Abstract
The Toxicology Investigators Consortium (ToxIC) Case Registry was established by the American College of Medical Toxicology in 2010. The Registry contains data from participating sites with the agreement that all bedside medical toxicology consultations will be entered. Currently, 83% of accredited medical toxicology fellowship programs in the USA participate. The Registry continues to grow each year, and as of 31 December 2016, a new milestone was reached, with more than 50,000 cases reported since its inception. The objective of this seventh annual report is to summarize the Registry’s 2016 data and activity with its additional 8529 cases. Cases were identified for inclusion in this report by a query of the ToxIC database for any case entered from 1 January to 31 December 2016. Detailed data was collected from these cases and aggregated to provide information which includes the following: demographics (age, gender, race, ethnicity, HIV status), reason for medical toxicology evaluation (intentional pharmaceutical exposure, envenomation, withdrawal from a substance), agent and agent class, clinical signs and symptoms (vital sign abnormalities, organ system dysfunction), treatments and antidotes administered, fatality and life support withdrawal data. Fifty percent of cases involved females, and adults aged 19–65 were the most commonly reported. There were 86 patients (1.0%) with HIV-positive status known. Non-opioid analgesics were the most commonly reported agent class, with acetaminophen the most common agent reported. There were 126 fatalities reported in 2016 (1.5% of cases). Major trends in demographics and exposure characteristics remained similar overall with past years’ reports. While treatment interventions were commonly required, fatalities were rare.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 203-226 |
| Number of pages | 24 |
| Journal | Journal of Medical Toxicology |
| Volume | 13 |
| Issue number | 3 |
| DOIs | |
| State | Published - Aug 1 2017 |
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Keywords
- Epidemiology
- Medical toxicology
- Overdose
- Poisonings
ASJC Scopus subject areas
- Toxicology
- Health, Toxicology and Mutagenesis
Cite this
The Toxicology Investigators Consortium Case Registry—the 2016 Experience. / On behalf of the Toxicology Investigators Consortium Study Group.
In: Journal of Medical Toxicology, Vol. 13, No. 3, 01.08.2017, p. 203-226.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Toxicology Investigators Consortium Case Registry—the 2016 Experience
AU - On behalf of the Toxicology Investigators Consortium Study Group
AU - Farrugia, Lynn A.
AU - Rhyee, Sean H.
AU - Calello, Diane P.
AU - Campleman, Sharan L.
AU - Riederer, Anne M.
AU - Malashock, Hannah R.
AU - Pizon, Anthony
AU - Wiegand, Timothy
AU - Wax, Paul M.
AU - Brent, Jeffrey
AU - Aks, S. E.
AU - Algren, D. A.
AU - Alwasiyah, D.
AU - Beauchamp, G.
AU - Bentur, Y.
AU - Beuhler, M. C.
AU - Boyle, K. L.
AU - Bruccoleri, R. E.
AU - Burns, M. M.
AU - Cahana, A.
AU - Cannon, R. D.
AU - Caravati, E. M.
AU - Carey, J. L.
AU - Chhabra, N.
AU - Chomin, J.
AU - Christian, M. R.
AU - Conner, K.
AU - Cook, M. D.
AU - Cumpston, K. L.
AU - Dissanayake, V.
AU - Dribben, W. H.
AU - Eisenga, B. H.
AU - Engebretsen, K. M.
AU - Falkowitz, D.
AU - Farkas, A.
AU - Fenton, A.
AU - Froberg, B. A.
AU - Furmaga, J. F.
AU - Ganetsky, M.
AU - Garlich, F.
AU - Geib, A. J.
AU - Gorodetsky, R.
AU - Greene, S.
AU - Greller, H. A.
AU - Gummin, D. D.
AU - Hart, K.
AU - Hendrickson, R. G.
AU - Hendrickson, Robert
AU - Hoyte, C. O.
AU - Kusin, Shana
PY - 2017/8/1
Y1 - 2017/8/1
N2 - The Toxicology Investigators Consortium (ToxIC) Case Registry was established by the American College of Medical Toxicology in 2010. The Registry contains data from participating sites with the agreement that all bedside medical toxicology consultations will be entered. Currently, 83% of accredited medical toxicology fellowship programs in the USA participate. The Registry continues to grow each year, and as of 31 December 2016, a new milestone was reached, with more than 50,000 cases reported since its inception. The objective of this seventh annual report is to summarize the Registry’s 2016 data and activity with its additional 8529 cases. Cases were identified for inclusion in this report by a query of the ToxIC database for any case entered from 1 January to 31 December 2016. Detailed data was collected from these cases and aggregated to provide information which includes the following: demographics (age, gender, race, ethnicity, HIV status), reason for medical toxicology evaluation (intentional pharmaceutical exposure, envenomation, withdrawal from a substance), agent and agent class, clinical signs and symptoms (vital sign abnormalities, organ system dysfunction), treatments and antidotes administered, fatality and life support withdrawal data. Fifty percent of cases involved females, and adults aged 19–65 were the most commonly reported. There were 86 patients (1.0%) with HIV-positive status known. Non-opioid analgesics were the most commonly reported agent class, with acetaminophen the most common agent reported. There were 126 fatalities reported in 2016 (1.5% of cases). Major trends in demographics and exposure characteristics remained similar overall with past years’ reports. While treatment interventions were commonly required, fatalities were rare.
AB - The Toxicology Investigators Consortium (ToxIC) Case Registry was established by the American College of Medical Toxicology in 2010. The Registry contains data from participating sites with the agreement that all bedside medical toxicology consultations will be entered. Currently, 83% of accredited medical toxicology fellowship programs in the USA participate. The Registry continues to grow each year, and as of 31 December 2016, a new milestone was reached, with more than 50,000 cases reported since its inception. The objective of this seventh annual report is to summarize the Registry’s 2016 data and activity with its additional 8529 cases. Cases were identified for inclusion in this report by a query of the ToxIC database for any case entered from 1 January to 31 December 2016. Detailed data was collected from these cases and aggregated to provide information which includes the following: demographics (age, gender, race, ethnicity, HIV status), reason for medical toxicology evaluation (intentional pharmaceutical exposure, envenomation, withdrawal from a substance), agent and agent class, clinical signs and symptoms (vital sign abnormalities, organ system dysfunction), treatments and antidotes administered, fatality and life support withdrawal data. Fifty percent of cases involved females, and adults aged 19–65 were the most commonly reported. There were 86 patients (1.0%) with HIV-positive status known. Non-opioid analgesics were the most commonly reported agent class, with acetaminophen the most common agent reported. There were 126 fatalities reported in 2016 (1.5% of cases). Major trends in demographics and exposure characteristics remained similar overall with past years’ reports. While treatment interventions were commonly required, fatalities were rare.
KW - Epidemiology
KW - Medical toxicology
KW - Overdose
KW - Poisonings
UR - http://www.scopus.com/inward/record.url?scp=85026538607&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85026538607&partnerID=8YFLogxK
U2 - 10.1007/s13181-017-0627-3
DO - 10.1007/s13181-017-0627-3
M3 - Article
C2 - 28766237
AN - SCOPUS:85026538607
VL - 13
SP - 203
EP - 226
JO - Journal of Medical Toxicology
JF - Journal of Medical Toxicology
SN - 1556-9039
IS - 3
ER -