Time-resolved photon emission from layered turbid media

Andreas H. Hielscher, Hanli Liu, Britton Chance, Frank K. Tittel, Steven L. Jacques

Research output: Contribution to journalArticle

93 Scopus citations

Abstract

We present numerical and experimental results of time-resolved emission profiles from various layered turbid media. Numerical solutions determined by time-resolved Monte Carlo simulations are compared with measurements on layered-tissue phantoms made from gelatin. In particular, we show that in certain cases the effects of the upper layers can be eliminated. As a practical example, these results are used to analyze in vivo measurements on the human head. This demonstrates the influence of skin, skull, and meninges on the determination of the blood oxygenation in the brain.

Original languageEnglish (US)
Pages (from-to)719-728
Number of pages10
JournalApplied Optics
Volume35
Issue number4
DOIs
StatePublished - Feb 1 1996
Externally publishedYes

Keywords

  • Blood oxygenation
  • Brain
  • Diffusion theory
  • Monte Carlo simulation
  • Multilayer
  • Photon counting
  • Photon migration
  • Reflectance
  • Scattering
  • Time-resolved
  • Tissue phantom

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering

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  • Cite this

    Hielscher, A. H., Liu, H., Chance, B., Tittel, F. K., & Jacques, S. L. (1996). Time-resolved photon emission from layered turbid media. Applied Optics, 35(4), 719-728. https://doi.org/10.1364/AO.35.000719