Thoracic primary central nervous system melanoma and lumbar schwannoma of complex neurocristopathy: Case report

Aaron Chance, Jesse J. Liu, Jeffrey S. Raskin, Viktor Zherebitskiy, Sakir H. Gultekin, Ahmed M. Raslan

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Complex neurocristopathy, a disorder resulting from the aberrant proliferation of tissues derived from neural crest cells, has been previously reported in 2 patients, both involving ophthalmic melanoma and other tumors. One patient had a periorbital neurofibroma, sphenoid wing meningioma, and choroid juxtapapillary meningioma. The other patient had a choroidal melanoma and an optic nerve sheath meningioma. The authors describe clinical and pathological findings in a patient who underwent resection of 2 distinct lesions: primary CNS melanoma at T-12 and an L-5 schwannoma. Clinical and histopathological findings of the case are reviewed. To the authors' knowledge, this is the first patient to present with complex neurocristopathy involving both a spinal melanoma and schwannoma.

Original languageEnglish (US)
Pages (from-to)780-783
Number of pages4
JournalJournal of Neurosurgery: Spine
Volume23
Issue number6
DOIs
StatePublished - Dec 2015

Keywords

  • Complex neurocristopathy
  • Melanocytoma
  • Oncology
  • Schwannoma
  • Spinal melanoma

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology

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