To be or NUCB2, is nesfatin the answer?

Michael A. Cowley, Kevin L. Grove

Research output: Contribution to journalShort surveypeer-review

30 Scopus citations


Signals from the hypothalamus govern food intake and energy balance. A new study describes nesfatin-1, a hypothalamic and brainstem peptide whose expression decreases during fasting. Although central treatment with nesfatin-1 inhibited food intake and nesfatin-1 blockade increased food intake, the role and mechanism of nesfatin in energy balance remains unclear.

Original languageEnglish (US)
Pages (from-to)421-422
Number of pages2
JournalCell Metabolism
Issue number6
StatePublished - Dec 2006
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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