Treatment choice and quality of life in patients with choroidal melanoma

Karen J. Cruickshanks, Dennis G. Fryback, David M. Nondahl, Nancy Robinson, Ulker Keesey, Dayna S. Dalton, Dennis M. Robertson, Suresh R. Chandra, William F. Mieler, Z. Nicholas Zakov, Philip L. Custer, Lucian V. Del Priore, Daniel Albert

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Objective: To determine if quality of life differs between patients with choroidal melanoma treated with enucleation and those treated with radiation therapy. Materials and Methods: Patients treated for choroidal melanoma at 5 Midwest centers were asked to participate. There were 65 participants treated with enucleation and 82 treated with radiation therapy. Quality of life was assessed using the Medical Outcome Study Short Form 36 and the National Eye Institute Visual Function Questionnaire and by the Time-Tradeoff interview method. Results: The average length of follow-up was 4.9 years for the group treated with radiation therapy and 6.3 years for the group treated with enucleation (P = .05). After adjusting for age, sex, years of follow-up, and the number of chronic conditions, there were few differences in any of the quality-of-life measures by treatment status. Participants in the group treated with radiation therapy were more likely to have higher (better) scores on the Vitality and Mental Component subscales of the Medical Outcome Study Short Form 36 than participants treated with enucleation. There were no differences on the National Eye Institute Visual Function Questionnaire or the Time-Tradeoff measures of quality of life. Conclusion: Choice of treatment for choroidal melanoma does not seem to be associated with large differences in quality of life in long-term follow-up.

Original languageEnglish (US)
Pages (from-to)461-467
Number of pages7
JournalArchives of ophthalmology
Volume117
Issue number4
DOIs
StatePublished - Jan 1 1999
Externally publishedYes

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Melanoma
Quality of Life
Radiotherapy
National Eye Institute (U.S.)
Outcome Assessment (Health Care)
Therapeutics
Interviews
Surveys and Questionnaires

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Cruickshanks, K. J., Fryback, D. G., Nondahl, D. M., Robinson, N., Keesey, U., Dalton, D. S., ... Albert, D. (1999). Treatment choice and quality of life in patients with choroidal melanoma. Archives of ophthalmology, 117(4), 461-467. https://doi.org/10.1001/archopht.117.4.461

Treatment choice and quality of life in patients with choroidal melanoma. / Cruickshanks, Karen J.; Fryback, Dennis G.; Nondahl, David M.; Robinson, Nancy; Keesey, Ulker; Dalton, Dayna S.; Robertson, Dennis M.; Chandra, Suresh R.; Mieler, William F.; Zakov, Z. Nicholas; Custer, Philip L.; Del Priore, Lucian V.; Albert, Daniel.

In: Archives of ophthalmology, Vol. 117, No. 4, 01.01.1999, p. 461-467.

Research output: Contribution to journalArticle

Cruickshanks, KJ, Fryback, DG, Nondahl, DM, Robinson, N, Keesey, U, Dalton, DS, Robertson, DM, Chandra, SR, Mieler, WF, Zakov, ZN, Custer, PL, Del Priore, LV & Albert, D 1999, 'Treatment choice and quality of life in patients with choroidal melanoma', Archives of ophthalmology, vol. 117, no. 4, pp. 461-467. https://doi.org/10.1001/archopht.117.4.461
Cruickshanks KJ, Fryback DG, Nondahl DM, Robinson N, Keesey U, Dalton DS et al. Treatment choice and quality of life in patients with choroidal melanoma. Archives of ophthalmology. 1999 Jan 1;117(4):461-467. https://doi.org/10.1001/archopht.117.4.461
Cruickshanks, Karen J. ; Fryback, Dennis G. ; Nondahl, David M. ; Robinson, Nancy ; Keesey, Ulker ; Dalton, Dayna S. ; Robertson, Dennis M. ; Chandra, Suresh R. ; Mieler, William F. ; Zakov, Z. Nicholas ; Custer, Philip L. ; Del Priore, Lucian V. ; Albert, Daniel. / Treatment choice and quality of life in patients with choroidal melanoma. In: Archives of ophthalmology. 1999 ; Vol. 117, No. 4. pp. 461-467.
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