "Two-Dimensional Inverse Laplace Transform NMR: Altered Relaxation Times Allow Detection of Exchange Correlation",

abstract = "A pulse sequence for a two-dimensional inverse Laplace transform NMR experiment is proposed and demonstrated. The experiment is analogous to the two-dimensional Fourier transform protocol called EXSY, but detects exchange by monitoring alterations in the transverse relaxation time rather than the NMR frequency. The sequence may be useful for measurement of exchange and diffusion of water in vivo and for detecting slow exchange phenomena in glassy polymers.",

author = "Lee, {Jing Huei} and Christian Labadie and Springer, {Charles S.} and Harbison, {Gerard S.} and Lee, {Jing Huei} and Christian Labadie and Springer, {Charles S.} and Harbison, {Gerard S.}",

year = "1993",

month = aug,

day = "1",

doi = "10.1021/ja00070a022",

language = "English (US)",

volume = "115",

pages = "7761--7764",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

number = "17",

}

TY - JOUR

T1 - Two-Dimensional Inverse Laplace Transform NMR

T2 - Altered Relaxation Times Allow Detection of Exchange Correlation

AU - Lee, Jing Huei

AU - Labadie, Christian

AU - Springer, Charles S.

AU - Harbison, Gerard S.

AU - Lee, Jing Huei

AU - Labadie, Christian

AU - Springer, Charles S.

AU - Harbison, Gerard S.

PY - 1993/8/1

Y1 - 1993/8/1

N2 - A pulse sequence for a two-dimensional inverse Laplace transform NMR experiment is proposed and demonstrated. The experiment is analogous to the two-dimensional Fourier transform protocol called EXSY, but detects exchange by monitoring alterations in the transverse relaxation time rather than the NMR frequency. The sequence may be useful for measurement of exchange and diffusion of water in vivo and for detecting slow exchange phenomena in glassy polymers.

AB - A pulse sequence for a two-dimensional inverse Laplace transform NMR experiment is proposed and demonstrated. The experiment is analogous to the two-dimensional Fourier transform protocol called EXSY, but detects exchange by monitoring alterations in the transverse relaxation time rather than the NMR frequency. The sequence may be useful for measurement of exchange and diffusion of water in vivo and for detecting slow exchange phenomena in glassy polymers.

UR - http://www.scopus.com/inward/record.url?scp=0000827928&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0000827928&partnerID=8YFLogxK

U2 - 10.1021/ja00070a022

DO - 10.1021/ja00070a022

M3 - Article

AN - SCOPUS:0000827928

SN - 0002-7863

VL - 115

SP - 7761

EP - 7764

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 17

ER -

Two-Dimensional Inverse Laplace Transform NMR: Altered Relaxation Times Allow Detection of Exchange Correlation

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this