Trends in the prevalence of dementia in Japan

Hiroko Dodge, Teresa J. Buracchio, Gwenith G. Fisher, Yutaka Kiyohara, Kenichi Meguro, Yumihiro Tanizaki, Jeffrey Kaye

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

There is a paucity of data regarding trends in dementia and its subtype prevalence in Japan. Our aims in the current paper are to: (1) summarize epidemiological studies of dementia in Japan including relevant details of study protocol and diagnostic criteria, (2) compare the age-specific prevalence of all-cause dementia among studies, and (3) assess the trends in Alzheimer's disease (AD) versus vascular dementia (VaD) over time. We reviewed diagnostic criteria, all-cause dementia prevalence, and the AD/VaD ratio from 8 large population studies of dementia in Japan. Compared with the Okinawa 1992 study, studies conducted in 1994, 1998, 2005, and 2008 had a higher prevalence of all-cause dementia using Poisson regression models, after controlling for age and sex. In contrast to the US and some European countries, all-cause dementia prevalence is increasing in Japan. The prevalence of AD as opposed to VaD seems to be increasing over time, but large variability in diagnostic criteria, possible regional variability, and differences in prevalence of subtypes of dementia between men and women make it difficult to draw a conclusion about this trend at the national level. Further studies, for example, comparing the population attributable risk of vascular diseases to the prevalence and incidence of dementia could help to clarify the regional variations in etiological subtypes.

Original languageEnglish (US)
Article number956354
JournalInternational Journal of Alzheimer's Disease
DOIs
StatePublished - 2012

Fingerprint

Dementia
Japan
Vascular Dementia
Alzheimer Disease
Vascular Diseases
Population
Epidemiologic Studies
Incidence

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Aging
  • Cellular and Molecular Neuroscience
  • Neurology

Cite this

Trends in the prevalence of dementia in Japan. / Dodge, Hiroko; Buracchio, Teresa J.; Fisher, Gwenith G.; Kiyohara, Yutaka; Meguro, Kenichi; Tanizaki, Yumihiro; Kaye, Jeffrey.

In: International Journal of Alzheimer's Disease, 2012.

Research output: Contribution to journalArticle

Dodge, Hiroko ; Buracchio, Teresa J. ; Fisher, Gwenith G. ; Kiyohara, Yutaka ; Meguro, Kenichi ; Tanizaki, Yumihiro ; Kaye, Jeffrey. / Trends in the prevalence of dementia in Japan. In: International Journal of Alzheimer's Disease. 2012.
@article{076881566aa344cfb27c6817e1a16a45,
title = "Trends in the prevalence of dementia in Japan",
abstract = "There is a paucity of data regarding trends in dementia and its subtype prevalence in Japan. Our aims in the current paper are to: (1) summarize epidemiological studies of dementia in Japan including relevant details of study protocol and diagnostic criteria, (2) compare the age-specific prevalence of all-cause dementia among studies, and (3) assess the trends in Alzheimer's disease (AD) versus vascular dementia (VaD) over time. We reviewed diagnostic criteria, all-cause dementia prevalence, and the AD/VaD ratio from 8 large population studies of dementia in Japan. Compared with the Okinawa 1992 study, studies conducted in 1994, 1998, 2005, and 2008 had a higher prevalence of all-cause dementia using Poisson regression models, after controlling for age and sex. In contrast to the US and some European countries, all-cause dementia prevalence is increasing in Japan. The prevalence of AD as opposed to VaD seems to be increasing over time, but large variability in diagnostic criteria, possible regional variability, and differences in prevalence of subtypes of dementia between men and women make it difficult to draw a conclusion about this trend at the national level. Further studies, for example, comparing the population attributable risk of vascular diseases to the prevalence and incidence of dementia could help to clarify the regional variations in etiological subtypes.",
author = "Hiroko Dodge and Buracchio, {Teresa J.} and Fisher, {Gwenith G.} and Yutaka Kiyohara and Kenichi Meguro and Yumihiro Tanizaki and Jeffrey Kaye",
year = "2012",
doi = "10.1155/2012/956354",
language = "English (US)",
journal = "International Journal of Alzheimer's Disease",
issn = "2090-8024",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Trends in the prevalence of dementia in Japan

AU - Dodge, Hiroko

AU - Buracchio, Teresa J.

AU - Fisher, Gwenith G.

AU - Kiyohara, Yutaka

AU - Meguro, Kenichi

AU - Tanizaki, Yumihiro

AU - Kaye, Jeffrey

PY - 2012

Y1 - 2012

N2 - There is a paucity of data regarding trends in dementia and its subtype prevalence in Japan. Our aims in the current paper are to: (1) summarize epidemiological studies of dementia in Japan including relevant details of study protocol and diagnostic criteria, (2) compare the age-specific prevalence of all-cause dementia among studies, and (3) assess the trends in Alzheimer's disease (AD) versus vascular dementia (VaD) over time. We reviewed diagnostic criteria, all-cause dementia prevalence, and the AD/VaD ratio from 8 large population studies of dementia in Japan. Compared with the Okinawa 1992 study, studies conducted in 1994, 1998, 2005, and 2008 had a higher prevalence of all-cause dementia using Poisson regression models, after controlling for age and sex. In contrast to the US and some European countries, all-cause dementia prevalence is increasing in Japan. The prevalence of AD as opposed to VaD seems to be increasing over time, but large variability in diagnostic criteria, possible regional variability, and differences in prevalence of subtypes of dementia between men and women make it difficult to draw a conclusion about this trend at the national level. Further studies, for example, comparing the population attributable risk of vascular diseases to the prevalence and incidence of dementia could help to clarify the regional variations in etiological subtypes.

AB - There is a paucity of data regarding trends in dementia and its subtype prevalence in Japan. Our aims in the current paper are to: (1) summarize epidemiological studies of dementia in Japan including relevant details of study protocol and diagnostic criteria, (2) compare the age-specific prevalence of all-cause dementia among studies, and (3) assess the trends in Alzheimer's disease (AD) versus vascular dementia (VaD) over time. We reviewed diagnostic criteria, all-cause dementia prevalence, and the AD/VaD ratio from 8 large population studies of dementia in Japan. Compared with the Okinawa 1992 study, studies conducted in 1994, 1998, 2005, and 2008 had a higher prevalence of all-cause dementia using Poisson regression models, after controlling for age and sex. In contrast to the US and some European countries, all-cause dementia prevalence is increasing in Japan. The prevalence of AD as opposed to VaD seems to be increasing over time, but large variability in diagnostic criteria, possible regional variability, and differences in prevalence of subtypes of dementia between men and women make it difficult to draw a conclusion about this trend at the national level. Further studies, for example, comparing the population attributable risk of vascular diseases to the prevalence and incidence of dementia could help to clarify the regional variations in etiological subtypes.

UR - http://www.scopus.com/inward/record.url?scp=84874896051&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874896051&partnerID=8YFLogxK

U2 - 10.1155/2012/956354

DO - 10.1155/2012/956354

M3 - Article

JO - International Journal of Alzheimer's Disease

JF - International Journal of Alzheimer's Disease

SN - 2090-8024

M1 - 956354

ER -