TY - JOUR
T1 - Treatment of early stage thymic tumors
T2 - Surgery and radiation therapy
AU - Gielda, Benjamin T.
AU - Peng, Rick
AU - Coleman, Joy L.
AU - Thomas, Charles R.
AU - Cameron, Robert B.
PY - 2008
Y1 - 2008
N2 - Tumors of the thymus are an uncommon entity, constituting 30% and 15% of anterior mediastinal masses in adults and children, respectively. The majority of these tumors are thymomas, with thymic carcinomas less common, and thymic carcinoids exceedingly rare. Recognition of the distinct clinicopathologic behavior of various thymic neoplasms is crucial to providing optimal treatment. Evidence guiding the treatment of early stage thymic tumors is limited secondary to the low incidence and resulting lack of randomized data. Proper management requires a careful analysis of the available literature with particular attention paid to limitations of the existing studies. This article provides a discussion of the presentation, evaluation, diagnosis, surgical techniques, and treatment outcomes relevant to early stage thymomas, thymic carcinomas, and thymic carcinoid tumors. The role of radiation therapy in the management of early stage thymic tumors remains controversial and is discussed in detail.
AB - Tumors of the thymus are an uncommon entity, constituting 30% and 15% of anterior mediastinal masses in adults and children, respectively. The majority of these tumors are thymomas, with thymic carcinomas less common, and thymic carcinoids exceedingly rare. Recognition of the distinct clinicopathologic behavior of various thymic neoplasms is crucial to providing optimal treatment. Evidence guiding the treatment of early stage thymic tumors is limited secondary to the low incidence and resulting lack of randomized data. Proper management requires a careful analysis of the available literature with particular attention paid to limitations of the existing studies. This article provides a discussion of the presentation, evaluation, diagnosis, surgical techniques, and treatment outcomes relevant to early stage thymomas, thymic carcinomas, and thymic carcinoid tumors. The role of radiation therapy in the management of early stage thymic tumors remains controversial and is discussed in detail.
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U2 - 10.1007/s11864-008-0080-2
DO - 10.1007/s11864-008-0080-2
M3 - Review article
C2 - 19169830
AN - SCOPUS:70249089402
SN - 1527-2729
VL - 9
SP - 259
EP - 268
JO - Current treatment options in oncology
JF - Current treatment options in oncology
IS - 4-6
ER -